• tumor
  • KLH-IA) were determined in the MB-49 intravesical murine bladder tumor model. (curehunter.com)
  • The iCaRe2 is a multi-center, semantically-interoperable and easily-customizable cancer data resource which is aimed at collecting, managing, mining and sharing the comprehensive, multi-dimensional cancer-related data on cancer patients and biospecimens (such as tumor specimens, germ line DNA, serum, urine, and plasma) collected from those individuals. (clinicaltrials.gov)
  • At present, this framework has been incrementally expanded to include the Thoracic Oncology Collaborative Registry (TOCR), GenitoUrinary Cancer Collaborative Registry (GUCaRe), Head and Neck Cancer Collaborative Registry (HNCCR), Gastrointestinal & Abdominal Cavity Cancer Collaborative Registry (GACCaRe), Central Nervous System Tumor Collaborative Registry (CTCR), Leukemia and Myeloid Neoplasm Registry (LeMN) , Gynecological Cancer Collaborative Registry (GCCR), Sarcoma Collaborative Registry (SARCR), Melanoma Collaborative Registry (MELCR) and Auxiliary Cancer Registry (ACR). (clinicaltrials.gov)
  • Also searched for Neoplasm , Tumor , and Neoplastic syndrome . (clinicaltrials.gov)
  • The progression free/ recurrence free/ bladder-intact survival is defined as the time from start of study treatment to first documentation of objective tumor progression, recurrence, bladder resection or irradiation or to death due to any cause, whichever comes first. (clinicaltrials.gov)
  • Often the tumor will regrow from those resistant cells, the patient will relapse, and the therapy that had been previously used will no longer kill the cancer cells. (wikipedia.org)
  • A urogenital neoplasm is a tumor of the urogenital system. (wikipedia.org)
  • p16 plays an important role in cell cycle regulation by decelerating cells progression from G1 phase to S phase, and therefore acts as a tumor suppressor that is implicated in the prevention of cancers, notably melanoma, oropharyngeal squamous cell carcinoma, cervical cancer, and esophageal cancer. (wikipedia.org)
  • Hypermethylation of tumor suppressor genes has been implicated in various cancers. (wikipedia.org)
  • 2007), "Chapter 30: Cancers of Rare Sites", SEER Survival Monograph: Cancer Survival Among Adults: US SEER Program, 1988-2001, Patient and Tumor Characteristics, SEER Program, NIH Pub. (wikipedia.org)
  • diagnosis
  • iii) the TCCR (Thyroid Cancer Collaborative Registry - established in 2006), and (iv) the GPHID (Great Plains Health Informatics Database - established in 2011 to enroll subjects who have no personal history of cancer diagnosis at the time of enrollment). (clinicaltrials.gov)
  • These questions will ask about foods eaten either one year ago or one year before the first diagnosis of cancer. (clinicaltrials.gov)
  • All these symptoms are non-specific and can also arise with a range of problems other than cancer, and a diagnosis can only be made following confirmatory investigations such as computed tomography (CT) scans, laparotomy and/or a biopsy of the ovary. (wikipedia.org)
  • The diagnosis of urachal cancer can be difficult and usually requires a multidisciplinary approach. (wikipedia.org)
  • Signs that allow early diagnosis include changes in bowel and bladder function and loss of feeling in groin. (wikipedia.org)
  • 2001
  • Between 1988 and 2001 in the United States, cancer surveillance reports to SEER included 1,333 cases of ureteral cancer in adults: 808 male and 525 female, 1,158 white and 42 black. (wikipedia.org)
  • commonly
  • There are good reasons to suspect that the quantity and quality of food influence both the overall risk of development of many forms of cancer and the types of cancer which occur most commonly. (biomedsearch.com)
  • Cancer of the bladder is the 4th most commonly diagnosed cancer and 7th leading cause of cancer death in the American men, and represents an important target for mortality-reducing efforts. (clinicaltrials.gov)
  • they may occur everywhere in the colon and they are the least likely colon polyps to develop into colon cancer Tubulovillous Villous adenomas are commonly found in the rectal area and they are normally larger in size than the other two types of adenomas. (wikipedia.org)
  • Ultrasound is commonly performed to investigate problems of the kidney and/or urinary tract. (wikipedia.org)
  • lung
  • Carriers of germline mutations in CDKN2A have besides their high risks of melanoma also increased risks of pancreatic, lung, laryngeal and oropharyngeal cancers and tobacco smoking exacerbates carriers' susceptibility for such non-melanoma cancers. (wikipedia.org)
  • Diseases
  • The data registry and biospecimen bank will provide core support services for future IRB approved multidisciplinary research on cancer and other chronic diseases carried out by members of the Fred and Pamela Buffett Cancer Center as well as internal and external research collaborators from different participating institutions/centers. (clinicaltrials.gov)
  • Somatic evolution is important in the process of aging as well as the development of some diseases, including cancer. (wikipedia.org)
  • The causes of diseases of the body are common to the urinary tract. (wikipedia.org)
  • Urachal cancer was mentioned by Hue and Jacquin in 1863 followed by an elaborate work by T. Cullen in 1916 about diseases of the umbilicus, while C. Begg further characterized urachal cancer in the 1930s. (wikipedia.org)
  • pathology
  • The iCaRe2 serves as a collaboration platform for studies (including clinical trials) performed in centers with expertise in cancer biology, pathology, epidemiology, genetics, early detection, and patient care. (clinicaltrials.gov)
  • CAT scans and MRI can also be useful in localising urinary tract pathology. (wikipedia.org)
  • It was there that he began his recognized studies on the pathology of colon cancer. (wikipedia.org)
  • clonal
  • Clonal expansion is the signature of natural selection in cancer. (wikipedia.org)
  • In the decades that followed, cancer was recognized as having a clonal origin associated with chromosomal aberrations. (wikipedia.org)
  • urine
  • For example: Urinary tract infections (UTIs), interstitial cystitis incontinence (involuntary loss of urine), benign prostatic hyperplasia (where the prostate overgrows), prostatitis (inflammation of the prostate). (wikipedia.org)
  • Because the bladder is in contact with urine for extended periods, chemicals that become concentrated in the urine can cause Bladder cancer. (wikipedia.org)
  • For example, cigarette smoking leads to the concentration of carcinogens in the urine and is a leading cause of bladder cancer. (wikipedia.org)
  • tumour
  • Finally, the importance of avoiding mineral imbalance when conducting animal studies designed to evaluate the safety of food constituents and additives is stressed in relation to urinary-calculus formation and bladder-tumour risk. (biomedsearch.com)
  • infection
  • Urinary retention, which is a common complication of benign prostatic hyperplasia (BPH), though it can also be caused by other types of urinary tract obstruction, nerve dysfunction, tethered spinal cord syndrome, constipation, infection and certain medications. (wikipedia.org)
  • Symptoms
  • Urachal cancer can exist for some years without any symptoms. (wikipedia.org)
  • Play media Signs and symptoms of TCC are entirely dependent on the location and extent of the cancer. (wikipedia.org)
  • Symptoms include, low back pain, pain that radiates down the leg, numbness around the anus, and loss of bowel or bladder control. (wikipedia.org)
  • Vaginal
  • For botryoid rhabdomyosarcoma of the vagina, the most common clinical finding is vaginal bleeding but vaginal bleeding is not specific for sarcoma botryoides: other vaginal cancers are possible. (wikipedia.org)
  • retention
  • Detrusor weaknesses causing urinary retention and post-void residual incontinence as assessed by bladder scanning the patient after the patient has urinated. (wikipedia.org)
  • Colon Cancer
  • This evolutionary process has first been shown by the studies of Bert Vogelstein in colon cancer. (wikipedia.org)
  • Colon polyps are a concern because of the potential for colon cancer being present microscopically and the risk of benign colon polyps transforming over time into malignant ones. (wikipedia.org)
  • Since most polyps are asymptomatic, they are usually discovered at the time of colon cancer screening. (wikipedia.org)
  • Even though colon cancer is usually not found in polyps smaller than 2.5 cm, all polyps found are removed since the removal of polyps reduces the future likelihood of developing colon cancer. (wikipedia.org)
  • The adenomatous polyp is considered pre-malignant, i.e., likely to develop into colon cancer. (wikipedia.org)
  • Multiple adenomatous polyps often result from familial polyposis coli or familial adenomatous polyposis, a condition that carries a very high risk of colon cancer. (wikipedia.org)
  • Although polyps do not carry significant risk of colon cancer, tubular adenomatous polyps may become cancerous when they grow larger. (wikipedia.org)
  • Risk
  • The striking effects of dietary restriction on cancer risk in laboratory rats and mice and the possibility that dietary restraint may be beneficial in man are discussed. (biomedsearch.com)
  • The investigators will look at risk factors to learn more about how these impact cancer. (clinicaltrials.gov)
  • If the cases have previously completed athe 'the 'Urothelial Baseline Questionnaire,' in an MSKCC urology clinic they will not need to complete the urothelial cancer risk questionnaire. (clinicaltrials.gov)
  • Urothelial Cancer Registry- These participants will be requested to complete the risk factor questionnaire and to provide a saliva sample for DNA extraction. (clinicaltrials.gov)
  • Mutations resulting in deletion or reduction of function of the CDKN2A gene are associated with increased risk of a wide range of cancers and alterations of the gene are frequently seen in cancer cell lines. (wikipedia.org)
  • Familial adenomatous polyposis Peutz-Jeghers syndrome Turcot syndrome Juvenile polyposis syndrome Cowden disease Bannayan-Riley-Ruvalcaba syndrome (Bannayan-Zonana syndrome) Gardner's syndrome Cronkhite-Canada syndrome Malignant Hamartomatous Hyperplastic Inflammatory: Inflammatory fibroid polyp Adenomatous polyps, or adenomas, are polyps that grow on the lining of the colon and which carry a high risk of cancer. (wikipedia.org)
  • Tobacco smoking is associated with an increased risk of ureteral cancer. (wikipedia.org)
  • Occupational exposure to certain chemicals is also a risk factor for bladder cancer. (wikipedia.org)
  • Cervical
  • The Study Focusses on the Evaluation of New Tissue Biomarkers for Cervical Cancer and Its Preinvasive Lesions. (netdata.com)
  • progression
  • On one end, the hypermethylation, mutation, or deletion of p16 leads to downregulation of the gene and can lead to cancer through the dysregulation of cell cycle progression. (wikipedia.org)
  • Patient
  • Patient planned to receive hypofractionated radiotherapy to the bladder. (clinicaltrials.gov)
  • Side effects include a small chance of developing systemic tuberculosis or the patient becoming sensitized to the BCG causing severe intolerance and a possible reduction in bladder volume due to scarring. (wikipedia.org)
  • variation
  • There are three necessary and sufficient conditions for natural selection, all of which are met in a neoplasm: There must be variation in the population. (wikipedia.org)
  • Sarcoma
  • Sarcoma botryoides or botryoid sarcoma or botryoid rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma, that can be observed in the walls of hollow, mucosa lined structures such as the nasopharynx, common bile duct, urinary bladder of infants and young children or the vagina in females, typically younger than age 8. (wikipedia.org)
  • somatic
  • Early mathematical modeling of cancer, by Armitage and Doll, set the stage for the future development of the somatic evolutionary theory of cancer. (wikipedia.org)
  • Armitage and Doll explained the cancer incidence data, as a function of age, as a process of the sequential accumulation of somatic mutations (or other rate limiting steps). (wikipedia.org)
  • Advances
  • Advances in cytogenetics facilitated discovery of chromosome abnormalities in neoplasms, including the Philadelphia chromosome in chronic myelogenous leukemia and translocations in acute myeloblastic leukemia. (wikipedia.org)