• osteoporosis
  • Synthetic analogues of calcitonin are of particular interest in the treatment of osteoporosis , a disease characterized by the thinning of bones that arises from increased bone resorption or decreased bone formation . (britannica.com)
  • Calcitonin injection is currently not approved for the treatment of osteoporosis but is sometimes prescribed for people who have fractures of the vertebrae, mainly to relieve pain. (womenshealthmatters.ca)
  • The agency also concluded that the benefits of calcitonin-containing medicines did not outweigh their risks in the treatment of osteoporosis and that they should no longer be used for this condition. (emaxhealth.com)
  • CHMP concluded that the benefits of calcitonin for osteoporosis did not exceed the risks. (emaxhealth.com)
  • In addition to banning its use for osteoporosis, the CHMP recommended that calcitonin should be administered for no more than four weeks to prevent acute bone loss resulting from sudden immobilization, and normally for no more than three months to treat Paget's disease. (emaxhealth.com)
  • Calcitonin may be useful in treating various bone disorders including, but not limited to, osteoporosis and Paget's disease. (google.co.uk)
  • gene
  • Calcitonin is formed by the proteolytic cleavage of a larger prepropeptide, which is the product of the CALC1 gene (CALCA). (wikipedia.org)
  • The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). (wikipedia.org)
  • fishes
  • In birds, fishes, and other nonmammalian vertebrates , calcitonin is secreted by cells of the glandular ultimobranchial bodies. (britannica.com)
  • vasoactive
  • Calcitonin levels may also be increased in association with lung cancer and certain tumours of the pancreas , namely insulinoma (an insulin -secreting tumour) and VIPoma (a vasoactive intestinal polypeptide -secreting tumour). (britannica.com)
  • proteins
  • He also developed novel technologies, in particular intestinal patches, for oral delivery of proteins such as insulin and calcitonin. (wikipedia.org)
  • phosphate
  • Calcitonin seems to have an acute effect in chronic renal failure which may not operate by arresting bone resorption but is dependent on the plasma phosphate concentration. (bmj.com)