AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth Care
Mitral Valve InsufficiencyMitral ValveAortic Valve InsufficiencyTricuspid Valve InsufficiencyPulmonary Valve InsufficiencyMitral Valve ProlapseVenous ValvesAortic ValveHeart Valve DiseasesMitral Valve StenosisHeart Valve Prosthesis ImplantationCalcinosisCardiac Surgical ProceduresHeart Valve ProsthesisMitral Valve AnnuloplastyHeartVascular CalcificationAortic Valve StenosisChordae TendineaeTreatment OutcomeAdrenal InsufficiencyTricuspid ValveBioprosthesisCalcification, PhysiologicPulmonary ValveEchocardiographyHeart RateRheumatic Heart DiseaseRenal InsufficiencyVenous InsufficiencyEchocardiography, TransesophagealExocrine Pancreatic InsufficiencyEchocardiography, Three-DimensionalCardiac Valve AnnuloplastyPlacental InsufficiencyHeart Defects, CongenitalPhonocardiographyEndocarditis, BacterialEchocardiography, Doppler, ColorEndocarditisHeart FailureHeart AtriaEchocardiography, DopplerHeart DiseasesDermatan SulfateEncyclopedias as TopicGlycosaminoglycansChondroitinHeart Sounds
RegurgitationStenosisAnnularCardiacEchocardiographyChordaeProlapseCongenitalMyocardialAbnormality of the mitral valveTricuspid valveAtrioventricularApparatusAnnulusChronicLeafletDiseaseTranscatheter mitralDilatationMurmurRegurgitantPatientsLeft atrialRespiratory insufficiencyAtrialAnterior and posteriorOutflowProstheticEndocarditisAcuteTissueReplacementAortaStructuralSystolePercutaneousDysfunctionClinicalPulmonic valvePulmonary valve
Regurgitation27
  • Treatment of mitral regurgitation (MR) associated with severe mitral annular calcification (MAC) is challenging due to the high risk of fatal atrioventricular groove disruption and significant paravalvular leak. (nih.gov)
  • A prospective, multicenter, single-arm adaptive design study to evaluate the safety and effectiveness of transcatheter mitral valve replacement with the Edwards SAPIEN M3 system in patients with symptomatic, at least 3+ mitral regurgitation for whom commercially available surgical or transcatheter treatment options are deemed unsuitable. (edwards.com)
  • Mitral regurgitation (MR) etiology can be categorized into primary or secondary. (edwards.com)
  • The ENCIRCLE trial is studying the SAPIEN M3 system in patients with symptomatic, at least 3+ MR of primary or secondary etiology and Carpentier functional classifications Type I, II, IIIa or IIIb mitral regurgitation. (edwards.com)
  • Mitral regurgitation may result from many processes. (health.am)
  • Rheumatic disease is associated with a thickened valve with reduced mobility and often a mixed picture of stenosis and regurgitation. (health.am)
  • In developed countries, more common causes of mitral regurgitation include myxomatous degeneration (eg, mitral valve prolapse with or without connective tissue diseases such as Marfan's syndrome), infective endocarditis, and subvalvular dysfunction (due to papillary muscle dysfunction or ruptured chordae tendineae). (health.am)
  • Cardiac tumors, chiefly left atrial myxoma, are a rare cause of mitral regurgitation. (health.am)
  • Mitral regurgitation leads to left atrial enlargement and may cause subsequent atrial fibrillation. (health.am)
  • Mitral regurgitation may predispose to infective endocarditis. (health.am)
  • Nonrheumatic mitral regurgitation may develop abruptly, such as with papillary muscle dysfunction following myocardial infarction , valve perforation in infective endocarditis, or ruptured chordae tendineae in mitral valve prolapse. (health.am)
  • In acute mitral regurgitation, patients are in sinus rhythm rather than atrial fibrillation and have little or no enlargement of the left atrium, no calcification of the mitral valve, no associated mitral stenosis , and in many cases little left ventricular dilation. (health.am)
  • Mitral Regurgitation Mitral regurgitation (MR) is incompetency of the mitral valve causing flow from the left ventricle (LV) into the left atrium during ventricular systole. (msdmanuals.com)
  • Pulmonic Regurgitation Pulmonic (pulmonary) regurgitation (PR) is incompetency of the pulmonic valve causing blood flow from the pulmonary artery into the right ventricle during diastole. (msdmanuals.com)
  • An abnormality of the mitral leaflets, mitral annulus, chordae tendineae, papillary muscles, left atrium, or left ventricle can lead to mitral regurgitation. (doctorlib.info)
  • Cardiac catheterization reveals mitral regurgitation with increased left ventricular end-diastolic volume and pressure, increased atrial pressure and PAWP, and decreased cardiac output. (doctorlib.info)
  • Rheumatic heart disease (RHD) is the major sequel and is characterized by valvar lesions that can cause regurgitation and/or stenosis mainly in mitral and aortic valves. (fortunejournals.com)
  • In the next slide you can see that there is, perhaps, moderate aortic insufficiency and moderate mitral regurgitation, as well. (medscape.com)
  • Here is a continuous-wave Doppler of the mitral regurgitation jet that you saw. (medscape.com)
  • An insufficiency of the aortic valve, leading to regurgitation (backward flow) of blood from the aorta into the left ventricle. (nih.gov)
  • New innovations have been directed toward the 2 most frequent forms of valvular heart disease in the industrialized West: aortic stenosis and mitral regurgitation, which account for more than 70% of the cases of acquired valve disease in the United States and Europe (see the table below). (medscape.com)
  • Investigations into the current management of patients with valvular heart disease in Europe and the United States showed that as many as one third of elderly patients with severe symptomatic aortic stenosis, and a similar number of patients with mitral regurgitation, were not referred for surgical management by the attending practitioner. (medscape.com)
  • The condition can lead to various valvular heart problems such as regurgitation and calcification of the aortic valve and the mitral valve. (hxbenefit.com)
  • Pavan Atluri, MD, director of minimally invasive and robotic cardiac surgery at Penn Medicine, reviews advantages of minimally invasive techniques for mitral regurgitation. (pennmedicine.org)
  • Thourani concluded that the Trilogy system provides the first dedicated transcatheter aortic valve replacement options "for symptomatic patients with moderate to severe or severe aortic regurgitation or at high risk for surgery and is well positioned to become the preferred therapy upon approval for this population. (medscape.com)
  • Off-label use of transcatheter valves for AR has been associated with "higher rates of complications, including paravalvular regurgitation and embolization," he noted. (medscape.com)
  • Exclusion criteria included an aortic root diameter greater than 5 cm, a previous prosthetic aortic valve, mitral regurgitation greater than moderate, or coronary artery disease requiring revascularization. (medscape.com)
Stenosis35
  • Increased hydrostatic pressure leading to pulmonary edema may result from many causes, including excessive intravascular volume administration, pulmonary venous outflow obstruction (eg, mitral stenosis or left atrial [LA] myxoma), and LV failure secondary to systolic or diastolic dysfunction of the left ventricle. (medscape.com)
  • Type IIIa refers to mitral leaflets that are restricted in both systole and diastole - including leaflets that are thickened and/or calcified due to rheumatic heart disease or stenosis. (edwards.com)
  • Calcification of the mitral valve is less common than in pure mitral stenosis . (health.am)
  • Mitral stenosis is narrowing of the mitral orifice that impedes blood flow from the left atrium to the left ventricle. (msdmanuals.com)
  • Most often, valvular stenosis or insufficiency. (msdmanuals.com)
  • In mitral stenosis, mitral valve leaflets become thickened and immobile and the mitral orifice becomes narrowed due to fusion of the commissures and the presence of shortened, thickened and matted chordae. (msdmanuals.com)
  • Occasionally, mitral stenosis is congenital or occurs after radiation therapy. (msdmanuals.com)
  • MR) may coexist with mitral stenosis. (msdmanuals.com)
  • Patients with mitral stenosis due to rheumatic fever may also have lesions of the aortic or tricuspid valve or both. (msdmanuals.com)
  • Acquired stenosis of the aortic valve, which affects adults, is most often caused by calcification of the leaflets themselves and is considered an age-related or degenerative process. (medscape.com)
  • Postrheumatic aortic stenosis is another common cause of acquired aortic stenosis, and is a result of remote infection from group A streptococci that triggers an autoimmune process resulting in scarring of the valve leaflets. (medscape.com)
  • The pathologic findings, clinical symptoms, and treatment are similar to degenerative aortic stenosis in trileaflet valves. (medscape.com)
  • A gradient of between 20 and 40 mm Hg is considered moderate, and more than 40 mm Hg severe aortic stenosis, according to American Heart Association guidelines. (medscape.com)
  • See also Aortic Stenosis , Pediatric Valvar Aortic Stenosis , Pediatric Rheumatic Heart Disease , and Pathology of Rheumatic Heart Disease . (medscape.com)
  • [ 3 ] Degenerative aortic stenosis is currently the most common indication for valve surgery, as the population ages and newer techniques, such as minimally invasive surgery and transcutaneous methods, become available. (medscape.com)
  • At present, the most common cause of valve replacement in the United States is aortic stenosis secondary to calcification. (medscape.com)
  • Patients with severe calcific degenerative aortic stenosis can be categorized into three clinical groups at the time of diagnosis: those without evidence of congestive heart failure, those with chronic congestive heart failure, and those with acute heart failure requiring hospitalization. (medscape.com)
  • The prevalence of Rheumatic Mitral Stenosis (MS) has significantly changed over the last decades. (biomedcentral.com)
  • A total score of eight or fewer in a patient with symptomatic mitral stenosis (MS) and nonsignificant mitral insufficiency predicts good results and a low complication rate. (biomedcentral.com)
  • Other high-risk cardiac sources of emboli, including left ventricular aneurysm, severe cardiomyopathy, aortic or mitral mechanical heart valve, severe calcific aortic stenosis (valve area (mayo.edu)
  • 75 [4] -100% [5] of valves with calcific degeneration, i.e. calcific aortic stenosis . (librepathology.org)
  • Amyloid deposition in the aortic valve is the precursor lesion of calcific aortic stenosis . (librepathology.org)
  • The presence of a stenosis (narrowing) of the aortic valve. (nih.gov)
  • A narrowing of the right ventricular outflow tract that can occur at the pulmonary valve (valvular stenosis), below the pulmonary valve (infundibular stenosis), or above the pulmonary valve (supravalvar stenosis). (nih.gov)
  • Treatment of stenotic lesions matured in the early 1980s with the advent of balloon valvuloplasty, which has become the predominant therapy for primary pulmonic and mitral stenosis lesions. (medscape.com)
  • Mitral stenosis is characterized by obstruction to LV inflow at the level of mitral valve due to structural abnormality of the mitral valve apparatus. (medscape.com)
  • The most common cause of mitral stenosis is rheumatic fever. (medscape.com)
  • Congenital mitral stenosis can also occur. (medscape.com)
  • Symptoms of mitral stenosis usually manifest during the third or fourth decade of life and nearly half of patients do not recall a history of acute rheumatic fever. (medscape.com)
  • Mitral facies (pinkish-purple patches on the cheeks) indicate chronic severe mitral stenosis leading to reduced cardiac output and vasoconstriction. (medscape.com)
  • Echocardiography is the most specific and sensitive method of diagnosing and quantifying the severity of mitral stenosis. (medscape.com)
  • The goal of medical treatment for mitral stenosis is to reduce recurrence of rheumatic fever, provide prophylaxis for infective endocarditis, reduce symptoms of pulmonary congestion (eg, orthopnea, paroxysmal nocturnal dyspnea), control the ventricular rate if atrial fibrillation is present, and prevent thromboembolic complications. (medscape.com)
  • Read more about mitral stenosis. (medscape.com)
  • 3+) or ≥moderate mitral stenosis. (healthstudiesmn.org)
  • Health Status after Transcatheter vs. Surgical Aortic Valve Replacement in Low-Risk Patients with Aortic Stenosis. (shda.org.au)
Annular5
  • This chronic prolapse occurs mainly in women over the age of 60, and can predispose the patient to mitral annular calcification. (wikipedia.org)
  • Type 1 refers to valve dysfunction with normal leaflet motion, and includes annular dilation and leaflet perforation. (edwards.com)
  • An increasingly prevalent cause in older patients is mitral annular calcification with extension of calcification into the leaflets, causing them to stiffen and not open fully. (msdmanuals.com)
  • What do you think the mitral Dopplers, specifically the mitral annular Dopplers, look like? (medscape.com)
  • Left ventricular outflow tract calcification that would increase the risk of annular rupture or significant paravalvular leak (PVL) post TAVR. (healthstudiesmn.org)
Cardiac16
  • Sudden cardiac death secondary to cardiac arrhythmia is another concern, and continuous monitoring of heart rhythm is helpful in prompt diagnosis of dangerous arrhythmias. (medscape.com)
  • Overview of Cardiac Valvular Disorders Any heart valve can become stenotic or insufficient (also termed regurgitant or incompetent), causing hemodynamic changes long before symptoms. (msdmanuals.com)
  • Rheumatic heart disease (RHD) is a serious cardiac complication of an immune-mediated infectious disease known as a rheumatic fever caused by Streptococcus pyogenes infection in childhood. (biomedcentral.com)
  • The added workload increases the demand for oxygen, and diminished cardiac output causes poor coronary artery perfusion, ischemia of the left ventricle, and left-sided heart failure. (doctorlib.info)
  • Cardiac catheterization, chest X-ray, echocardiography, and electrocardiography are the standard diagnostic tools used to detect valvular heart disease. (doctorlib.info)
  • These T cells were able to recognize several epitopes of cardiac myosin and valve-derived proteins [9, 10]. (fortunejournals.com)
  • Heart valves are situated around the fibrous rings of the cardiac skeleton . (wikipedia.org)
  • Heart valves are the domain of the cardiac surgeon and their bread & butter. (librepathology.org)
  • A cardiac outpouching (CO) is a protrusion in a heart chamber's internal anatomical lining. (dirjournal.org)
  • Efforts to develop and refine percutaneous catheter-based approaches to cardiac valve repair and replacement have advanced rapidly over the past several years. (medscape.com)
  • Heart failure may be considered to be the condition in which an abnormality of cardiac function is responsible for the inability of the heart to pump blood at a rate commensurate with the requirements of the metabolizing tissues, or can do so only at an abnormally elevated filling pressure. (justia.com)
  • In a normal heart that is exposed to long term increased cardiac output requirements, for example, that of an athlete, there is an adaptive process of slight ventricular dilation and muscle myocyte hypertrophy. (justia.com)
  • In this way, the heart fully compensates for the increased cardiac output requirements. (justia.com)
  • Nitrates, arteriolar vasodilators, angiotensin converting enzyme inhibitors have been used to treat heart failure through the reduction of cardiac workload through the reduction of afterload. (justia.com)
  • Patients with cardiac tumors can be asymptomatic or may present with arrhythmia, heart failure, or sudden death. (sts.org)
  • Congenital cardiac tumor is defined as a congenital malformation consisting of growth of abnormal tissue within the heart. (sts.org)
Echocardiography5
Chordae3
Prolapse4
  • An excess of dermatan sulfate in the mitral valve is characteristic of myxomatous degeneration of the leaflets leading to redundancy of valve tissue and ultimately, mitral valve prolapse (into the left atrium) and insufficiency. (wikipedia.org)
  • Type II refers to mitral leaflets with increased mobility, so instances of prolapse or flail. (edwards.com)
  • or prolapse of the valve. (doctorlib.info)
  • Rarely, people with congenital contractural arachnodactyly have heart defects such as an enlargement of the blood vessel that distributes blood from the heart to the rest of the body (aortic root dilatation) or a leak in one of the valves that control blood flow through the heart (mitral valve prolapse). (nih.gov)
Congenital2
Myocardial3
  • Moreover, this scarred myocardial tissue may contain fatty metaplasia and calcification. (dirjournal.org)
  • Acute myocardial infarction (AMI) may be accompanied by hyperglycemia, hepatic insufficiency, and renal failure [ 1 - 4 ]. (hindawi.com)
  • The long-term functional performance may be affected by residual atrioventricular valve insufficiency, ventricular aneurysms, and global myocardial reserve. (sts.org)
Abnormality of the mitral valve1
Tricuspid valve7
  • The four valves in the mammalian heart are two atrioventricular valves separating the upper atria from the lower ventricles - the mitral valve in the left heart, and the tricuspid valve in the right heart. (wikipedia.org)
  • The atrioventricular valves are the mitral valve , and the tricuspid valve , which are situated between the atria and the ventricles , and prevent backflow from the ventricles into the atria during systole . (wikipedia.org)
  • Use of AngioVac for Removal of Tricuspid Valve Vegetation. (qxmd.com)
  • The use is reported of the AngioVac system to resolve a case of persistent bacteremia in the setting of MRSA tricuspid valve infective endocarditis. (qxmd.com)
  • Touching on the TriClip method, which has started to be applied in the treatment of tricuspid valve, and its advantages, Dr. İsmail Ateş said, "As the name suggests, TriClip treatment is a treatment method based on the principle of placing clips (latching) on the valve, which we call the tricuspid valve, instead of the mitral valve, similar to the MitraClip treatment. (medikalteknik.com.tr)
  • After making similar preparations as in the MitraClip treatment, the main treatment goal is to connect the appropriate leaflets of the tricuspid valve, which has three leaflets, with the clip and to reduce the valve leakage. (medikalteknik.com.tr)
  • Penn Medicine cardiovascular imaging specialist Tiffany Chen, MD, discusses the role of imaging in tricuspid valve disease with a focus on pre-procedural imaging. (pennmedicine.org)
Atrioventricular1
Apparatus6
  • The function of the subvalvular apparatus is to keep the valves from prolapsing into the atria when they close. (wikipedia.org)
  • An apparatus for treatment of a failing heart by reducing the wall tension therein. (justia.com)
  • In one embodiment, the apparatus includes a tension member for drawing at least two walls of a heart chamber toward each other. (justia.com)
  • The present invention pertains to the field of apparatus for treatment of a failing heart. (justia.com)
  • In particular, the apparatus of the present invention is directed toward reducing the wall stress in the failing heart. (justia.com)
  • The TAVI treatment method is mostly based on the placement of special apparatus designed as a remote valve stent with a pressure-inflatable balloon into the aortic valve position via the inguinal artery. (medikalteknik.com.tr)
Annulus2
Chronic3
  • The prevalence of Male and patients who were smoking and had multiple comorbidities such as hypertension, dyslipidemia, ischemic heart disease, and chronic kidney disease became increases over time ( p = 0.02, p = 0.02, p = 0.001, p = 0.01, p = 0.02, and p = 0.001, respectively). (biomedcentral.com)
  • With damage to the myocardium or chronic volume overload, however, there are increased requirements put on the contracting myocardium to such a level that this compensated state is never achieved and the heart continues to dilate. (justia.com)
  • Trimetazidine (TMZ) is effective at improving clinical outcomes in chronic heart failure and stable coronary artery disease patients. (hindawi.com)
Leaflet1
  • The fibrosis of the anterior mitral leaflet extends forward along the septum, below the bases of the aortic valves, producing a thickening which extends transversely through the bundle of His. (medlink.com)
Disease26
  • Journal of Heart Valve disease 20.3 (2011): 327. (structuralheart.abbott)
  • By 2005, the total number of cardiovascular disease (CVD) deaths (mainly coronary heart disease, stroke, and rheumatic heart disease) had increased globally to 17.5 million from 14.4 million in 1990. (health.am)
  • Of these, 7.6 million were attributed to coronary heart disease and 5.7 million to stroke. (health.am)
  • Effective treatment for more severe disease consists of balloon commissurotomy, surgical commissurotomy, or valve replacement. (msdmanuals.com)
  • Calcific aortic valve disease occurs on previously normally-functioning valves, either bi- or trileaflet, and less commonly on unicuspid valves. (medscape.com)
  • Aortic sclerosis, which is clinically defined as valve thickening without obstruction to outflow, is the most prevalent valve disease in developed countries, being present in about 25% of patients over age 65 years. (medscape.com)
  • The causes of valvular heart disease are varied and differ for each type of valve disorder. (doctorlib.info)
  • Pathophysiology of valvular heart disease varies according to the valve and the disorder. (doctorlib.info)
  • Rheumatic heart disease (RHD) is the major sequel of rheumatic fever (RF) and leads to valve damage and poor quality of life mainly in children and adolescents. (fortunejournals.com)
  • In Brazil, RF is still present today and is widely prevalent and is the leading cause of valvular heart disease and is thus responsible for significant morbimortality in children and young adults. (fortunejournals.com)
  • Newly ill patients with a history of rheumatic fever, especially rheumatic heart disease who have supporting evidence of a recent GAS infection and who manifest either a single major or several minor criteria: Distinguishing recurrent carditis from preexisting significant RHD may be impossible. (medscape.com)
  • Rheumatic heart disease. (librepathology.org)
  • Any aortic valve disease in which the cause of the disease is a mutation in the SMAD6 gene. (nih.gov)
  • Aortic valve disease-2 (AOVD2) is characterized by bicuspid aortic valve (BAV) and dilation of the ascending aorta. (nih.gov)
  • 2019). For a general phenotypic description and a discussion of genetic heterogeneity of aortic valve disease, see AOVD1 (109730). (nih.gov)
  • The field of percutaneous valve replacement and repair is currently developing at a rapid pace: percutaneous treatment of valvular heart disease is now one of the fastest developing areas of cardiology. (medscape.com)
  • The incidence of valvular heart disease is expected to increase over the next several decades as the "baby boomer" generation passes into advanced decades of life. (medscape.com)
  • Treatment of heart disease-primarily valvular heart disease (as medical treatments for atherosclerosis improve)- is expected to represent one of the main arenas for maintaining good health in this aging population. (medscape.com)
  • With the increasing availability of cardiopulmonary bypass, surgical expertise, and intensive care facilities, valve repair and replacement are widely performed to relieve symptoms and improve prognosis of valvular heart disease, despite the associated morbidity and mortality. (medscape.com)
  • The syndrome of heart failure is a common course for the progression of many forms of heart disease. (justia.com)
  • There are many specific disease processes that can lead to heart failure with a resulting difference in pathophysiology of the failing heart, such as the dilatation of the left ventricular chamber. (justia.com)
  • Fast Five Quiz: Heart Valve Disease - Medscape - Apr 22, 2020. (medscape.com)
  • A sedentary lifestyle and poor cardiorespiratory fitness are independent risk factors for coronary atherosclerotic heart disease [ 8 ]. (hindawi.com)
  • Although entirely preventable, rheumatic heart disease (RHD), a disease of poverty and social disadvantage resulting in high morbidity and mortality, remains an ever-present burden in low-income and middle-income countries (LMICs) and rural, remote, marginalised and disenfranchised populations within high-income countries. (bmj.com)
  • Penn Aorta Center Co-director Nimesh Desai, MD, PhD, outlines the role of the Ross procedure for young patients with aortic valve disease, including how the modern Ross procedure is different, the evolution of Penn's program, and who is a candidate. (pennmedicine.org)
  • Independent predictors of PVE included baseline cirrhosis, renal insufficiency, and pulmonary disease. (shda.org.au)
Transcatheter mitral1
  • The aim of this study was to evaluate the outcomes of transcatheter mitral valve replacement (TMVR) with the Tendyne valve (Abbott Structural) in patients with MR and MAC. (nih.gov)
Dilatation4
  • Type IIIb refers to mitral leaflets that are restricted only in systole, including LV wall motion abnormalities or left ventricular dilatation that result in chordal tethering. (edwards.com)
  • Pathologic diagnosis: Cloudy swelling of heart, with double-sized dilatation. (medlink.com)
  • In a normal heart, the adaptation of muscle hypertrophy (thickening) and ventricular dilatation maintain a fairly constant wall tension for systolic contraction. (justia.com)
  • However, in a failing heart, the ongoing dilatation is greater than the hypertrophy and the result is a rising wall tension requirement for systolic contraction. (justia.com)
Murmur2
  • During that admission a diastolic murmur was noted, and an echocardiogram showed severe aortic insufficiency with a thickened aortic valve. (cdc.gov)
  • Insufficiency (regurgitant flow) - murmur in diastole. (librepathology.org)
Regurgitant1
  • Looking at the density of mitral regurgitant jet I think calling it moderate is fair. (medscape.com)
Patients25
  • In all patients, a valve was implanted with no procedural mortality and successful hospital discharge. (nih.gov)
  • Clinical improvement, measured by New York Heart Association Functional Class, occurred in 11 of 12 patients who were alive at one year. (nih.gov)
  • In patients with MR and severe MAC, TMVR with the Tendyne valve was associated with encouraging acute outcomes, midterm durability, and clinical improvement. (nih.gov)
  • At Abbott, we're helping rebuild better hearts and improve patients' quality of life with an improved benefit-to-risk profile by delivering better therapies, better evidence, and better experiences. (structuralheart.abbott)
  • The study population consists of patients undergone percutaneous balloon mitral valvuloplasty (PBMV) at Emek Medical Center in Israel from January 1990 to May 2019. (biomedcentral.com)
  • The clinical setting (CoNS are significant in patients with prosthetic valves but not in those with native valves. (medscape.com)
  • Rheumatic patients represent 45.7% (5,169 patients) of the valve replacement group and 77.7% (2,556 patients) of the conservative group. (fortunejournals.com)
  • Calcification of the valve and the aorta has been observed, and some patients exhibit coarctation of the aorta (Tan et al. (nih.gov)
  • Transcatheter aortic and pulmonary valve replacement and a variety of mitral valve therapy approaches have been successfully performed in hundreds of patients (see the table below). (medscape.com)
  • Diuretics reduce extra cellular fluid which builds in congestive heart failure patients increasing preload conditions. (justia.com)
  • 60 patients (29,26%) because of respiratory insufficiency, and 21 (10,24%) because of recent postoperative surgery. (biomedcentral.com)
  • Two patients were hospitalized because of multiple trauma and three because of postsurgical respiratory insufficiency. (biomedcentral.com)
  • Lung echography, routinely performed in these patients, revealed areas of atelectasis and or/pleural effusion adjacent to the heart. (biomedcentral.com)
  • Surgical intervention may be indicated depending if patients are symptomatic or significant obstruction to flow and distortion of valve function is present. (sts.org)
  • The use of the drug in patients with heart failure leads to a decrease in preload on the heart muscle after 20 minutes. (farmacy-houses.com)
  • Non-surgical methods, which are hope for advanced heart valve patients where surgery is risky, make you smile. (medikalteknik.com.tr)
  • Stating that non-surgical methods are preferred in the treatment of heart valve diseases in Türkiye as in the whole world, Interventional Cardiologist Assoc. Prof. Dr. İsmail Ateş said, "Non-surgical methods, especially in patients who have difficulty in breathing, help their breathing to improve as well as help them relax their movements. (medikalteknik.com.tr)
  • Noting that surgical intervention can be risky in elderly patients, Dr. Ateş said, "Mitral valve problems are seen in patients with a high age group, and in this case, surgical intervention is risky. (medikalteknik.com.tr)
  • In other words, there is a problem in heart failure and heart valves, but it is not possible to undergo surgery… We can intervene in such surgically rejected patients with the Mitraclip Method. (medikalteknik.com.tr)
  • In this way, the valve is repaired and the patients are discharged after 1 day to return to their normal lives. (medikalteknik.com.tr)
  • After the procedure, the patients' complaints of not being able to breathe due to the heart and breathing irregularity decreased, as well as the growth of the heart stops and the movement capacity of the patients increases. (medikalteknik.com.tr)
  • Aortic valve diseases seen in elderly patients may also be accompanied by insufficiency of vital organs such as lung, kidney and liver. (medikalteknik.com.tr)
  • This paper analyses the incidence of prosthetic valve endocarditis (PVE) in patients with severe AS who received either SAVR or TAVR as part of the PARTNER 1 and PARTNER 2 trials. (shda.org.au)
  • ALIGN-AR was a multicenter, single arm, non-blinded trial with follow-up out to 5 years involving patients with 3-plus or greater AR at high risk for surgical aortic valve replacement . (medscape.com)
  • After Trilogy valve implantation, patients were followed for 1, 6, and 12 months, and annually out to 5 years. (medscape.com)
Left atrial2
  • Chest X-ray shows left atrial and ventricular enlargement, enlarged pulmonary arteries, and mitral valve calcification. (doctorlib.info)
  • TEE provides better-quality images than TTE and is more accurate in assessing the anatomical features of the valve and the presence of left atrial appendage thrombus. (medscape.com)
Respiratory insufficiency1
  • Some forms of SRTD are lethal in the neonatal period due to respiratory insufficiency secondary to a severely restricted thoracic cage, whereas others are compatible with life (summary by Huber and Cormier-Daire, 2012 and Schmidts et al. (beds.ac.uk)
Atrial1
  • The faster heart rate and loss of atrial contraction with onset of atrial fibrillation often lead to sudden worsening of symptoms. (msdmanuals.com)
Anterior and posterior2
Outflow1
Prosthetic1
Endocarditis1
Acute2
  • The prognosis is especially poor in the setting of acute heart failure, for which aortic valve replacement provides the least benefit. (medscape.com)
  • The primary composite safety endpoint included all-cause mortality, any stroke , major vascular complication, major bleeding, a new pacemaker, acute kidney injury , valve dysfunction, or any intervention related to the device. (medscape.com)
Tissue2
  • The inflammatory process that permeates heart lesions is responsible for the recruitment of leukocytes (neutrophils, monocytes and lymphocytes) into the heart tissue, through specific mediators such as chemokines, integrins and selectins that play an important role in the inflammatory process [2, 3]. (fortunejournals.com)
  • Some years ago it was identified the presence of cross reactive antibodies in the surface of valve endothelium [6] and infiltration of T cell clones into the valve tissue [7]. (fortunejournals.com)
Replacement3
  • The SAPIEN M3 system is a fully transseptal mitral valve replacement therapy. (edwards.com)
  • Howard Herrmann, MD, director of interventional cardiology at Penn Medicine, reviews mitral valve replacement vs. repair, current replacement options, and new clinical trial devices. (pennmedicine.org)
  • CA may be present in up to 15% of those with AS and has been associated with higher rates of heart failure, increased mortality, and treatment futility of surgical aortic valve replacement. (shda.org.au)
Aorta4
  • The other two valves are at the entrance to the arteries leaving the heart these are the semilunar valves - the aortic valve at the aorta , and the pulmonary valve at the pulmonary artery . (wikipedia.org)
  • Aortic valve , located at the opening between the left ventricle and the aorta. (wikipedia.org)
  • Calcification, that is, pathological deposition of calcium salts in the aorta. (nih.gov)
  • Penn Aorta Center Co-director Joseph Bavaria, MD, discusses the aortic valve repair program at Penn Medicine. (pennmedicine.org)
Structural1
  • Structural abnormality, fibrosis, or calcification obstructs blood flow from the left atrium to the left ventricle. (doctorlib.info)
Systole1
  • During left ventricular systole, the mitral leaflets do not close normally, and blood is ejected into the left atrium as well as through the aortic valve. (health.am)
Percutaneous1
  • Percutaneous balloon mitral valvuloplasty (PBMV) was first introduced in the early 1980s by Kanji Inoue, a Japanese surgeon. (biomedcentral.com)
Dysfunction3
  • The most prominent late manifestation of RHD is valvular dysfunction, which primarily affects the mitral and aortic valves. (biomedcentral.com)
  • The experiences acquired in surgical technical procedures as well as an overview of pathogenic mechanisms that permeate the autoimmune reactions leading to valve dysfunction are the focus of the present review. (fortunejournals.com)
  • Several oligoclonal T cell expansions were found, indicating that some valve specific proteins were the targets of autoimmune reaction, that culminate into valvar dysfunction [8]. (fortunejournals.com)
Clinical1
  • In late 2021, the National Heart, Lung, and Blood Institute convened a workshop to explore the current state of science, to identify basic science and clinical research priorities to support RHD eradication efforts worldwide. (bmj.com)
Pulmonic valve1
  • This is the continuous-wave Doppler through the pulmonic valve. (medscape.com)
Pulmonary valve2