AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth CareGeographicals
Neoplasm StagingPancreatic NeoplasmsNeoplasmsLung NeoplasmsEarly Detection of CancerPrognosisOvarian NeoplasmsStomach NeoplasmsNeoplasm InvasivenessBreast NeoplasmsNeoplasm MetastasisProstatic NeoplasmsColonic NeoplasmsSkin NeoplasmsRetrospective StudiesEndosonographyTomography, X-Ray ComputedLiver NeoplasmsNeoplasm ProteinsSurvival AnalysisColorectal NeoplasmsNeoplasms, Multiple PrimaryPositron-Emission TomographySensitivity and SpecificityTumor Markers, BiologicalCarcinomaNeoplasms, Cystic, Mucinous, and SerousRectal NeoplasmsNeoplasm Recurrence, LocalAdenocarcinomaLymphatic MetastasisKidney NeoplasmsDNA, NeoplasmNeoplasms, Second PrimaryLymph NodesCarcinoma, Squamous CellThyroid NeoplasmsFollow-Up StudiesRadiopharmaceuticalsUrinary Bladder NeoplasmsGene Expression Regulation, NeoplasticProspective StudiesEsophageal NeoplasmsGastrointestinal NeoplasmsFluorodeoxyglucose F18Carcinoma, Non-Small-Cell LungDisease ProgressionUterine Cervical NeoplasmsBone NeoplasmsAdenocarcinoma, MucinousPredictive Value of TestsMice, NudeImmunohistochemistryCombined Modality TherapyMouth NeoplasmsNeoplasms, Glandular and EpithelialAntigens, NeoplasmEndometrial NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsAntineoplastic AgentsDisease-Free SurvivalCancer VaccinesNeoplasms, Radiation-InducedLymph Node ExcisionSurvival RateReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionMediastinumHead and Neck NeoplasmsTreatment OutcomeLymphomaCarcinoma, Pancreatic DuctalBiopsyMutationBiopsy, NeedleNeoplasm TransplantationGenetic Predisposition to DiseaseRegistriesRisk AssessmentRiskCell Line, TumorMediastinoscopyKaplan-Meier EstimateGene Expression ProfilingUnited StatesAge FactorsNeoplasms, ExperimentalDrug Resistance, NeoplasmCarcinoma, PapillaryRNA, MessengerNeoplasm GradingChemotherapy, AdjuvantAdenomaMelanomaBile Duct NeoplasmsSentinel Lymph Node BiopsyTesticular NeoplasmsMultivariate AnalysisCell Transformation, NeoplasticRisk Factors
MetastasisPrognosisTumorsTumorOncologyDiagnosisCarcinomaPathologyClinicalGradingGenesChemotherapyEpidemiologyNeuroendocrine neoplasmsPathologicalEpithelialMalignant neoplasmsEsophageal cancerBenignDiseaseColorectal cancerRisk FactorsMastectomyBreast cancerLUNGSymptoms2021PrimarySurgeryAntigensSurvival RatePancreatic cancersLiverMortalityMethodsSerumIncidenceMetastaticMetastasesProstateAbnormalFactorsHistologicallyCervical
Metastasis7
  • Scholars@Duke publication: Metastasis dynamics for non-small-cell lung cancer: effect of patient and tumor-related factors. (duke.edu)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
  • The histologic subtype, metastasis site, and certain patient characteristics can offer clues to the cancer primary. (medscape.com)
  • METHOD OF STUDY: A cross-sectional study was performed to examine the correlation between CD200 protein expression in the primary tumors from postoperative Stage I-IIIA human breast cancer and the likelihood of regional lymph node metastasis. (mcmaster.ca)
  • CONCLUSION: CD200 expression by early-stage human breast cancer cells in primary tumors did not correlate with increased regional lymph node metastasis. (mcmaster.ca)
  • Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
  • According to the Barcelona Clinic Liver Cancer (BCLC) staging standard, HCC is divided into four stages, of which stage B is equivalent to the intermediate stage of Tumor Node Metastasis (TNM) staging. (hindawi.com)
Prognosis7
  • Prognosis --Several studies have demonstrated that a large proportion of neuroendocrine differentiated prostatic neoplasms are positive for neuron-specific enolase and chromogranin A [4,6]. (cancernetwork.com)
  • The expression of the identified long noncoding RNAs was downregulated in cancer tissue samples compared with normal tissue samples, and these long noncoding RNAs correlated with a favorable prognosis in breast cancer patients and the patients in the pancancer cohort. (cancerindex.org)
  • The aim of this research was to develop and validate an mRNA-based signature for predicting the prognosis of patients with bladder cancer. (biomedcentral.com)
  • utilized the expression of B4GALT1 to predict the prognosis of patients with muscle-invasive bladder cancer, and the expression of B4GALT1 was correlated with OS of patients with BC [ 8 ]. (biomedcentral.com)
  • The treatment of patients in this stage is more complex than that in the early stage, and their prognosis is better than that in the advanced stage, so special attention should be paid to it. (hindawi.com)
  • Prognosis and outcome of renal cell carcinoma are influenced by tumor stage and grade at the time of diagnosis. (diagnosticimaging.com)
  • The prognosis for this type of cancer is very unfavorable. (medicalwholesome.com)
Tumors12
  • 2011. NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). . (oregonstate.edu)
  • Tumors or cancer of the PANCREAS. (lookformedical.com)
  • Tumors or cancer of the SKIN. (lookformedical.com)
  • Tumors or cancer of the LUNG. (lookformedical.com)
  • Tumors or cancer of the LIVER. (lookformedical.com)
  • Tumors or cancers of the KIDNEY. (lookformedical.com)
  • Tumors or cancer of the THYROID GLAND. (lookformedical.com)
  • No staging system exists for cancers of unknown primary origin-more precisely, histologically proven metastatic malignant tumors for which the primary site cannot be identified during pretreatment evaluation. (medscape.com)
  • The State of Rio Grande do Norte has a high incidence of penile cancer with a high frequency of locally advanced tumors at diagnosis and in younger patients younger than 50. (clinmedjournals.org)
  • We aim to evaluate this staging system compared to the 7th edition AJCC staging system and European Neuroendocrine Tumors Society (ENETS) system. (gnu.ac.kr)
  • MSCT can detect, characterize, and stage renal tumors in one fast, high-resolution examination, assuming that a tailored multiphasic protocol is followed. (diagnosticimaging.com)
  • Breast Cancer Breast cancers are most often epithelial tumors involving the ducts or lobules. (msdmanuals.com)
Tumor28
  • Automated administrative databases, medical records, and tumor registries were used to identify women aged 65 years or older who received BCS or mastectomy to treat stage I or II breast cancer diagnosed from January 1, 1990, through December 31, 1994. (healthpartners.com)
  • Although the tumor was considered to have been fully resected and had not spread to any nodes, the patient died of recurrent cancer within 1 year. (medscape.com)
  • BACKGROUND: We studied event dynamics (probability of an event occurring over a specific time interval) in patients undergoing surgery for early-stage non-small-cell lung cancer (NSCLC) according to patient and tumor characteristics. (duke.edu)
  • The goals of surgical intervention include both staging and tumor debulking. (medscape.com)
  • Interestingly the mechanisms behind the molecules at work in the study at hand rely on basic cancer biology principles, namely that of tumor acidity and disease microenvironment. (urotoday.com)
  • In the present study our group showed the utility of intravesical instillation of the ICG pHLIP ® (ICG is a FDA approved near infrared fluorescent dye and pHLIP ® is a pH (Low) Insertion Peptide, which targets tumor acidity) construct for bladder tumor identification and staging. (urotoday.com)
  • While the current study was performed on ex-vivo specimens, preliminary data on toxicity of the molecule are encouraging and a natural next step will be immediate preoperative intravesical instillation for patients undergoing transurethral bladder tumor resections to aid in tumor identification and perhaps even allow for real time tumor staging. (urotoday.com)
  • Current foci for investigation at our institution include IRB approved projects applying the ICG pHLIP ® construct to upper tract urothelial and renal cell neoplasms for tumor identification and staging purposes. (urotoday.com)
  • The cancer cell multiplies, and a cancerous or malignant tumor develops. (medicinenet.com)
  • Purpose The 8th edition of the American Joint Committee on Cancer (AJCC) staging system for pancreatic neuroendocrine tumor (PNET) included several significant changes. (gnu.ac.kr)
  • RESULTS: Fifty-eight percentage of patients had strong CD200(+) tumor staining (71% of Stage I and 53% Stage II-IIIA). (mcmaster.ca)
  • Positive values for the tumor markers appeared from second stage (Hermreck classification). (unisr.it)
  • Results: Within clinical tumor stage, three groups (T1a- 2a, T2b-c, and T3a-b) were observed to have a distinctly different rate of SVI. (elsevierpure.com)
  • Probability plots were constructed to display the likelihood of SVI as a function of pretherapy clinical tumor stage, Gleason primary grade, and serum prostate-specific antigen value. (elsevierpure.com)
  • Conclusion: In the patient with a new diagnosis of localized CaP, clinical tumor stage as determined by digital rectal examination, diagnostic biopsy tumor (Gleason primary) grade, and pretherapy serum prostate-specific antigen value were significant factors for development of a model that estimated the likelihood of SVI. (elsevierpure.com)
  • Landscape of tumor suppressor long noncoding RNAs in breast cancer. (cancerindex.org)
  • The landscape and biological functions of tumor suppressor long noncoding RNAs in breast cancer are still unknown. (cancerindex.org)
  • Data from whole transcriptome sequencing of 33 breast specimens in the Harbin Medical University Cancer Center cohort and The Cancer Genome Atlas was applied to identify and validate the landscape of tumor suppressor long noncoding RNAs, which was further validated by The Cancer Genome Atlas pancancer data including 33 cancer types and 12,839 patients. (cancerindex.org)
  • Next, the expression model, prognostic roles, potential biological functions and epigenetic regulation of tumor suppressor long noncoding RNAs were investigated and validated in the breast cancer and pancancer cohorts. (cancerindex.org)
  • Finally, EPB41L4A-AS2 was selected to validate our novel finding, and the tumor suppressive roles of EPB41L4A-AS2 in breast cancer were examined. (cancerindex.org)
  • Computed tomography (CT) and endoscopy/endoscopic ultrasonography are usually performed to initially stage patients with esophageal cancer, to determine primary tumor response, and to detect nodal and distant metastases after preoperative therapy. (houstonmethodist.org)
  • TACE combined with lenvatinib and sintilimab in the treatment of Barcelona Clinic Liver Cancer (BCLC) stage B hepatocellular carcinoma can effectively control the tumor progression and prolong the survival time of patients. (hindawi.com)
  • Renal cell cancer is the most frequently encountered malignant tumor in the kidney. (diagnosticimaging.com)
  • The nephrographic phase is most effective in tumor localization and staging. (diagnosticimaging.com)
  • 8 The earlier a malignant mass is detected on imaging, the greater the chance of it being an early-stage tumor of low grade. (diagnosticimaging.com)
  • Osteosarcoma is a malignant bone neoplasm with aggressive clinical evolution which is usually diagnosed in late stages of the disease, when primary tumor reaches significant dimensions. (bvsalud.org)
  • Your health care provider might see a tumor, such as skin or oral cancer. (medlineplus.gov)
  • If the tumor is cancerous, the outcome depends on the type and stage of the tumor at diagnosis. (medlineplus.gov)
Oncology6
  • We did a randomised, open-label phase 3 KRISTINE trial in 68 Translational Research In Oncology centres (hospitals and specialty cancer centres in Asia, Europe, USA, and Canada). (nih.gov)
  • ConclusionMore than half of the Nordic Gynecological Oncology Centers already report a clinical FIGO stage influenced by pretreatment imaging findings. (diva-portal.org)
  • Several risk factors can lead to the development of FN in cancer patients, the most representative were listed in the clinical practice guideline developed by the American Society of Clinical Oncology along with the Infectious Diseases Society of America (ASCO/IDSA). (ijpsonline.com)
  • Cancers is a peer-reviewed , open access journal of oncology, published semimonthly online by MDPI. (mdpi.com)
  • The Irish Association for Cancer Research (IACR) , Spanish Association for Cancer Research (ASEICA) , Biomedical Research Centre (CIBM) , British Neuro-Oncology Society (BNOS) and Spanish Group for Cancer Immuno-Biotherapy (GÉTICA) are affiliated with Cancers and their members receive a discount on the article processing charges. (mdpi.com)
  • Erasmus, JJ & Munden, RF 2007, ' The Role of Integrated Computed Tomography Positron-Emission Tomography in Esophageal Cancer: Staging and Assessment of Therapeutic Response ', Seminars in Radiation Oncology , vol. 17, no. 1, pp. 29-37. (houstonmethodist.org)
Diagnosis13
  • We did the randomisation via an interactive response system under a permuted block randomisation scheme (block size of four), stratified by hormone receptor status, stage at diagnosis, and geographical location. (nih.gov)
  • An x-ray is often the first diagnostic test that osteosarcoma patients receive, and an experienced radiologist may recognize immediately that bone cancer is the likely diagnosis. (sarcomahelp.org)
  • Most patients received the diagnosis in the initial phase of the disease, but 20.2% were diagnosed in stage IV. (clinmedjournals.org)
  • Jaiswal K, Hull M, Furniss AL, Doyle R, Gayou N, Bayliss E. Delays in Diagnosis and Treatment of Breast Cancer: A Safety-Net Population Profile. (ucdenver.edu)
  • The following sections review the use of integrated CT-PET imaging in determining the T, N, and M descriptors of the American Joint Commission on Cancer's 2002 guidelines for pathologic and clinical staging at initial diagnosis and after chemoradiation therapy in those patients being considered for surgical resection. (houstonmethodist.org)
  • Multiphasic CT acquisitions should be performed after injection of a single contrast bolus to achieve the highest staging accuracy and permit differential diagnosis. (diagnosticimaging.com)
  • In the first stage of diagnosis, X-ray of the esophagus with contrast is performed, which most often shows oesophageal ulcers and strictures . (medicalwholesome.com)
  • A diagnosis of cancer may be suspected based on history and physical examination but requires confirmation by biopsy and histopathologic examination. (msdmanuals.com)
  • Introduction to the SEER Program The National Cancer Act of 1971 mandated the collection, analysis, and dissemination of all data useful in the prevention, diagnosis, and treatment of cancer. (cdc.gov)
  • If a case was diagnosed in 2018 through 2020, stage at diagnosis is recorded using the Summary Stage 2018 variable value. (cdc.gov)
  • All of them were interviewed and evaluated by the Hospital Anxiety and Depression Scale at different stages: Post-diagnosis (n= 9), post-surgical (n= 8) and chemotherapy (n= 10). (bvsalud.org)
  • In it is a misconception to believe that itive diagnosis is based on histology many lower-income countries, death cancer registry data can be auto- (although the proportion of cases for registration is confined to deaths in matical y derived from the health which the tumour is examined by the hospital (with no medical certification information system. (who.int)
  • A cancer diagnosis often causes a lot of anxiety and can affect a person's entire life. (medlineplus.gov)
Carcinoma5
  • The main part of the pathological development turns to be cancer or carcinoma. (imedix.com)
  • However, investigators have demonstrated precursor cancerous lesions in the fallopian tube (tubal in-situ carcinoma [TIC]) and have provided evolutionary evidence that many advanced serous ovarian cancers originate in the fallopian tubes. (medscape.com)
  • Small bowel metastases from primary carcinoma of the lung are very uncommon and occur usually in patients with terminal stage disease. (ispub.com)
  • One third of patients with cancer of unknown primary origin have poorly or undifferentiated carcinoma. (medscape.com)
  • Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed and fourth most lethal neoplasm worldwide. (hindawi.com)
Pathology3
  • Comparison of AJCC stage determined by post-treatment yMRI with final pathology showed understaging in 13% (55/429) and overstaging in 34% (148/429). (lu.se)
  • Agreement between yMRI and final pathology for T-stage, N-stage, or AJCC status were each graded as 'fair' only (n = 429, Kappa 0.25, 0.26 and 0.35 respectively). (lu.se)
  • Pathology laboratories these limited data should be exploited methods used, skilled cancer reg- always keep a record of their work by the registry. (who.int)
Clinical14
  • AJCC TNM stage and WHO grade (G) are two widely used staging systems to guide clinical management for pancreatic neuroendocrine neoplasms (panNENs), based on clinical staging and pathological grading information, respectively. (bvsalud.org)
  • The present survey reports the influence of pretreatment imaging findings on the recorded clinical International Federation of Gynecology and Obstetrics (FIGO) stage in Nordic countries and its impact on treatment planning and preferred surgical approach in cervical cancer. (diva-portal.org)
  • In 58% (11/19) of the centers, imaging findings were reported to influence the clinical staging. (diva-portal.org)
  • This review will examine the evidence for the neuroendocrine progression of prostate cancer and the clinical utility of chemothera- peutic agents that are being investigated for the management of late stage disease. (cancernetwork.com)
  • Combined with observations of neuroendocrine enrichment in cases of poor clinical response to androgen deprivation therapy, these findings support the notion that the clonal expansion of AR-negative neuroendocrine cells may play a critical role in the development of androgen-insensitive metastatic prostate cancer. (cancernetwork.com)
  • The clinical relevance of immunohistological detection of neuroendocrine tissue in prostate cancer patients has been the focus of many investigators. (cancernetwork.com)
  • Malignant neoplasms develop in two stages: preclinical and clinical. (imedix.com)
  • TDM in colorectal cancer can reduce toxicity, improve efficacy and clinical outcome, and can be routinely used in 5-FU-based chemotherapy. (medscimonit.com)
  • To trace the clinical and epidemiological profile of penile cancer in Rio Grande do Norte/Brazil and relate them to data published in the literature. (clinmedjournals.org)
  • Patients diagnosed with pancreatic cancer are encouraged to seek out clinical trials that will ultimately improve pancreatic cancer treatment. (medicinenet.com)
  • Methods and Materials: Between January 1988 and December 1993, 2959 patients underwent radical retropubic prostatectomy, with or without pelvic lymph node dissection, as initial therapy for clinical Stage T1a-3bN0-XM0 CaP. (elsevierpure.com)
  • Decision curve analysis (DCA) indicated that the clinical value of the nomogram was higher than the stage model and TNM model in predicting overall survival analysis. (biomedcentral.com)
  • The most common histology-high-grade serous epithelial ovarian cancer-is considered as a single clinical entity along. (msdmanuals.com)
  • If there involve visits to individual clinical in feature of the CanReg5 software are special cancer treatment facili- services. (who.int)
Grading1
  • Should this be confirmed, this may add to the routine histological grading in patients with progressive prostate cancer [6]. (cancernetwork.com)
Genes1
  • Functional enrichment analysis of candidate genes suggested several pathways and mechanisms related to cancer. (biomedcentral.com)
Chemotherapy17
  • The question of whether platinum-based adjuvant chemotherapy can improve outcomes in patients with early-stage epithelial ovarian cancer is an important one. (nih.gov)
  • We carried out a multicenter, open randomized trial to determine whether adjuvant chemotherapy would improve overall survival and prolong recurrence-free survival in women with early-stage epithelial ovarian cancer. (nih.gov)
  • These results suggest that platinum-based adjuvant chemotherapy improves survival and delays recurrence in patients with early-stage ovarian cancer. (nih.gov)
  • We did a phase 3 trial to assess a neoadjuvant regimen for HER2-positive breast cancer that replaces traditional systemic chemotherapy with targeted treatment. (nih.gov)
  • In the subset of 886 chemotherapy-naive women treated with tamoxifen, those treated with tamoxifen for less than 1 year had a substantially higher breast cancer mortality rate than those exposed 5 years or more (adjusted HR=6.26, 95% CI, 3.10 to 12.64). (healthpartners.com)
  • Thus, neuroendocrine-specific growth factors such as bombesin represent novel therapeutic targets and may also be important in the selection of patients for aggressive chemotherapy, which has been rather ineffective in prostate cancer. (cancernetwork.com)
  • [ 1 , 2 ] Currently, both early-stage and advanced-stage fallopian tube cancers are treated in much the same way as ovarian cancers-that is, with surgery followed by chemotherapy. (medscape.com)
  • In fact, most patients with stage I disease are treated with adjuvant chemotherapy because of the luminal structure of the organ and the risk of shedding cells out of the tubes and into the abdominal cavity. (medscape.com)
  • Accordingly, the chemotherapy used to treat primary fallopian tube cancers is based on the standard management of ovarian cancers. (medscape.com)
  • Consensus-based guidelines from the National Comprehensive Cancer Network (NCCN) suggest administering three to six cycles of chemotherapy for stage IA-IC disease and six to eight cycles for stage II-IV disease. (medscape.com)
  • As in ovarian cancer, the use of intraperitoneal (IP) chemotherapy must be considered the current standard treatment option in patients with stage II-IV disease. (medscape.com)
  • The impact of therapeutic drug management (TDM) on reducing toxicity and improving efficacy in colorectal cancer (CRC) patients receiving fluorouracil-based chemotherapy is still unclear. (medscimonit.com)
  • Febrile neutropenia is a common and serious complication of cancer chemotherapy. (ijpsonline.com)
  • Febrile Neutropenia (FN) is a common complication of chemotherapy and a main cause of morbidity and mortality in cancer patients[ 1 ]. (ijpsonline.com)
  • Chemotherapy after surgery can lower the chances of the cancer returning. (medicinenet.com)
  • Chemotherapy for metastatic pancreatic cancer can extend the life and improve the quality of life, but it rarely cures the patient. (medicinenet.com)
  • Esophageal cancer is treated with surgery or chemotherapy. (medicalwholesome.com)
Epidemiology1
  • The act resulted in the establishment of the National Cancer Program under which the Surveillance, Epidemiology, and End Results (SEER) Program was developed. (cdc.gov)
Neuroendocrine neoplasms1
  • The heterogeneous nature of Neuroendocrine Neoplasms must be understood to avoid confusion and chaos in patient groups. (ronnyallan.net)
Pathological4
  • The primary objective was to compare the number of patients who achieved a pathological complete response (ypT0/is, ypN0), between groups in the intention-to-treat population (two-sided assessment), based on local evaluation of tumour samples taken at breast cancer surgery done between 14 days and 6 weeks after completion of neoadjuvant therapy. (nih.gov)
  • MATERIAL/METHODS: The pathological staging was determined according to the TNM and Dukes' classification. (medscimonit.com)
  • The secondary endpoint was agreement between post-treatment MRI restaging (yMRI) and final pathological staging. (lu.se)
  • A nomogram was constructed based on the risk score, pathological stage, and age. (biomedcentral.com)
Epithelial2
  • Only a small percentage of women with epithelial fallopian tube cancers are treated with surgery alone. (medscape.com)
  • Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer. (mdpi.com)
Malignant neoplasms1
  • The death of ESPN sportscaster Stuart Scott has generated interest in cancer deaths in the U.S. Cancer is the second leading cause of death in the U.S. The number of cancer deaths are available from the multiple cause of death option on the CDC WONDER database using the C00-C97 ICD Code, "Malignant Neoplasms. (cdc.gov)
Esophageal cancer8
  • BACKGROUND: Several disadvantages of the TNM classification have resulted in a search for a simpler, clearer, and more reliable staging system for esophageal cancer. (medscimonit.com)
  • CONCLUSIONS: Dukes' staging system for esophageal cancer is simpler, clearer and more accurate, and could thus be a better prognostic tool than the TNM classification. (medscimonit.com)
  • Positron-emission tomography (PET) with [18F]-fluoro-2-deoxy-D-glucose and integrated CT-PET are useful in the initial staging of patients with esophageal cancer as well as in the prediction of pathologic response, disease-free interval, and overall survival after preoperative therapy. (houstonmethodist.org)
  • Esophageal cancer is caused by factors that favor food retention in the esophagus (e.g. esophageal stricture, atony and spasms) and thus mechanical, chemical or thermal irritation of its mucosa. (medicalwholesome.com)
  • Every year 1,300 people in Poland find out that they have esophageal cancer. (medicalwholesome.com)
  • Early esophageal cancer is asymptomatic and therefore is detected sporadically, e.g. during endoscopic examinations. (medicalwholesome.com)
  • Treatment of esophageal cancer is based on surgical operations. (medicalwholesome.com)
  • As part of esophageal cancer prevention, lifestyle modification is necessary. (medicalwholesome.com)
Benign2
  • The aneurysmal bone cyst (ABC) is a benign expansile osteoclastic giant cell-rich bony neoplasm composed of numerous blood-filled channels and cystic spaces. (medscape.com)
  • However, the proportion of neuroendocrine differentiation was found to be much higher in follow-up studies and it is now thought that 50% to 100% of all prostate neoplasms (including benign prostatic tissue) contain at least some neuroendocrine cells [3,5]. (cancernetwork.com)
Disease13
  • however, some patients remain at risk of relapse or death for many years after treatment of early-stage disease. (nih.gov)
  • BACKGROUND: The purpose of this study was to compare the rates of all-cause and breast cancer-specific mortality after breast-conserving surgery (BCS) only, BCS plus radiation therapy (RT), mastectomy, and the receipt of adjuvant tamoxifen in a large population-based cohort of older women with early-stage disease. (healthpartners.com)
  • [ 1 ] The disease remains elusive to effective screening approaches and in 80% of cases presents at an unresectable or incurable stage. (medscape.com)
  • The results of the biopsy and imaging studies provide physicians with an idea of the 'personality,' or stage, of the disease. (sarcomahelp.org)
  • The use of more reliable prognostic tools or staging systems may overcome this difficulty and a nonhistological prostate cancer staging system has already shown that patients with visceral involvement but minimal bone disease have the highest chance of responding to a combination of doxorubicin, mitomycin-C, and 5-fluorouracil. (cancernetwork.com)
  • This model of disease progression may be an important prognostic tool and have implications for the treatment of patients with stage D malignancy. (cancernetwork.com)
  • Cancer is a disease caused by the mutating cells in the body. (imedix.com)
  • Maraviroc tablets are contraindicated in patients with severe renal impairment or end-stage renal disease (ESRD) (CrCl less than 30 mL per minute) who are concomitantly taking potent CYP3A inhibitors or inducers. (drugs.com)
  • Staging of the disease followed by CAT scanning of the upper and lower abdomen and of the retroperitoneal space showed multiple, enlarged bilateral para-aortic, and mesenteric lymph nodes. (ispub.com)
  • Penile cancer is an aggressive and mutilating disease that affects self-esteem, with psychological and functional repercussions, which make rehabilitation and social reintegration difficult [ 7 ]. (clinmedjournals.org)
  • The disease-free survival (DFS) curves of 8th AJCC classification were well separated between all stages. (gnu.ac.kr)
  • Ironically, the manifestation of the disease with a syndrome can occasionally turn out to be a lifesaver albeit the cancer is normally incurable at this stage - but still treatable. (ronnyallan.net)
  • Others, such as esophageal or pancreatic cancer, MAY NOT cause symptoms until the disease has reached an advanced stage. (medlineplus.gov)
Colorectal cancer5
  • 2016. Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer. . (oregonstate.edu)
  • A total of 207 patients (Study Group n=54, Historical Group n=153) with metastatic colorectal cancer were enrolled. (medscimonit.com)
  • 5-Fluorouracil (5-FU) is widely applied in the treatment of various cancers, including colorectal cancer (CRC) [1,2]. (medscimonit.com)
  • Colorectal cancer is the fifth most prevalent cancer in China, after lung, gastric, esophageal, and liver cancers [2]. (medscimonit.com)
  • Colorectal Cancer Colorectal cancer is extremely common. (msdmanuals.com)
Risk Factors2
  • This document compiles updated information available on the definition, risk factors, evaluation methods, treatment and special situations in cancer patients with febrile neutropenia. (ijpsonline.com)
  • Few patients diagnosed with pancreatic cancer have identifiable risk factors. (medicinenet.com)
Mastectomy3
  • Compared with women receiving mastectomy, those receiving BCS without RT were twice as likely to die of breast cancer (adjusted hazards ratio [HR]=2.19, 95% confidence interval [CI], 1.51 to 3.18). (healthpartners.com)
  • Breast cancer mortality rates were similar between women receiving BCS plus RT and women receiving mastectomy (adjusted HR=1.08, 95% CI, 0.79 to 1.48). (healthpartners.com)
  • CONCLUSIONS: Our findings indicate that older women receiving BCS alone have higher rates of breast cancer death than those receiving BCS + RT or mastectomy and that the survival benefit from tamoxifen increases with increasing duration of treatment. (healthpartners.com)
Breast cancer8
  • RESULTS: We identified 1,837 women having operations for stage I or II breast cancer. (healthpartners.com)
  • Finally, EPB41L4A-AS2 inhibited breast cancer cell proliferation, migration and invasion and induced cell apoptosis in vitro. (cancerindex.org)
  • Breast Cancer Res Treat. (recurrenceonline.com)
  • RecurrenceOnline: an online analysis tool to determine breast cancer recurrence and hormone receptor status using microarray data, Breast Cancer Res Treat (2012). (recurrenceonline.com)
  • Dynamic classification using case-specific training cohorts outperforms static gene expression signatures in breast cancer, Int J Cancer (2015). (recurrenceonline.com)
  • INTRODUCTION: More than 70 common alleles are known to be involved in breast cancer (BC) susceptibility, and several exhibit significant heterogeneity in their associations with different BC subtypes. (lu.se)
  • Objective: To evaluate the presence of symptoms of anxiety and depression in women affected by breast cancer. (bvsalud.org)
  • Conclusion: Breast cancer causes significant psychological impact on women's lives and emotional distress, which varies at each stage of treatment, requiring differentiated assistance by the health team and psychological care throughout the process. (bvsalud.org)
LUNG9
  • Clin Lung Cancer , 14 (4), 425-432. (duke.edu)
  • Clin Lung Cancer 14, no. 4 (July 2013): 425-32. (duke.edu)
  • Currently the most important prognostic factor in lung cancer is the stage. (unint.eu)
  • Stage IV lung cancer, what treatments work for you? (mayoclinic.org)
  • I was diagnosed with stage IV lung cancer in January 2019. (mayoclinic.org)
  • Go to the Lung Cancer Support Group. (mayoclinic.org)
  • In March I was diagnosed with stage 4 Malignant Neoplasm Adenocarcinoma of the lung which is Non curable. (mayoclinic.org)
  • Boy do we have so much to contend with, lung cancer is so burdensome, so many decisions and trying to feel as well as can be. (mayoclinic.org)
  • Hello richcoleen: I have stage 4 Adenocarcinoma of the lung. (mayoclinic.org)
Symptoms3
  • Symptoms and signs of pancreatic cancer in its late stage include weight loss and back pain . (medicinenet.com)
  • The initial symptoms of pancreatic cancer are often quite nonspecific and subtle in onset. (medscape.com)
  • Other symptoms may be present depending on the site of cancer (eg, hoarseness in laryngeal cancer or abnormal vaginal bleeding in uterine cancer). (msdmanuals.com)
20211
Primary4
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • Metastatic adenocarcinoma presenting as isolated axillary lymphadenopathy in women is usually a manifestation of an occult breast primary cancer . (medscape.com)
  • There is consensus on the fact that surgery is the primary mode of treatment for pancreatic cancer. (medscape.com)
  • Surgery is the primary mode of treatment for pancreatic cancer. (medscape.com)
Surgery5
  • Surgery is the only potentially curative treatment modality for early-stage pancreatic cancer. (medscape.com)
  • Surgery is the initial therapy for stage I-IV fallopian tube cancers. (medscape.com)
  • RESULTS: Of 2572 patients undergoing rectal cancer surgery in 277 participating centres across 44 countries, 673 (26.2%) underwent chemoradiotherapy and surgery. (lu.se)
  • In some cases, painless jaundice may be a symptom of early pancreatic cancer that can be cured with surgery. (medicinenet.com)
  • Of 972 patients who had undergone surgery for PNET, excluding patients diagnosed with ENETS/World Health Organization 2010 grade 3 (G3), only 472 patients with accurate stage were included. (gnu.ac.kr)
Antigens1
  • Metastases, invasion of lymph nodes, and coupling of cancer-associated antigens did not significantly modify marker sensitivity. (unisr.it)
Survival Rate1
  • Results Poor discrimination in overall survival rate (OSR) was noted between AJCC 8th stage III and IV (p=0.180). (gnu.ac.kr)
Pancreatic cancers1
Liver3
  • Occasionally, the presence of pancreatic cancer is suggested by elevated liver transaminase, bilirubin, and alkaline phosphatase levels on testing performed for other purposes. (medscape.com)
  • At present, both the European Association for the Study of the Liver (EASL) [ 2 ] and the American Association for the Study of Liver Diseases (AASLD) [ 3 ] recommend transarterial chemoembolization (TACE) as the standard treatment option for patients with intermediate-stage (BCLC stage B) HCC. (hindawi.com)
  • Combination therapies have been researched for liver cancer, with synergistic effects [ 11 ], including PD-1 inhibitors plus lenvatinib and TACE plus lenvatinib [ 12 , 13 ]. (hindawi.com)
Mortality3
  • Despite recent therapeutic advances, febrile neutropenia is still a major cause of morbidity and mortality among cancer patients in Latin America and worldwide. (ijpsonline.com)
  • Trends in cancer incidence, mortality, and patient survival in the United States, as well as many other studies, are derived from this data bank. (cdc.gov)
  • Goals of the SEER Program Assembling and reporting, on a periodic basis, estimates of cancer inci- dence and mortality in the United States. (cdc.gov)
Methods2
  • Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. (lookformedical.com)
  • most registries use a mixture of tion with the cancer registry may be methods, and although active case raised by the owners. (who.int)
Serum2
  • Patients with advanced pancreatic cancer and weight loss have laboratory evidence of malnutrition (eg, low serum albumin or cholesterol level). (medscape.com)
  • Neoplasms containing cyst-like formations or producing mucin or serum. (lookformedical.com)
Incidence7
  • Both the incidence and the death rates for pancreatic cancer are increasing. (medscape.com)
  • With the dubious honor of having the highest per capita incidence of bladder cancer in the nation, Rhode Island represents a unique patient population. (urotoday.com)
  • Brazil is one of the countries with the highest incidence of penile cancer in the world [ 5 , 6 ] which may correspond to 2.1% of all neoplasms in men, being five times more prevalent in the North and Northeast regions [ 7 ], where most of the procedures are performed. (clinmedjournals.org)
  • Among these regions, Brazilian studies indicate that the State of Maranhão (Northeast of Brazil) has the highest incidence of penile cancer in Brazil, with an age-standardized incidence of 6.15 cases/100,000 habitants, with approximate statistics of one new case every 17 days [ 6 ]. (clinmedjournals.org)
  • Therefore, the Brazilian Penile Cancer Consensus argues that reducing the incidence of this cancer is possible by encouraging intimate hygiene education, neonatal circumcision, smoking cessation, vaccination against HPV among young people, and the use of condoms [ 4 ]. (clinmedjournals.org)
  • Monitoring annual cancer incidence trends to identify unusual changes in specific forms of cancer occurring in population subgroups defined by geo- graphic, demographic, and social characteristics. (cdc.gov)
  • Puerto Rico was selected as a participant to monitor cancer incidence in an industrially developing area with overall low cancer risk. (cdc.gov)
Metastatic3
  • Erlotinib has been approved by the FDA for use, in combination with gemcitabine, as a first-line treatment for locally advanced, unresectable, or metastatic pancreatic cancer. (medscape.com)
  • Diagnosed with Metastatic Neuroendocrine Cancer in 2010. (ronnyallan.net)
  • Accordingly, these researchers recommended considering gemcitabine-capecitabine as one of the standard first-line options in locally advanced and metastatic pancreatic cancer. (medscape.com)
Metastases1
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
Prostate2
Abnormal3
  • Cancer is the result of the uncontrolled growth of abnormal cells anywhere in the body. (medicinenet.com)
  • Sometimes the first indication is an abnormal laboratory test result (eg, anemia resulting from colon cancer). (msdmanuals.com)
  • Physicians must be aware of predisposing factors and must specifically ask about familial cancers, environmental exposures (including smoking history), and prior or present illnesses (eg, autoimmune disorders, previous immune-suppressing therapy, hepatitis B or hepatitis C infection, HIV infection, abnormal Papanicolaou test, human papillomavirus infection). (msdmanuals.com)
Factors1
  • The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause. (lookformedical.com)
Histologically1
Cervical2
  • IntroductionWomen with cervical cancer in the Nordic countries are increasingly undergoing pretreatment imaging by ultrasound, magnetic resonance imaging (MRI), positron emission tomography-computed tomography (PET-CT) or computed tomography, or sentinel lymph node procedure. (diva-portal.org)
  • The median number (range) of women with cervical cancer treated at each center annually was 32 (15-120). (diva-portal.org)