• outbreaks
  • But a less crotchety Old Man Winter may actually have little to do with the recent outbreaks: While the panleukopenia virus is most comfortable at room temperature, it can survive a freeze and is resistant to heat up to about 133 degrees Fahrenheit. (petfinder.com)
  • A 2010 study published in the Journal of the American Veterinary Medical Association 1 found that 64.5% of dogs entering a Florida shelter that was struggling with outbreaks did not have protective antibody titers for CDV, CPV, or both. (maddiesfund.org)
  • Outbreaks of canine parvovirus associated with CPV-2c in the United States were confirmed in 2006 and 2007 in Arizona, California, Georgia, Oklahoma, and Texas. (chicagovma.org)
  • Kitties living in groups, for example, barn cats, feral cats and those living in stressful shelter and rescue situations are at highest risk of outbreaks of the disease. (mercola.com)
  • But utilizing what we now know about vaccines for the common preventable canine and feline diseases in shelter populations is possibly the single most powerful weapon we possess for stopping significant disease outbreaks in their tracks. (maddiesfund.org)
  • The outbreaks continued, with approximately 35% of the dogs dying. (maddiesfund.org)
  • veterinarian
  • The Chicago Veterinary Medical Association urges any new dog or cat owner to visit the veterinarian as soon as possible and start a comprehensive health care plan. (chicagovma.org)
  • Because some problems can be life threatening, vaccination of cats should be done only by a veterinarian or under the supervision of a veterinarian. (maxshouse.com)
  • Your veterinarian will take a complete history, including your cat's general health and whether he may have recently come in contact with other cats or spends time outside. (mercola.com)
  • Because these factors may change over time, many professional organizations recommend routine annual examinations, where a vaccination plan for each individual feline can be decided during a discussion between the veterinarian and cat owner. (wikipedia.org)
  • encode
  • Inside the capsid is a linear single-stranded DNA genome in the size range 4-6 kb so the small genome of parvovirus can encode only a few proteins. (wikipedia.org)
  • All parvoviruses encode two major gene complexes: the non-structural (or rep) gene that encodes the replication initiator protein (called NS1 or Rep), and the VP (or cap) gene, which encodes a nested set of ~2-6 size variants derived from the C-terminus of the single VP protein sequence. (wikipedia.org)
  • hepatitis
  • Cossart and her group were focused on hepatitis B and were processing blood samples when they discovered a number of "false positives" later identified as parvovirus B19. (wikipedia.org)
  • fatal
  • When asked to explain their decisions to the media and community members, spokespeople for many of these shelters use words like "forced," "had no choice," "fatal," and "deadly," creating the impression that the disease is not treatable and all affected dogs, perhaps even all exposed ones, will inevitably succumb. (maddiesfund.org)
  • However, a full blown case of parvovirus untreated can easily be fatal. (zoologix.com)
  • This genus includes canine parvovirus, which causes gastrointestinal tract damage in puppies that is about 80% fatal. (wikipedia.org)
  • kittens
  • I have been fostering a cat and kittens who tested positive for panleukopenia (distemper). (pets.ca)
  • In a big city with a sizable cat population, in an animal shelter with caring staff and progressive programs, in a bright and cheery cat adoption room, in a freshly disinfected cage full of kittens, an enemy in disguise lies waiting. (petfinder.com)
  • Severe disease caused by FPV is most commonly seen in kittens between 2 and 6 months of age, pregnant females and immunocompromised cats. (mercola.com)
  • necrosis
  • Parvovirus, however, is more serious and the presence of bloody diarrhea, a low white blood cell count, and necrosis of the intestinal lining also point more towards parvovirus, especially in an unvaccinated dog. (wikipedia.org)
  • shelter
  • Some blame the apparent increase in shelter panleukopenia cases on pet owners who may be getting nothing more than the requisite rabies vaccinations for their pets. (petfinder.com)
  • Are we potentially cheating shelter dogs out of "competent treatment" because of fear? (maddiesfund.org)
  • Cats can become infected through direct exposure to infected poop, saliva or viral particles left behind on food and water dishes, towels, bedding or surfaces around the home or shelter. (mercola.com)
  • symptoms
  • Its particular history, as well as its symptoms and outcomes, may as well have been tailor-made to inspire terror in the hearts of dog lovers, and make it hard for us to believe in its treatability. (maddiesfund.org)
  • In healthy adult cats, FPV is usually mild and can even go unnoticed or undetected because kitties don't show any symptoms. (mercola.com)
  • Usually symptoms of cerebellar hypoplasia can be seen immediately at birth in cats, but sometimes can take two months or so to become apparent in dogs. (wikipedia.org)
  • dehydration
  • Diarrhea and vomiting result in dehydration that upsets the electrolyte balance and this may affect the dog critically. (wikipedia.org)
  • Most panleukopenia deaths are due to secondary infections or dehydration resulting from diarrhea. (wikipedia.org)
  • Dehydration from prolonged or severe Click here to learn one way your vet may manage vomiting in dogs '}">vomiting is of immediate concern, and it may be necessary to admit your pet to the hospital for fluid replacement while a diagnosis is being pursued. (vetstreet.com)
  • kidney
  • Morphological studies of CPV-infected Norden laboratory feline kidney (NLFK) cells and canine fibroma cells (A72) displayed characteristic apoptotic events. (pubmedcentralcanada.ca)
  • For instance, a young energetic dog that is vomiting is more likely to have eaten something it shouldn't have, while a senior cat with weight loss, increased drinking, and vomiting is more likely to have a medical problem such as kidney disease or thyroid disease. (vetsecure.com)
  • gastrointestinal
  • The gastrointestinal tract and lymphatic system can be affected at any age, leading to vomiting, diarrhea and immunosuppression but cerebellar hypoplasia is only seen in cats that were infected in the womb or at less than two weeks of age, and disease of the myocardium is seen in puppies infected between the ages of three and eight weeks. (wikipedia.org)
  • respiratory
  • A couple of weeks ago, when the mother cat also came down with an upper respiratory infection, I started feeling ill too (this is the 2nd time I got sick at the same time as my cat). (pets.ca)
  • tend
  • This distinction is important because the medical conditions that tend to cause regurgitation are different from those associated with Click here to learn one way your vet may manage vomiting in dogs '}">vomiting . (vetstreet.com)
  • disease
  • The disease spread rapidly across the world, and thousands of dogs died from the infection. (wikipedia.org)
  • Dogs that develop the disease show signs of the illness within 3 to 7 days. (wikipedia.org)
  • This does not mean that all the dogs without protective titer levels were susceptible to disease. (maddiesfund.org)
  • Additionally, some dogs who had been exposed to or recovered from the disease itself had developed natural immunity. (maddiesfund.org)
  • If you've got a dog and a cat, though, it's difficult to know if one can catch a disease from the other. (thenest.com)
  • Therefore, a small percentage of cats vaccinated against a particular disease will not be immunized against that disease. (maxshouse.com)
  • The disease does not occur in dogs. (mercola.com)
  • The incidence of the disease is highest in young dogs and tends to start some time after the pup has lost its maternal antibody. (zoologix.com)
  • If the changes had been put into place earlier, many of the dogs that developed disease, including those that died, would have likely been saved. (maddiesfund.org)
  • The disease does not get better or worse with age, but the cat or dog can usually learn to somewhat compensate for it and should have a normal lifespan. (wikipedia.org)
  • prone
  • The epidemiological analysis revealed that the breed wise prevalence was found to be more in Deshi breeds as compared to others, age groups below 6 months were found to be more prone to parvovirus infection and males were mostly infected. (veterinaryworld.org)
  • Ask a Vet: What Makes Some Cats Uncoordinated and Prone to Staggering? (wikipedia.org)
  • feces
  • Panleukopenia is primarily spread through contact with an infected animal's bodily fluids, feces, or other fomites, as well as by fleas. (wikipedia.org)
  • Usually, feces from diarrheic dogs are screened using ELISA or hemagglutination (HA) assays, but these techniques have very low sensitivity. (zoologix.com)
  • protein
  • 1. A nucleic acid molecule encoding a parvovirus structural protein or fragment thereof, wherein at least about 50-100% of the nucleic acid molecule's codons are optimized for expression in a nonpermissive mammalian cell. (patentsencyclopedia.com)
  • 4. The nucleic acid molecule of claim 1, wherein the parvovirus structural protein or fragment thereof is a parvovirus B19 (B19V) structural protein or fragment thereof, and wherein the nonpermissive mammalian cell is a mammalian non-erythroid lineage cell. (patentsencyclopedia.com)
  • 43. The immunogenic composition of claim 42, further comprising a nucleic acid molecule encoding a parvovirus B19 (B19V) structural protein or fragment thereof, wherein the codons of the nucleic acid molecule are optimized for expression in a mammalian non-erythroid lineage cell. (patentsencyclopedia.com)
  • Parvovirus particles (virions) have a durable non-enveloped protein capsid ~20-30 nm in diameter that contains a single copy of the linear single-stranded ~ 5kb DNA genome, which terminates in small imperfect palindromes that fold into dynamic hairpin telomeres. (wikipedia.org)
  • causes
  • Some causes of vomiting are easily treated, such as when a pet with an allergy to a certain food stops Click here to learn one way your vet may manage vomiting in dogs '}">vomiting when the diet is switched. (vetstreet.com)