Case anemia hemolytic. Medical search. Frequent questions

Two forms of cold antibody autoimmune hemolytic anemias are generally recognized: Donath-Landsteiner hemolytic anemia (DLHA) and cold agglutinin disease. (medscape.com)
Donath-Landsteiner hemolytic anemia (DLHA) is a result of cold-reacting antibody immunoglobulin (Ig) induced hemolytic response inside vessels leading to anemia and, thus, a cold antibody autoimmune hemolytic anemias (CAAHA). (wikipedia.org)
Chaplin H Jr: Clinical usefulness of specific antiglobulin reagents in autoimmune hemolytic anemias. (karger.com)

Exact signs and symptoms of DLHA are anemia-alike dyspnea palpitations fatigue pallor Hemolysis-alike jaundice dark urine pain Signs and symptoms that indicate a medical emergency and that the patients with DLHA require to be hospitalized Rapidly progressive anemia Worsening anemia Severe anemia Respiratory distress Circulatory shock Renal failure Severe infection Patient's condition is unstable that produces the need to closely monitor. (wikipedia.org)
This case encouraged us to investigate G6PD deficiency as a differential diagnosis of severe neonatal jaundice and hemolytic anemia despite the low prevalence in Japan. (springeropen.com)
We describe a neonatal case of G6PD deficiency that developed severe jaundice and acute hemolytic anemia in the absence of ABO incompatibilities. (springeropen.com)

Blood typing is supposed to be performed with every patient even if their anemia is mild since the hemoglobin can fall all of a sudden and require prompt blood transfusion. (wikipedia.org)
The term "anemia" means that the number of red blood cells in a person's blood is less than normal or the red blood cells don't contain enough hemoglobin . (daviddarling.info)
In sickle cell anemia , the body makes an abnormal type of hemoglobin. (daviddarling.info)
Initial investigations showed normochromic macrocytic anemia (hemoglobin: 8,7 g/dl MCV:117.3MCH:33) thrombopenia (platelets: 107 000) and 22% of reticulocytes, with a negativecoombs. (openpediatricmedicinejournal.com)
He suffered from moderate hemolytic anemia (hemoglobin levels ranging from 62 to 91 g/L) associated with macrocytosis, reticulocytosis, neutropenia, and hyperbilirubinemia. (biomedcentral.com)
Olson, p. 144-6] In some cases, methemoglobin-forming compounds cause denaturation of hemoglobin (Heinz bodies) followed by hemolytic anemia. (haz-map.com)
In a routine blood test, anemia is reported as a low hemoglobin or hematocrit. (webmd.com)
If you have anemia, your hemoglobin level will be low, too. (webmd.com)
In 1949, Itano and Pauling described the association of sickle cell anemia with abnormal hemoglobin Hb S, which could be differentiated from Hb A by electrophoresis. (medscape.com)

[ 1 , 2 , 3 ] (Whipple et al reported a case of autoimmune hemolytic anemia in which paroxysmal cold hemoglobinuria was caused by an IgA Donath-Landsteiner [D-L] antibody. (medscape.com)
The Donath-Landsteiner bithermic hemolytic test is a hemolytic assay in which the patient's serum is incubated with normal RBCs and complement at 0-4°C to allow the early components of complement to be fixed. (medscape.com)
For example, there was a case study reporting that autoimmune hemolytic anemia where an IgA Donath-Landsteiner denoted as [D-L] antibody appeared to cause Donath-Landsteiner cold hemoglobinuria. (wikipedia.org)
Acute Donath-Landsteiner hemolytic anemia is linked to viral infections such as: Adenovirus Congenital syphilis Coxsackievirus A9 Cytomegalovirus Epstein-Barr virus Influenza A Measles Mumps Parvovirus Varicella zoster virus Pathogens of bacterial infections that are linked to acute DLHA Mycoplasma pneumoniae Haemophilus influenzae Klebsiella pneumoniae Escherichia coli In addition to the commonly-seen causes mentioned above, oncologic reasons may also establish. (wikipedia.org)
The autoantibody responsible for Donath-Landsteiner hemolytic anemia (DLHA) is a cold-reacting immunoglobulin known as the D-L autoantibody. (medscape.com)
Donath-Landsteiner hemolytic anemia (DLHA) may be either idiopathic or secondary to an identifiable cause. (medscape.com)

In some types of hemolytic anemia, the body makes abnormal red blood cells that break down and hemolyze on their own. (daviddarling.info)
In other types of hemolytic anemia, the body's immune system , infections, certain drugs, or other agents attack normal red blood cells, causing them to hemolyze. (daviddarling.info)
The two main types of hemolytic anemia are inherited and acquired. (daviddarling.info)
There are many types of hemolytic anemia. (daviddarling.info)

Hereditary hemolytic anemias are a group of disorders with a variety of causes, including red cell membrane defects, red blood cell enzyme disorders, congenital dyserythropoietic anemias, thalassemia syndromes and hemoglobinopathies. (haematologica.org)
Congenital hemolytic anemias are present at birth and may or may not be inherited. (innvista.com)
Thus, our care covers congenital or acquired non-tumor diseases (anemias, coagulation disorders, etc.), as well as tumor diseases such as leukemia or myelodysplastic syndrome. (uhkt.cz)

A two-year old poodle dog has been seen, showing apathy and pale mucous .In the full blood exam it was observed a regenerative anemia with reticulocytosis and the presence of spherocytosis, indicating the IMHA diagnosis. (vin.com)
Kamesaki T, Oyamada T, Omine M, Ozawa K, Kajii E: Cut-off value of red-blood-cell-bound IgG for the diagnosis of Coombs-negative autoimmune hemolytic anemia. (karger.com)
Omine M, Kajii E, Kamesaki T, Karasawa M: A reference guide for diagnosis and treatment of autoimmunne hemolytic anemia. (karger.com)
Wilson's disease is not exceptional in children with hemolytic anemia, but another differential diagnosis must be excluded. (openpediatricmedicinejournal.com)
The diagnosis was 'mild iron deficiency anemia,' and iron therapy was prescribed. (cdc.gov)
Immune Mediated Hemolytic Anemia (IMHA) is a type II hypersensitivity disorder that is both recurrent and difficult to treat, resulting in almost half of affected animals being deceased within a year of diagnosis despite vigorous use of transfusions and immune suppressive medications. (civtedu.org)
Diagnosis − Beta thalassemia is diagnosed by looking for hemolytic anemia by examining a red blood cell smear under the microscope. (tutorialspoint.com)
If doctors suspect G6PD deficiency, blood tests usually can confirm the diagnosis and rule out other causes of anemia. (kidshealth.org)
CONCLUSIONS This case report shows that GSD can present with severe hemolytic anemia and metabolic acidosis at birth , and manifest with subsequent neurological impairment despite early diagnosis and treatment . (bvsalud.org)
SCD patients with fever, severe anaemia or pancytopenia should be investigated for early diagnosis and prompt treatment of IAH, which is a life- threatening haematological emergency for which transfusion therapy alone may not suffice. (bvsalud.org)

Whatever the process is that leads to destruction of RBC's, eventually the spleen will filter out these damaged RBC's leading to swelling of the spleen (splenomegaly) and anemia (a lowered RBC count in the blood). (nethealthbook.com)
Splenomegaly and hypersplenism are another reason why hemolytic anemias from changes outside of the RBC occur. (nethealthbook.com)
Splenomegaly, which occurs in about 50% of cases, is maximal during the 2nd and 3rd week and usually results in only a barely palpable splenic tip. (merckmanuals.com)
Canine babesiosis is characterized by varying degrees of hemolytic anemia, splenomegaly, thrombocytopenia, and fever. (auburn.edu)
Patients present nonmalignant lymphadenopathy and splenomegaly, autoimmune phenomena and in some cases even malignancy. (lu.se)

You may not have symptoms if the anemia is mild. (medlineplus.gov)
Contact your health care provider if you develop symptoms of hemolytic anemia. (medlineplus.gov)
The presence and severity of signs and symptoms of hemolytic anemia depend on the degree of hemolysis and the success of compensatory erythropoiesis. (innvista.com)
Symptoms of anemia - like fatigue or shortness of breath - happen because your organs aren't getting what they need to work the way they should. (webmd.com)
Symptoms − In some cases, there may be no symptoms and a person can be a carrier. (tutorialspoint.com)
In other cases, where two alleles are missing, there are some symptoms such as smaller than normal red blood cells (microcytic anemia). (tutorialspoint.com)
In this case, there will be symptoms but they will not be too severe. (tutorialspoint.com)
Major beta thalassemia (Cooley's anemia), occurs when there are severe symptoms such as problems with the bone marrow, and severe anemia. (tutorialspoint.com)
In these cases, the symptoms stop when the cause is gone. (kidshealth.org)
Others might have symptoms of hemolytic anemia if many RBCs are destroyed. (kidshealth.org)
Severe Hemolytic Anemia and Metabolic Acidosis at Birth with Glutathione Synthetase Deficiency and Progressive Neurological Symptoms on Follow-Up. (bvsalud.org)
The severe form of GSD is characterized by hemolytic anemia , metabolic acidosis with 5-oxoprolinuria, progressive neurological symptoms, and recurrent bacterial infections . (bvsalud.org)
This case report presents a male Japanese infant with severe hemolytic anemia and metabolic acidosis at birth caused by GSD, who developed progressive neurological symptoms on follow-up. (bvsalud.org)

Autoimmune manifestations include hemolytic anemia and thrombocytopenia. (lu.se)

But there are also warm antibody hemolytic anemias that lupus or certain drugs like levodopa can produce. (nethealthbook.com)

Hemolytic anemia is due to increased hemolysis (destruction) of red blood cells. (daviddarling.info)
We report a case of a child who developed recurrent hemolytic anemia associated with liver failure in the second hemolysis episode as the first manifestation of WD. (openpediatricmedicinejournal.com)
When hemolysis occurs earlier than the normal cycle, hemolytic anemia is the result. (innvista.com)
Seeding of the bacteria most often occurs from the gastrointestinal tract, biliary tract, or uterus, with hemolysis complicating the sepsis in 7%-15% of cases. (medscape.com)
LaDou, p. 264] Hemolysis has been reported in cases of poisoning by ingestion of arsenic and copper. (haz-map.com)

We report a fatal case of hemolytic uremic syndrome with urinary tract infection in Japan caused by Shiga toxin-producing Escherichia coli . (cdc.gov)

As no randomized clinical trials, case control or cohort studies regarding splenectomy in these disorders were found in the literature, recommendations for each disease were based on expert opinion and were subsequently critically revised and modified by the Splenectomy in Rare Anemias Study Group, which includes hematologists caring for both adults and children. (haematologica.org)
The hemolytic anemia is present in 17% at some point of the disease, although it is a rare initial clinical presentation. (openpediatricmedicinejournal.com)
The CDC/CSTE surveillance case definitions included in this report differ in their use of clinical, laboratory, and epidemiologic criteria to define cases. (cdc.gov)
Cases of canine babesiosis may present with a wide variety of clinical signs, ranging from a hyperacute, shockassociated, hemolytic crisis to an inapparent and subclinical infection. (auburn.edu)
The triad of hemolytic anemia, pancytopenia, and thrombosis makes PNH a unique clinical syndrome. (medscape.com)
The clinical course was complicated by a Coombs test positive haemolytic anaemia due to the production of autoantibodies against the rhesus "e' antigen, a non-glycosylated protein antigen. (bmj.com)
IAH in SCD manifests as febrile haemolytic crisis with clinical and laboratory features of severe anaemia or pancytopenia. (bvsalud.org)

However, except for hereditary spherocytosis for which the effectiveness of splenectomy has been well documented, the efficacy of splenectomy in other anemias within this group has yet to be determined and there are concerns regarding short- and long-term infectious and thrombotic complications. (haematologica.org)
Hemolytic anemia may be acquired or hereditary. (innvista.com)
Glucose phosphate isomerase (GPI) deficiency is a rare autosomal recessive disorder that causes hereditary nonspherocytic hemolytic anemia (HNSHA). (biomedcentral.com)
Glucose-6-phosphate isomerase (GPI) deficiency (MIM 613470), one of hereditary nonspherocytic hemolytic anemias (HNSHA), is a rare autosomal recessive hereditary disease caused by homozygous or compound heterozygous mutations of GPI gene on chromosome 19q13 [ 1 ]. (biomedcentral.com)
Hereditary spherocytosis (SFER-o-si-to-sis) is the most common cause of hemolytic anemia among people of Northern European descent. (hoacny.com)

Immune mediated hemolytic anemia (IMHA), also known as auto-immune mediated hemolytic anemia (AIHA, is a disease in which the body's immune system, which is designed to attack and kill germs, attacks and kills the body's own red blood cells. (petplace.com)
Although most cases of DAT-negative AIHA are thought to be caused by RBC-bound IgG, and combinatory serological analyses are recommended, the relative ratios of each mechanism have not been clarified. (karger.com)
Autoimmune hemolytic anemia (AIHA). (hoacny.com)
AIHA accounts for half of all cases of hemolytic anemia. (hoacny.com)

In the United States, sickle cell anemia occurs most often in African Americans. (daviddarling.info)
Sickle cell anemia is a serious, inherited disease. (hoacny.com)
In 1910, James Herrick, a Chicago physician, first described sickle cell anemia, "The shape of the RBC [red blood cell] was very irregular. (medscape.com)
In sickle cell anemia, the amino acid substitution valine for glutamate occurs on the beta chain at the sixth position. (medscape.com)
[ 7 ] About 8% of African Americans are heterozygous for Hb S. In the United States, sickle cell anemia primarily occurs in the Black population, with approximately 0.2% of African-American children afflicted by this disease. (medscape.com)
Sickle cell anemia is a homozygous-recessive disorder, that is, the individual receives two mutant genes that code for the variant beta globin chain. (medscape.com)

The immune-mediated hemolytic anemia (IMHA) is a disorder triggered by the destruction of the erythrocytes mediated by the presence of immunoglobulins or the complement system. (vin.com)
Thus, it appears that the combination of immunomodulatory and immunosuppressive can help in cases of IMHA that do not respond to the therapy with corticosteroids only. (vin.com)
While some cases of IMHA may be associated with a triggering event (cancer, infection, and perhaps even vaccinations), these events do not explain why the immune system misdirects its arsenal of weapons against the animal it is meant to protect. (petplace.com)
These examinations may help rule out causes of anemia other than IMHA, or may help identify triggers that preceded development of IMHA. (petplace.com)
Intravenous immunoglobulins, a product made from human blood, has been used with some success in a few cases of IMHA. (petplace.com)
A case report is presented here of a dog refractory to these measures who suffered IMHA twice within a six month timespan. (civtedu.org)
Does Garlic cause immune mediated hemolytic anemia (IMHA)? (petplace.com)
I was reading your article on Immune Mediated Hemolytic Anemia in Dogs and on page 3 it mentioned toxins such as onion and garlic being possible causes for IMHA. (petplace.com)
You read a blurb in our article about Immune-mediated Hemolytic Anemia in Dogs (IMHA) (also known as Auto-immune hemolytic anemia). (petplace.com)

In rare cases, surgery is needed to take out the spleen. (medlineplus.gov)
Treatment may require blood transfusions, and chelation therapy to remove excess iron due to the transfusions, and in some cases, spleen removal is needed. (tutorialspoint.com)

Treatments for chronic hemolytic anemia include blood transfusions, splenectomy, and supportive therapy. (biomedcentral.com)
Here, we reported a patient with compound heterozygous mutation of the GPI gene who presented chronic hemolytic anemic features and reviewed correlative literature. (biomedcentral.com)
The CDC Surveillance Coordination Group has established a steering committee that is charged with the development of a broad range of case definitions for noninfectious conditions (e.g., environmental or occupational conditions, chronic diseases, adverse reproductive health events, and injuries). (cdc.gov)
This can lead to inflammation of the liver and in chronic cases even to cirrhosis of the liver. (nethealthbook.com)
Older adults have a greater risk of anemia because they are more likely to have kidney disease or other chronic medical conditions. (webmd.com)
Go to Pediatric Chronic Anemia, Anemia of Prematurity, Fanconi Anemia, Pediatric Acute Anemia, and Pediatric Megaloblastic Anemia for complete information on these topics. (medscape.com)

DLHA, also known as paroxysmal cold hemoglobinuria, is an intravascular hemolytic anemia caused by a cold-reacting immunoglobulin (Ig). (medscape.com)
Most cases are due to polyclonal IgG, but IgM-induced DLHA has been described. (medscape.com)
In most cases, DLHA is associated with a sudden onset of hemoglobinuria after exposure to cold temperature. (medscape.com)
DLHA is an intravascular hemolytic anemia caused by a cold-reacting immunoglobulin (Ig). (medscape.com)

In case of hypersplenism, splenectomy is often performed. (lu.se)

Severe anemia can make heart disease, lung disease, or cerebrovascular disease worse. (medlineplus.gov)
For unknown reasons, there is an increased incidence of disease in the spring, with 40% of cases diagnosed in the months of May and June. (petplace.com)
Hemolytic Disease of the Newborn Hemolytic disease of the newborn is a condition in which red blood cells are broken down or destroyed by the mother's antibodies. (msdmanuals.com)

An 8-month-old boy and a 7-month-old girl presented with an acute, Coombs-positive auto-immune haemolytic anaemia and severe hepatitis. (nih.gov)

While IAEMH is associated with severe anaemia due to intravascular haemolysis caused by red cell invasion, oxidative injury, auto-antibodies, and/or pathogen-haem interaction, IAIMH is associated with haemophagocytic tri-lineage destruction of haematopoietic precursors in the bone marrow. (bvsalud.org)

The man was hospitalized in a coma, developed hemolytic anemia and methemoglobinemia, and died 28 days after admission (Shults et al. (cdc.gov)
It is not known why some individuals have methemoglobinemia and others experience hemolytic anemia after exposure to the same oxidants. (haz-map.com)

Hemolytic anemia occurs when the bone marrow isn't making enough red cells to replace the ones that are being destroyed. (medlineplus.gov)

Hemolytic anemias: red blood cell membrane and metabolic defects. (medlineplus.gov)

There are three main causes of anemia: blood loss, lower than normal levels of red blood cell production, or higher than normal rates of red blood cell destruction. (daviddarling.info)
Hemolytic anemia results when there is premature red cell destruction. (innvista.com)
In hemolytic anemia this destruction is the predominant event. (innvista.com)
Red blood cells (RBC) destruction leads to anemia. (petplace.com)
Rh incompatibility can result in destruction of the fetus's red blood cells, sometimes causing anemia that can be severe. (msdmanuals.com)

Hemolytic anemia can begin rapidly or come on gradually and can range from mild to severe. (daviddarling.info)

We'll start by providing an update on locally acquired malaria cases in the U.S. Between May and July of 2023, two U. S. counties reported locally acquired mosquito transmitted malaria due to Plasmodium vivax. (cdc.gov)
Am J Case Rep;24: e938396, 2023 Apr 13. (bvsalud.org)

Case Rep Gastroenterol (2022) 16 (3): 588-594. (karger.com)

Aplastic Anemia and MDS International Foundation Gordon Forgash Research Award. (rochester.edu)
Allogeneic hematopoietic stem cell transplantation is curative but it requires a histocompatible donor and is associated with significant morbidity and mortality, so it is reserved for severe cases of PNH with aplastic anemia or transformation to leukemia. (medscape.com)

In the inherited hemolytic anemias, one or more of the genes that control the production of red blood cells are defective, causing the bone marrow to make abnormal cells. (daviddarling.info)
PNH usually presents as hemolytic anemia, thrombosis, and smooth muscle dystonias, as well as bone marrow failure in some cases. (medscape.com)

A single case of death resulting from occupational exposure to methyl mercaptan has been located. (cdc.gov)
Acute hemolytic anemia after occupational arsine exposure has been described in the smelting, refining, and chemical industries. (haz-map.com)
Effect of occupational air pollutants on various histological types of lung cancer: a population based case-control study. (bmj.com)
Haemolytic anaemia in a case of occupational asthma due to maleic anhydride. (bmj.com)

The signs of anemia can be so mild that you might not even notice them. (webmd.com)

CDC and the Council of State and Territorial Epidemiologists (CSTE) have established a policy that requires state health departments to report cases of selected diseases ( Table_1 ) to CDC's National Notifiable Diseases Surveillance System (NNDSS) (1,2). (cdc.gov)
In October 1990, in collaboration with CSTE, CDC published Case Definitions for Public Health Surveillance (4), which, for the first time, provided uniform criteria for reporting cases to increase the specificity of reporting and improve the comparability of diseases reported from different geographic areas. (cdc.gov)
Women, young children, and people with long-term diseases are more likely to have anemia. (webmd.com)
And cancers and other diseases may also be a potential cause of anemia. (webmd.com)

When these things trigger a quick loss of red blood cells over a short time, it's called a hemolytic crisis . (kidshealth.org)

Liver and brain disorders are the main presentations, hemolytic anemia in WD is a rare inaugural symptom. (openpediatricmedicinejournal.com)
NSAIDs such as mefenamic acid have a number of adverse effects (digestive disorders, diarrhoea, haemolytic anaemia and seizures) [7]. (who.int)

In immune hemolytic anemia, your immune system destroys your red blood cells. (hoacny.com)

We describe a Japanese male neonatal case of G6PD deficiency presenting as severe, persistent indirect hyperbilirubinemia on day 2 and hemolytic anemia. (springeropen.com)

With inherited hemolytic anemias, one or more of the genes that control red blood cell production are faulty. (hoacny.com)
Certain forms of anemia are passed down through your genes, and infants may have it from birth. (webmd.com)

In select moderate or severe cases, medication administration is appropriate (see Treatment). (medscape.com)
In the most severe cases, or those cases that fail to respond to corticosteroids, other immunosuppressive agents may be utilized. (petplace.com)
However, LEE-negative STEC serotypes, including O104:H4 and O113:H21, can also cause outbreaks or severe cases ( 2 , 3 ). (cdc.gov)
Although most severe cases develop from intestinal tract infections, HUS cases related to urinary tract infections have been reported ( 4 ). (cdc.gov)

The most common symptom of anemia is fatigue (tiredness). (daviddarling.info)

The laboratory finding frequently observed is the moderate anemia with characteristics of regeneration (macrocytosis, reticulocytosis and polychromasia). (vin.com)

CASE REPORT A Japanese male term infant developed severe hemolytic anemia and metabolic acidosis in the early neonatal period. (bvsalud.org)
After age 1 month, he maintained good control of metabolic acidosis and hemolytic anemia . (bvsalud.org)
At the last follow-up at age 25 months, metabolic acidosis and hemolytic anemia were well controlled, but he had mild neurodevelopmental delay. (bvsalud.org)

Some genetic conditions that could contribute to this include sickle cell and some hemolytic anemias being passed down. (webmd.com)

If the anemia is severe or rapidly progressive, however, supportive care with transfusions of packed red blood cells may be warranted. (medscape.com)
Anemia is a condition in which the body does not have enough healthy red blood cells. (medlineplus.gov)
In hemolytic anemia, red blood cells in the blood are destroyed earlier than normal. (medlineplus.gov)
Complete blood count (CBC) should be performed on all dogs suspected of having anemia (decreased number of red blood cells), regardless of the cause. (petplace.com)
Hemolytic anemia is a rare form of anemia in which red blood cells ( erythrocytes ) are destroyed and removed from the bloodstream before their usual lifespan is up. (daviddarling.info)
In hemolytic anemia, the body breaks down and removes red blood cells faster than it can replace them. (daviddarling.info)
In some kinds of anemia, there are low amounts of all three types of blood cells. (daviddarling.info)
With acquired hemolytic anemias, your red blood cells may be normal. (hoacny.com)
Anemia is defined as a low number of red blood cells . (webmd.com)
With this type of anemia, your body may not create enough blood cells, or they may not work the way they should. (webmd.com)
When many red blood cells are destroyed, a person can develop hemolytic (hee-meh-LIH-tik) anemia . (kidshealth.org)
As the body makes new red blood cells, the anemia will improve. (kidshealth.org)
If red blood cells are destroyed faster than the fetus can produce new ones, the fetus can develop anemia. (msdmanuals.com)

In such cases, treatment consists of expectant management only. (medscape.com)
Mild hemolytic anemia may need no treatment at all. (daviddarling.info)
If you have an inherited form of hemolytic anemia, it's a lifelong condition that requires ongoing treatment. (daviddarling.info)
A child with severe anemia may need treatment in the hospital to get oxygen and fluids. (kidshealth.org)
Around the world, millions of people remain without access to malaria prevention and treatment, and most cases and deaths go unregistered and unreported. (who.int)

There are several reason's why a person would develop hemolytic anemia outside of the RBC. (nethealthbook.com)
Such people may develop hemolytic anemia. (tutorialspoint.com)

Anatomy12

Organisms18

Diseases70

Chemicals and Drugs89

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Psychiatry and Psychology1

Phenomena and Processes32

Disciplines and Occupations1

Information Science5

Named Groups1

Health Care11

Geographicals1

Autoimmune hemolytic anemias3

Jaundice3

Hemoglobin9

Donath-Landsteiner6

Types of hemolytic anemia4

Congenital3

Diagnosis10

Splenomegaly5

Symptoms13

Thrombocytopenia1

Antibody1

Hemolysis5

Uremic syndrome1

Clinical7

Hereditary5

AIHA4

Sickle cell a6

IMHA9

Spleen2

Chronic6

DLHA4

Splenectomy1

Disease3

Coombs1

Intravascular1

Methemoglobinemia2

Occurs1

Membrane1

Destruction5

Mild to severe1

20232

20221

Aplastic2

Bone2

Occupational4

Signs1

Diseases4

Crisis1

Disorders2

Immune system1

G6PD1

Genes2

Severe cases4

Tiredness1

Laboratory1

Metabolic3

Include1

Blood cells13

Treatment5

Develop2