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  • proteins
  • There are three main mechanisms to cause proteinuria: Due to disease in the glomerulus Because of increased quantity of proteins in serum (overflow proteinuria) Due to low reabsorption at proximal tubule (Fanconi syndrome) Proteinuria can also be caused by certain biological agents, such as bevacizumab (Avastin) used in cancer treatment. (wikipedia.org)
  • immune system
  • Unlike a preventative vaccine, such as for measles or mumps, BiovaxID is administered as a therapeutic cancer vaccine, designed to stimulate and "train" the patient's immune system to respond and attack cancerous cells, even long after therapy has been stopped - each vaccine being unique to that particular patient. (wikipedia.org)
  • tissues
  • While CXCR4's expression is low or absent in many healthy tissues, it was demonstrated to be expressed in over 23 types of cancer, including breast cancer, ovarian cancer, melanoma, and prostate cancer. (wikipedia.org)
  • Expression of this receptor in cancer cells has been linked to metastasis to tissues containing a high concentration of CXCL12, such as lungs, liver and bone marrow. (wikipedia.org)
  • CXCL12 (over-)expressing cancers might not sense the CXCL12 gradient released from the metastasis target tissues since the receptor, CXCR4, is saturated with the ligand produced in an autocrine manner. (wikipedia.org)
  • Foundation
  • This study was approved by the Mayo Foundation and the Dana-Farber Cancer Center Institutional Review Boards and conducted in accordance with the Declaration of Helsinki. (aacrjournals.org)
  • Research
  • A full list of the charity's current research projects can be found on the National Cancer Research Institute's International Cancer Research Portfolio. (wikipedia.org)
  • ovarian
  • Akt isoforms are overexpressed in a variety of human tumors, and, at the genomic level, are amplified in gastric adenocarcinomas (Akt1), ovarian (Akt2), pancreatic (Akt2) and breast (Akt2) cancer. (wikipedia.org)
  • patient
  • If you need immediate cancer-related information or patient program assistance, please call 800-227-2345 any time day or night. (cancer.org)
  • In a thorough workup for a patient with suspected cancer, the doctor may request some kidney function testing to determine whether the cancer is putting stress on the kidneys or other organ systems. (wisegeek.com)
  • cells
  • WM is a cancer that starts in B cells. (cancer.org)
  • The following signalling pathways have been implicated: CD154/CD40 Akt ubiquitination, p53 activation, cytochrome c release NF-κB WNT/beta-catenin mTOR ERK MAPK Bcl-2 The protein Src tyrosine kinase is overexpressed in Waldenström's macroglobulinemia cells compared with control B cells. (wikipedia.org)
  • Bone
  • To better understand the molecular changes that occur in Waldenstrom macroglobulinemia (WM), we employed antibody-based protein microarrays to compare patterns of protein expression between untreated WM and normal bone marrow controls. (aacrjournals.org)
  • Disorders
  • Bloodwise also writes and publishes patient information on a wide range of subjects including blood cancers and related disorders, treatment options and lifestyle issues, and booklets specifically designed for children with blood cancers. (wikipedia.org)
  • Liver
  • These cancers develop at the hilum, where the left and right hepatic ducts have joined and are just leaving the liver. (rahmacancercare.com)
  • Expression of this receptor in cancer cells has been linked to metastasis to tissues containing a high concentration of CXCL12, such as lungs, liver and bone marrow. (wikipedia.org)
  • tumor
  • The donated stem cells may replace the patient's immune system and help destroy any remaining cancer cells (graft-versus-tumor effect). (clinicaltrials.gov)
  • A malignant tumor is a group of cancer cells that can grow into (invade) surrounding tissues or spread (metastasize) to distant areas of the body. (rahmacancercare.com)
  • patient's immune system
  • Unlike a preventative vaccine, such as for measles or mumps, BiovaxID is administered as a therapeutic cancer vaccine, designed to stimulate and "train" the patient's immune system to respond and attack cancerous cells, even long after therapy has been stopped - each vaccine being unique to that particular patient. (wikipedia.org)
  • survival
  • Since it can block apoptosis, and thereby promote cell survival, Akt1 has been implicated as a major factor in many types of cancer. (wikipedia.org)
  • The survival rate for the most common form of childhood leukaemia has increased to over 90%, and for adults the survival rate is now as high as 70-80% for some forms of blood cancer. (wikipedia.org)
  • treatments
  • The Leukaemia Foundation invests millions of dollars per year in blood cancer research to improve treatments and find cures. (wikipedia.org)
  • They invest money into blood cancer research to ensure that all patients have their disease diagnosed early and accurately, receive personal, targeted treatments which are effective and have minimal side effects in order to beat or manage their cancer. (wikipedia.org)
  • Because of this geographical spread, it means 20 million people in the UK could have access to the very latest promising blood cancer treatments, if they needed it. (wikipedia.org)
  • patients
  • This phase II trial studies how well tacrolimus and mycophenolate mofetil works in preventing graft-versus-host disease in patients who have undergone total-body irradiation (TBI) with or without fludarabine phosphate followed by donor peripheral blood stem cell transplant for hematologic cancer. (clinicaltrials.gov)
  • protein
  • The following signalling pathways have been implicated: CD154/CD40 Akt ubiquitination, p53 activation, cytochrome c release NF-κB WNT/beta-catenin mTOR ERK MAPK Bcl-2 The protein Src tyrosine kinase is overexpressed in Waldenström's macroglobulinemia cells compared with control B cells. (wikipedia.org)
  • Provides
  • Provides information about the disease, treatment options, and the differences between Adult and Childhood cancer. (dmoztools.net)
  • cells
  • Giving low doses of chemotherapy, such as fludarabine phosphate, and TBI before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. (clinicaltrials.gov)
  • Drugs used in chemotherapy, such as 3-AP and gemcitabine (GEM), work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. (clinicaltrials.gov)
  • 3-AP may help gemcitabine kill more cancer cells by making the cells more sensitive to the drug. (clinicaltrials.gov)
  • disease
  • There are three main mechanisms to cause proteinuria: Due to disease in the glomerulus Because of increased quantity of proteins in serum (overflow proteinuria) Due to low reabsorption at proximal tubule (Fanconi syndrome) Proteinuria can also be caused by certain biological agents, such as bevacizumab (Avastin) used in cancer treatment. (wikipedia.org)
  • tissues
  • CXCL12 (over-)expressing cancers might not sense the CXCL12 gradient released from the metastasis target tissues since the receptor, CXCR4, is saturated with the ligand produced in an autocrine manner. (wikipedia.org)