• amino
  • 23. The method of claim 20, further comprising adding an agglomerating agent to a plurality of nanoparticles, wherein the agglomerating agent is a salt or an amino acid. (patentsencyclopedia.com)
  • The 3FP protein domain has no enzymatic activity and is typically between 60-74 amino acid residues long. (wikipedia.org)
  • The proteins are typically 60-74 amino acid residues long, though some have additional N- or C-terminal extensions. (wikipedia.org)
  • Renin activates a circulating liver derived prohormone angiotensinogen by proteolytic cleavage of all but its first ten amino acid residues known as angiotensin I. ACE (Angiotensin converting enzyme) then removes a further two residues, converting angiotensin I into angiotensin II. (wikipedia.org)
  • sodium
  • Gain-of-function missense mutations in the brain type-I sodium channel Na V 1.1 are a primary cause of generalized epilepsy with febrile seizures plus. (jneurosci.org)
  • Mutations in the peripheral sodium channel Na V 1.7 cause familial pain syndromes. (jneurosci.org)
  • 50% in the transmembrane domains of human sodium channel α subunits and those of the simplest multicellular eukaryotes. (jneurosci.org)
  • 70%, knock-out of any of the three sodium channel α subunit genes expressed primarily in adult brain ( SCN1A , SCN2A , and SCN8A ) is lethal, demonstrating that each channel performs some nonredundant function. (jneurosci.org)
  • Stimulation by AII of the adrenal cortex to release aldosterone, a hormone that acts on kidney tubules, causes sodium and chloride ions retention and potassium excretion. (wikipedia.org)
  • Sodium is a "water-holding" ion, so water is also retained, which leads to increased blood volume, hence an increase in blood pressure. (wikipedia.org)
  • chronic
  • Studies of genetic forms of epilepsy, chronic pain, and migraine caused by mutations in ion channels have given crucial insights into molecular mechanisms, pathogenesis, and therapeutic approaches to complex neurological disorders. (jneurosci.org)
  • Because of the importance of their functions and the complexity of their structures, these two ion channels are targets for numerous mutations that cause diseases of hyperexcitability, including epilepsy, migraine, chronic pain, periodic paralysis, and cardiac arrhythmia. (jneurosci.org)
  • molecular
  • We have used the patch-clamp technique in combination with molecular techniques to define the ion channels involved in the outward current and to study the presence of Ca v in JG cells and their possible interaction with the secretory process. (ahajournals.org)