• Enrollment to RAFT-AF, which started in 2011, was halted in 2018 on its data-monitoring board's recommendation because of "perceived futility" after what had been a follow-up averaging less than 20 months, said principal investigator Anthony S. Tang, MD, Western University, London, Ontario, Canada, when presenting the trial during the online American College of Cardiology (ACC) 2021 Scientific Sessions. (medscape.com)
  • Journal of the American College of Cardiology, 82(9), 817-827. (ottawaheart.ca)
  • TRAUMATIC CORONARY ARTERY DISSECTION Abdelghany M, Elsheshtawy M, Attaran R , Kadura S, Mena-Hurtado C. TRAUMATIC CORONARY ARTERY DISSECTION Journal Of The American College Of Cardiology 2019, 73: 2411. (yale.edu)
  • UTERINE CERVICAL CANCER INVOLVING THE MYOCARDIUM AND PERICARDIUM Abdelghany M, Attaran R , Henry G, Mojibian H, Mena-Hurtado C. UTERINE CERVICAL CANCER INVOLVING THE MYOCARDIUM AND PERICARDIUM Journal Of The American College Of Cardiology 2019, 73: 2370. (yale.edu)
  • Journal of American College of Cardiology (JACC), the most prestigious journal of cardiology in US, paper published "Incidental Diagnosis of Cor-triatriatum in Two Elderly Patients. (yumaregional.org)
  • He was the recipient of an Established Investigator Award of the American Heart Association (AHA), he is a fellow of the American College of Cardiology, an Inaugural Fellow of the Council on Basic Cardiovascular Sciences of the AHA, and Dr. Kloner was elected to the American Society of Clinical Investigation. (hmri.org)
  • Dr. Kloner is a frequent lecturer at major scientific symposia including the Scientific Sessions of the American Heart Association, American College of Cardiology, and Transcatheter Cardiovascular Therapeutics Meetings, and he has lectured at most major academic medical centers in the United States. (hmri.org)
  • Ferrari has contributed scientific findings targeted at characterizing the molecular mechanisms of the ischemic and failing myocardium, dedicating himself to improving the clinical treatment of myocardial ischemia and heart failure, while placing a particular emphasis on interdisciplinary and collaborative studies throughout his career. (wikipedia.org)
  • Thallium-201 with redistribution is a classical isotopic test used to detect viable myocardium in patients with ischemic heart disease and depressed ventricular function. (escardio.org)
  • This finding shows that ischemic but noninfarcted myocardium can exist in a state of hibernation without cell death. (medscape.com)
  • We conclude the following: (1) During transmural ischemia percent systolic thickening is markedly impaired in nonischemic myocardium immediately adjacent to the ischemic region, and is impaired to a lesser degree in regions located relatively far from the ischemic border. (johnshopkins.edu)
  • 2) During subendocardial ischemia function ceases in the ischemic region and functional impairment of nonischemic myocardium is restricted to immediately adjacent regions. (johnshopkins.edu)
  • 4) Mechanical tethering of nonischemic myocardium adjacent to ischemic regions, secondary to changes in left ventricular shape during contraction, may contribute to the impairment of systolic thickening in adjacent regions during transmural ischemia. (johnshopkins.edu)
  • At the same time restoring the patency of the coronary vessels and providing the ischemic myocardium with blood can cause additional tissue damage. (eurekaselect.com)
  • A key element of ischemic and reperfusion injury and major determinant of the evolution of damage in the injured myocardium is the inflammatory response. (eurekaselect.com)
  • He performed some of the first studies on and helped define the concepts of no reflow in the heart (at Northwestern University), stunned myocardium, remote ischemic preconditioning, and triggers of cardiovascular events. (hmri.org)
  • Stunned myocardium is myocardium that suffers transient reversible myocardial contractile dysfunction that is caused by acute ischemia during which the blood supply is almost completely restored by reperfusion, with no metabolic deterioration. (medscape.com)
  • The term hibernating myocardium is also used to indicate chronic myocardial contractile dysfunction due to ischemia, in which there is reduced coronary blood flow at rest and increased myocardial demand results in impaired contractility. (medscape.com)
  • Schematic representation of infarction (cell death), chronic ischemia with contractile dysfunction (hibernating myocardium), and transient ischemia (stunned myocardium) with restored blood flow with transient contractile dysfunction. (medscape.com)
  • Clinically, discerning the etiology of depressed myocardial contractile function is difficult, whether due to stunned myocardium, silent ischemia, or hibernating myocardium. (medscape.com)
  • Progenitor cell therapy is being investigated for the treatment of damaged myocardium resulting from acute or chronic cardiac ischemia and for refractory angina. (southcarolinablues.com)
  • Hibernating myocardium: an incomplete adaptation to ischemia. (smw.ch)
  • Revascularization of chronic hibernating myocardium stimulates myocyte proliferation and partially reverses chronic adaptations to ischemia. (smw.ch)
  • To study the regional function of nonischemic myocardium after the onset of regional ischemia, graded circumflex coronary arterial stenosis was induced in 18 open-chest anesthetized dogs. (johnshopkins.edu)
  • CABG may be performed as an emergency procedure in the context of an ST-segment elevation MI (STEMI) in cases where it has not been possible to perform percutaneous coronary intervention (PCI) or where PCI has failed and there is persistent pain and ischemia threatening a significant area of myocardium despite medical therapy. (medscape.com)
  • The vascular territories of the left ventricular myocardium are divided into 17 segments and illustrated by the cardiac segmentation model of the American Heart Association (AHA) 6,7 . (radiopaedia.org)
  • Delay in revascularization is associated with increased mortality rate in patients with severe left ventricular dysfunction and viable myocardium on fluorine 18-fluorodeoxyglucose positron emission tomography imaging. (smw.ch)
  • The myocardium defines the middle layer of the cardiac wall between the endocardium and the pericardium and forms the muscular part of the heart . (radiopaedia.org)
  • The myocardium represents the middle layer of the cardiac wall. (radiopaedia.org)
  • Venous drainage of the myocardium is provided via the cardiac veins and the coronary sinus as well as the Thebesian veins 8 . (radiopaedia.org)
  • Cardiac lymphatic flow passes from the endocardium through the myocardium to the epicardium where small lymphatic vessels drain into larger collecting vessels. (radiopaedia.org)
  • The myocardium is innervated by the cardiac conduction system . (radiopaedia.org)
  • After general medical training he specialised in cardiac medicine learning both noninvasive and invasive techniques, and for the last 20 years he has practised noninvasive cardiac imaging, with major clinical and research interests in nuclear cardiology, magnetic resonance and in cardiovascular X-ray computed tomography. (imperial.ac.uk)
  • His current research interests include the assessment of myocardial perfusion using pharmacological stress, the characterisation of hibernating myocardium, and the cost-effectiveness of cardiac imaging techniques. (imperial.ac.uk)
  • Associate Professor Nathan Better is a clinical cardiologist specialising in nuclear cardiology and cardiac CT. (cabrini.com.au)
  • His research interests include the role of cardiac imaging in diagnosis and prognosis and radiation safety, cardiac CT and nuclear cardiology and has published over 70 peer-reviewed articles. (cabrini.com.au)
  • Cardiac amyloidosis (CA) is defined by the presence of extracellular amyloid deposition within the myocardium of the whole heart, leading to biventricular wall thickening with impaired relaxation and the loss of ventricular elasticity [ 1 ]. (hindawi.com)
  • Myocarditis Myocarditis is inflammation of the myocardium with necrosis of cardiac myocytes. (msdmanuals.com)
  • Evidence of myocarditis and eosinophilic infiltration of the myocardium, which is obtained through invasive biopsy or cardiac MRI, establishes the diagnosis. (medscape.com)
  • Identification of viable and hibernating myocardium allows for a better selection of patients who need revascularisation. (escardio.org)
  • Consequently, the noninvasive determination of viable myocardium is becoming increasingly important. (escardio.org)
  • Although DSE and Thallium-201 with redistribution have been validated for the diagnosis of viable myocardium, they frequently yield conflicting results. (escardio.org)
  • When both DSE and Thallium-201 are performed in the same patient, discordant results are often obtained In fact, in comparative studies where both techniques have been used prior to revascularisation procedures, the sensitivity, specificity and predictive value for the detection of viable myocardium have been found to differ. (escardio.org)
  • 1 IVUS has been "corrected" for vessel size, but IVUS has not been able to factor in the amount of subtended viable myocardium. (acc.org)
  • The histology of viable and hibernating myocardium in relation to imaging characteristics. (smw.ch)
  • The "holy grail" of modern interventional cardiology is the salvage of viable myocardial tissue in the distribution of an acutely occluded coronary artery. (eurekaselect.com)
  • Basic Research in Cardiology , 105(2), pp. 279-287. (gla.ac.uk)
  • He is on the editorial boards of American Journal of Cardiology, Basic Research in Cardiology, International Journal of Impotence Research, Journal of Cardiovascular Pharmacology and Therapeutics, Regenerative Medicine, and Life Sciences. (hmri.org)
  • Correction to: ASNC imaging guidelines/SNMMI procedure standard for positron emission tomography (PET) nuclear cardiology procedures. (ottawaheart.ca)
  • Hibernating myocardium: diagnosis and patient outcomes. (smw.ch)
  • Cardiology is the diagnosis and take care of human or perhaps animal hearts In the concentrate of the Cardiology, the heart has its own different physiological features which include ventricles, atria and regulators. (e-vocable.com)
  • Roberto Ferrari (born 10 June 1950) is an Italian cardiologist who currently holds the position of Emeritus Professor at the University of Ferrara, where besides he was the chair of the Cardiology in the School of Medicine until the 2019-2020 academic year. (wikipedia.org)
  • Edward Araujo JĂșnior, Nathalie Jeanne M. Bravo-Valenzuela, Alberto Borges Peixoto , " Perinatal Cardiology-Part 2 ", Bentham Science Publishers (2020). (benthamscience.com)
  • Cardiology 2020 10 0. (cdc.gov)
  • Dr. Joseph Hill, Chief of the Division of Cardiology at the University of Texas Southwestern Medical Center, talks to host Dr. Matthew Sorrentino about the changes that occur in the myocardium when the heart begins to fail. (reachmd.com)
  • In hibernating myocardium, contractile function can be partially or totally restored by improving coronary blood flow or by reducing oxygen demand of the myocardium. (medscape.com)
  • Rahimtoola suggested that hibernating myocardium is characterized by a state of persistently impaired myocardial and LV function at rest due to reduced coronary blood flow that can be partially or completely restored to normal by improving blood flow or by reducing oxygen demand (see the image below). (medscape.com)
  • The hibernating myocardium. (smw.ch)
  • Temporal and spatial variations in structural protein expression during the progression from stunned to hibernating myocardium. (smw.ch)
  • Sensitivity, specificity, and predictive accuracies of various noninvasive techniques for detecting hibernating myocardium. (smw.ch)
  • As a leading reference on pediatric cardiology and congenital heart disease , Anderson's Pediatric Cardiology provides exhaustive coverage of potential pediatric cardiovascular anomalies, potential sequelae related to these anomalies, comorbidities and neurodevelopmental problems, and current methods for management and treatment. (bookbaz.ir)
  • This noninvasive test can identify and quantify areas of inadequate blood supply within the myocardium (heart muscle), detect scaring of the myocardium, and assess the heart's pumping function. (imaginis.com)
  • Transthyretin amyloid cardiomyopathy (ATTR-CM), of which there are 2 types (hereditary/variant [ATTRv-CM] and wild-type [ATTRwt-CM]), is caused by deposition of amyloid in the myocardium. (medpagetoday.com)
  • The arterial supply of the myocardium is provided by the coronary arteries . (radiopaedia.org)
  • BACKGROUND: In the medical literature, several cases of Tako-tsubo cardiomyopathy (TTC) with coronary artery disease (CAD) have been reported, and in clinical practice, several typical TTC cases show relevant stenoses of the coronary arteries spatially unrelated to the dysfunctional myocardium. (who.int)
  • 50%) coronary stenosis not supplying the dysfunctional myocardium, whereas 407 patients (90.4%) had irrelevant stenosis or angiographically normal coronary arteries. (who.int)
  • Low-dose dobutamine infusion is able to demonstrate the contractile reserve of myocardium as it shows an improved contractility following infusion of this positive inotropic drug. (escardio.org)
  • The inner border merges with the subendocardial tissue layer, which contains collagen, elastic fibers small blood vessels and nerves as well as the Purkinje fibers and connects the extracellular matrix of the myocardium to the endocardium 4 . (radiopaedia.org)
  • The myocardium consists of cardiomyocytes grouped in strands also known as myofibres and the surrounding extracellular matrix with endomysial and perimysial components. (radiopaedia.org)
  • Restrictive cardiomyopathy (RCM) is a rare disease of the myocardium and is the least common of the 3 clinically recognized and described cardiomyopathies. (medscape.com)
  • [ 1 , 4 ] The disease creates increased stiffness of the myocardium, which causes pressure within the ventricles to rise precipitously with small increases in volume. (medscape.com)
  • 1 Treatment with progenitor cells (i.e., stem cells) offers potential benefits beyond those of standard medical care, including the potential for repair and/or regeneration of damaged myocardium. (southcarolinablues.com)
  • His contributions to the field of cardiology include a lengthy publication list of several books, over 800 published peer-reviewed papers, citation numbers nearing 50 000, and an H-index that is close to 90. (wikipedia.org)
  • For more insight and commentary on these stories, subscribe to the This Week in Cardiology podcast , download the Medscape app or subscribe on Apple Podcasts , Spotify , or your preferred podcast provider. (medscape.com)
  • Additional training included clinical and research fellowships in medicine and cardiology (with Eugene Braunwald, MD, and Peter Maroko, MD) at Harvard Medical School and Brigham and Women's Hospital. (hmri.org)
  • Background The pathophysiology and prognostic significance of remote myocardium in the natural history of STEMI is uncertain. (dundee.ac.uk)
  • Professor Ferrari's fundamental involvements in medical research incorporate various aspects of basic study, pathophysiology and clinical investigation that have made him a prominent figure in the field of cardiology, with him being professionally recognized and interviewed by several top high-impact scientific journals, such as: The Lancet, the European Heart Journal and Circulation. (wikipedia.org)
  • The title is " Bringing the Credibility Revolution to Observational Research in Cardiology . (medscape.com)
  • Nathan is committed to clinical research and medical education, and is the Chairman of the Cabrini Cardiology Research Group, and Director of Physician Training at Cabrini. (cabrini.com.au)
  • Dive into the research topics of 'Beyond the myocardium? (uthscsa.edu)
  • While lots is known regarding the healthful heart, Cardiology usually research diseased hearts. (e-vocable.com)
  • Regenerative medicine embodies tissue engineering and artificial organs and touches on essentially all medical specialties from cardiology through obstet-rics, cancer, trauma and others. (brown.edu)
  • The techniques will include generation of models featuring tissue-specific disruption of selected genes using Cre-loxP systems (in adipocytes, muscle, endothelium, pericytes and myocardium as required). (lu.se)
  • In 2000, Professor Ferrari was appointed to the position of Full Professor in Cardiology as well as the Director of the Cardiovascular Centre of the University of Ferrara and Director of Cardiology at the St. Anna University Hospital of Ferrara. (wikipedia.org)
  • His academic career path development follows his initial appointment to the position of associate professor in Cardiology at the University of Brescia in 1987 and then at the University of Ferrara in 1998. (wikipedia.org)
  • Thus, when the stenotic artery does not supply the dysfunctional myocardium or when the extent of dysfunctional myocardium is wider than the territory of distribution supplied by a single stenotic coronary artery, the presence of angiographically relevant CAD should not be considered an exclusion criterion for TTC. (who.int)