• subunit
  • In re-organizing into the mature capsid lattice, each subunit of the precursor lattice must change its conformation, or its relationship with its neighbours, or both. (hindawi.com)
  • residues
  • Synthetic peptide corresponding to C terminal residues of Drosophila C virus DCV capsid polyprotein. (abcam.com)
  • The C-terminus also contains a basic nuclear localization sequence, while the N-terminus - which is oriented toward the center of the assembled capsid - contains basic residues that facilitate non-sequence-specific interactions with DNA. (wikipedia.org)
  • translocation
  • After endocytosis into the host cell, peptide gamma is probably exposed in endosomes, where it permeabilizes the endosomal membrane, facilitating translocation of viral capsid or RNA into the cytoplasm (By similarity). (uniprot.org)
  • copies
  • HIV-1 is composed of two copies of noncovalently linked, unspliced, positive-sense single-stranded RNA enclosed by a conical capsid composed of the viral protein p24, typical of lentiviruses. (wikipedia.org)
  • complexity
  • Here, we examine that question with respect to viral capsid assembly by studying the 'pathway complexity' of model capsid assembly systems, which we informally define as the number of reaction pathways and intermediates one must consider to accurately describe a given system. (hindawi.com)
  • amino
  • The weak forces at work include attraction or repulsion between electrostatic charges, water solubility, and constituent amino acid structures in various parts of the capsid. (asknature.org)
  • Further investigation during 2006 showed that assembly of capsid with portal depends on interaction of UL-6 with "scaffolding" protein UL-26.5, amino acids 143 through 151. (wikipedia.org)
  • assembly
  • The models provide complementary information in support of a common conclusion that the ability of simple pathway models to adequately explain capsid assembly kinetics varies considerably across the space of biologically meaningful assembly parameters. (hindawi.com)
  • Assembly of portal units is an initial step in constructing capsids of viral progeny. (wikipedia.org)
  • UL-6 associates with a UL-15/UL-28 protein complex during capsid assembly. (wikipedia.org)
  • The UL-15/UL-28 is believed to bind with viral DNA and serve the same purpose as terminase by packing viral DNA into the capsid during capsid assembly. (wikipedia.org)
  • Target
  • The capsid has become an attractive target for the development of new antiretroviral drugs. (nsf.gov)