• stroke
  • On September 30, 2004, Merck withdrew rofecoxib from the market because of concerns about increased risk of heart attack and stroke associated with long-term, high-dosage use. (wikipedia.org)
  • They were "stunned" by the result which showed there was no benefit from taking evacetrapib-434 participants who took Evacetrapib died from "cardiovascular disease, such as a heart attack or a stroke" and 444 participants who took a placebo died. (wikipedia.org)
  • Mitral stenosis poses a high risk of forming emboli which may travel to the brain and cause stroke. (wikipedia.org)
  • primary
  • The Primary Objective is to Evaluate the Effect of 4 g/Day AMR101 for Preventing the Occurrence of a First Major Cardiovascular Event. (clinicaltrials.gov)
  • This study confirms that primary preventive interventions should be based on assessment of global CVD risk rather than on individual risk factors and that existing cardiovascular conditions are a clear indication for instituting preventive measures, regardless of risk factor status. (acpjc.org)
  • Reduction
  • Prasugrel was approved for use in Europe in February 2009, and in the US in July 2009, for the reduction of thrombotic cardiovascular events (including stent thrombosis) in people with acute coronary syndrome (ACS) who are to be managed with percutaneous coronary intervention (PCI). (wikipedia.org)
  • Gender: Plasma concentrations are generally higher in women than in men, but there is no clinically significant difference in the extent of LDL reduction between men and women. (wikipedia.org)
  • females
  • 24 hyperlipidemic females followed diet low in saturated fat for a month, then they were randomly placed into a dietary portfolio low or high in monounsaturated fatty for another month. (wikipedia.org)
  • treatment
  • Evacetrapib evaluation for treatment of high-risk vascular disease was discontinued due to lack of efficacy, as had already happened in the past with two other CETP inhibitors (torcetrapib and dalcetrapib) due to increased deaths and little identifiable cardiovascular benefit (despite substantial increases in HDL). (wikipedia.org)
  • events
  • The Veterans Administration Cooperative Study ( 1 ) provided the first definitive evidence that antihypertensive drugs were efficacious in preventing major cardiovascular events. (acpjc.org)
  • enzyme
  • Thus, β-blockers, aspirin, and angiotensin-converting enzyme inhibitors are now standard in the armamentarium of cardiovascular preventive care. (acpjc.org)
  • concentrations
  • Soft drinks have been linked to NAFLD due to high concentrations of fructose, which may be present either in high-fructose corn syrup or, in similar quantities, as a metabolite of sucrose. (wikipedia.org)
  • The mean and median concentrations between different world populations show distinct particularities, the main being the two- to threefold higher Lp(a) plasma concentration of populations of African descent compared to Asian, Oceanic, or European populations. (wikipedia.org)