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  • contaminants
  • This monograph reviews the experimental evidence concerning the carcinogenicity of the aflatoxins, evaluates the potencies of these contaminants, links these potencies to intake estimates, and discusses the impact of hypothetical standards on sample populations and their overall risks. (inchem.org)
  • The United States Department of Agriculture describes aflatoxins as "unavoidable contaminants of food and feed, even where good manufacturing practices have been followed. (cancerdefeated.com)
  • they are included in the "contaminants", which are not intentionally added to food but which are defined as chemical substances that contaminate food at various stages of production, including primary production, for environmental or other reasons, or forming at that stage in foodstuffs. (safefoodsafefuture.org)
  • IARC
  • In 1971 aflatoxins were reviewed in Volume 1 of the International Agency for Research on Cancer (IARC) Monographs on the Evaluation of Carcinogenic Risk and again in Volume 56 of the IARC monographs in 1993. (inchem.org)
  • antibody
  • While AF M1 antibody and HRP secondary antibody (HRP material) combined, via the TMB substrate show color, sample absorbance values of aflatoxin M1 has a negative correlation with its content, compared with the standard curve and then multiplied by the corresponding the dilution factor, can draw aflatoxin M1 content in samples. (krishgen.com)
  • corn
  • Described by scientists as among the most potent mutation-causing and carcinogenic substances known, these chemicals already destroy a quarter of the entire world's food crop annually before it even gets to anyone's plate, and in a bad year the economic losses in just the corn crop alone can top $1.7 billion in the US. (cancerdefeated.com)
  • liver
  • After entering the body, aflatoxins may be metabolized by the liver to a reactive epoxide intermediate or hydroxylated to become the less harmful aflatoxin M1. (wikipedia.org)
  • Animal and human studies show aflatoxins trigger genetic mutations, promote cancer, cause fetal malformations and suppress the immune system, with the liver being the main target organ. (cancerdefeated.com)
  • grains
  • High concentrations of aflatoxins are most often found in plants with very nutritive seeds such as maize, nuts, and cereal grains in Africa and rice in China and Southeast Asia . (encyclopedia.com)
  • stable
  • As aflatoxin M1 is relatively stable towards the pasteurizing process, not only a comprehensive routine check of the raw materials to be processed is required, but also of the final products. (equl.com)
  • found
  • When contaminated food is processed, aflatoxins enter the general food supply where they have been found in both pet and human foods, as well as in feedstocks for agricultural animals. (wikipedia.org)
  • The Food and Drug Administration (FDA) said they found Aflatoxin B1 beyond the acceptable limit in the tested samples of peanut products made here and abroad. (thefreedictionary.com)
  • M1 is frequently found in milk and other dairy products. (cancerdefeated.com)
  • Dietary
  • The Committee urged that the intake of dietary aflatoxin be reduced to the lowest practicable levels so as to reduce, as far as possible, the potential risk. (inchem.org)
  • Africa
  • As a result, people who live in the regions of the world most prone to these conditions, such as sub-Saharan Africa and southeast Asia , are at highest risk for aflatoxin poisoning. (encyclopedia.com)
  • group
  • This group is addressed separately from the undesirable chemical substances in the following groups, which are a highly controllable field of system for assessing risks. (safefoodsafefuture.org)
  • samples
  • For example, contaminated poultry feed is suspected in the findings of high percentages of samples of aflatoxin-contaminated chicken meat and eggs in Pakistan. (wikipedia.org)
  • Thin-layer chromatography has been a common method of aflatoxin detection, but sample preparation and samples analysis of this method is time-consuming and exhausting. (krishgen.com)
  • IARC
  • In 1971 aflatoxins were reviewed in Volume 1 of the International Agency for Research on Cancer (IARC) Monographs on the Evaluation of Carcinogenic Risk and again in Volume 56 of the IARC monographs in 1993. (inchem.org)
  • contaminants
  • This monograph reviews the experimental evidence concerning the carcinogenicity of the aflatoxins, evaluates the potencies of these contaminants, links these potencies to intake estimates, and discusses the impact of hypothetical standards on sample populations and their overall risks. (inchem.org)
  • The United States Department of Agriculture describes aflatoxins as "unavoidable contaminants of food and feed, even where good manufacturing practices have been followed. (cancerdefeated.com)
  • potent
  • Described by scientists as among the most potent mutation-causing and carcinogenic substances known, these chemicals already destroy a quarter of the entire world's food crop annually before it even gets to anyone's plate, and in a bad year the economic losses in just the corn crop alone can top $1.7 billion in the US. (cancerdefeated.com)
  • molds
  • The presence of those molds does not always indicate that harmful levels of aflatoxin are present, but does indicate a significant risk. (wikipedia.org)
  • AFB1
  • In this study, we investigated the mechanism underlying age-related susceptibility in broilers to aflatoxin B1 (AFB1). (atgcchecker.com)
  • genetic
  • Animal and human studies show aflatoxins trigger genetic mutations, promote cancer, cause fetal malformations and suppress the immune system, with the liver being the main target organ. (cancerdefeated.com)
  • grains
  • High concentrations of aflatoxins are most often found in plants with very nutritive seeds such as maize, nuts, and cereal grains in Africa and rice in China and Southeast Asia . (encyclopedia.com)
  • detection
  • Thin-layer chromatography has been a common method of aflatoxin detection, but sample preparation and samples analysis of this method is time-consuming and exhausting. (krishgen.com)
  • human
  • Aflatoxins were evaluated at the thirty-first meeting of the Committee (Annex 1, reference 77), at which time the Committee considered aflatoxin to be a potential human carcinogen. (inchem.org)
  • Risk
  • The Committee urged that the intake of dietary aflatoxin be reduced to the lowest practicable levels so as to reduce, as far as possible, the potential risk. (inchem.org)
  • As a result, people who live in the regions of the world most prone to these conditions, such as sub-Saharan Africa and southeast Asia , are at highest risk for aflatoxin poisoning. (encyclopedia.com)
  • High
  • For example, contaminated poultry feed is suspected in the findings of high percentages of samples of aflatoxin-contaminated chicken meat and eggs in Pakistan. (wikipedia.org)