Corynebacterium ulcerans may cause diphtheria in humans and caseous lymphadenitis in animals. (cdc.gov)
Moreover, C. ulcerans and C. pseudotuberculosis may produce phospholipase D, the major virulence factor involved in caseous lymphadenitis, which is a disease that mainly affects sheep, goats, and horses ( 3 ). (cdc.gov)
Caseous lymphadenitis (CL) is a chronic, contagious bacterial disease that manifests clinically as abscesses of peripheral and/or internal lymph nodes and organs. (msdvetmanual.com)
The purpose of this study, through use of Polymerase Chain Reaction (PCR), was to verify the presence of virulence genes of phospholipase D (PLD), integral membrane protein (FagA), iron enterobactin transporter (FagB), ATP binding cytoplasmic membrane protein (FagC) and iron siderophore binding protein (FagD) in 168 isolates of C. pseudotuberculosis obtained from cases of caseous lymphadenitis in goats and sheep. (scielo.org)
In phylogenetic trees based on concatenated protein sequences or 16S rRNA, the genus Corynebacterium forms a distinct clade, within which is a distinct subclade, cluster I. The cluster is made up of the species C. diphtheriae, C. pseudotuberculosis, C. ulcerans, C. aurimucosum, C. glutamicum, and C. efficiens. (wikipedia.org)
Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that belongs to the so-called CMN ( Corynebacterium-Mycobacterium-Nocardia ) group, a distinct subgroup of the Actinobacteria that also includes other highly important bacterial pathogens, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis . (biomedcentral.com)
The Corynebacterium species C. diphtheriae , C. ulcerans , and C. pseudotuberculosis form the C. diphtheriae group, as shown by 16S rRNA gene sequence analysis ( 1 ). (cdc.gov)
In some endemic locations, such as India, 44% of throat and nasal swabs tested positive for C diphtheriae and Corynebacterium pseudodiphtheriticum . (medscape.com)
Three strains of C diphtheriae are recognized, in decreasing order of virulence: gravis, intermedius, and mitis. (medscape.com)
Goats3
During 1985-88, in sheep and goats, 7.01% of the animals were found positive for BTV antibodies on AGPT. (cswri.res.in)
The management system also found to affect the sero-prevalence of BTD and it was higher in migratory flocks (63.29% in sheep to 84.84% in goats) compared to stationary flocks (35.03% in sheep to 72.88% in goats). (cswri.res.in)
Caseous lymphadenits (CL) is a chronic and subclinical disease that affects goats and sheep and, consequently, causes economic losses, especially to small producers. (scielo.org)
Sheep1
Mycoplasma strains have also been isolated from sheep having respiratory distress and typed as M. agalactiae by using reference sera (National Collection of Type Culture, London). (cswri.res.in)
Virulence3
Comparative analyses of the exoproteomes of two C. pseudotuberculosis strains, in addition to comparison with other experimentally determined corynebacterial exoproteomes, were helpful to gain novel insights into the contribution of the exported proteins in the virulence of this bacterium. (biomedcentral.com)
In fact, one might expect that the majority of the virulence determinants of C. pseudotuberculosis would be present in the exoproteome, i.e . the entire set of bacterial proteins found in the extracellular milieu [ 7 ]. (biomedcentral.com)
All virulence factors analyzed were found more frequently among isolates collected in the viscera of animals with CL, indicating a multifactorial nature, as well as variations, in the invasive potential of C. pseudotuberculosis strains. (scielo.org)
Ovine1
A further two Cp strains, an Australian ovine and a North American equine isolate, as well as C. ulcerans NCTC 12077 were sequenced for comparison. (gla.ac.uk)
Species7
Two examples of CSIs are a two-amino-acid insertion in a conserved region of the enzyme phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase and a three-amino-acid insertion in acetate kinase, both of which are found only in Corynebacterium species. (wikipedia.org)
Additionally, 16 conserved signature proteins, which are uniquely found in Corynebacterium species, have been identified. (wikipedia.org)
Also, 21 conserved signature proteins are found only in members of cluster I. Another cluster has been proposed, consisting of C. jeikeium and C. urealyticum, which is supported by the presence of 19 distinct conserved signature proteins which are unique to these two species. (wikipedia.org)
C. ulcerans is a zoonotic pathogen and has been found in various animal species that have contact with humans ( 5 ). (cdc.gov)
C. ulcerans is most closely related to C. pseudotuberculosis , and distinction between these species is often difficult when using standard bacteriological methods ( 5 ). (cdc.gov)
In general the agents implicated in etiology of respiratory syndrome include a wide spectra of viruses such as PI 3, Adeno and Reo viruses, bacterial species such as Hemophilus, Bordetella, Pasteurella, Corynebacterium, Mycoplasma and Chlamydia along with a chain of predisposing factors mainly the environmental and managemental fluctuations. (cswri.res.in)
Genus5
Corynebacterium (/kɔːˈraɪnəbækˌtɪəriəm, -ˈrɪn-/) is a genus of Gram-positive bacteria and most are aerobic. (wikipedia.org)
The genus Corynebacterium was created by Lehmann and Neumann in 1896 as a taxonomic group to contain the bacterial rods responsible for causing diphtheria. (wikipedia.org)
Three of these have homologs found in the genus Dietzia, which is believed to be the closest related genus to Corynebacterium. (wikipedia.org)
The principal features of the genus Corynebacterium were described by Collins and Cummins, for Coryn Taylor in 1986. (wikipedia.org)
Phylogenetic analyses of the Corynebacterium genus were performed using house-keeping loci but also secreted protein loci from Cp 3/99-5. (gla.ac.uk)
Ulcerans2
The aim of this study was to comprehensively characterize 13 C. ulcerans strains isolated from game animals in Germany. (cdc.gov)
Strains of C. ulcerans were isolated during routine bacteriological investigations in conjunction with necropsies of wild animals that were found dead or that had suspicious lesions during 1997-2013. (cdc.gov)
Although prevalence of CL varies by region and country, it is found worldwide and is of major concern for small ruminant producers in North America. (msdvetmanual.com)
In goat kids it may be Navel infection arthritis caused by corynebacterium pyogensis, streptoceoci, staphylococci, while non-superative arthritis is by birth, caused due to deficiency of vitamins and minerals. (health-articles.net)
Proteins2
44 proteins were commonly identified in two different strains, isolated from distinct hosts, then composing a core C. pseudotuberculosis exoproteome. (biomedcentral.com)
Moreover, evidence could be found for probable non-classical export of most of the remaining proteins. (biomedcentral.com)
Isolates1
it was found to be more similar to the equine Cp 1/06-A isolate which is the most diverged of the Cp isolates. (gla.ac.uk)
Genes1
FagA, FagB and PLD genes were detected in all 145 strains isolated from abscesses in superficial lymph nodes and in 23 strains isolated from viscera. (scielo.org)
Protein1
An optimized protocol of three-phase partitioning (TPP) was used to obtain the C. pseudotuberculosis exoproteins, and a newly introduced method of data-independent MS acquisition (LC-MS E ) was employed for protein identification and label-free quantification. (biomedcentral.com)
Group2
Strains of this group carrying lysogenic β-corynephages might produce the tox -encoded diphtheria toxin (DT) ( 2 ). (cdc.gov)
These strains all produce an identical toxin, but the gravis strain is potentially more virulent because it grows faster and depletes the local iron supply, allowing for earlier and greater toxin production. (medscape.com)
Search1
Enter search terms to find related veterinary topics, multimedia and more. (msdvetmanual.com)
Small1
Symptoms: It is an inflammation of urinary bladder, which show swelling of value, staining of perineum, frequent straining with small amount of urine, pus and blood in the urine, also show depression, anorexia and excessive thirst. (health-articles.net)
The use of the comparative intradermal tuberculin (CIT) test rather than a single intradermal tuberculin (SIT) test is usually preferred as a first option for diagnosis owing to the potential interference caused by environmental mycobacteria or Corynebacterium pseudotuberculosis infections [ 8 , 14 ]. (biomedcentral.com)
RRNA1
It was found that the products from the PCL1 promoter of rrnA play a pivotal role in rRNA synthesis during all stress conditions. (bvsalud.org)
Diphtheria toxin1
Strains of this group carrying lysogenic β-corynephages might produce the tox -encoded diphtheria toxin (DT) ( 2 ). (cdc.gov)
Phylogenetic1
Phylogenetic analyses of the Corynebacterium genus were performed using house-keeping loci but also secreted protein loci from Cp 3/99-5. (gla.ac.uk)
Spatial1
Spatial analysis in Δrrn strains showed substantial RNAP redistribution during moderate growth, with clustering increasing at cell endcaps, where the remaining rrn operons reside. (bvsalud.org)
Study1
The present study found M. caprae infection in OWC. (biomedcentral.com)
Beta1
In another review of antimicrobial treatment options for corynebacterial mastitis, Corynebacterium kroppenstedtii was susceptible to most antibiotics except beta lactams, while Corynebacterium tuberculostearicum was resistant to most antibiotics. (medscape.com)
Similar1
it was found to be more similar to the equine Cp 1/06-A isolate which is the most diverged of the Cp isolates. (gla.ac.uk)
Dead1
one was found dead, the other had been shot. (nih.gov)