Carcinoma cell proliferation neoplasms plasma cell. Medical search. Frequent questions

Gastrin and its derivates have been reported to regulate epithelial cell proliferation, migration, and differentiation. (tum.de)
India ink is often used as a phagocytosis labeling agent or a cell differentiation tracer because CB is easily administered, is relatively nontoxic, and is easily observed in cells that have taken it up. (nanomedicine.com)
LPA acts as an autocrine/paracrine messenger through at least six G protein-coupled receptors (GPCRs), known as LPA 1-6 , to induce various cellular processes including wound healing, differentiation, proliferation, migration, and survival. (hindawi.com)
Lymphoplasmacytic lymphoma (LPL) is a neoplasm of mature B-cells exhibiting some plasmacytic differentiation. (hematology.org)
However, the vast majority of human cancers are characterized by a multiple-step process involving many genetic abnormalities, each of which contributes to the loss of control of cell proliferation and differentiation and the acquisition of capabilities, such as tissue invasion, the ability to metastasize, and angiogenesis. (mhmedical.com)
Thrombopoiesis takes place primarily in the bone marrow through a series of cell differentiation and is influenced by several cytokines. (lecturio.com)
Mice homozygous for a null allele show embryonic lethality, severe growth retardation, reduced neuron proliferation, increased neuron apoptosis, impaired neuron differentiation, small hearts, abnormal cardiac looping and, in some cases, incomplete embryonic turning and neural tube closure defects. (jax.org)
Its prominent properties are A lack of cell differentiation Local invasion of adjoining tissue Metastasis, which is spread to distant sites through. (msdmanuals.com)

Flow cytometry was used to detect cell cycle and apoptosis. (besjournal.com)
Our results indicated that AST inhibits cell proliferation through phase-specific cell cycle arrest and caspase-dependent apoptosis. (spandidos-publications.com)
These abnormalities result in significant alterations in gene expression related to cell proliferation, apoptosis, migration and immune signaling pathways. (spandidos-publications.com)
recruits CD8+ T cells, granulocytes, and macrophages to the infection area and induces the release of TNF-related apoptosis-inducing ligand (TRAIL) from neutrophils. (metabiom.org)
Once in the tumor, S. typhimurium continues to proliferate and directly kills cancer cells by triggering of apoptosis, necrosis, and cell rupture. (metabiom.org)
Most CD8 cells are directed to lytic antigens initially, and these cells rapidly undergo apoptosis ( 7 ). (frontiersin.org)
Inhibition of ezrin synergizes with lapatinib in a PKC-dependent fashion to inhibit proliferation and promote apoptosis in HER2-positive breast cancer cells. (korea.ac.kr)

CONTEXT: Gastric neuroendocrine tumors are rare neoplasms that originate from gastric enterochromaffin-like (ECL) cells in the oxyntic mucosa. (tum.de)
OBJECTIVE: In this study we investigated the histopathological and molecular findings in the gastrointestinal wall of a patient with multiple endocrine neoplasia type 1 with malignant duodenal gastrinoma and multiple gastric ECL cell tumors, who additionally developed a signet-ring cell carcinoma of the stomach. (tum.de)
RESULTS: Immunohistochemical studies of gastric ECL cell tumors showed a largely diminished E-cadherin expression in comparison to gastric surface mucosa cells and a loss of E-cadherin expression in the cells of the signet-ring carcinoma. (tum.de)
Most benign spindle cell tumors of the urinary bladder are an inflammatory myofibroblastic tumor (IMT). (medscape.com)
[ 11 ] The oldest large series of 38 spindle cell tumors in the urinary bladder included 17 pseudotumors, 4 postoperative spindle cell nodules (PSCNs), and 13 sarcomas. (medscape.com)
Proliferating Trichilemmal Tumors (PTTs) are neoplasms derived from the outer root sheath of the hair follicle. (scitechnol.com)
However, because a wide variety of genetic and epigenetic changes can occur in different cells within malignant tumors over time, most cancers are characterized by marked heterogeneity in the populations of cells. (mhmedical.com)
Here, we demonstrate that the endoplasmic reticulum stress sensor inositol-requiring enzyme 1 (IRE1α) and its substrate transcription factor X-box-binding protein 1 (XBP1) drive NK cell responses against viral infection and tumors in vivo. (cancerindex.org)
Male rats had dose-related and statistically significant increase of benign Leydig cell tumors. (drugcentral.org)
There were no statistically significant differences from controls in the incidence of liver tumors, but the doses tested were lower than those shown to be carcinogenic with other fibrates.Electron microscopy studies have demonstrated florid hepatic peroxisome proliferation following gemfibrozil administration to the male rat. (drugcentral.org)
Stromal tumors of the ovary include germ-cell tumors, sex-cord stromal tumors, and other more rare types. (medscape.com)
EPO-secreting tumors EPO-secreting tumors Polycythemia Vera , such as renal cell carcinoma Renal cell carcinoma Renal cell carcinoma (RCC) is a tumor that arises from the lining of the renal tubular system within the renal cortex. (lecturio.com)
destroy tumors by secreting exotoxins that damage the membrane structures of cancer cells and enter cells to disrupt essential cellular functions. (metabiom.org)
target tumors through the intracellular infection of tumor-infiltrating myeloid-derived suppressor cells (MDSCs), which migrate to the immunosuppressive TME. (metabiom.org)
#Salmonella typhimurium ] - S. typhimurium, an intracellular pathogen, is chemoattracted to, and retained in, tumors due to the presence of metabolites produced by quiescent cancer cells within the TME (Tumor Micro envirounment). (metabiom.org)
We found ezrin to be expressed at low levels at the apical surface of normal mammary epithelial cells, but its expression is up-regulated and correlates with HER2 expression in hyperplasia and tumors in murine mammary tumor virus-Neu mice, in human HER2-positive breast cancer cell lines, and in ductal carcinoma in situ and invasive breast cancers from human patients. (korea.ac.kr)

Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
Recent studies show that ClC-3 plays an active and vital role in accelerating neoplasm metastasis and may be a prognostic biomarker of tumour dissemination [ 11 ]. (biomedcentral.com)
Additionally, the expression and activity of matrix metalloproteinases (MMPs) are increased in almost every type of human cancer, which may be associated with cell invasion, metastasis and angiogenesis. (spandidos-publications.com)
MMPs have been implicated in these processes and a previous study has suggested that the plasma level of MMP-2 and MMP-9 may be viewed as a non-invasive indicator of invasiveness and metastasis in colon cancer ( 3 ). (spandidos-publications.com)
AXL significantly promotes tumour cell migration, invasion and metastasis, as well as angiogenesis. (cancerindex.org)

Multiple myeloma (MM) is a neoplastic, monoclonal proliferation of terminally differentiated plasma cells. (thejh.org)
Cancers are named based on their origin: those derived from epithelial tissue are called carcinomas , those derived from mesenchymal tissues are sarcomas , and those derived from hematopoietic tissue are leukemias , lymphomas , and plasma cell dyscrasias (including multiple myeloma ). (mhmedical.com)
Multiple myeloma (also known as MM , myeloma , plasma cell myeloma , or as Kahler's disease after Otto Kahler) is a presently incurable hematological malignancy of plasma cells, the cells of the immune system that produce antibodies. (the-medical-dictionary.com)
Multiple myeloma, a rare malignancy of plasma cells, was first described in 1950 as an abnormal production of immunoglobulins. (the-medical-dictionary.com)
Among 27 cancer types, low HDL cholesterol and/or apolipoprotein A1 were associated with increased risk of multiple myeloma, myeloproliferative neoplasm, non-Hodgkin lymphoma, breast cancer, lung cancer, and nervous system cancer. (biomedcentral.com)
Multiple Myeloma Multiple myeloma is a cancer of plasma cells that produce monoclonal immunoglobulin and invade and destroy adjacent bone tissue. (msdmanuals.com)

Additional findings are: a raised calcium (when myeloma cells are breaking down bone, releasing calcium into the bloodstream) and decreased renal function, which may be due to paraprotein deposition in the kidney). (the-medical-dictionary.com)
Renal cell carcinoma is responsible for 80%-85% of all primary renal neoplasms. (lecturio.com)
Clear cell renal cell carcinoma (ccRCC) is the seventh most frequently diagnosed tumor in adults in Europe and represents approximately 2.5% of cancer deaths. (cancerindex.org)
The molecular biology underlying renal cell carcinoma (RCC) development and progression has been a key milestone in the management of this type of tumor. (cancerindex.org)
The relationship between blood pressure and risk of renal cell carcinoma. (who.int)
Epidemiology of Renal Cell Carcinoma: 2022 Update. (who.int)
Mycotoxin Exposure and Renal Cell Carcinoma Risk: An Association Study in the EPIC European Cohort. (who.int)
Biomarkers of the transsulfuration pathway and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. (who.int)

Subsequent studies revealed that EBV caused a number of different human malignancies, such as nasopharyngeal carcinoma (NPC), Hodgkin's lymphoma, extranodal NK/T-cell lymphoma, nasal type and lymphoproliferative disorders of immunocompromised hosts ( 2 ). (spandidos-publications.com)
whole-body (18)f-fdg pet/ct for m staging in the patient with newly diagnosed nasopharyngeal carcinoma: who needs? (liverpool.ac.uk)
although whole-body fluorine-18 fluorodeoxyglucose ((18)f-fdg) positron emission tomography (pet)/computed tomography (ct) ((18)f-fdg pet/ct) is commonly used for m staging of newly diagnosed nasopharyngeal carcinoma (npc), some patients may not benefit from this procedure. (liverpool.ac.uk)

The most common type of cervical cancer is squamous cell carcinoma (SCC), which develops from low-squamous intraepithelial lesions (LSIL) and high-squamous intraepithelial lesions (HSIL). (biomedcentral.com)

EBVaGC is defined by monoclonal proliferation of carcinoma cells with latent EBV infection, as demonstrated by EBV-encoded small RNA (EBER) in situ hybridization. (spandidos-publications.com)

Once it affects these areas degeneration starts targeting the myelin sheath (Nerves that insulates the layers of cells) and causes a string of patches of sclerotic tissues. (jagomart.net)
Methods The miR-224-5p expression in CRC patient tissues and cell-derived exosomes was measured by laser capture microdissection and qRT-PCR, respectively. (besjournal.com)
The tumor size and the number of proliferating cells were reduced in the tumor tissues obtained from the formononetin-treated group. (spandidos-publications.com)
In obese humans, adipocyte-secreted CCL20 may contribute to the deposition of Compact disc4+ helper and Compact disc8+ cytotoxic T lymphocytes within adipose tissues, possibly via connections with CCR6 which was upregulated on T cells in obese adipose tissues (100). (exposed-skin-care.net)
However, the main element substances that mediate T cell infiltration into adipose tissues in maturing remain to become discovered. (exposed-skin-care.net)
Activation of Typical T Cells in Adipose Tissues Compact disc4+ Purpureaside C T Cell Activation TCRs recognize the current presence of a particular antigen by binding to brief peptide sequences in the antigen that's shown on APCs. (exposed-skin-care.net)
further defined that mostly huge adipocytes from obese adipose tissues exhibited an increased expression degree of MHCII substances and acted as APCs to activate Compact disc4+ T cells to secrete IFN- (103). (exposed-skin-care.net)
These patients are unable to control EBV infection and have infiltration of tissues by EBV positive T, NK, or less often B cells. (frontiersin.org)
genic models are inadequate for number of activated CD8-positive T LMP1 was strongly expressed in the understanding the cancer etiology in cells increased considerably in the lymphoma tissues but was hardly the context of natural viral infection. (who.int)

Clear cell acanthoma (also known as Acanthome cellules claires of Degos and Civatte, Degos acanthoma, and Pale cell acanthoma) is a benign clinical and histological lesion initially described as neoplastic, which some authors now regard as a reactive dermatosis. (wikipedia.org)
A neoplasm is benign when it grows in an unregulated fashion without tissue invasion. (mhmedical.com)
The incidence of benign liver nodules and liver carcinomas was significantly increased in high dose male rats. (drugcentral.org)
The higher dose female rats had significant increase in the combined incidence of benign and malignant liver neoplasms.Long-term studies have been conducted in mice at 0.1 and 0.7 times the human exposure (based on AUC). (drugcentral.org)
PC-ALCL is one of the primary cutaneous CD30 + T-cell lymphoproliferative disorders, a wide spectrum of disease, with lymphomatoid papulosis (LyP) at the benign end of the spectrum and PC-ALCL at the malignant end. (medscape.com)

In the present study, we aimed to further examine the potential of formononetin in controlling angiogenesis and tumor cell invasiveness in human colon cancer cells and tumor xenografts. (spandidos-publications.com)
We also discovered that the invasiveness of metastatic colon cancer cells was alleviated following drug treatment. (spandidos-publications.com)

Immunohistochemistry was performed to identify T or B cell origin, using anti-CD3 polyclonal antibody (Dako) and anti-CD79a monoclonal antibody (Dako), respectively. (vin.com)

Epithelioid angiosarcoma is a rare malignant neoplasm found in vascular endothelial cells. (bvsalud.org)
Epithelioid angiosarcoma (EA) is a rare variant of angiosarcoma, which is characterized by a high-grade malignant neoplasm, which consists of an atypical, multilayered, or solid endothelial proliferation and vasoformative architecture, presenting necrosis and an area of hemorrhage 1-5 . (bvsalud.org)

Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by the overproduction of RBCs. (lecturio.com)

The result is a lymphoma comprising of small B-lymphocytes, plasmacytoid B-cells with more abundant cytoplasm, as well as clonal plasma cells. (hematology.org)
Polycythemia vera (PV) is a clonal disorder resulting from neoplastic transformation of hematopoietic stem cells, while secondary polycythemia (SP) is a disease characterized by increased absolute red blood cell mass caused by stimulation of red blood cell production. (nature.com)
The uniformity of the numbers of terminal repeats (TRs) among EBV positive carcinoma cells reflects the clonal origin of a tumor and suggests that EBV is a causative virus for gastric carcinoma ( 6 ). (spandidos-publications.com)
A large clonal or oligoclonal expansion of CD8 cells is observed during infectious mononucleosis ( 6 ). (frontiersin.org)
Epstein-Barr virus (EBV) infection has been prominently associated with HPS, with clonal proliferation and the hyperactivation of EBV-infected T cells. (biomedcentral.com)

[ 9 ] Among the 38 cases, the mean age of patients was 38 years for pseudotumor (age range, 15-74 years), 65 years for postoperative spindle cell nodule, 51 years for sarcoma, and 76 years for carcinoma. (medscape.com)
In a large series of 38 cases, after review and immunohistochemical workup, 17 patients had inflammatory pseudotumor (myofibroblastic tumor), 4 patients had postoperative spindle cell nodule, and 1 patient had leiomyoma. (medscape.com)
Pre-treatment biopsy demonstrates bland spindle cell proliferation and irregular bony trabeculae resembling fibrous dysplasia. (medscape.com)

Subsequent study using multiple human cancer cell lines, including those of the colon, stomach and liver, further indicated the universal growth-inhibitory and pro-apoptotic effects of AST. (spandidos-publications.com)
The incidence of liver carcinomas increased also in low dose males, but this increase was not statistically significant (p=0.1). (drugcentral.org)
Peroxisome proliferation has been shown to occur in humans with either of two other drugs of the fibrate class when liver biopsies were compared before and after treatment in the same individual.Administration of approximately times the human dose (based on surface area) to male rats for 10 weeks resulted in dose-related decrease of fertility. (drugcentral.org)
Hemophagocytic syndrome (HPS) is clinically defined as a combination of fever, liver dysfunction, coagulation abnormalities, pancytopenia, progressive macrophage proliferation throughout the reticuloendothelial system, and cytokine over-production, and may be primary or secondary to infectious, auto-immune, and tumoral diseases. (biomedcentral.com)

Differentiating between low-grade lymphoma and reactive lymphocytes is often difficult by morphology alone as reactive lymphoid cells may acquire activation morphology from being exposed to different cytokines within the body fluid. (cytojournal.com)
In large cell lymphoma and leukemia cells involvement of body fluid this concept becomes less challenging. (cytojournal.com)
Large cell lymphoma and leukemia cells tend to have large size nuclei, less mature chromatin, and visible nucleoli with and without cytoplasmic vacuoles. (cytojournal.com)
EBV was the first virus to be associated with human malignancy, which was discovered from a Burkitt's lymphoma cell line in 1964 ( 1 ). (spandidos-publications.com)
Persistent infection with H. pylori induces atrophic gastritis and intestinal metaplasia, and subsequently leads to gastric malignancies including gastric carcinoma and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). (spandidos-publications.com)
epstein-barr virus (ebv) is a human γ-herpesvirus associated with cancer, including burkitt lymphoma, nasopharyngeal, and gastric carcinoma. (liverpool.ac.uk)
plasma epstein-barr virus dna for pediatric burkitt lymphoma diagnosis, prognosis and response assessment in malawi. (liverpool.ac.uk)
novel mutations in sh2d1a gene in x-linked lymphoproliferative syndrome, diagnosed after b-cell non-hodgkin lymphoma. (liverpool.ac.uk)
x-linked lymphoproliferative disease type i (xlp i) is caused by mutations in the sh2d1a gene and characterized mainly by hypogammaglobulinemia and abnormal response to epstein-barr virus with a high predisposition to b-cell non-hodgkin lymphoma development. (liverpool.ac.uk)
Animal models for human tumour mental animals is not easy to answer does induce adult T-cell leukaemia/ viruses that make use of animal virus- for these agents, because cancer bi- lymphoma (ATLL), albeit in monkeys es are scarce. (who.int)
This ulcerated nodule of localized primary cutaneous CD30+ anaplastic large cell lymphoma is relatively nonspecific in appearance. (medscape.com)

A 70-year-old man with a history of urothelial carcinoma presents with fatigue. (hematology.org)
ATR Inhibition in Advanced Urothelial Carcinoma. (ucdavis.edu)

For instance, mice are able to reconstitute most lymphomas in monkeys and humans woodchuck hepatitis virus induces major components of the human provides strong support for a direct hepatocellular carcinoma (HCC) haematolymphoid system including oncogenic role of EBV in vivo. (who.int)

Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
Edema builds up abnormal and excessive fluids that cause serious actions to the tissue cells. (jagomart.net)
Many cancers go through recognizable steps of progressively more abnormal phenotypes: hyperplasia, to adenoma, to dysplasia, to carcinoma in situ, to invasive cancer with the ability to metastasize ( Table 26-1 ) . (mhmedical.com)

indicated that ATMs colocalized with T cells in lymphoid clusters within adipose tissue and may act as APCs, which express high levels of MHCII and also costimulatory molecules and process and present antigens to induce CD4+ T-cell proliferation and activation in adipose tissue of obese mice (29, 68, 105). (exposed-skin-care.net)
involves the combination of the direct killing of cancer cells by #Listeria infection and cytotoxic T cell response toward #Listeria antigens. (metabiom.org)
Sixty percent of cases express 1 or more T-cell antigens (CD3 + , CD43, or CD45RO). (medscape.com)

Previously, our studies found that ClC-3 plays a key role in ectopic endometrial cell migration and invasion [ 5 ]. (biomedcentral.com)
The combination of CD38 and CD31 plays an important role in cell migration and receptor-mediated adhesion. (cusabio.com)
studies indicated that RANTES is Purpureaside C an adipokine that can be produced by adipocytes and takes on an important part in T cell migration, suggesting a potential part of the RANTES/CCR5 axis in adipose T cell build up in obesity (24). (exposed-skin-care.net)
This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. (cancerindex.org)
A novel human anti-AXL monoclonal antibody attenuates tumour cell migration. (cancerindex.org)
Recent studies have revealed that AXL contributes to leukaemic phenotypes through activation of oncogenic signalling pathways that lead to increased cell migration and proliferation. (cancerindex.org)

The incidence of hepatocellular adenoma or carcinoma (combined) in 80 mg/kg females was significantly increased. (nih.gov)
The distinction between Hürthle cell adenoma and carcinoma is based on presence of capsular or vascular invasion, or both. (cap.org)

Cancers are characterized by unregulated cell division, avoidance of cell death, tissue invasion, and the ability to metastasize. (mhmedical.com)
Cancers nearly always arise as a consequence of genetic alterations, the vast majority of which begin in a single cell and therefore are monoclonal in origin. (mhmedical.com)
This heterogeneity significantly complicates the treatment of most cancers because it is likely that there are subsets of cells that will be resistant to therapy and will therefore survive and proliferate even if the majority of cells are killed. (mhmedical.com)
A few cancers appear to, at least initially, be primarily driven by an alteration in a dominant gene that produces uncontrolled cell proliferation. (mhmedical.com)
These findings suggest that formononetin inhibits angiogenesis and tumor cell invasion, and thus support its use in the treatment of advanced and metastatic colon cancers. (spandidos-publications.com)
that is histopathological y very simi- T cel s, B cel s, natural kil er cel s, LMP1 of EBV can transform ro- lar to that caused by hepatitis B vi- macrophages, and dendritic cells, dent fibroblasts and is expressed rus (HBV) in humans, but it does so and this humanized mouse model in most of the human cancers as- through a different mechanism. (who.int)

LAT1 was pharmacologically blocked by JPH203 in human ATC and papillary thyroid cancer (PTC) cell lines. (unibe.ch)
These neoplasms can show follicular, trabecular, solid, or papillary growth patterns with occasional nuclear grooves or nuclear pseudoinclusions. (cap.org)
An enlarged ovary with a papillary serous carcinoma on the surface. (medscape.com)

Primary lesions include epithelial ovarian carcinoma (70% of all ovarian malignancies). (medscape.com)

1) It accounts for approximately 10 to 15% of all hematologic malignancies, 1% of all malignant neoplasms in whites and 2% in blacks, and 2% of deaths from all malignancies. (the-medical-dictionary.com)

Furthermore, the high expression levels of ClC-3 was significantly correlated to poor survival in cervical carcinoma patients (Log-rank test, p = 0.046). (biomedcentral.com)
Unrelated cord blood transplantation vs. HLA-matched sibling transplantation for adults with B-cell acute lymphoblastic leukemia in complete remission: superior OS for patients with long-term survival. (ucdavis.edu)
Chimeric Antigen Receptor T Cell Therapy followed by Unrelated Cord Blood Transplantation for the Treatment of Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia in Children and Young Adults: Superior Survival but Relatively High Post-Transplantation Relapse. (ucdavis.edu)

However, these neoplasms have a distinct nodular appearance without abundant lymphocytes and plasma cells typically seen in Hashimoto thyroiditis. (cap.org)
A bone core biopsy shows diffuse infiltration by small lymphocytes and plasma cells (A). Dutcher bodies (intra-nuclear pseudo-inclusions comprised of immunoglobulin) are readily identified (B). (hematology.org)

2005). The vascular endothelial growth factor (VEGF) is a 46 kD dimeric glycoprotein secreted by neoplastic cells, macrophages, plasma cells and lymphocytes, which triggers endothelial cell proliferation by interacting with specific receptors in a paracrine or autocrine fashion (Ferrara 2004). (vin.com)

Growth factors such as fibroblast growth factor (FGF), vascular endothelial cell growth factor (VEGF), and angiopoietin-1 (Ang1) are upregulated to stimulate angiogenesis, while downregulation of endogenous protein inhibitors (thrombospondin 1 and interferon) disrupts the balance of physiologic angiogenesis. (cancernetwork.com)

Mutations in the epithelial cadherin (E-cadherin) gene have been shown to be associated with the occurrence of diffuse gastric carcinomas in affected families. (tum.de)
CONCLUSION: Our immunohistochemical studies might suggest that the gastrinoma-associated excessive progastrin tissue concentrations led to diminished expression of E-cadherin within the gastric mucosa and promoted tumor development of a signet-ring cell carcinoma. (tum.de)
Epstein-Barr virus-associated gastric carcinoma (EBVaGC) is a distinct subtype that accounts for nearly 10% of gastric carcinomas. (spandidos-publications.com)
In 1990, Burke et al ( 3 ), first reported the association between EBV and gastric carcinoma with characteristic lymphoepithelioma-like histology based on polymerase chain reaction (PCR) techniques. (spandidos-publications.com)
In gastric carcinoma cells, EBV is not integrated into the host genome but maintained as a type of plasmid called an episome. (spandidos-publications.com)
The reason for this is that Helicobacter Pylori ( H. pylori ), discovered in 1983 by Marshall and Warren, and classified as a definite carcinogen by World Health Organization in 1994, has been regarded as the major factor in almost all gastric carcinomas worldwide ( 7 - 9 ). (spandidos-publications.com)
In addition to accumulating more case series of EBV-associated gastric carcinoma (EBVaGC), the development of comprehensive molecular analyses has provided evidence that EBVaGC is a distinct subset both in terms of its clinicopathological and molecular features. (spandidos-publications.com)

Anaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy for which no effective therapy exists. (unibe.ch)

Another statement showed the preadipocyte- and endothelial cell-derived stromal-derived element-1 (CXCL12), mediated early infiltration of CD4+ T lymphocytes in obesity, which preceded the increase of macrophages in adipose cells of mice on HFD (101). (exposed-skin-care.net)

Here we reported that SP patients exhibited decreased plasma levels of, IL-17A, IFN-γ, IL-12p70 and TNF-α when compared with PV patients, suggesting that analysis of the cytokine production profile may be an useful diagnostic biomarker to distinguish PV from SP patients. (nature.com)
Among its different constituents, Astragalus polysaccharides have been most widely studied particularly for their immunopotentiating properties, such as stimulation of murine B cell proliferation and cytokine production ( 6 ). (spandidos-publications.com)
Homozygotes for targeted null mutations exhibit impaired IL4 responses, including anti-IgM stimulated B cell proliferation, class switching to IgE, contact sensitivity, and Th2 cytokine production, and show increased resistance to certain infections. (jax.org)

CRC cells secreted extracellular miR-224-5p mainly in an exosome-dependent manner, and then miR-224-5p could be transferred to surrounding tumor cells to regulate cell proliferation in the form of autocrine or paracrine. (besjournal.com)
The percentage of VEGF-positive tumor cells was scored at 0 to 4 levels (0: less than de 5% of labeled cells to 4: more than 75% of labeled cells). (vin.com)
Calebin-A induced death of malignant peripheral nerve sheath tumor cells by activation of histone acetyltransferase. (cancerindex.org)
ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)

Clear cell acanthoma is characterized by a sharply demarcated psoriasiform epidermal hyperplasia composed of a proliferation of slightly enlarged keratinocytes, and basal cells with pale-staining glycogen-rich cytoplasm, mild spongiosis and scattered neutrophils, which may form small intraepidermal microabscesses. (wikipedia.org)
1991. Control of 1,2-dimethylhydrazine-induced crypt hyperplasia by naturalkiller cells and its relevance to carcinogenics. (cdc.gov)

Hürthle cell neoplasms of the thyroid show a distinct nodule or nodules that are comprised mostly of large oncocytes with distinct cell borders, deeply eosinophilic and granular cytoplasm, and a large nucleus with prominent nucleolus. (cap.org)

Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells. (louisville.edu)

Histone adsorption on the surface of carbon particles significantly stimulates their ingestion by rat peritoneal macrophages, hamster kidney fibroblasts, and mouse L-cells [ 861 ], and the adsorption of polycyclic aromatic hydrocarbons (PAHs) and their nonpolar metabolites on the surface of carbon particles ingested by rat alveolar macrophages has been studied [ 862 ]. (nanomedicine.com)

These brief peptide sequences in the antigen are often presented over the cell surface area of APCs by using MHCII substances, which are necessary for activation of Compact disc4+ T cells (102). (exposed-skin-care.net)
Indeed, the principal adipocytes isolated from obese mice could induce antigen-specific Compact disc4+ T cell activation (58). (exposed-skin-care.net)
Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an activation marker for B or T cells). (medscape.com)

On the surface of lymphoid cells, myeloid cells and other non-hematopoietic tissue cells, the expression of CD38 shows is lower, but on the surface of malignant plasma cells such as myeloma cells, CD38 shows high expression. (cusabio.com)

There are atrophic follicles with abundant Hürthle cells/oncocytes intermixed with scattered areas of fibrosis and giant cell reaction limited to the thyroid parenchyma. (cap.org)
Centrally, the cells enlarge and accumulate abundant intracellular glycogen, with a resultant pale glossy appearance. (scitechnol.com)
The cells are usually large and polygonal, containing abundant eosinophilic cytoplasm, a large nucleus with open chromatin, a prominent eosinophilic nucleolus, and an occasional intracellular lumina containing red blood cells 1,4-7 . (bvsalud.org)
Histologically, ALCL is characterized by sheets of large pleomorphic cells with abundant cytoplasm, horseshoe- or wreath-shaped nuclei, and multiple prominent nucleoli. (medscape.com)

It is characterized by plasma cell bone marrow infiltration and accumulation of monoclonal protein in the serum and urine [ 1 ]. (thejh.org)
The bone marrow demonstrated a diffuse proliferation of small lymphocytes admixed with plasmacytoid lymphocytes and clusters of plasma cells. (hematology.org)
The bone marrow often shows increased mast cells. (hematology.org)
A bone marrow biopsy is usually performed to estimate the percentage of bone marrow occupied by plasma cells. (the-medical-dictionary.com)
Solitary extramedullary plasmacytoma (SEP) is a neoplastic proliferation of a single clone of plasma cells that occur outside of the bone and bone marrow. (scielo.org.za)
A normocellular microscopical appearance, with no plasma cell dyscrasia, was displayed on the bone marrow aspirate. (scielo.org.za)
chronic myeloid leukemia (cml) is characterized by increased and unregulated proliferation of granulocytic lineage in the bone marrow and presence of these immature myeloid cells in the peripheral blood with presence of philadelphia (ph) chromosome. (liverpool.ac.uk)

Another important mechanism for the progression of colorectal cancer is the ability of the transformed cells to invade and traverse the basement membrane, which in turn facilitates the conversion of adenomas into carcinomas and then metastases ( 1 ). (spandidos-publications.com)

The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)

abstract = "Unlike other ErbB family members, HER2 levels are maintained on the cell surface when the receptor is activated, allowing prolonged signaling and contributing to its transforming ability. (korea.ac.kr)

Immunohistochemical stains on the core biopsy showed diffuse infiltration of CD20-positive B-cells, and increased kappa-restricted CD138-positive plasma cells. (hematology.org)
Immunohistochemical stains show diffuse proliferation of CD20-positive B-cells (A). Clusters of CD138-positive plasma cells are also present (B). These were kappa-restricted (C) with only occasional lambda-positive cells (D). (hematology.org)

Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
In the primary prevention component of the Helsinki Heart Study, in which 4081 male patients between the ages of 40 and 55 were studied in a randomized, double-blind, placebo-controlled fashion, gemfibrozil therapy was associated with significant reductions in total plasma triglycerides and a significant increase in high density lipoprotein cholesterol. (nih.gov)
Among Fredrickson types, during the 5-year double-blind portion of the primary prevention component of the Helsinki Heart Study, the greatest reduction in the incidence of serious coronary events occurred in Type IIb patients who had elevations of both LDL-cholesterol and total plasma triglycerides. (nih.gov)

This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. (cancerindex.org)
while this machinery was originally identified by its ability to allow cells to survive starvation via lysosomal degradation to recycle cellular components, it has recently become apparent that it also is used by cells to secrete cytoplasmic constituents. (liverpool.ac.uk)

Neoplasms containing cyst-like formations or producing mucin or serum. (lookformedical.com)
Some of the patients with this variant of Hashimoto thyroiditis may have IgG4 thyroiditis and show a predominant interfollicular pattern of fibrosis, along with increased IgG4-positive plasma cells and increased serum IgG. (cap.org)

efficient and reliable establishment of lymphoblastoid cell lines by epstein-barr virus transformation from a limited amount of peripheral blood. (liverpool.ac.uk)

Cervical carcinoma is a major gynecological cancer and causes cancer-related deaths in worldwide, the latent pathogenesis and progress of cervical cancer is still under research. (biomedcentral.com)
this suggests that ClC-3 may function as a patent tumour biomarker and a latent therapeutic target for cervical carcinoma patients. (biomedcentral.com)

Oedematous dermal papillae are typically seen with increased vascularity and a mixed inflammatory infiltrate including lymphocytes, plasma cells and neutrophils. (wikipedia.org)
Ability of neoplasms to infiltrate and actively destroy surrounding tissue. (lookformedical.com)

In addition, cytoplasmic vacuoles are not uncommon in large cell lymphomas involving body cavities. (cytojournal.com)
mature T/NK-cell lymphomas (C84. (who.int)

1.2 ] - #kynurenine -a tryptophan metabolite that blocks antitumour immunity-inhibits T cell proliferation in a manner that can be rescued by BH4. (metabiom.org)
Initial control of EBV in healthy persons involves NK cells that can kill virus-infected cells ( 3 , 4 ) and secrete IFN-γ, which inhibits B cell proliferation, and monocytes, which release chemokines in response to virus infection ( 5 ). (frontiersin.org)

Anatomy30

Organisms8

Diseases72

Chemicals and Drugs73

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Phenomena and Processes37

Disciplines and Occupations1

Information Science4

Health Care4

Differentiation8

Apoptosis7

Tumors16

Metastasis5

Multiple myeloma6

Renal8

Nasopharyngeal carcinoma3

Squamous1

Monoclonal proliferation1

Tissues9

Benign5

Invasiveness2

Immunohistochemistry1

Malignant neoplasm2

Myeloproliferative neoplasm1

Clonal5

Spindle cell3

LIVER4

Lymphoma11

Urothelial carcinoma2

Hepatocellular carcinoma1

Abnormal3

Antigens3

Migration6

Adenoma2

Cancers6

Papillary3

Ovarian carcinoma1

Malignancies1

Survival3

Lymphocytes and plasma cells2

Receptors1

Vascular endothelial1

Gastric7

Malignancy1

Endothelial cell1

Cytokine production3

Tumor cells4

Hyperplasia2

Nodules1

Inhibition1

Macrophages1

Antigen3

Lymphoid1

Abundant4

Bone7

Metastases1

Histologically1

Abstract1

Diffuse2

Primary3

Cellular2

Serum2

Transformation1

Latent2

Infiltrate2

Lymphomas2

Inhibits2