• myocardial
  • This commonly occurs as a result of chest trauma (both blunt and penetrating), but can also be caused by myocardial rupture, cancer, uremia, pericarditis, or cardiac surgery, and rarely occurs during retrograde aortic dissection, or while the person is taking anticoagulant therapy. (wikipedia.org)
  • Causes
  • Increased microtubule density, for which microtubule stabilization is one potential mechanism, causes contractile dysfunction in cardiac hypertrophy. (rupress.org)
  • This causes the development of obstructive shock, which if left untreated may lead to cardiac arrest (often presenting as pulseless electrical activity). (wikipedia.org)
  • pressure
  • Thus, microtubule stabilization, likely facilitated by binding of a microtubule-associated protein, may be a mechanism for the increased microtubule density characteristic of pressure overload cardiac hypertrophy. (rupress.org)
  • suggesting that an extending force, such as that exerted on the cardiocyte by cardiac pressure loading, could rapidly shift the dynamic equilibrium between free and polymerized tubulin toward the polymerized form. (rupress.org)
  • disease
  • As a result, the risk-to-benefit ratio still favors performing this procedure as a part of the evaluation of potentially fatal or lifestyle-limiting cardiac disease. (uptodate.com)