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  • substrate
  • Carbohydrate-binding module family 6 (CBM6) is unusual in that is contains two substrate-binding sites, cleft A and cleft B. Cellvibrio mixtus endoglucanase 5A contains two CBM6 domains, the CBM6 domain at the C-terminus displays distinct ligand binding specificities in each of the sustrate-binding clefts. (wikipedia.org)
  • It includes a thermostable alpha-amylase with a broad substrate specificity from the archaebacterium Pyrococcus furiosus. (wikipedia.org)
  • In the mammary gland, alpha-lactalbumin changes the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose. (wikipedia.org)
  • gene
  • In all eukaryotes, the precise regulation of transcription of any given gene is ultimately determined by the combinatorial binding of sequence-specific transcription factors (TFs) to their target sequences within promoters, enhancers, and other genomic regulatory regions. (plantcell.org)
  • In equids the beta subunit polypeptides of luteinizing hormone and chorionic gonadotropin are identical in sequence, differing only in their carbohydrate side-chains, and are the product of a single gene. (wikipedia.org)
  • As the pro-region of trypsinogen contains this sequence, enteropeptidase catalyses its activation in vivo: trypsinogen → trypsin + pro-region (Val-Asp-Asp-Asp-Asp-Lys) In humans, enteropeptidase is encoded by the PRSS7 gene (also known as ENTK) on chromosome 21q21. (wikipedia.org)
  • Carbohydrate sulfotransferase 4 is an enzyme that in humans is encoded by the CHST4 gene. (wikipedia.org)
  • Carbohydrate sulfotransferase 2 is an enzyme that in humans is encoded by the CHST2 gene. (wikipedia.org)
  • ligand
  • Furthermore, the extraordinary variability of FTL sequences (isoforms) that are expressed in a single individual has revealed genetic mechanisms of diversification in ligand recognition that are unique to FTLs. (frontiersin.org)
  • thermostable
  • The nanoCLAMP scaffold is based on an IgG-like, thermostable carbohydrate binding module family 32 (CBM32) from a Clostridium perfringens hyaluronidase (Mu toxin). (wikipedia.org)
  • disulfide
  • Carbohydrate-binding module family 2 (CBM2) contains two conserved cysteines - one at each extremity of the domain - which have been shown to be involved in a disulfide bond. (wikipedia.org)
  • interactions
  • Carbohydrates are crucial for most organisms as carbon sources or as signaling molecules, but also for cell wall synthesis, host pathogen interactions, energy storage etc. (univ-mrs.fr)
  • Although each individual docking interaction is weak, many interactions occur simultaneously, conferring a cumulative effect on binding specificity. (wikipedia.org)
  • structure
  • During the last 20 years we have developed a classification in sequence-based families that correlate with the structure and catalytic mechanism of CAZymes. (univ-mrs.fr)
  • The past decade has provided a wealth of structural and thermodynamic data that provide insight on how oligosaccharide specificity, quaternary structure, and metal binding cooperate to generate a variety of biological effects. (plantphysiol.org)
  • HUMAN
  • The targeted DNA sequence is the CCAAT box, originally discovered in human promoters, and later found in all eukaryotes. (plantcell.org)
  • 1. A composition comprising human serine protease being substantially free of killer cell granule components, said human serine protease having an amino acid sequence as setforth in FIGS. 1a-1c. (patentgenius.com)
  • family
  • Glycoside hydrolase family 73 CAZY GH_73 includes peptidoglycan hydrolases with endo-β-N-acetylglucosaminidase specificity. (wikipedia.org)
  • Carbohydrate-binding module family 1 (CBM1) consists of 36 amino acids. (wikipedia.org)
  • Carbohydrate-binding module family 4 (CBM4) includes the two cellulose-binding domains, CBD(N1) and CBD(N2), arranged in tandem at the N terminus of the 1,4-beta-glucanase, CenC, from Cellulomonas fimi. (wikipedia.org)
  • novel
  • The inferred metabolic regulons provide new insights on diverse carbohydrate utilization networks in bifidobacteria that can be employed in metabolic modeling, phenotype prediction and the rational development of novel prebiotics. (frontiersin.org)
  • include
  • Notably, conserved domains include the HFDs, required for heterodimerization and non-sequence-specific DNA binding, and a stretch of 56 amino acids of NF-YA, required for HFD association and specific CCAAT binding. (plantcell.org)
  • The name "peanut agglutinin" originates from its ability to stick together (agglutinate) cells, such as neuramidase-treated erythrocytes, which have glycoproteins or glycolipids on their surface which include the Gal-β(1-3)-GalNAc carbohydrate sequence. (wikipedia.org)
  • sugar
  • For example in PNA-affinity chromatography the binding specificity of peanut agglutinin is used to isolate glycosylated molecules which have the sugar sequence Gal-β(1-3)-GalNAc. (wikipedia.org)