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Repetitive Sequences, Nucleic AcidAmino AcidsSequence Homology, Amino AcidAmino Acid SequenceBase SequenceCloning, MolecularMolecular Sequence DataDNASequence Homology, Nucleic AcidAmino Acid SubstitutionSequence AlignmentNucleic Acid HybridizationNucleic Acid RenaturationSequence Analysis, DNAInterspersed Repetitive SequencesRestriction MappingRepetitive Sequences, Amino AcidMutationBinding SitesEscherichia coliAmino Acids, EssentialBlotting, SouthernChromosome MappingDNA Transposable ElementsDNA, ComplementarySpecies SpecificityAmino Acid Transport SystemsPolymerase Chain ReactionGenesKineticsDNA Restriction EnzymesAlu ElementsPlasmidsDNA, PlantGenome, PlantPhylogenyLong Interspersed Nucleotide ElementsAmino Acid MotifsMutagenesis, Site-DirectedMolecular WeightRecombinant ProteinsGene LibraryDNA, SatellitePeptide FragmentsCell LineProtein BindingChromosomes, Artificial, BacterialProtein ConformationDNA PrimersConserved SequenceStructure-Activity RelationshipProtein Structure, TertiaryEvolution, MolecularPeptidesRNA, MessengerCentromereModels, MolecularTranscription, GeneticDNA, BacterialBacterial ProteinsDendrobiumTandem Repeat SequencesShort Interspersed Nucleotide ElementsSequence DeletionSubstrate SpecificityGenomic LibraryAmino Acids, AromaticElectrophoresis, Polyacrylamide GelGenes, BacterialProteinsPhysical Chromosome MappingLeucineAmino Acids, Branched-ChainGenetic VariationRecombinant Fusion ProteinsAmino Acids, SulfurDNA ProbesDNA, FungalPrimed In Situ LabelingCattleDNA, RecombinantMultigene FamilyIn Situ Hybridization, FluorescenceHeterochromatinOpen Reading FramesExonsTransfectionSequence AnalysisBase CompositionChromosome WalkingCodonSaccharomyces cerevisiaeCosmidsChromosomes, PlantChromosomesDeoxyribonuclease BamHIProtein Structure, SecondaryAlanineProtein BiosynthesisRNA
ProteinsNucleic AcidsNucleotide sequencesPolypeptideSpecific aminoTerminusAmidoProteinMutationSuperfamilyMECP2TranscriptionalPrecursorEssentialCodonSynthesisOccurInhibitOccursDOPAMINERodentGenesEnzymeGroupFormResultsIncludeMethodsOrderGenerallyWide rangeRetainsHumanRegionShortPropertiesProductsPresentChainRepairNaturalBetaCollectionNORMAL
Proteins14
  • A) Amino acid sequences of designed silk modules were derived from dragline silk proteins ADF-3 and ADF-4 and back translated into nucleotide sequences using the bacterial codon usage. (biomedcentral.com)
  • These repeat units were multimerized to generate synthetic genes coding for the repetitive proteins (rep-proteins) (AQ) n and (QAQ) n . (biomedcentral.com)
  • The specificity of the proteins is determined by the sequences outside the repeats themselves. (embl.de)
  • We chose proteins that include amino and carboxyl extensions as well as proteins that are made up entirely of WD-repeats. (embl.de)
  • All proteins end with a carboxyl terminus that has unique biophysical properties and is often disordered. (stanford.edu)
  • Minimotifs are modular contiguous peptide sequences in proteins that are important for posttranslational modifications, binding to other molecules, and trafficking to specific subcellular compartments. (stanford.edu)
  • Some molecular functions of proteins in cellular pathways can be predicted from minimotif consensus sequences identified through experimentation. (stanford.edu)
  • All translated proteins end with a carboxylic acid commonly called the C-terminus. (stanford.edu)
  • By searching for new anchored sequences on the last 10 amino acids of proteins in the human proteome with lengths between 3-10 residues and up to 5 degenerate positions in the consensus sequences, we have identified new consensus sequences that predict instances in the majority of human genes. (stanford.edu)
  • An essential branched-chain aliphatic amino acid found in many proteins . (lookformedical.com)
  • Twenty alpha-amino acids are the subunits which are polymerized to form proteins . (lookformedical.com)
  • The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS . (lookformedical.com)
  • This study investigated the multiproduct (fucoidans, ß-glucans, proteins, carotenoids, fatty acids, amino acids and polyphenols) valorization of the invasive macroalgae Ascophyllum nodosum within a green biorefinery concept using ultrasound (US), microwave (MW) treatment followed by supercritical CO2 (SC-CO2) with co-solvent and enzymatic extraction. (bvsalud.org)
  • However, US/MW pretreatment and enzymatic extraction did not improve the yields of proteins and free amino acids. (bvsalud.org)
Nucleic Acids3
  • Nucleic acids convey genetic information. (spilianakislab.gr)
  • Polypyrimidine tract binding protein and associated splicing factor (PSF) has diverse functions inside the cell such as transcriptional regulation, DNA repair, acts as nucleic acids binding protein and regulate replication and infectivity of different viruses. (biomedcentral.com)
  • The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. (lookformedical.com)
Nucleotide sequences1
  • Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. (lookformedical.com)
Polypeptide5
  • 1.Genetic code is the relationship between the sequence of nucleotides on mRNA and the sequence of amino acids in the polypeptide. (infinitylearn.com)
  • 6. Translation is the process of polymerisation of amino acids to form a polypeptide. (infinitylearn.com)
  • The order of amino acids as they occur in a polypeptide chain. (lookformedical.com)
  • The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. (lookformedical.com)
  • the invention also provides non-human animals and cells comprising a transgene encoding an APP comprising the Swedish mutation and further comprising functionally disrupted endogenous APP gene loci, transgenes and targeting constructs used to produce such transgenic cells and animals, transgenes encoding human Swedish mutation APP polypeptide sequences, and methods for using the transgenic animals in pharmaceutical screening and as commercial research animals for modeling neurodegenerative diseases (e.g. (justia.com)
Specific amino1
  • 5.Francis Crick postulated the presence of an adapter molecule that would on one hand read the code and on other hand would bind to specific amino acids. (infinitylearn.com)
Terminus4
  • There are also unusual, repetitive sequences found at the carboxyl terminus. (wikipedia.org)
  • Many short functional sequences (minimotifs) are located on or immediately proximal to the C-terminus. (stanford.edu)
  • Mutations in the amino-terminus were significantly correlated with a more severe clinical presentation compared with mutations closer to the carboxyl-terminus of MeCP2. (neurology.org)
  • secretase" at the amino-terminus of the .beta. (justia.com)
Amido1
  • amid group and carbonyl group are parallel along axis of the helix with the carbonyl groups pointing towards the carboxyl end and amido groups toward the amino end. (flashcardmachine.com)
Protein6
  • The repetitive part of ADF-4 is generally composed of a single consensus module termed C, which was multimerized to obtain the rep-protein C n . (biomedcentral.com)
  • ii)Frameshift mutation occurs where addition/insertion or deletion of one or two bases changes the reading frame from the site of mutation, resulting in a protein with a different set of amino acids. (infinitylearn.com)
  • Insertion or deletion of three of its multiples of bases do not alter the reading frame but one/more amino acids are coded in the protein translated. (infinitylearn.com)
  • An unnatural amino acid that is used experimentally to study protein structure and function. (lookformedical.com)
  • secretase" which cleaves between amino acids 16 and 17 of the protein. (justia.com)
  • amyloid precursor protein (.beta.APP), which is expressed in differently spliced forms of 695, 751, and 770 amino acids. (justia.com)
Mutation2
  • i)Point mutation occurs due to change in single base pair.Its example is a change of single base pair in the gene for beta-globin chain of haemoglobin that results in the change of amino acid residue glutamate to valine. (infinitylearn.com)
  • iii)Silent mutation occurs when a base change in a codon does not alter the amino acid coded. (infinitylearn.com)
Superfamily3
  • The peptide transporter carbon starvation (CstA) family (transporter classification [TC] 2.A.114) belongs to the second largest superfamily of secondary transporters, the amino acid/polyamine/organocation (APC) superfamily. (cipsm.de)
  • An octameric enzyme belonging to the superfamily of amino acid dehydrogenases. (lookformedical.com)
  • A large superfamily of transcription factors that contain a region rich in BASIC AMINO ACID residues followed by a LEUCINE ZIPPER domain. (lookformedical.com)
MECP21
  • One hundred sixteen patients with classical and atypical RTT were studied for mutations of the MeCP2 gene by using DHPLC and direct sequencing. (neurology.org)
Transcriptional1
  • and a transcriptional repression domain (TRD) composed of 104 amino acids The MBD domain forms a wedge and attaches to the methylated CpG sites on the DNA strands. (wikipedia.org)
Precursor1
  • It is an amine synthesized by removing a carboxyl group from a molecule of its precursor chemical L-DOPA , which is synthesized in the brain and kidneys . (alchetron.com)
Essential3
  • 2. Collagen production: Amino acids are essential for collagen synthesis, which is vital for maintaining skin elasticity and firmness. (eloraclinic.com)
  • A branched-chain essential amino acid that has stimulant activity. (lookformedical.com)
  • A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. (lookformedical.com)
Codon3
Synthesis1
  • iv)Severo Ochoa enzyme (polynucleotide phosphoryiase) was also helpful in polymerising RNA with defined sequences in a template independent manner (enzyme synthesis of RNA). (infinitylearn.com)
Occur1
  • a)Activation of amino acids occur in presence of ATP and link to their cognate fRNA, i.e. charging of fRNA or aminoacylation of fRNA. (infinitylearn.com)
Inhibit2
  • The non-WD-repeat amino terminal alpha helix of G beta does not inhibit folding because G beta does not fold even when this region is removed. (embl.de)
  • 5. Brightening and even skin tone: Some amino acids have been found to inhibit melanin production, which can help reduce the appearance of dark spots, hyperpigmentation, and uneven skin tone. (eloraclinic.com)
Occurs1
  • small piece of non-repetitive structure that occurs by itself, but most often it occurs as an irregularity in antiparallel Beta structures. (flashcardmachine.com)
DOPAMINE1
  • Because of the increased stability and water-solubility of the protonated form, dopamine is supplied for chemical or pharmaceutical use as dopamine hydrochloride -that is, the hydrochloride salt that is created when dopamine is combined with hydrochloric acid . (alchetron.com)
Rodent1
  • To help evaluate the function of the remaining C-termini in the human proteome, we inferred minimotifs identified by experimentation in rodent cells, predicted minimotifs based upon consensus sequence matches, and predicted novel highly repetitive sequences in C-termini. (stanford.edu)
Genes1
  • Additionally, carboxyl-terminal non-repetitive (NR)-regions from the natural genes were amplified by PCR and optionally linked with the synthetic genes [50]. (biomedcentral.com)
Enzyme3
  • A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. (lookformedical.com)
  • A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the reversible transamination of branched-chain AMINO ACIDS to 2-oxoglutarate. (lookformedical.com)
  • An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE , forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. (lookformedical.com)
Group1
  • Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. (lookformedical.com)
Form1
  • Oct. 26, 1993, Abstract No. 15.4, Anaheim, Calif.) which contains more of the .beta.AP sequence carboxy terminal to that form described by Esch et al. (justia.com)
Results2
  • RESULTS: Mannose, Betaine, Xanthine, Triglyceride (38:1), Sphingomyelin (d63:7), and Phosphatidic acid (37:2) are some of the top key biomarkers of diabetes. (bvsalud.org)
  • The Elora Clinic Amino Acid Serum is enriched with potent ingredients that work together to deliver exceptional results. (eloraclinic.com)
Include1
  • Examples of methods utilizing such non-radioactive detection methods include DNA sequencing, oligonucleotide probe methods, detection of polymerase-chain-reaction products, immunoassays, and the like. (justia.com)
Methods3
  • In an additional aspect, the invention includes methods utilizing such dye compounds and reagents including dideoxy polynucleotide sequencing and fragment analysis methods. (justia.com)
  • In many applications the independent detection of multiple spatially overlapping analytes in a mixture is required, e.g., single-tube multiplex DNA probe assays, immuno assays, multicolor DNA sequencing methods, and the like. (justia.com)
  • In the case of automated DNA sequencing, multicolor labeling allows for the analysis of all four bases in a single lane thereby increasing throughput over single-color methods and eliminating uncertainties associated with inter-lane electrophoretic mobility variations. (justia.com)
Order1
Generally1
  • As a base, it is generally protonated in acidic environments (in an acid-base reaction). (alchetron.com)
Wide range1
Retains1
  • Hyaluronic acid, a powerful humectant , attracts and retains moisture, helping to plump and hydrate the skin. (eloraclinic.com)
Human2
  • In contrast, thrombin receptor-activating peptides derived from the human PAR 1 receptor sequence (e.g. (aspetjournals.org)
  • Amino acids that are not synthesized by the human body in amounts sufficient to carry out physiological functions. (lookformedical.com)
Region1
  • This region is closely related to the fork head family, at the amino acid level. (wikipedia.org)
Short1
  • Inside experiment Only two (the particular short-term try things out), goat's ended up infused with phenylalanine pertaining to 10h continuously with the same infusion price because try things out A single after supply starvation with regard to 24h repetitive every single 10day. (hif-signals.com)
Properties1
  • 4. Protection against environmental stressors: Amino acids have antioxidant properties that protect the skin from environmental damage caused by free radicals, UV radiation, pollution, and other harmful factors. (eloraclinic.com)
Products1
  • Incorporating skincare products enriched with amino acids can provide your skin with these incredible benefits and contribute to a healthier, more radiant appearance. (eloraclinic.com)
Present1
Chain1
Repair1
  • 3. Repair and regeneration: Amino acids support the skin's natural repair processes, aiding in the healing of damaged or wounded skin. (eloraclinic.com)
Natural1
  • 1. Moisturization: Amino acids help to enhance the skin's natural moisture retention abilities, keeping it hydrated and plump. (eloraclinic.com)
Beta1
Collection2
  • The Amino Acid Serum is from Elora Clinic Complete Care Collection. (eloraclinic.com)
  • This product (Amino Acid Serum) is perfectly suitable for oily skin however we also recommend our oil-free serums from simply advanced collection for better result. (eloraclinic.com)
NORMAL1