• The first main type of sex-cord stromal tumor is a granulosa-theca cell tumor. (osmosis.org)
  • With sex cord-stromal ovarian cancer , Ovarian refers to " ovary ", of which women have two that sit along either side of the uterus . (osmosis.org)
  • Ovarian cancer is a cancerous tumor of an ovary. (wikipedia.org)
  • The ovary is made up of three different cell types including epithelial cells, germ cells, and stromal cells. (wikipedia.org)
  • Stromal tumors of the ovary include germ-cell tumors, sex-cord stromal tumors, and other more rare types. (medscape.com)
  • Differences (disorders) of sex development (DSDs), formerly termed intersex conditions, are seen in infants who are born with ambiguous or abnormal genitalia and may have indeterminate phenotypic sex. (medscape.com)
  • However, the paradigm of early gender assignment has been challenged by the results of clinical and basic science research, which show that gender identity development likely begins in utero and may not be the same as chromosomal or phenotypic sex. (medscape.com)
  • In 2006, the Lawson Wilkins Pediatric Endocrine Society (LWPES) and the European Society for Paediatric Endocrinology (ESPE) published proposed changes to the previously used nomenclature and definitions of disorders in which the development of chromosomal, gonadal, or phenotypic sex is atypical. (medscape.com)
  • On the other hand, phenotypic sex is determined by the primary sexual characteristics, so the genitalia and gonads, as well as the secondary sexual characteristics, such as breast and muscle development, as well as body hair and fat distribution . (osmosis.org)
  • Juvenile granulosa cell tumor (JGCT) is an uncommon ovarian tumor. (bvsalud.org)
  • Through genetic studies of exome sequence, it was found that gliomatosis is genetically identical to the parent ovarian tumor and developed from cells that disseminate from the ovarian teratoma. (mdwiki.org)
  • Epithelial ovarian carcinoma is the most common type of ovarian cancer, comprising more than 95% of cases. (wikipedia.org)
  • The ovaries consist of different types of tissue ( epithelial , germ cells, and sex cord tissue), which may give rise to benign or malignant tumors . (amboss.com)
  • Epithelial ovarian tumors are the most common tumor subtype. (amboss.com)
  • Various cell lineages such as the epithelial glandular cells and the stromal spindle cells are involved. (ijpmonline.org)
  • According to statistics, 40-60% of cases of infertility are caused by violations of the reproductive function of women, 5-6% are men, 27-48% are caused by violations in both spouses, and in 5% of cases it is not possible to identify the cause of infertility. (clomid-info.com)
  • Comprised exclusively of clinical cases covering abnormal female puberty and its clinical management, this concise, practical casebook will provide clinicians in reproductive endocrinology, gynecology and pediatrics with the best real-world strategies to properly diagnose and treat the various forms of the condition they may encounter. (nshealth.ca)
  • In most cases today, clinicians can promptly make an accurate diagnosis and counsel parents on therapeutic options. (medscape.com)
  • The pathologic diagnosis was a testicular adult granulosa cell tumor. (bvsalud.org)
  • The aim of cytoreductive surgery is to confirm the diagnosis, define the extent of disease, and resect all visible tumor. (medscape.com)
  • Therefore, in many cases, especially with the full diagnosis codes, much detail has necessarily been omitted. (cdc.gov)
  • If any of those cells starts to divide uncontrollably, it can either form a benign tumor which means that it doesn't invade nearby tissue or spread to other parts of the body , or it can be a malignant tumor which means that it can invade nearby tissue and spread to other parts of the body . (osmosis.org)
  • Compared with benign tumor cells, malignant tumor cells have key features like not having a clearly defined border or like having slightly less organized nuclei. (osmosis.org)
  • We report 23 cases of tumors of the salivary gland comprising 18 cases of carcinoma ex pleomorphic adenoma, four cases of carcinosarcoma of the parotid and one case of benign metastasizing pleomorphic adenoma. (ijpmonline.org)
  • Solitary or multiple benign hepatic vascular tumors, usually occurring in women of 20-50 years of age. (lookformedical.com)
  • The term sex cord refers to an embryonic structures that develop into ovarian follicles and stromal cells are the connective tissue of any organ. (osmosis.org)
  • So a sex cord-stromal ovarian cancer is a type of tumor that develops from either ovarian follicle cells or connective tissue cells . (osmosis.org)
  • Under the microscope, these tumors classically develop little fluid pockets scattered throughout the tissue that are called Call-Exner bodies. (osmosis.org)
  • Sex cord-stromal ovarian cancer is a type of tumor that develops from either ovarian follicle cells, or connective tissue cells . (osmosis.org)
  • The LWPES-ESPE terminology mainly reflects the chromosomal sex or the gonadal tissue associated with the disorder. (medscape.com)
  • A teratoma is a tumor made up of several different types of tissue , such as hair , muscle , teeth , or bone . (mdwiki.org)
  • Mature teratoma of the mediastinum: A horizontal slice of the resected tumor reveals fibrofatty tissue, calcified areas, and a few cystic spaces lined with smooth membrane and containing a hair. (mdwiki.org)
  • An increase in the number of cells in a tissue or organ without tumor formation. (lookformedical.com)
  • Endometrial hyperplasia is classified by its cytology and glandular tissue. (lookformedical.com)
  • Ovarian borderline tumors, also known as low malignant potential (LMP) ovarian tumors, do not cause an increase in CA125 levels and are not identifiable with an ultrasound. (wikipedia.org)
  • Leiomyoma with bizarre nuclei: a morphological, immunohistochemical and molecular analysis of 31 cases. (uchicago.edu)
  • OBJECTIVE: Adult granulosa cell tumors (AGCTs) are rare malignancies that accounts for approximately 1% of ovarian neoplasms. (bvsalud.org)
  • The occurrence of various malignancies suggests that this phenomenon is not very uncommon and should be looked for when reporting a mixed tumor. (ijpmonline.org)
  • Malignancy arising in mixed tumors of the salivary gland is a distinct entity that can occur sporadically or in association with a background of pleomorphic adenoma. (ijpmonline.org)
  • GU tract pathologies can arise potentially at any stage of a person's life: newborns and infants can start showing signs and symptoms of congenital GU abnormalities, early or delayed puberty can become a burden for adolescents, STDs remain a major public health concern in sexually active teens and adults, and the potential for gonadal or cervical malignancy is constantly looming in particular cases. (lecturio.com)
  • Conclusion: This report provides an approach to an uncommon case of a very large and heavy GCT. (bvsalud.org)
  • When these cells become abnormal, they have the ability to divide and form tumors. (wikipedia.org)
  • In both cases, investigation of abnormal androgen production by the mother must be performed immediately after delivery. (health.am)
  • Cases included illustrate different causes of abnormal puberty as well as management strategies, including congenital anomalies, endocrine disorders, issues of constitutional delay, obesity, eating disorders, ovarian cancer and the effect of pharmacology, among others. (nshealth.ca)
  • those who have X and Y sex chromosomes are typically considered genetically males, while those who only have X chromosomes are typically considered genetically females. (osmosis.org)
  • [5] Ovarian teratomas represent about a quarter of ovarian tumors and are typically noticed during middle age. (mdwiki.org)
  • Pelvic ultrasound shows a thickened endometrial stripe. (osmosis.org)
  • The typical symptoms of an LMP tumor can include abdominal distension or pelvic pain. (wikipedia.org)
  • In 2020, new cases occurred in approximately 313,000 women. (wikipedia.org)
  • And these are the most common malignant stromal tumors and they're associated with middle-aged women. (osmosis.org)
  • Less common types of ovarian cancer include germ cell tumors and sex cord stromal tumors. (wikipedia.org)
  • Background: Granulosa cell tumors (GCTs) are the most common ovarian tumors in mares. (bvsalud.org)
  • Ovarian cancer is the most common cause of cancer death from gynecologic tumors in the United States. (medscape.com)
  • Teratomas occur in the coccyx in about one in 30,000 newborns, making them one of the most common tumors in this age group. (mdwiki.org)
  • Because of the enormous dimensions of the GCT, intra-abdominal partial resection of the tumor using a tenotomy knife was necessary to exteriorize the ovarian pedicle. (bvsalud.org)
  • T, and H3F3A K28R mutations in this case. (bvsalud.org)
  • Case Description: A 7-year-old mare was referred to the department for horses due to suspicion of a large colon impaction. (bvsalud.org)
  • Ovarian tumors include luteoma of pregnancy, arrhenoblastoma, hilar-cell tumor, masculinizing ovarian stromal cell tumor, and Krukenberg tumor. (health.am)
  • reports include cases of partial cranial bones , long bones and a rudimentary beating heart. (mdwiki.org)
  • Arise from sex cord cells (e.g. (amboss.com)
  • Rupture of a mucinous cystadenoma or cystadenocarcinoma leading to the spread of tumor cells throughout the peritoneum . (amboss.com)
  • They are a type of germ cell tumor (a tumor that begins in the cells that give rise to sperm or eggs ). (mdwiki.org)
  • Gliomatosis peritoneii, which presents as a deposition of mature glial cells in the peritoneum, is almost exclusively seen in conjunction with cases of ovarian teratoma. (mdwiki.org)
  • Untreated maternal virilizing CAH is another potential cause, though androgen-secreting adrenal tumor in the mother is rare. (health.am)
  • Immature teratoma has one of the lowest rates of somatic mutation of any tumor type and results from one of five mechanisms of meiotic failure. (mdwiki.org)
  • These tumors often end up producing way too much estradiol, and this can cause very specific hormone associated symptoms like uterine bleeding , breast tenderness, and early puberty in young girls. (osmosis.org)
  • Granulosa-theca cell tumors produce excess estradiol, which can cause very specific hormone-associated symptoms like uterine bleeding , breast tenderness, and early puberty in young girls. (osmosis.org)
  • In most cases, symptoms exist for several months before being recognized and diagnosed. (wikipedia.org)
  • [4] Symptoms may be minimal if the tumor is small. (mdwiki.org)
  • In rare cases, GCTs cause hemoperitoneum as a result of the rapid growth of the tumor. (bvsalud.org)
  • BACKGROUND: The adult granulosa cell tumor of the testis is a rare sex-cord/stromal tumor, with a potentiality for late recurrence and metastasis. (bvsalud.org)
  • In this regard, in many cases the fetus in fetu is reported to occupy a fluid-filled cyst within a mature teratoma. (mdwiki.org)
  • However, because of its high case fatality rate, listeriosis ranks among the most frequent causes of death due to foodborne illness, ranking second after salmonellosis. (ijpmonline.org)
  • Most cases of ovarian cancer develop after menopause. (wikipedia.org)
  • Some of these tumors are granulosa-theca cell tumors and Sertoli-Leydig cell tumors. (osmosis.org)
  • Sertoli-Leydig cell tumors can secrete excess testosterone , which can cause women to have more masculine features like hirsutism , which is increased hair growth. (osmosis.org)
  • Okay, now based on their initial presentation, both Clay and Jessie seem to have some form of disorder of sexual development and sex hormones . (osmosis.org)
  • Because of its rarity, this tumor is poorly understood, particularly in terms of its molecular features. (bvsalud.org)
  • Is defined as the inability to conceive a child with regular sex without contraception for 12 months, provided the partners are of childbearing age. (clomid-info.com)