• Dietary polyphenols represent a large class of naturally occurring phenolic compounds which have been well investigated as antioxidants, radical scavengers and other health-promoting agents. (benthamscience.com)
  • Red wine polyphenols, which consisted of various powerful antioxidants such as flavonoids and stilbenes, have been implicated in cancer prevention and that promote human health without recognizable side effects. (lacienciadelvino.com)
  • Li and colleagues measured the level of polyphenols - a group of natural antioxidants linked to anti-cancer, anti-inflammatory, and anti-diabetic properties - of six brands of tea purchased from supermarkets. (medindia.net)
  • Currently, there is no established DRI (dietary reference intake) and the FDA prohibits manufacturers from making claims about polyphenols and their role as antioxidants. (forbes.com)
  • Grapes contain powerful antioxidants known as polyphenols. (medicalnewstoday.com)
  • When people incorporate sufficient levels of polyphenol-rich plant foods into their diets, it's thought that these antioxidants can counter excessive levels of free radicals. (discovermagazine.com)
  • He's also investigated these antioxidants' role in preventing and treating certain diseases, including cancer. (discovermagazine.com)
  • Frozen fruit and vegetables can be healthier, with higher levels of vitamins and cancer fighting antioxidants, than leafy 'fresh' produce. (dailymail.co.uk)
  • Honey contains an impressive amount of polyphenols, micronutrients that act as antioxidants and provide many health benefits. (indiatimes.com)
  • The main sources of antioxidants in rose tea are polyphenols . (healthline.com)
  • Antioxidants help prevent cell damage, and might even give you extra protection against heart disease , colon cancer, and skin irritation . (greatist.com)
  • Tea leaves are full of healthy antioxidants and contain substances that lower the risk of cancer, diabetes , and heart disease . (worldatlas.com)
  • There is no evidence that antioxidant supplements interfere with the therapeutic effects of chemotherapy agents, according to a recent systematic review of the use of antioxidants during chemotherapy, available in the May, 2007 issue of the journal Cancer Treatment Reviews. (news-medical.net)
  • Scientists at the University of Glasgow found that in the presence of lipid the ability of antioxidants, such as ascorbic acid (the active component of vitamin C), to protect against the generation of potential cancer-forming compounds in the stomach is less than when no lipids are present. (news-medical.net)
  • The phytochemicals in this diet have key anticarcinogenic and anti-cardiovascular disease properties, promote important antioxidants (eg, polyphenols, flavonoids), and are high in oleic acid and polyunsaturated fatty acids and low in monounsaturated fatty acids, which promote the anti-inflammatory, antithrombotic prostaglandin pathway. (medscape.com)
  • They warned however that the study does not call for women to increase alcohol consumption as a means of breast cancer prevention. (nutraingredients.com)
  • Dietary polyphenols have gained public interest in recent times due to their roles in the prevention of various diseases that implicate free radicals/reactive oxygen species. (frontiersin.org)
  • Suppression of in situ estrogen formation in the breast of postmenopausal women by aromatase inhibitors is considered to be a useful approach for prevention and treatment of breast cancer. (orlpedia.gr)
  • Before discussing or recommending a dietary or lifestyle pattern that may help prevent prostate cancer or inhibit its progression, it would seem prudent to touch on probability, which should inform discussions of the role of nutrition in the prevention of any disease. (medscape.com)
  • Thus, for the average US man, CVD prevention should take precedence over prostate cancer prevention, based on probability and cumulative research. (medscape.com)
  • Fortunately, most of what is known concerning lifestyle and dietary change for CVD prevention appears to directly apply to cancer prevention. (medscape.com)
  • The largest US and worldwide trials of pharmaceutical-based prostate cancer primary prevention exemplify the urgent need for a more proper and balanced perspective. (medscape.com)
  • For example, results of the Prostate Cancer Prevention Trial (PCPT) garnered attention plus controversy regarding the use of finasteride daily versus placebo to reduce the risk of prostate cancer. (medscape.com)
  • Within certain regions of the world population based studies have identified a possible role for green tea in the prevention of certain cancers, especially PCa. (breakawaymatcha.com)
  • Many potential mechanisms have been proposed including both antioxidant and pro-oxidant effects, but questions remain regarding the relevance of these mechanisms to cancer prevention. (thestemcellfoundation.com)
  • In the present review we will discuss the redox chemistry of the tea catechins and the current literature on the antioxidant and pro-oxidative effects of the green tea polyphenols as they relate to cancer prevention. (thestemcellfoundation.com)
  • They have been associated with prevention of cancer , heart disease , high blood pressure , and constipation . (medicalnewstoday.com)
  • 2007. Frontiers in polyphenols and cancer prevention. . (oregonstate.edu)
  • 2011. Dietary factors and epigenetic regulation for prostate cancer prevention. . (oregonstate.edu)
  • Whether you are a healthcare provider, a researcher, or just someone who wants to learn more about cancer prevention, we're here to help. (aicr.org)
  • Read real-life accounts of how AICR is changing lives through cancer prevention and survivorship. (aicr.org)
  • AICR is committed to putting what we know about cancer prevention into action. (aicr.org)
  • To help you live healthier, we've taken the latest research and made 10 Cancer Prevention Recommendations . (aicr.org)
  • Flaxseed's potential influence on breast , prostate, and other hormone-related cancers has led to an interest in its role for the prevention and survivorship of these cancers. (aicr.org)
  • Interest in flaxseed and cancer prevention often focuses on its ALA (alpha-linolenic acid) and lignans, although evidence is clearest regarding its role as a source of dietary fiber. (aicr.org)
  • An editorial by Huang summarizes some of the data on the role of nutrient intakes that are reported to modify genetic susceptibility to diseases such as cancer, with the expectation that this would provide a scientific basis for cancer prevention via dietary modification. (medscape.com)
  • Results Mean total polyphenol intake was the highest in Aarhus-Denmark (1786 mg/day in men and 1626 mg/day in women) and the lowest in Greece (744 mg/day in men and 584 mg/day in women). (lu.se)
  • Cereals, chocolate and dry legumes also contribute to the total polyphenol intake 67 . (bvsalud.org)
  • Chocolate is very rich in PPs, and a minor consumption of chocolate may significantly contribute to total polyphenol intake 68 . (bvsalud.org)
  • In one of the most well known examples, consumption of red wine, which contains the polyphenol resveratrol, has been associated with reduced risk of cardiovascular disease. (nutraingredients.com)
  • They investigated the effect of epigallocatechin gallate (EGCG), xanthohumol and resveratrol, substances present in significant concentrations in tea, beer and red wine, respectively, on the growth of a human breast cancer cell line, MCF-7. (nutraingredients.com)
  • Although resveratrol was believed to be a promising cancer chemopreventive agent from red wine, the search for other novel cancer chemopreventive polyphenols, like myricetin, is also of significance. (orlpedia.gr)
  • 4. Miksits M , Wlcek K , Svoboda M , Kunert O , Haslinger E , Thalhammer T , Szekeres T , Jäger W . Antitumor Activity of Resveratrol and its Sulfated Metabolites against Human Breast Cancer Cells. (orlpedia.gr)
  • El resveratrol, el cual es es el componente principal del vino tinto se ha estudiado extensamente por sus propiedades anticancerígenos, en esta revisión se centran en recoplilar los estudios sobre el resveratrol y sus actividades quimiopreventivas en el cáncer así como como de otros polifenoles preswentes en el vino como la procianidina B5 y la miricetina. (lacienciadelvino.com)
  • Laboratory studies have suggested that resveratrol may be able to slow or prevent the growth of tumors in lymph, liver, stomach, breast, colon, skin cancer , and leukemia . (medicalnewstoday.com)
  • The polyphenols in grapes, such as resveratrol, are thought to have antioxidant, lipid-lowering, and anti-inflammatory actions that may help reduce the risk of cardiovascular disease (CVD). (medicalnewstoday.com)
  • Trans-resveratrol is a polyphenol with great antioxidant action that reduces the oxidative stress. (bvsalud.org)
  • In addition, animal models have consistently shown that standardized green tea polyphenols when administered in drinking water delay the development and progression of PCa. (breakawaymatcha.com)
  • This review will present the available data for standardized green tea polyphenols in regard to PCa chemoprevention that will include epidemiological, mechanism based studies, safety, pharmacokinetics, and applicable clinical trials. (breakawaymatcha.com)
  • Known for their antioxidant properties, studies have reported a diet rich in polyphenols may offer protection against inflammation and chronic diseases, including cardiovascular disease, diabetes, and cancer. (forbes.com)
  • The nutrients in grapes may help protect against cancer, eye problems, cardiovascular disease, and other health conditions. (medicalnewstoday.com)
  • They are important components of the human diet because of their capacity to reduce the risk of chronic diseases such as cardiovascular disease and cancer. (scirp.org)
  • Interestingly, every prostate-cancer study with survival as the endpoint has found that most patients die of causes other than prostate cancer, mostly cardiovascular disease. (medscape.com)
  • Therefore, the possible merits of nutritional measures in preventing prostate cancer are compounded by their proven merits in preventing and managing cardiovascular disease. (medscape.com)
  • NME) comprises three highly integrated may be considered as the traditional pathways common to cancer, diabetes, groups: the Biomarkers Group (BMA), the domains of nutrition in cancer research and cardiovascular disease. (who.int)
  • However, as soon as the rural Chinese moved into cities and acquired the Western diet, a much higher incidence of diabetes, breast cancer, colon cancer, and cardiovascular disease was reported. (medscape.com)
  • Six hybrids were subjected to chromatographic analyses by HPLC for the determination of phytochemicals such as capsaicinoid, polyphenol, and vitamin C. The dynamics of ripening of 4 of the hybrids were also characterised. (hindawi.com)
  • Polyphenols are phytochemicals that occur naturally in plants. (forbes.com)
  • The seeds of the flax plant are packed with fiber and phytochemicals called lignans, compounds well studied for their anti-cancer activity. (aicr.org)
  • However, there is a huge gap between the perception that tea consumption is healthy and the actual amount of the healthful nutrients - polyphenols - found in bottled tea beverages. (medindia.net)
  • After a systematic review of the global scientific literature, AICR/WCRF analyzed how foods and their nutrients affect the risk of developing cancer. (aicr.org)
  • One constituent in particular, epigallocatechin-3-gallate also known as EGCG has been shown in cell culture models to decrease cell viability and promote apoptosis in multiple cancer cell lines including PCa with no effect on non-cancerous cell lines. (breakawaymatcha.com)
  • The present study found that the tea polyphenol epigallocatechin-3-gallate (EGCG) significantly inhibited PRODH and its regulated proteins, such as alpha-smooth muscle actin (alpha-SMA) expression in TNBC cells. (tmu.edu.tw)
  • 2010. (-)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells. . (oregonstate.edu)
  • 2009. Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies. . (oregonstate.edu)
  • Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition. (uni-heidelberg.de)
  • But researchers from the Universidade do Porto, Portugal found that such phenolic compounds could also fight breast cancer, the most common cancer among women in the European Union. (nutraingredients.com)
  • In colorectal cancer cells, myricetin inhibited the activity of matrix metalloproteinase-2 [11]. (orlpedia.gr)
  • Three different polyphenols, compounds found in wine, beer and tea, appear to significantly decrease breast cancer cells, according to new research from Portugal, which goes against previous findings showing that alcohol raises the risk of breast cancer. (nutraingredients.com)
  • All three polyphenolic compounds tested showed a significant effect, decreasing breast cancer cells' proliferation, and at concentrations that were not toxic to cells. (nutraingredients.com)
  • Further studies will be required before these compounds or the releveant beverages can be recommended to help prevent cancer. (nutraingredients.com)
  • Fruits and veggies provide us with powerful compounds called polyphenols that influence the body's inner rhythms. (discovermagazine.com)
  • In two out of three cases frozen fruit and vegetables scored better on antioxidant-type compounds - including Vitamin C, polyphenols, anthocyanins, lutein and beta-carotene. (dailymail.co.uk)
  • Consumption of these anti-oxidant compounds is considered beneficial in preventing cancer and supporting the working of the body, brain, skin and eyes. (dailymail.co.uk)
  • Background/Objectives Polyphenols are plant secondary metabolites with a large variability in their chemical structure and dietary occurrence that have been associated with some protective effects against several chronic diseases. (lu.se)
  • Among these secondary metabolites are vitamins and polyphenols. (discovermagazine.com)
  • Here's the thing: Even though you could type "polyphenols and nutrition" into your Pubmed search and find an abundance of articles supporting these alleged health benefits (about 130 pages worth), there is still so much we don't know and understand about polyphenols, including absorption, metabolism, and how much is too much. (forbes.com)
  • Coffee also has vasodilatory effects and contains antioxidant polyphenols, which reduce oxidative stress and modulate metabolism. (medscape.com)
  • To date, limited data exist on intake of polyphenols in populations. (lu.se)
  • The current cross-sectional analysis aimed at estimating dietary intakes of all currently known individual polyphenols and total intake per class and subclass, and to identify their main food sources in the European Prospective Investigation into Cancer and Nutrition cohort. (lu.se)
  • When dividing the subjects into three regions, the highest intake of total polyphenols was observed in the UK healthconscious group, followed by non-Mediterranean (non- MED) and MED countries. (lu.se)
  • Known as the French paradox, a low incidence of coronary heart disease despite substantial intake of saturated fats is thought to be due to a diet rich in polyphenols. (medicalxpress.com)
  • The rest had small amounts of polyphenols that Li said probably would carry little health benefit, especially when considering the high sugar intake from tea beverages. (medindia.net)
  • Intake of dietary isoflavones showed an association with advanced prostate cancer, but not early disease, according to a recent study in International Journal of Cancer. (nutraingredients.com)
  • Flavanone intake is inversely associated with esophageal cancer risk and may account, with vitamin C, for the protective effect of fruit, especially citrus fruit, on esophageal cancer. (greenmedinfo.com)
  • High fibre intake can also reduce the risk of certain cancers and heart disease. (myfashionlife.com)
  • Dietary B group vitamin intake and the bladder cancer risk: a pooled analysis of prospective cohort studies. (who.int)
  • Dietary intake of advanced glycation endproducts (AGEs) and cancer risk across more than 20 anatomical sites: A multinational cohort study. (who.int)
  • A growing body of scientific evidence shows that berry polyphenols' antioxidant capacity powerfully targets numerous degenerative diseases, from cancer and atherosclerosis to impaired glucose control and blood lipid abnormalities. (lifeextension.com)
  • Regular consumption of fish may reduce the risk of diseases such as asthma, prostate cancer and eyesight. (medindia.net)
  • Such damage can cause common non-infectious diseases like cancer, hypertension, Parkinson's and diabetes, which are among the leading causes of U.S. deaths. (discovermagazine.com)
  • You can consider polyphenols even as lifespan-extending dietary components because with less non-communicable diseases, someone can live longer," he says. (discovermagazine.com)
  • Liver fibrosis is a serious health concern which leads to liver diseases such as cirrhosis and primary liver cancer having a worldwide mortality of approximately 1.5 million deaths per year 23 . (nature.com)
  • Free radicals may play a part in cancer, heart disease, stroke, and other diseases of aging. (news-medical.net)
  • Polyphenols exert preventive activity against infectious and degenerative diseases including oral diseases. (bvsalud.org)
  • Polyphenols (PPs) exert preventive activity against infectious and degenerative diseases and may also help prevent oral diseases via various mechanisms 58 . (bvsalud.org)
  • According to a hypothesis, polyphenol (PP) activity against several forms of cancer, proliferative diseases, inflammation and neurodegeneration is mainly exerted through the inhibiting and modulating activities against a wide range of receptors, enzymes and transcription molecules 88 . (bvsalud.org)
  • Cancer is a notable deadly disease involving such as fluorouracil, methotrexate and several other diseases. (who.int)
  • Health conditions* that could affect gut and immune health such as gastrointestinal diseases [including, but not limited to diverticulitis, ulcerative colitis, Crohn's disease, or coeliac disease, colostomy], type 1 or type 2 diabetes, cancer, renal or liver diseases in the last 12 months. (who.int)
  • This chronic inflammation can increase our lifetime risk for obesity , type 2 diabetes , heart disease, and some forms of cancer as well as other autoimmune diseases. (medscape.com)
  • 2011). Larger quantities of free radicals (reactive disease, diabetes, chronic respiratory diseases, and oxygen species [ROS]) present in the cigarette cancer (WHO, 2012). (bvsalud.org)
  • In addition, consuming tea can help reduce joint inflammation due to the presence of polyphenols. (worldatlas.com)
  • Curcumin, a natural polyphenolic compound derived from turmeric (Curcuma longa L), has proven to be a modulator of multiple intercellular signalling pathways linked to inflammation, to proliferation, growth, invasion, drug sensitivity, angiogenesis and metastasis of cancer cells. (researchgate.net)
  • Cocoa polyphenols tend to reduce inflammation by regulating proinflammatory mediators and controlling processes that oxidize low density lipids (LDL) in the development of atherosclerosis 73 . (bvsalud.org)
  • The results "add support and meaning to epidemiological studies that relate consumption of certain beverages with a lesser incidence and prevalence of cancer," ​ said the researchers. (nutraingredients.com)
  • The findings from these data bases suggest that while dietary polyphenols may not replace the need for the existing therapies in the management of BPH, they hold promise in BPH management which could be explored by researchers working in this field. (frontiersin.org)
  • Nevertheless, the use of diet and dietary supplements for reducing the risk of developing prostate cancer or for treating prostate cancer continues to engage the interest of patients and researchers. (medscape.com)
  • In prostate cancer cases, verses controls, the researchers found plasma concentrations of lutein, lycopene, α-carotene, β-carotene and selenium were significantly reduced. (polyphenols-site.com)
  • The results showed, the researchers wrote, "That the plasma nutriome could be a useful diagnostic of prostate cancer risk. (polyphenols-site.com)
  • After consuming a blend of açaí polyphenols, researchers recorded a three-fold increase in antioxidant capacity in the blood of healthy human volunteers. (lifeextension.com)
  • Researchers have found that many of the increasingly popular beverages included in the study contain fewer polyphenols than a single cup of home-brewed green or black tea. (medindia.net)
  • Texas A&M researchers have found a direct link between muscle contraction and a reduction in breast cancer. (livingfuel.com)
  • Consumption of a green tea extract has been suggested to reduce rates of cancer in certain indiviuals while reducing levels of the cancer biomarker prostate-specific antigen (PSA), say researchers. (nutraingredients.com)
  • Long-term use of vitamin C and E supplements do not increase the risk of cancer, while vitamin C may offer some colorectal benefits, according to a new analysis from Harvard researchers. (nutraingredients.com)
  • Vitamin D deficiency may be an indicator in the diagnosis of aggressive prostate cancer, according to researchers. (nutraingredients.com)
  • Consumption of more than four cups of coffee a day may reduce the risk of prostate cancer recurrence and progression, suggest researchers. (nutraingredients.com)
  • Men with prostate cancer can significantly improve their survival chances by switching from diets rich in animal fat and carbohydrates to ones rich in vegetable fats, say researchers. (nutraingredients.com)
  • Inherent gender differences - instead of more sun exposure - may be one reason why men are three times more likely than women to develop certain kinds of skin cancer, say researchers at Ohio State University Medical Center. (news-medical.net)
  • This review is meant point out understudied areas and stimulate research on the topic with the hope that insights into the mechanisms of cancer preventive activity of tea polyphenols will result. (thestemcellfoundation.com)
  • The team reported that radiation-induced micronucleus and nuclear buds frequencies, both dangerous signs, were significantly higher in prostate cancer patients with low selenium or low lycopene levels compared to the controls. (polyphenols-site.com)
  • Each group evaluated the sensory qualities of a geographically paired organic (OW) and conventional wine (CW) and an artificially colored white wine placebo (PW) with significantly differing total polyphenol concentrations (TP). (scirp.org)
  • This establishes a conundrum where dietary polyphenols are healthful but potentially unpalatable.We recruited and randomized 18 female participants (21 - 50 y) to one of five groups (3 - 4 per group). (scirp.org)
  • Coffee, tea, and fruits were the most important food sources of total polyphenols. (lu.se)
  • Prostate cancer rates were lower in men who regularly consumed "colorful fruits and vegetables," according to new research from the University of South Australia. (polyphenols-site.com)
  • A diet that is rich in fruits and vegetables has been linked to a reduced risk of various conditions, including heart disease, diabetes, cancer, and obesity . (medicalnewstoday.com)
  • People should ideally eat local, in-season fruits and vegetables to get the most out of polyphenols, says Manuel Suárez, a biochemist at the Universitat Rovira i Virgili in Tarragona, Spain. (discovermagazine.com)
  • Since polyphenols also play an important role in the sensory qualities of fruits and wines particularly involving astringency and bitterness, there may be differences that affect sensory perceptions of wine. (scirp.org)
  • Polyphenols (PPs) are reactive metabolites abundant in plant derived foods, especially fruits, seeds and leaves. (bvsalud.org)
  • Analysis of a cancer registry in the United States, which included men with prostate cancer, showed that patient-clinician information engagement leads to increased consumption of fruits and vegetables by cancer patients. (medscape.com)
  • The experimental data indicated that the molecular mechanisms of fatty acid synthase gene suppression by tea polyphenols (EGCG, theaflavins) may invite down-regulation of EGFR/PI3K/Akt/Sp-1 signal transduction pathways. (nih.gov)
  • K. Martin and K. Rasmussen, "Comparison of Sensory Qualities of Geographically Paired Organic and Conventional Red Wines from the Southwestern US with Differing Total Polyphenol Concentrations: A Randomized Pilot Study," Food and Nutrition Sciences , Vol. 2 No. 10, 2011, pp. 1150-1159. (scirp.org)
  • More recent studies have focused on the biological activity of various extracts of cocoa or of waste materials from the chocolate industry, such as cocoa bean husk, which is known to contain high concentrations of polyphenols. (bvsalud.org)
  • The health protective attributions of them are mainly associated with preventing cancer through inhibiting certain enzymes and suppressing angiogenesis [ 17 ]. (hindawi.com)
  • Polyphenols eventually interact with specific enzymes or receptors and can aid in vital biological mechanisms: For example, they have been reported to support the P53 protein, also called the ' guardian of the genome, ' in suppressing tumor growth. (discovermagazine.com)
  • Lab tests have indicated that cinnamon extracts may detoxify enzymes linked to colon cancer, protecting against further growth of cancer cells. (indiatimes.com)
  • Red raspberries have antioxidant effects that play a minor role in the killing of stomach and colon cancer cells. (wikipedia.org)
  • In Africa, no colon cancer. (oneradionetwork.com)
  • He died of colon cancer. (oneradionetwork.com)
  • 2017. A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells. . (oregonstate.edu)
  • The burden of colon cancer attributable to modifiable factors-The Norwegian Women and Cancer Study. (who.int)
  • This team's findings were published in two papers featured in Cancers. (polyphenols-site.com)
  • Asked whether the team's findings could be extended to other cancers, Deo said, "There are research studies reinforcing the role of selenium and lycopene in prostate cancer, but limited evidence in other cancers. (polyphenols-site.com)
  • Find out how these and other findings confirm berry polyphenols' unrivalled capacity to blunt free radical damage and thwart degenerative disease. (lifeextension.com)
  • These findings support the targeting of the PRODH signaling pathway as a potential therapeutic strategy in preventing cancer cell metastasis. (tmu.edu.tw)
  • Li pointed out that in addition to the low polyphenol content, bottled commercial tea contains other substances, including large amounts of sugar and the accompanying calories that health-conscious consumers may be trying to avoid. (medindia.net)
  • A low-fat diet in combination with supplementation with omega-3 rich fish oil may be associated with lower levels of pro-inflammatory substances and reduced cell progression scores in men with prostate cancer, research has suggested. (nutraingredients.com)
  • The largest clinical trial ever conducted on the use of dietary supplements to prevent cancer was the selenium and vitamin E supplementation randomized trial (SELECT). (medscape.com)
  • The objective of the present work is to investigate capsaicinoid, polyphenol, and vitamin C content in six hybrids of chili pepper (Bandai, Beibeihong, Lolo, Chili 3735, Fire Flame, and Star Flame) using recently developed liquid chromatographic method in the determinations. (hindawi.com)
  • The supposed anti-cancer effects of vitamin E have been long suggested. (nutraingredients.com)
  • Frozen carrots had three times the lutein and double the beta-carotene, while they were also higher in Vitamin C and polyphenols. (dailymail.co.uk)
  • The Chester study found levels of Vitamin C and polyphenols were much higher in frozen blueberries and green beans. (dailymail.co.uk)
  • With the aid of NMR technology, fundamental understanding of the polyphenol chemistry and reactivity has also been gradually disclosed, which sheds light on a better understanding of the structure-property relationship of polyphenols. (benthamscience.com)
  • Xanthohumol, found in beer, was the most potent polyphenol over breast cancer cell growth: it showed its effect more rapidly and at a lower concentration than the others. (nutraingredients.com)
  • Red wine polyphenols were found to be potent aromatase inhibitors, indicating potential treatment of breast cancer, since aromatase plays an important role in the carcinogenesis of breast cancer. (orlpedia.gr)
  • It was indicated that myricetin had a potent antioxidant capacity [7]] and suppressed several cancers 8, 9, 10, 11]. (orlpedia.gr)
  • In plants, polyphenols contribute to resistance to pathogens due to their potent astringency and function as phytoalexins. (scirp.org)
  • Although nutrition plays a role in the development of prostate cancer , no specific diet can prevent or eradicate this disease. (medscape.com)
  • One looked at diet and prostate cancer risk , the other examined levels of lycopene and selenium in such patients undergoing radiation therapy. (polyphenols-site.com)
  • The authors note that, "Many epidemiological and laboratory studies provided persuasive evidence that diet, genetic factors, and lifestyle were the major contributory factors of prostate cancer. (polyphenols-site.com)
  • Genetic factors combined with a high-fat diet (HFD) could lead to the spread of prostate cancer to other sites in the body, according to recent mouse data. (nutraingredients.com)
  • The AICR Lifestyle & Cancer Symposium addresses the most current and consequential issues regarding diet, obesity, physical activity and cancer. (aicr.org)
  • The Annual AICR Research Conference is the most authoritative source for information on diet, obesity, physical activity and cancer. (aicr.org)
  • Using two to four days of a fasting-mimicking diet (FMD) in patients undergoing chemotherapy for various cancer diagnoses, patients experienced protection from the toxicity of treatments. (mindbodygreen.com)
  • Other aspects of diet may increase prostate cancer risk. (medscape.com)
  • No studies have indicated that these diet recommendations would be of benefit in altering the growth of an existing cancer. (medscape.com)
  • Inflammatory potential of diet and pancreatic cancer risk in the EPIC study. (who.int)
  • However, the ongoing China Project from Cornell University evaluated approximately 6500 people and demonstrated an association that the consumption of the Asian diet in rural China protected against many of the cancers we see in Western civilization. (medscape.com)
  • Baseline and lifetime alcohol consumption and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC). (who.int)
  • Tea consumption and risk of bladder cancer in the Bladder Cancer Epidemiology and Nutritional Determinants (BLEND) Study: Pooled analysis of 12 international cohort studies. (who.int)
  • The recent progress in studies on cancer demonstrated chemopreventive activities of red wine polyphenol extracts and fractions as well as other red wine polyphenols [1]. (orlpedia.gr)
  • Red wine polyphenol extracts and fractions were reported to delay tumor onset in transgenic mice, inhibit azoxymethane (AOM) induced intestinal carcinogenesis by modulation of gene expression, inhibit epidermal growth factor induced the proliferation of transformed colon epithelial cells by modulation of activation of mitogen-activated protein kinases and show selective cytotoxicity against MCF-7 breast cancer cells. (orlpedia.gr)
  • Supported by above exciting evidence, further investigation on cancer chemopreventive activities of red wine polyphenol extracts and fractions are strongly recommended [1]. (orlpedia.gr)
  • Diets rich in polyphenols are thought to reduce the risk of certain types of cancer, heart disease, and type 2 diabetes, as well as protect your brain from degenerative disease ( 11 , 12 , 13 ). (healthline.com)
  • Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine. (uni-heidelberg.de)
  • Pilot study evaluating broccoli sprouts in advanced pancreatic cancer (POUDER trial) - study protocol for a randomized controlled trial. (uni-heidelberg.de)
  • Esablishment of hypoxia induction in an in vivo animal replacement model for experimental evaluation of pancreatic cancer. (uni-heidelberg.de)
  • Triptolide inhibits hypoxia-induced EMT and stem-like features in pancreatic cancer by downregulation of NF-kB signaling. (uni-heidelberg.de)
  • Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication. (uni-heidelberg.de)
  • The novel c-Met inhibitor cabozantinib overcomes gemcitabine resistance and stem-cell signaling in pancreatic cancer. (uni-heidelberg.de)
  • The previous hypothesis that red wine had stronger anti-cancer activities than white wine was confirmed by the difference in inhibition of aromatase activity[2, 3]. (orlpedia.gr)
  • However, the role of these polyphenols in the management of BPH and their mechanisms of action are yet to be reported. (frontiersin.org)
  • They could someday deliver innovative treatments for conditions like cancer and diabetes. (discovermagazine.com)
  • Gestational diabetes and risk of breast cancer before age 55 years. (who.int)
  • 2007. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. . (oregonstate.edu)
  • Circulating inflammatory biomarkers, adipokines and breast cancer risk-a case-control study nested within the EPIC cohort. (who.int)
  • Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability. (news-medical.net)
  • Perhaps the word "polyphenol" means little to you, but they certainly mean a lot to your health. (medicalxpress.com)
  • The health benefits of grades include helping boost heart health, preventing cancer, managing blood pressure, and protecting the eyes. (medicalnewstoday.com)
  • These are colored pigments that are associated with good urinary tract and eye health, improved memory, healthy aging, and a lower risk of some cancers ( 4 , 14 , 15 , 16 , 17 ). (healthline.com)
  • Another health benefit of steel cut oats is that they have polyphenols galore. (greatist.com)
  • Better knowledge of dietary polyphenols could offer a very economical public health intervention in maintaining oral health. (bvsalud.org)
  • In an interview study from the United Kingdom, Avery et al found that over half of men diagnosed with prostate cancer reported making dietary changes, primarily to promote general or prostate health or to facilitate coping. (medscape.com)
  • These observations suggest important implications on human health should EA be prescribed as a chemotherapeutic agent or a preventative dietary supplement for cancer. (cdc.gov)
  • K. R. Martin and C. Appel, "Polyphenols as Dietary Supplements: A Double-Edged Sword," Nutrition and Dietary Supplements, Vol. 2010, No. 2, 2009, pp. 1-12. (scirp.org)
  • I. Lesschaeve and A. Noble, "Polyphenols: Factors Influencing Their Sensory Properties and Their Effects on Food and Beverage Preferences," American Journal of Clinical Nutrition, Vol. 81, No. 1, 2005, pp. 330S-335S. (scirp.org)
  • Cancer Update Program - unifying research on nutrition, physical activity and cancer. (aicr.org)
  • AICR champions research that increases understanding of the relationship between nutrition, lifestyle, and cancer. (aicr.org)
  • A particular emphasis expertise to identify causal links between of NME is based on three major research is placed on cancer types that have nutrition, metabolic factors, and cancer. (who.int)
  • Biomarkers of the transsulfuration pathway and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. (who.int)
  • It has also been demonstrated that myricetin exerted protective effects against two-stage skin tumorigenesis [9] and inhibited the growth of A549 lung cancer cells [10]. (orlpedia.gr)
  • It has been suggested that the inhibition of growth and suppression of lipogenesis in MCF-7 breast cancer cells may be through down-regulation of fatty acid synthase gene expression in the nucleus and stimulation of cell energy expenditure in the mitochondria. (nih.gov)
  • The results demonstrated that PRODH induced epithelial-mesenchymal transition in cancer cells and increased cell proliferation. (tmu.edu.tw)
  • The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells. (oregonstate.edu)
  • They also decrease growth and increase self-destruction of cancer cells. (aicr.org)
  • Sulforaphane and TRAIL induce a synergistic elimination of advanced prostate cancer stem-like cells. (uni-heidelberg.de)
  • Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cancer stem-like cells acquire pronounced migratory potential. (uni-heidelberg.de)
  • often thought to protect cells from damage by oxygen, mutations, and cancer. (msdmanuals.com)
  • Human Papillomavirus (HPV) Infection Human papillomavirus (HPV) can be sexually transmitted and causes changes in cells, which can lead to genital warts or to precancer or cancer of the cervix, vagina, vulva, anus, or throat. (msdmanuals.com)
  • In addition, "There is strong evidence that being overweight and tall increases the risk of prostate cancer. (polyphenols-site.com)
  • Low selenium levels could lead to a higher risk of prostate cancer, a study has concluded. (nutraingredients.com)
  • A raft of industry and academic experts have slammed the publication of a recent study claiming to 'confirm' a link between long-chain omega-3s and an increased risk of prostate cancer - arguing that the authors conclusions are overblown and. (nutraingredients.com)
  • The number and characteristics of these phenol structures underlie the unique physical, chemical, and biological (metabolic, toxic, therapeutic, etc.) properties of particular members of the polyphenol class. (medicalxpress.com)
  • PG) polyphenols on metabolic disorders. (news-medical.net)
  • The Section profiling techniques to implement an cancers, as well as hormone-related combines large-scale population-based integrated, multidisciplinary programme cancers, such as breast cancer and studies with laboratory and biostatistical of research. (who.int)
  • Few studies have looked at the association between red wine and cancer risk in humans, but it has been shown that high intakes of alcohol on a consistent basis can increase the risk of cancer. (medicalnewstoday.com)
  • 2. Chen S, Sun XZ, Kao YC, Kwon A, Zhou D, Eng E. Suppression of breast cancer cell growth with grape juice. (orlpedia.gr)
  • A polyphenol-rich supplement containing broccoli, green tea, tumeric, and pomegranete - a combination known as pomi-t - could have significant clinical benefits for men with prostate cancer, according to new data. (nutraingredients.com)
  • The cancer-chemopreventive property of pomegranate juice and the chemotherapeutic effects against prostate cancer in humans has been reported as well 12 . (nature.com)