Stereoselective halogenations of alkenes and alkynes can be conducted in room-temperature ionic liquids, 1-butyl-3-methylimidazolium hexafluorophosphate, 1-butyl-3-methylimidazolium tetrafluoroborate, 1-butyl-3-methylimidazolium bromide, and 1-butyl-3-methylimidazolium chloride as 'green' recyclable alternatives to chlorinated solvents. (organic-chemistry.org)
This is a [2+1] cycloaddition of a carbene to an alkyne or alkene (more specifically in the Dӧtz reaction a carbene coordinated to a metal carbonyl group) to produce substituted aromatic phenols. (wikipedia.org)
The reaction proceeds via a cascade of four subsequent pericyclic reactions (Scheme 3). (wikipedia.org)
For the synthesis of monoareno pentalenes, a carbopalladation cascade reaction between alkynes and gem-dibromoolefins was applied. (researchgate.net)
Moreover, the reaction can be combined with a subsequent intramolecular N-arylation to produce tetrahydroquinolines. (uniqsis.com)
A highly efficient visible-light-mediated photochemical [2 + 2] cycloaddition is coupled with an atom economic thermal cascade reaction in a continuous flow process. (uniqsis.com)
The application of high-temperature flow chemistry to the thermal cascade step allows for safe and reliable scale-up with short reaction times. (uniqsis.com)
alkyne-modified resins was accomplished by reaction of functional azides (octyl azide (1), (azidomethyl)benzene (2), 1-(6-azidohexyl) thymine (3), and 4-azido-N-(2,2,6,6-tetramethylpiperidin-4-yl)benzamide (4)) with Cu(I)Br and DIPEA as a base. (limkinase-signal.com)
Catalysts3
A sulfoxide reduction/C-S bond metathesis cascade between sulfoxides and alkyl bromides in an ionic liquid provides high-value sulfides without the use of any catalysts or bases. (organic-chemistry.org)
Knölker type iron complexes, used directly or generated in situ, are suitable catalysts for (de)hydrogenation reactions enabling the synthesis of carbonyl derivatives, amines and alcohols of industrial and academic interest. (eurekaselect.com)
We report herein an asymmetric cooperative process for the enantioselective 1,6-addition of β-ketoesters to in situ generated para-quinone methides with chiral Pd−aqua complexes as mixed Brønsted acid−base catalysts. (uni-leipzig.de)
Cycloaddition1
Upon addition of the alkyne a [2+2] cycloaddition occurs. (wikipedia.org)
Reactions2
When ketenes are formed in the presence of alkynes they proceed through pericyclic reactions to generate a substituted aromatic ring (Scheme 2). (wikipedia.org)
The in situ formation of reactive carbonyl electrophiles opens a wide array of possible subsequent reactions as illustrated in the following pages. (eurekaselect.com)
Formation1
In this study, we discovered a method for switching the cyclization mode from tetrahydrofuran to tetrahydropyran (THP) formation in epoxide-opening cascades of polyepoxides. (bvsalud.org)