• study
  • An adduct site-specific study is most useful when it is compared to a mutagenesis study with its corresponding mutagen/carcinogen. (oup.com)
  • Thus, it is important to match the conditions of the adduct study versus the mutagen/ carcinogen study as closely as possible. (oup.com)
  • Given what is known about chemical carcinogens in MCS, this study shows that there is a higher incidence of lung cancer from exposure to MCS than can be predicted with current risk assessment methods using available toxicity and emission data. (pubmedcentralcanada.ca)
  • conditions
  • Mutations induced by a particular mutagen/carcinogen can be influenced by DNA sequence context, mutagen/carcinogen dose (and other changes in conditions), level of SOS induction, cell type and other factors. (oup.com)
  • 92:106-111) for MCS emissions of three carcinogens measured under human smoking conditions to compute probability distributions of incremental lifetime cancer risk (ILCR) values using Monte Carlo simulations. (pubmedcentralcanada.ca)