• NCI scientists found that tumors of germ-free mice (mice completely lacking these microorganisms), or mice treated with antibiotics to deplete the gut of bacteria, were largely impaired in their ability to respond to immunotherapy that slows cancer growth and prolongs survival. (nih.gov)
  • To analyze tumors at comparable stages of progression, lymphoma, colon, and melanoma cancers that could be transplanted were selected, based on their susceptibility to therapeutic drugs. (nih.gov)
  • Cancer cells from these tumors were then injected under the skin of the mice, where they formed tumors that grew to reach a diameter of one-fifth of an inch or more. (nih.gov)
  • To report the treatment outcomes of patients with sinonasal neuroendocrine tumors who were treated with a combination of surgery, radiation therapy, and/or chemotherapy at the Mayo Clinic in Arizona. (cancernetwork.com)
  • RefleXion is a privately-held company developing the first biology-guided radiotherapy system, a significant change in strategy from single tumor therapy to the ability to one day treat multiple tumors in the same treatment session in cancers that have metastasized. (biospace.com)
  • The second project will use DNA sequencing and subsequent bioinformatics analysis to better understand how prostate cancer tumors evolve and metastasize to kill patients. (uclahealth.org)
  • We hope to use this opportunity to better understand what makes prostate cancer tumors spread," said Dr. Boutros. (uclahealth.org)
  • The concept of the immune tumor micro-environment's role in influencing breast cancer biology has resurfaced after the recognition that expression of genes associated with stromal (fibroblast) and immune (macrophage, T-cell) components significantly contribute to the global gene expression landscape within the breast tumors as detected by the use of cDNA based gene expression microarrays [7]. (heraldopenaccess.us)
  • 50%) in tumors of women with operable, triple negative breast cancer enrolled in a large adjuvant chemotherapy trial BIG 2-98, was strongly associated with favorable disease free (p=0.014) and overall (p=0.029) survival [11]. (heraldopenaccess.us)
  • Material and methods: Data on tumors, treatment and outcomes in patients with BOTSCC treated between 2008 and 2014 were validated through medical records and updated as needed. (lu.se)
  • An increase in OS was found with the addition of CT to EBRT for patients with p16+ tumors, stages II-III, but for patients with tumor stage I, p16+ (UICC 8) none of the treatment strategies was superior to EBRT alone. (lu.se)
  • In the small group of patients with p16− tumors, a poorer prognosis was found, but the small sample size did not allow any comparisons between different treatment strategies. (lu.se)
  • We compare clinical characteristics of prostate cancer tumors diagnosed within WTCHP with those characteristics of an age-matched group of prostate cancers who are not related to WTC. (cdc.gov)
  • A review of the literature by Koontz et al showed that radiation alone may be the optimal treatment in early-stage tumors involving only the distal urethra. (medscape.com)
  • Gene expression profiling of tumors using DNA microarrays is a promising method for predicting prognosis and treatment response in cancer patients. (lu.se)
  • 7] there primary breast tumors could be used to predict disease is an evident correlation between clinical outcome for the recurrence better than currently available clinical and patients and ER- status of the tumors. (lu.se)
  • Investigators report a trend in overall survival improvement among patients with advanced/recurrent endometrial cancer treated with atezolizumab and chemotherapy. (cancernetwork.com)
  • Results from the phase 3 GCIG INTERLACE trial highlight progression-free survival and overall survival improvements with induction chemotherapy plus chemoradiotherapy for patients with locally advanced cervical cancer. (cancernetwork.com)
  • Daily online exclusives cover late breaking oncology news, safe handling and administration of chemotherapy drugs, side effect management, and new developments in specific cancers. (oncologynurseadvisor.com)
  • 3]] Previous research has revealed ethnic disparity in cancer treatment-for instance, Māori with breast cancer are less likely to receive radiotherapy or long-term adjuvant endocrine therapy,[[5]] and Māori with colorectal cancer are less likely to receive chemotherapy. (nzma.org.nz)
  • hence, we sought to investigate possible differences in the use of systemic anti-cancer chemotherapy (SACT) in Māori and non-Māori. (nzma.org.nz)
  • And what salvage surgery is basically when people fail their primary treatment, whether that be initial surgery or initial radiation or a combination of surgery and radiation or radiation and chemotherapy and their cancers either persist, don't go away or they come back, they're oftentimes left with typically one option and that's surgery to try and what we call salvage or kind of rescue them from their disease. (clevelandclinic.org)
  • There is no definitive conclusion so far on the predictive values of ERCC1 polymorphisms for clinical outcomes of platinum-based chemotherapy in non-small cell lung cancer (NSCLC). (hindawi.com)
  • Consequently, it is necessary to identify functional gene polymorphisms as new biomarkers for accurately predicting clinical outcomes of chemotherapy in NSCLC, which could also reduce the side effects and provide the most cost-effective approach for individuals [ 3 , 4 ]. (hindawi.com)
  • This study shows the use of the antioxidants vitamin C and vitamin E during and after treatment with chemotherapy has a statistically significant impact on both mortality and risk of recurrence. (naturalmedicinejournal.com)
  • The use of radiotherapy, surgery and chemotherapy in the curative treatment of cancer: results from the FORTY (Favourable Outcomes from RadioTherapY) project. (bvsalud.org)
  • Radiotherapy , surgery and chemotherapy play key roles in the curative treatment of cancer , alone and in combination. (bvsalud.org)
  • We analysed patient -level data on utilisation of surgery , radiotherapy , and chemotherapy in cancer patients in England . (bvsalud.org)
  • Two in 10 cancer patients (20%) surveyed were able to avoid unnecessary chemotherapy and/or radiation and 10% became eligible for a clinical trial. (hrnewswire.com)
  • Radiotherapy (EBRT) ± concomitant chemotherapy (CT) is the backbone of the curatively intended treatment, with brachytherapy (BT) boost as an option. (lu.se)
  • Radiation therapy has several roles in the management of urethral cancer, including use as primary therapy, in combination with chemotherapy and/or surgery, or as adjuvant treatment for local recurrence after surgery. (medscape.com)
  • Limited data exist regarding the role of chemotherapy in urethral cancer treatment. (medscape.com)
  • Combination chemotherapy with methotrexate , vinblastine , doxorubicin , and cisplatin (MVAC) or cisplatin, methotrexate, and vinblastine (CMV) regimens have shown survival benefit in the treatment of transitional-cell bladder cancer and have become the regimens of choice for metastatic urothelial cancer. (medscape.com)
  • A new drug for renal cell carcinoma slowed the growth of advanced kidney cancer in patients who became resistant to the first-line therapies that had previously kept it in check, according to results from a clinical trial. (sciencedaily.com)
  • A new drug has been found superior to current treatments in slowing the growth of advanced kidney cancer in patients who became resistant to the first-line therapies that had kept it in check, according to results from a clinical trial led by Dana-Farber Cancer Institute. (sciencedaily.com)
  • Cabozantinib controlled the cancer in the drug-resistant patients more effectively than everolimus. (sciencedaily.com)
  • Moreover, the early results show a "strong trend indicating that survival may be improved in patients receiving cabozantinib compared to standard therapy," said Toni K. Choueiri, MD, clinical director of the Genitourinary Cancer Treatment Center at Dana-Farber Cancer Institute, the first author of the report. (sciencedaily.com)
  • Renal cell carcinoma is the most common form of kidney cancer, diagnosed annually in more than 330,000 patients worldwide and causing over 140,000 deaths. (sciencedaily.com)
  • The multi-center trial enrolled 658 patients with clear cell renal carcinoma, which makes up over 80 percent of people with kidney cancer. (sciencedaily.com)
  • Dec. 22, 2022 A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. (sciencedaily.com)
  • We therefore aimed to analyze the outcome of IIP patients with LC under different treatment modalities. (nih.gov)
  • Significant treatment-related toxicities occurred in 55% IPF, 20% NSIP und 0% COP patients. (nih.gov)
  • The National Cancer Institute (NCI) leads the National Cancer Program and the NIH effort to dramatically reduce cancer and improve the lives of cancer patients and their families, through research into prevention and cancer biology, the development of new interventions, and the training and mentoring of new researchers. (nih.gov)
  • Findings from the phase 2 SKYSCRAPER-04 trial support dual targeting of TIGIT and PD-L1 in patients with PD-L1-positive cervical cancer, says Ritu Salani, MD. (cancernetwork.com)
  • This Funding Opportunity Announcement (FOA) encourages collaborative applications that will contribute to the identification and characterization of patients at risk of developing cancer treatment-related cardiotoxicity. (nih.gov)
  • The purpose of this Funding Opportunity Announcement (FOA) is to stimulate collaborative applications that will contribute to the identification and characterization of patients at risk of developing cancer treatment-related cardiotoxicity with the primary intent to mitigate cardiovascular dysfunction while optimizing cancer outcomes. (nih.gov)
  • Your gift will help support our mission to end cancer and make a difference in the lives of our patients. (mdanderson.org)
  • A team of researchers from across five disciplines at MD Anderson recently published the largest prospective study on breast implant associated anaplastic large cell lymphoma (BIA-ALCL), shedding light on the best treatment for patients with this uncommon cancer. (mdanderson.org)
  • The single-cell functional precision medicine treatment, an artificial intelligence strategy helps to create therapies for patients with hematologic cancers. (cancernetwork.com)
  • Results from the EXALT-1 study highlighted the potential real-world impact of utilizing an artificial intelligence (AI)-supported precision medicine platform to determine the most effective therapies for patients with late-stage hematological cancers, according to a press release from Exscientia. (cancernetwork.com)
  • The study evaluated 76 patients, 56 of whom received treatment according to scFPM and 20 were treated according to physician's choice. (cancernetwork.com)
  • Patients had a median age of 64 years, and the median number of treatment lines prior to enrollment was 3. (cancernetwork.com)
  • After 12 months on treatment, 23% of patients were progression free compared with 5% on the previous treatment. (cancernetwork.com)
  • Patients had an objective response rate of 55% among those whose treatment was guided with scFPM as well as 60% for the lymphoid subgroup and 41% for myeloid neoplasms. (cancernetwork.com)
  • The PREMIER registry was created to collect data to demonstrate the impact of the RefleXion® X1 radiotherapy system, the first-ever system with onboard fast fan-beam KVCT, on patients with all solid tumor and lymphoma cancer types. (biospace.com)
  • The PREMIER registry will assess health-related quality of life, acute and long-term side effects in patients, and cancer-related outcomes. (biospace.com)
  • Our hope is that collecting this rich repository of information before, during, and after treatment will enable our clinical partners to investigate and identify the factors that best determine cancer outcomes, which may then arm patients with the information they need to make better decisions around their care. (biospace.com)
  • Deanna Glassman, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues used pretreatment laparoscopic surgical videos (435 still-frame images) of 113 patients with pathologically proven HGSOC (2013 to 2019) to train an AI model utilizing deep learning and neural networks. (physiciansweekly.com)
  • The model was used to identify trends in morphologic patterns between patients with an excellent response to standard treatment (defined as progression-free survival of at least 12 months) and those with a poor response to therapy (defined as progression-free survival of no more than six months). (physiciansweekly.com)
  • This pilot study is an exciting frontier in surgical innovation that shows how we can use machine learning to enhance our clinical approach to treating patients with gynecologic cancers," Glassman said in a statement. (physiciansweekly.com)
  • A retrospective comparison demonstrated that in persons with stage I non-small cell lung cancer (NSCLC), overall survival was superior among patients undergoing lobectomy or pneumonectomy compared with patients undergoing stereotactic body radiation therapy (SBRT), but cancer-specific survival rates were similar between the two groups. (oncologynurseadvisor.com)
  • HRs for time to metastasis or death as a result of PCa were compared between patients who deferred treatment and those who underwent immediate treatment within 1 year of diagnosis. (harvard.edu)
  • Factors associated with progression to treatment among DT patients included younger age, higher clinical stage, higher Gleason score, and higher prostate-specific antigen at diagnosis. (harvard.edu)
  • PCa mortality did not differ between DT and active treatment patients. (harvard.edu)
  • A model based on artificial intelligence is able to predict the therapy outcome (measured by volumetric reduction of tumor lesions) in 80% of ovarian cancer patients. (technologynetworks.com)
  • This achievement stems from a recent study published in Nature Communications , conducted on 134 high-grade ovarian cancer patients. (technologynetworks.com)
  • Ovarian cancer affects over five thousand women annually in Italy, adding to the thirty thousand patients who have already received a diagnosis. (technologynetworks.com)
  • For all patients clinicians collected clinical data, including demographic information and treatment details, as well as blood biomarkers like CA-125 and circulating tumor DNA (ctDNA). (technologynetworks.com)
  • 1]] Most patients with non-small cell lung cancer (NSCLC) will have advanced disease at diagnosis. (nzma.org.nz)
  • We excluded patients enrolled in clinical trials (22) and patients with epidermal growth factor receptor (EGFR) mutated lung cancer (95). (nzma.org.nz)
  • We reviewed the characteristics and SACT regimens of lung cancer patients with advanced NSCLC. (nzma.org.nz)
  • Using the Kaplan-Meier method, we calculated all-cause survival after diagnosis of lung cancer for patients with and without SACT by ethnicity. (nzma.org.nz)
  • After excluding trial patients (22) and those with EGFR-mutated lung cancer (95), we identified 1,057 cases who had been referred to oncology with advanced-stage NSCLC. (nzma.org.nz)
  • The proportion of referred patients receiving treatment increased from 49% (65/133) in 2000-2004 to 55% (222/401) in 2015-2021 (Table 1). (nzma.org.nz)
  • So, I was putting a talk together 2018 for that on salvage surgery for head and neck cancer patients. (clevelandclinic.org)
  • Some patients show significant tumor regression while others may develop intrinsic or acquired resistance to chemical drugs, which highlights the need to tailor the treatment for individuals [ 3 ]. (hindawi.com)
  • Pharmacogenomics has been perceived as a useful tool to predict treatment response as well as clinical prognosis in cancer patients, and numerous studies have suggested the functions of single nucleotide polymorphisms (SNPs) in affecting drug sensitivity by modifying relevant genes [ 4 ]. (hindawi.com)
  • Section 100 (Highly Specialised Drugs Program) listing for treatment of patients under 18 years who have severe polyarticular course juvenile chronic arthritis who meet certain criteria. (pbs.gov.au)
  • Purpose: There exists a subgroup of patients with head and neck cancer (HNC) who neither warrant nor request curative-intent treatment and who progress to a terminal-care paradigm. (edu.au)
  • Nasopharyngeal cancer patients are frequently given medications that stimulate their immune systems to attack the tumor. (proclaimerscv.com)
  • According to the study, patients who received the Sinovac vaccine from China did better with cancer medications than those who did not. (proclaimerscv.com)
  • Over 1,500 patients from 23 hospitals across China who were receiving treatment there took part in the study. (proclaimerscv.com)
  • 72 (76.6%) patients received planned adjuvant treatment. (bmj.com)
  • 1 Antibiotics play a detrimental role on outcomes in patients on ICIs. (bmj.com)
  • Huang L, Chen X, Zhou L, Xu Q, Xie J, Zhan P, Lv T, Song Y. Antibiotic exposure windows and the efficacy of immune checkpoint blockers in patients with cancer: a meta-analysis. (bmj.com)
  • Conclusion Ga-68-PSMA-PET/CT-based MDT is an efficient and safe treatment for oligometastatic PC patients. (uludag.edu.tr)
  • The company has developed an autologous CAR T-cell therapy candidate to treat cancer patients. (rssl.com)
  • These patients were offered the opportunity to try a different treatment. (axisimagingnews.com)
  • The estimate that 40% of cancer patients are cured by RT has been used extensively to inform and influence policy but is relatively old and warrants review . (bvsalud.org)
  • Radiotherapy was delivered to almost 40% of patients who survived 5 years which underlines its importance in cancer management. (bvsalud.org)
  • According to a new survey released today by Cancer Care , a leading national cancer support organization, biomarker testing helped doctors tailor therapy for nearly all the respondent patients (93%) whose cancers were tested over the past three years. (hrnewswire.com)
  • Unfortunately, health insurance plans often limit cancer patients' access to recommended biomarker testing, impose burdensome prior authorization protocols, or require unaffordable cost-sharing, which can prevent or delay cancer patients' access to optimal treatments. (hrnewswire.com)
  • Prior authorization , a significant source of roadblocks to timely testing and treatment, was required by a quarter (25%) of the cancer patients surveyed . (hrnewswire.com)
  • Biomarker testing has been proven to be extremely valuable in identifying the most effective therapy for eligible cancer patients because it helps them receive the right treatments at the right time while also saving money and leading to better outcomes. (hrnewswire.com)
  • Eleven states have enacted or are about to enact legislation mandating that health plans cover biomarker testing for cancer patients. (hrnewswire.com)
  • Research published by the American Society of Clinical Oncology shows significant gaps in the rate of biomarker testing between Black and white lung and colorectal cancer patients, which can lead to disparities in clinical trial participation and hinder access to the most effective treatments. (hrnewswire.com)
  • This precision targeting results in drugs that can be more effective and have fewer side effects for patients than traditional radiation treatments. (ubc.ca)
  • We founded this company to turn the research we were doing at UBC and BC Cancer into treatments that will help patients thrive and, ultimately, save lives," says Dr. François Bénard, one of the company's co-founders, and a radiology professor at UBC's faculty of medicine and senior executive director of the BC Cancer Research Institute. (ubc.ca)
  • This new financing will further accelerate development, bringing new cancer treatments to patients faster. (ubc.ca)
  • According to Dr. David Hirsch, chief executive officer of Alpha-9, the $75 million in Series B financing will enable the company to bring its first five treatments into clinical trials with patients over the next two years. (ubc.ca)
  • We founded this company to turn the research we were doing at UBC and BC Cancer into treatments that will help patients thrive and, ultimately, save lives. (ubc.ca)
  • To measure patients' perceptions of patient centredness and the relation of these perceptions to outcomes. (bmj.com)
  • Components of patients' perceptions can be measured reliably and predict different outcomes. (bmj.com)
  • Tumor infiltrating lymphocytes are studied for their potential as new clinically useful prognostic and predictive biomarkers in patients with triple negative and HER-2/neu amplified breast cancer. (heraldopenaccess.us)
  • No association was found between TIL levels and outcomes of patients with hormone receptor positive or HER-2/neu amplified breast cancer. (heraldopenaccess.us)
  • Results: Treatment was EBRT, EBRT + CT, EBRT + BT or EBRT + CT + BT in 151, 145, 82 and 167 patients respectively (n = 545). (lu.se)
  • An increase in survival was found for EBRT + CT compared to EBRT alone in patients with advanced cases, stages II and III (UICC 8), but none of the regimes was significantly superior to EBRT as a single treatment modality for stage I (UICC 8), provided there was p16 positivity in the tumor. (lu.se)
  • To investigate markers of inflammation in prostate cancer samples from WTCHP patients and matched prostate cancers not related to WTC. (cdc.gov)
  • We will analyze immunohistochemical and molecular markers of inflammation in archival prostate cancer samples from WTCHP patients, and matched controls. (cdc.gov)
  • To compare DNA methylation as a marker of tumor aggressiveness in WTCHP prostate cancer patients and in matched prostate cancers not related to WTC. (cdc.gov)
  • We will analyze DNA methylation in prostate tissue samples from WTCHP patients and from a group of age and stage matched prostate cancers not related to WTC. (cdc.gov)
  • A further study by Dalbagni et al (1999) offered radiation treatment to 6 patients, but none responded. (medscape.com)
  • [ 9 ] This outcome may be the result of selection bias because all 6 patients had T3 or higher lesions. (medscape.com)
  • Most recently, she and her team at NCI helped launch a nationwide screening trial for breast cancer patients. (medlineplus.gov)
  • Clinical outcome for the patients is represented by M+ (distant recurrences within 6 years) and M- (no recurrences within a follow-up vised clustering was into two groups based on ER- period of at least 5 years). (lu.se)
  • This resulted in a lower production of cytokines (proteins secreted by lymph cells that affects cellular activity and controls inflammation) as well as lower tumor death therefore demonstrating that optimal responses to cancer therapy required an intact commensal microbiota. (nih.gov)
  • Our prospective registry will capture and organize an unprecedented level of data including patient, demographic, tumor, biomarker, imaging and treatment information for all stages of cancer," said Sean Shirvani , M.D., MPH, chief medical officer at RefleXion. (biospace.com)
  • These data suggest a predictable impact of specific constituents of the microbiota on tumor growth and cancer treatment outcomes with implications for both prognosis and therapy. (leibniz-hki.de)
  • Over the recent years, new results from multiple groups have pointed towards Tumor Infiltrating Lymphocytes (TILs) as prognostic and predictive biomarkers in breast cancer. (heraldopenaccess.us)
  • However, over the next several decades, a number of studies examined the association between tumor lymphocytic infiltrates and prognosis in more common histologic types of breast cancer and yielded contradictory results [3-6]. (heraldopenaccess.us)
  • In the recently presented confirmatory study, tumor samples of women with operable triple negative breast cancer from two large adjuvant trials (ECOG 2197 and ECOG 1199) were analyzed for the presence of TILs [12]. (heraldopenaccess.us)
  • We aim to look at survival outcomes of advanced-stage carcinoma endometrium, managed through surgery and adjuvant treatment. (bmj.com)
  • Personalized dosing allowed one-third of the men in this study to have treatment breaks while still achieving the same progression-free and overall survival outcomes they would have if they received continuous treatment," notes Nguyen. (axisimagingnews.com)
  • Patient , tumour and treatment event data was obtained for the 5 year period from 2009 to 2013, allowing a further 5 years for survival outcomes to be known. (bvsalud.org)
  • Breast implant associated anaplastic large cell lymphoma is classified as an uncommon cancer by the FDA. (mdanderson.org)
  • Alpha-9's radiopharmaceuticals are designed to treat a range of solid and hematologic cancers such as prostate cancer, breast cancer, leukemia and lymphoma. (ubc.ca)
  • With this approach, we aim to bolster the role of primary health care services to help avert excess mortality of African women from preventable cancers," said Dr Matshidiso Moeti, WHO Regional Director for Africa. (who.int)
  • In Qatar, that may lead to cervical cancer, knew most preventable cancers [2]. (who.int)
  • Advancements in basic science research are being translated for improving gastric cancer patient care. (novapublishers.com)
  • Experts from University of California, Los Angeles Health and Mayo Clinic discuss key data presented at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting in the gynecologic and gastrointestinal cancer spaces and how they may impact patient care. (cancernetwork.com)
  • The platform utilizes AI technology to perform a single cell, high content analysis of individual patient tissue samples in order to garner clinically important insights upon which treatments can be based. (cancernetwork.com)
  • Prospective registries define specific information and characteristics in advance, before data collection or the impacts of a treatment are known, including the check-in interval for patient follow-up. (biospace.com)
  • The first aims to centralize prostate cancer DNA sequencing data from around the country, then use bioinformatics computing pipelines developed by Dr. Boutros's lab to identify which genes are mutated repeatedly in prostate cancer to create biomarkers and ultimately optimize patient treatment. (uclahealth.org)
  • Additionally, there are few clinically useful biomarkers for this type of cancer due to its high heterogeneity, varying significantly from patient to patient. (technologynetworks.com)
  • After adjusting for certain factors including age of patient at time of treatment, cause of female or male infertility, and type of treatment (ICSI vs IVF), the study found that White Irish, South Asian Indian, South Asian Bangladeshi, South Asian Pakistani, Black African, and Other Asian women had a significantly lower odds of a live birth than White British women. (nottingham.ac.uk)
  • Conclusion: This study serves as a timely reminder that when curative-intent HNC treatment options have been exhausted, dialog and action need to be directed to transitioning the patient to a terminal-care management paradigm. (edu.au)
  • Proper patient selection might improve treatment outcomes. (uludag.edu.tr)
  • By monitoring early-response biomarkers in men undergoing 177 Lu-PSMA prostate cancer treatment, physicians can personalize dosing intervals, significantly improving patient outcomes. (axisimagingnews.com)
  • However, monitoring early-response biomarkers to adjust treatment intervals may improve patient outcomes. (axisimagingnews.com)
  • Purpose The first aim of this study was to assess plan quality using a conformity index (CI) and analyse its influence on patient outcome. (cardiff.ac.uk)
  • A systematic review of 21 studies found that better communication improved outcomes, although most studies didn't specifically assess the patient centred model and a minority were from general practice. (bmj.com)
  • We are the UK's largest and most active patient-led kidney cancer charity. (actionkidneycancer.org)
  • Whether you are a patient, survivor or someone you know has been diagnosed with kidney cancer, you have come to the right place to find support and information, and to be part of a caring and knowledgeable community of people: We are here to help you. (actionkidneycancer.org)
  • The study will generate novel data on biomarkers of prostate cancer aggressiveness that could be used to make decisions on clinical treatment. (cdc.gov)
  • Surgical resection remains the mainstay of curative treatment. (gla.ac.uk)
  • One of the reasons I came to NCI as a breast oncologist was to be able to look at racial disparities and see the differences in risk, screening, treatment, and survivorship. (medlineplus.gov)
  • Idiopathic interstitial pneumonias (IIP) are associated with an increased lung cancer (LC) risk. (nih.gov)
  • My research involves the redesign of the web-based software for predicting lung cancer treatment outcomes. (eventscloud.com)
  • Still, prostate cancer remains the second leading cause of cancer death in American men, behind only lung cancer. (uclahealth.org)
  • Lung cancer is the commonest cause of cancer death in Aotearoa New Zealand. (nzma.org.nz)
  • 2,3]] Indeed, the 5-year overall survival for lung cancer across all stages in Aotearoa New Zealand in 2014 was only 15.5%, with just a 4% improvement from 1999. (nzma.org.nz)
  • 4]] Of particular concern has been the finding that Māori, the Indigenous people of Aotearoa New Zealand , have a 30% greater mortality from lung cancer compared to non-Māori. (nzma.org.nz)
  • We collected information on the following variables: age, gender, ethnicity (Māori or non-Māori), date/year of lung cancer diagnosis, stage at diagnosis, SACT regimens prescribed and survival. (nzma.org.nz)
  • Lung cancer is currently the most common human malignancies and the leading cause of cancer-related mortality in the world. (hindawi.com)
  • Non-small cell lung cancer (NSCLC) accounts for ~85% of all lung cancer cases, with 30% being squamous cell carcinoma (SCC) and the remaining (~70%) being collectively classified as non-SCC [ 1 ]. (hindawi.com)
  • Oral gavage of these responder bacteria significantly increased the efficacy of erlotinib and induced the expression of CXCL9 and IFN-γ in a murine lung cancer model. (leibniz-hki.de)
  • The effect of antibiotic use (from 8 weeks before to 4 weeks after the start of treatment) on progression -free survival and overall survival was evaluated. (actionkidneycancer.org)
  • Purpose: To examine consequences of deferred treatment (DT) as initial management of prostate cancer (PCa) in a contemporary, prospective cohort of American men diagnosed with PCa. (harvard.edu)
  • Results: From among 3,331 cohort participants diagnosed with PCa from 1986 to 2007, 342 (10.3%) initially deferred treatment. (harvard.edu)
  • P = .99) for DT and immediate treatment, respectively.ConclusionIn this nationwide cohort, more than half the men who opted for DT remained without treatment for 7.7 years after diagnosis. (harvard.edu)
  • Vitamin supplement use during breast cancer treatment and survival: a prospective cohort study. (naturalmedicinejournal.com)
  • Population-based prospective cohort study of women with invasive breast cancer in Shanghai, China, between 2002-2006. (naturalmedicinejournal.com)
  • Here, we investigated the contribution of the intestinal microbiome on treatment outcomes in a heterogeneous cohort that included multiple cancer types to identify microbes with a global impact on immune response. (leibniz-hki.de)
  • A machine-learning model was developed and validated in an independent cohort to predict treatment outcomes based on gut microbiota composition and functional repertoires of responders and non-responders. (leibniz-hki.de)
  • Prostate cancer characteristics in the World Trade Center cohort, 2002-2013. (cdc.gov)
  • The registry will expand to include BgRT procedures, a new radiotherapy treatment modality that uses signals detected from positron emission tomography (PET) to guide radiotherapy. (biospace.com)
  • Data were sourced from Public Health England , using National Cancer Registrations, the National Radiotherapy Dataset (RTDS) and the Systemic Anti- Cancer Therapy Dataset (SACT). (bvsalud.org)
  • Radiotherapy as a primary mode of treatment has been suggested to be equivalent to surgery in the setting of small early-stage lesions. (medscape.com)
  • In women, radiotherapy is increasingly being used as a primary treatment because of the increased morbidity associated with surgical management. (medscape.com)
  • MRI-Only Radiotherapy of Prostate Cancer. (lu.se)
  • FRIDAY, March 25, 2022 (HealthDay News) - An artificial intelligence (AI) model may help predict clinical outcomes at the time of laparoscopic assessment for advanced high-grade serous ovarian cancer (HGSOC), according to a study presented at the Society of Gynecologic Oncology's Annual Meeting on Women's Cancer, held from March 18 to 21 in Phoenix. (physiciansweekly.com)
  • Approved by the U.S. FDA in 2022, 177 Lu-PSMA is an effective treatment for metastatic castration-resistant prostate cancer. (axisimagingnews.com)
  • Colorectal cancer (CRC) screening rates are low in New Mexico. (cdc.gov)
  • Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer in New Mexico and the second leading cause of cancer death (1). (cdc.gov)
  • Internationally, cervical cancer has It has been demonstrated that the vast ing items: whether the respondent had been regarded as the third most com- majority of women in some African ever heard of cervical cancer, had ever mon form of cancer among women countries had not heard of cervical can- heard that Pap smear is used to detect after breast and colorectal cancer [1]. (who.int)
  • Experts from UCLA Health discuss key data presented at The Society of Gynecologic Oncology 2023 Annual Meeting on Women's Cancer and how they may apply to clinical practice. (cancernetwork.com)
  • The outcomes of the research, which was carried out by the Universities of Bonn and Shanxi in the People's Republic of China, are released as a "Letter to the editor" in the Annals of Oncology journal but are already published online. (proclaimerscv.com)
  • All Cancer Care services are provided by master's-prepared oncology social workers and world-leading cancer experts. (hrnewswire.com)
  • In a study presented at the Society of Nuclear Medicine and Molecular Imaging 2023 Annual Meeting, early stratification with 177 Lu-SPECT/CT allowed men responding to treatment to take a "treatment holiday" and allowed those not responding the option to switch to another treatment. (axisimagingnews.com)
  • NEW YORK , April 13, 2023 /PRNewswire/ - Biomarker testing is a necessary tool in the advancing world of precision cancer treatment. (hrnewswire.com)
  • Objectives To explore community knowledge, facilitators and barriers to cervical cancer screening among women in rural Uganda so as to generate data to inform interventions. (bmj.com)
  • Results Study participants' knowledge about cervical cancer causes, signs and symptoms, testing methods and prevention was poor. (bmj.com)
  • Many participants attributed the cause of cervical cancer to use of contraception while key informants said that some believed it was due to witchcraft. (bmj.com)
  • Perceptions towards cervical cancer and screening were majorly positive with many participants stating that they were at risk of getting cervical cancer. (bmj.com)
  • The facilitators to accessing cervical cancer screening were: experiencing signs and symptoms of cervical cancer, family history of the disease and awareness of the disease/screening service. (bmj.com)
  • Lack of knowledge about cervical cancer and screening, health system challenges, fear of test outcome and consequences and financial constraints were barriers to cervical cancer screening. (bmj.com)
  • Conclusion Whereas perceptions towards cervical cancer and screening were positive, knowledge of study participants on cervical cancer was poor. (bmj.com)
  • To improve cervical cancer screening, effort should be focused on reducing identified barriers and enhancing facilitators. (bmj.com)
  • Study findings have the potential to influence design of future cervical cancer programmes and services. (bmj.com)
  • Globally, in 2012, cervical cancer was responsible for 265 700 deaths and 527 600 diagnoses, 85% of which occurred in developing countries. (bmj.com)
  • 1 2 Estimates for Uganda show that cervical cancer led to 2300 deaths and 4000 new cases in 2012. (bmj.com)
  • Cervical cancer screening rates in Uganda are very low despite the higher intention and willingness to screen. (bmj.com)
  • Brazzaville/New York - An initiative to support better access to breast and cervical cancer detection, treatment and care services is being piloted in three African countries. (who.int)
  • Breast and cervical cancer currently constitute over half the cancer burden for women in sub-Saharan Africa. (who.int)
  • In addition, early detection services will be integrated into existing cervical cancer screening clinics to ensure both old and new systems are unified. (who.int)
  • The aim is to provide an integrated and holistic system of health care that will contribute to addressing the burden of breast and cervical cancer in the African region. (who.int)
  • A 2019 British Medical Journal analysis determined that only about 2% of official bilateral and multilateral development aid is targeted at noncommunicable diseases, including breast and cervical cancer, The African region accounts for only 1% of world health expenditure, despite having 24% of the global disease burden, according to a 2019 report by the University of Washington's Institute for Health Metrics and Evaluation. (who.int)
  • Despite being preventable and curable through screening and human papillomavirus (HPV) vaccination, cervical cancer remains the most common cause of all cancer-related deaths in African countries. (who.int)
  • Together with partners, WHO is supporting countries to scale up screening, early detection treatment and care of breast and cervical cancers among women in sub-Saharan Africa. (who.int)
  • Therefore this cross-sectional interview-based study was conducted in 2008 among 500 women at 5 randomly selected primary health care centres in Qatar to determine their knowledge, attitude and practices regarding cervical cancer and screening. (who.int)
  • Just over 85% had heard of cervical cancer and 76% had heard about the Pap smear. (who.int)
  • developing countries, women's knowl- and beliefs about cervical cancer and edge of cervical cancer is very limited. (who.int)
  • Popu- where cervical cancer is responsible for the early detection of cervical cancer lation-based cervical smear screening 50% of diagnosed gynaecological can- leads to better treatment and whether programmes for cervical cancer have cers [13], there is no previous study that is it possible to cure this cancer. (who.int)
  • The risk and practices regarding cervical cancer with the following items: whether they factors for cervical cancer include early among females of reproductive age. (who.int)
  • A male consort who tion concerning knowledge, attitude a simple, painless procedure and could in turn has had intercourse with mul- and practices towards cervical cancer lead to early detection and treatment tiple women and smoking also confer and the Pap smear test. (who.int)
  • Primary outcomes included objective response rate (ORR), progression-free survival (PFS), and overall survival (OS). (hindawi.com)
  • The primary endpoints for the study were time to treatment failure (TTF) and overall survival (OS). (bmj.com)
  • It has been demonstrated, and our present study has confirmed, that after antibiotic treatment the bacterial composition in the gut never returns to its initial composition," said Trinchieri. (nih.gov)
  • 2 Despite this association, there's limited evaluation on antibiotic subclasses and outcomes. (bmj.com)
  • The main end point is progression-free survival -- how long the cancer is held in check before it starts growing again. (sciencedaily.com)
  • They hope to better understand whether 3D mammography is better at diagnosing advanced breast cancers than the current 2D technology. (medlineplus.gov)
  • It was recently reported that expression profiles of sporadic breast cancers could be used to predict disease recurrence better than currently available clinical and histopathological prognostic factors. (lu.se)
  • This emphasizes that a good prognosis is dependent on appropriate diagnosis and a standardized multi-team treatment approach. (mdanderson.org)
  • For instance, it has been known since 1940s that a subtype of breast cancer that characteristically exhibits a very large proportion of stromal lymphocytic infiltrate, called medullary carcinoma, has been associated with excellent prognosis after aggressive local therapy in spite of high histologic grade and axillary lymph node metastases [1,2]. (heraldopenaccess.us)
  • High expression of genes typical for lymphocytes (such as CD8) and low expression of genes typical of myeloid cells (such as CD68) was found to indicate better prognosis, especially in basal like and HER-2/neu positive breast cancer subtypes [8-10]. (heraldopenaccess.us)
  • This has generated a renewed excitement and multiple investigators began to study the potential association between TILs, prognosis and response to systemic therapy for breast cancer. (heraldopenaccess.us)
  • They come into treatment very late in the disease, and their rate of aggressive, triple-negative breast cancer-the subtype with the poorest prognosis-is higher than in other racial groups. (medlineplus.gov)
  • Because of the rarity of this pathology and the lack of statistical analysis on the data, no consensus has been reached on treatment modalities. (medscape.com)
  • Is the Subject Area "Cancers and neoplasms" applicable to this article? (plos.org)
  • Research applications should focus on mitigation/management of adverse effects associated with anti-cancer treatments including: cytotoxic chemotherapies, targeted agents, immunomodulatory therapies and radiation (that occur during cancer treatment and/or long-term survivorship) as defined by cardiac and/or vascular specific common terminology criteria for adverse events (CTCAE). (nih.gov)
  • However, there was no association seen in women who underwent radiation treatment (approximately one-third of participants). (naturalmedicinejournal.com)
  • Based on more than a decade of ground-breaking research at UBC and BC Cancer, the cancer drugs act like a homing device - seeking out tumours to deliver targeted radiation treatment, while having minimal impact on nearby healthy tissues. (ubc.ca)
  • health effects of nonionizing radiation, pesticides, drinking water treatment by-products, and perfluorinated compounds. (cdc.gov)
  • In addition, there appears to be some benefit in using radiation treatment over surgical therapy in women for both proximal and distal lesions because of the increased morbidity associated with surgery. (medscape.com)
  • At the National Cancer Institute (NCI), Dr. McCaskill-Stevens explores how race impacts cancer outcomes, especially in African American women, who are 40% more likely to die from breast cancer than white women. (medlineplus.gov)
  • This study aimed to investigate the association of the GSTP1 gene polymorphism with the outcomes and toxicities of treatments in breast cancer. (oncotarget.com)
  • 2016 Infectious Diseases Society of America (IDSA) clinical practice guideline for the treatment of coccidioidomycosis. (cdc.gov)
  • The transition from active cancer treatment into survivorship, known as re-entry , remains understudied. (cdc.gov)
  • Platinum combined with the third-generation cytotoxic drugs including gemcitabine and pemetrexed is the standard first-line treatment for advanced NSCLC [ 2 ]. (hindawi.com)
  • Gastric cancer is one of the leading causes of malignancy-related deaths worldwide with differences in incidence and treatment patterns geographically. (novapublishers.com)
  • This book discusses an extensive array of different topics on gastric cancer in which strides of improvement have been achieved. (novapublishers.com)
  • This book aims to bring the readers up to date about all aspects of gastric cancer - from basic science research about animal models of gastric cancer, to pathophysiology, staging systems, different adjuvant therapies and surgical treatment options for gastric cancer. (novapublishers.com)
  • The current statuses, debates and ongoing controversies in addition to the advancements on different aspects of gastric cancer research are discussed. (novapublishers.com)
  • The book is an invaluable resource of information on all aspects of gastric cancer with the latest advancements. (novapublishers.com)
  • Background: Gastric cancer is one of the leading causes of cancer-related deaths worldwide. (gla.ac.uk)
  • We report the outcomes at a single Australian centre. (gla.ac.uk)
  • Conclusion: This large Australian single centre study shows outcomes equivalent to other Western series and approaches that of Japanese data. (gla.ac.uk)
  • Waikato Hospital is the regional cancer centre for the central region of the North Island of Aotearoa New Zealand and provides care for approximately 800,000 people, of whom 30% identify as Māori. (nzma.org.nz)
  • Methods This was a retrospective study from a tertiary care cancer centre in India that included all women registered between 1st August 2011 and 31st January 2021 with operable advanced-stage carcinoma endometrium (stages 3 and 4). (bmj.com)
  • Plus de la moitié des femmes interrogées souhaitait que le test soit réalisé au centre de soins de santé primaires, en consultation gynécologique de dépistage. (who.int)
  • The primary intent is to mitigate cardiovascular dysfunction while optimizing cancer outcomes. (nih.gov)
  • When a cancer either persists or returns after a patient's primary treatment, salvage surgery provides another opportunity to remove the disease. (clevelandclinic.org)
  • I think people might be surprised how many different sub-sites and how many different primary locations one can unfortunately have head and neck cancer and it does require pretty complex reconstruction. (clevelandclinic.org)
  • The initiative in the three countries includes health promotion, screening, early diagnosis and treatment, as well as general primary care and screening for other noncommunicable diseases. (who.int)
  • The new initiative being rolled out in the three African countries will also seek to increase health care worker's ability to provide cancer care within communities through training and will supply and deliver the necessary equipment and essential supplies to support women at primary health care level. (who.int)
  • Treatment protocols for colon cancer are provided below, including adjuvant and neoadjuvant therapy for resectable disease and therapy for advanced or metastatic colon cancer. (medscape.com)
  • The study found that certain ethnic groups have significantly lower chances of live births using fertility treatments than other groups. (nottingham.ac.uk)
  • Peng Z, Cheng S, Kou Y, The Gut Microbiome Is Associated with Clinical Response to Anti-PD-1/PD-L1 Immunotherapy in Gastrointestinal Cancer. (bmj.com)
  • To accomplish this, methods that evaluate cardiovascular risk prior to treatment and integrate evidence-based cancer treatment regimens with cardiovascular screening, diagnostic, and/or management strategies are sought. (nih.gov)
  • Participants and Methods: We evaluated deferred treatment for PCa in the Health Professionals Follow-up Study, a prospective study of 51,529 men. (harvard.edu)
  • Therefore, we believe that it is neces- traditional histopathological methods, to improve diagno- sary to be cautious when interpreting the results from the sis, and to predict outcomes of disease [1-6]. (lu.se)
  • So, about half of my practice is removing cancers and the other half is reconstructing things after one of my partners removes the cancer. (clevelandclinic.org)
  • Thus, our findings raise the possibility that the frequent use of antibiotics during a patient's lifetime or to treat infections related to cancer and its side-effects may affect the success of anti-cancer therapy. (nih.gov)
  • Therefore, prospective registries can draw closer associations between the treatment delivered and a patient's outcome. (biospace.com)
  • The paper explores the possible reasons behind the variation and states that while genetic background could be a potential determinant of egg and sperm quality, variation in environmental exposures relating to lifestyle, dietary factors, socio-economic and cultural factors could be influencing egg and sperm quality, accessibility of fertility treatment and behaviour towards seeking medical care and consequently reproductive outcomes. (nottingham.ac.uk)
  • Dr Kanna Jayaprakasan, Associate Professor in Reproductive Medicine, University of Nottingham and Consultant subspecialist, Derby Fertility Unit, Royal Derby Hospital, senior author of the paper said: "The data suggests that ethnicity is a major independent factor determining the chances of IVF or ICSI treatment success. (nottingham.ac.uk)
  • Expertise: identifying and evaluating the beneficial and harmful effects of environmental chemicals, drugs, metals and other chemicals of concern so that strategies can be developed to prevent exposures to harmful agents or to develop disease prevention strategies for cancer, reproductive disease, and infectious diseases. (cdc.gov)
  • Background The gut microbiome can modulate therapeutic responses to immune checkpoint inhibitor (ICI) treatment in cancer. (bmj.com)
  • At the same time, Dr. Lin, a UBC radiology professor and senior scientist at BC Cancer, was developing new cancer-targeting peptides and working with Dr. Bénard to label them with therapeutic radioisotopes. (ubc.ca)
  • Leveraging a team science approach, the researchers began developing peptides that home in on cancer cells, and combining them with diagnostic radioisotopes for cancer localization and treatment planning, and with therapeutic radioisotopes to seek and eliminate cancer cells. (ubc.ca)
  • An intact population of microorganisms that derive food and benefit from other organisms living in the intestine is required for optimal response to cancer therapy, according to a mouse study by scientists at the National Cancer Institute (NCI), part of the National Institutes of Health, and their collaborators. (nih.gov)
  • This study underscores the critical importance of a standard treatment approach with a multi-team evaluation," says Mark Clemens, M.D. , the senior author of the study, which published in the Annals of Surgery . (mdanderson.org)
  • This study also demonstrated that with early diagnosis, better outcomes could be achieved. (mdanderson.org)
  • Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. (cdc.gov)
  • The study analysed fertility outcomes such as number of eggs retrieved, number fertilised, number of embryos created, implantation rate and live birth rate, which was the main outcome measure in the study. (nottingham.ac.uk)
  • This interesting study looking at maternal ethnicity provides useful data based on a large number of women undergoing fertility treatment. (nottingham.ac.uk)
  • Dr Patrick Chien, Consultant in Obstetrics & Gynaecology and Deputy Editor in Chief of BJOG said: "This study will be helpful for future treatment and could aid tailored treatment for women to maximise success rates. (nottingham.ac.uk)
  • The goal of our study is to determine what effect the spectrum of bacterial coverage or duration of therapy may have on ICI treatment. (bmj.com)
  • To date, there has been very little study of the use of multivitamins concurrent with treatment. (naturalmedicinejournal.com)
  • In an abstract presentation at the San Antonio Breast Conference in 2010, Dr. Jamie Matta presented a case-control study involving 268 women with recently diagnosed, untreated breast cancer and 457 controls. (naturalmedicinejournal.com)
  • Conversely, a study of 35,329 women, over a 10-year period, found a 19% increased risk of breast cancer in multivitamin users. (naturalmedicinejournal.com)
  • Purpose The aim of this study was to evaluate the outcomes of(68)Ga prostate-specific membrane antigen (Ga-68-PSMA) positron-emission tomography (PET)/CT-based metastasis-directed treatment (MDT) for oligometastatic prostate cancer (PC). (uludag.edu.tr)
  • Data from 1,160 breast, colorectal, and prostate cancer survivors participating in the American Cancer Society's National Cancer Survivor Transition Study were examined. (cdc.gov)
  • With four different treatment strategies in Sweden, a retrospective study based on the population-based Swedish Head and Neck Cancer Register (SweHNCR) was initiated. (lu.se)
  • Conclusion: In the present retrospective population-based study of BOTSCC brachytherapy was found to be of no beneficial value in curatively intended treatment. (lu.se)
  • This study represents the first in-depth analysis of prostate cancer among World Trade Center (WTC) rescue and recovery workers. (cdc.gov)
  • The study results will have practical implications on the surveillance and clinical management of prostate cancer, which is the most common cancer among male WTC Health Program members. (cdc.gov)
  • Data from nine waves of the Health and Retirement Study were used to examine employment status and weekly hours worked among cancer survivors (n = 483) and women without cancer (n = 6605). (cdc.gov)
  • We also analysed the all-cause survival in those receiving different SACT regimens (carboplatin plus pemetrexed, carboplatin plus gemcitabine, cisplatin plus gemcitabine, carboplatin plus paclitaxel, and other regimens) as their first-line treatments. (nzma.org.nz)
  • Outcome after surgical treatment of dermatofibrosarcoma protuberans: Is clinical follow‐up always indicated? (wiley.com)
  • Getting the right diagnosis and treatment for orchitis caused by bacteria can most often allow the testicle to recover normally. (medlineplus.gov)
  • Early detection is, however, hindered by lack of awareness of the disease, combined with limited access to early detection, diagnosis and treatment services. (who.int)
  • In addition the beneficial uses of NPs in drug delivery, cancer treatment, and gene therapy may cause unintentional human exposure. (cdc.gov)
  • TP53 MAF assessed on circulating DNA) and the marker CA-125 were correlated with overall disease burden before treatment and therapy response. (technologynetworks.com)
  • The gut microbiota has the potential to influence the efficacy of cancer therapy. (leibniz-hki.de)
  • According to Dr. Lin, they each brought unique expertise from their respective disciplines that helped bridge the worlds of cancer diagnostics and therapy. (ubc.ca)
  • Even when a cure is impossible, symptoms resulting from the cancer can often be relieved with treatment that improves the quality of life (palliative therapy). (msdmanuals.com)
  • Head and neck surgeon Brandon Prendes, MD joins our podcast to comment on recent research into advancing the treatment of head and neck cancer. (clevelandclinic.org)
  • The ethnicity of women undergoing fertility treatments like IVF can affect the rate of successful live births, according to new research by experts at The University of Nottingham and the Royal Derby Hospital's Fertility Unit . (nottingham.ac.uk)
  • Expert Review of Pharmacoeconomics & Outcomes Research is a bimonthly peer-reviewed medical journal covering all aspects of pharmacoeconomics. (wikipedia.org)
  • The editor-in-chief is A. Bottomley (European Organisation for Research and Treatment of Cancer). (wikipedia.org)
  • With roots in UBC research, Alpha-9 Theranostics is developing cancer radiotherapies that target tumours while avoiding healthy tissues. (ubc.ca)
  • Seeing these treatments move into clinical testing following more than a decade of basic and translational research is inspiring and the result of a tremendous collaborative effort. (ubc.ca)
  • Thanks to the cutting-edge research at UBC, these radiotherapies have tremendous potential to address a wide range of cancers," says Dr. Hirsch. (ubc.ca)
  • Worta McCaskill-Stevens, M.D., M.S., has spent much of her career advancing research that supports women with breast cancer, and the inclusion of underrepresented and underserved populations in clinical trials. (medlineplus.gov)
  • Fine-tuning these applications of cfDNA analysis is challenging and requires in-depth approaches, both at the genome sequencing level and computationally," explains Megan Barefoot, a MD/PhD student in the Wellstein lab at the Cancer Center and lead author of the article. (clpmag.com)
  • Because treatments are complex, specific approaches to care, called treatment protocols, have been developed to ensure that people receive the safest and most effective care. (msdmanuals.com)
  • Introduction There is a lack of consensus regarding the surgical management of advanced-stage endometrial cancer. (bmj.com)
  • Results Out of 1760 endometrial cancer cases screened 102 women with stage 3 and 4 disease were operable. (bmj.com)
  • 2 The closely watched Women's Health Initiative found no correlation to multivitamin use and breast cancer incidence in post-menopausal women. (naturalmedicinejournal.com)
  • 1 2 In East Africa, it is the leading cause of cancer deaths and has the highest age-standardised incidence rates of 42.7 per 100 000 women per year. (bmj.com)
  • An excess incidence of prostate cancer has been identified among World Trade Center (WTC) rescue and recovery workers included in the WTC Health Program (WTCHP) at Mount Sinai in New York. (cdc.gov)
  • The objectives of this project are to elucidate the reasons for the increased incidence of prostate cancer among WTCHP participants and to explore the behavior of these cancers. (cdc.gov)
  • There are fewer very large trials and more focus on subtypes of cancer that are more aligned with higher incidence rates among African American women, especially triple-negative breast cancer. (medlineplus.gov)
  • Conclusion/Implications Upfront surgery in advanced-stage endometrial carcinoma gives a respectable survival outcome after maximal surgical attempt. (bmj.com)
  • As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
  • That data will then be made available to with prostate cancer researchers around the world to create a centralized resource for researchers and clinicians and reduce wasteful costs on repeated genomic studies. (uclahealth.org)
  • By using cfDNA to compare damage to cells from various forms of treatment with undamaged normal cells from the same tissue, the researchers can analyze a treasure-trove of data about how the cells in a tissue are affected by treatments and other external forces. (clpmag.com)
  • The end-result of these analyses aids investigators in determining the tissue of origin of a cancer, for example, and also allows researchers, when comparing damaged cells to healthy cells, to see where the damage originated, especially if it was due to a certain type of treatment. (clpmag.com)
  • Alpha-9 Theranostics, a UBC spin-off company founded by three university researchers, has raised $75 million to develop next-generation radiopharmaceuticals that promise to meaningfully improve treatment for people with cancer. (ubc.ca)
  • The researchers filed a number of patents for the technologies they developed and worked with UBC's University-Industry Liaison Office and the Technology Development Office at BC Cancer to license the technology and eventually form Alpha-9. (ubc.ca)