• fibroblast growth
  • Specifically, the researchers found that in contrast to other dog breeds, all short-legged dog breeds have an extra copy of the gene that codes for a growth-promoting protein called fibroblast growth factor 4 (FGF4). (genome.gov)
  • Researchers with the National Human Genome Research Institute (NHGRI) found that about 20 short-legged dog breeds, including dachshunds, corgis and basset hounds, have two copies of a gene that play a role in production of the protein fibroblast growth factor 4 (FGF4). (bio-medicine.org)
  • Both Indian Hedgehog/Parathyroid Hormone-related Protein (IHh/PtHrP) and fibroblast growth factor (FGF) signaling pathways, important for development of the epiphyseal growth plate, are active in chondroblastoma leading to greater proliferation among the cells in the proliferating/pre-hypertrophic zone (cellular-rich area) versus the hypertrophic/calcifying zone (matrix-rich area). (wikipedia.org)
  • occurs
  • Then calcification of the matrix occurs and osteoprogenitor cells that entered the cavity via the periosteal bud, use the calcified matrix as a scaffold and begin to secrete osteoid, which forms the bone trabecula. (wikipedia.org)
  • The growth in diameter of bones around the diaphysis occurs by deposition of bone beneath the periosteum. (wikipedia.org)
  • Puberty
  • Therefore, an individual mostly stays in the same position in the distribution relative to peers throughout growth, although with some potential for temporary deviation from this track as a result of changes in nutrition, physical activity, or during puberty. (frontiersin.org)
  • Development of osteochondromas take place during skeletal growth between the ages of 13 and 15 and ceases when the growth plate fuses at puberty. (wikipedia.org)
  • known
  • This may be behind the known calcification of growth plates that prevents these breeds' legs from growing, a condition known as disproportional dwarfism, or chondrodysplasia, that is distinctive to these breeds. (bio-medicine.org)
  • The extra carbon dioxide aids photosynthesis, while the more acidic waters increase the concentration of bicarbonate the main ingredient for coccolith plates, known as liths. (thaindian.com)
  • Baumann's angle, also known as the humeral-capitellar angle, is measured on an AP radiograph of the elbow between the long axis of the humerus and the growth plate of the lateral condyle. (wikipedia.org)
  • important
  • The study of these fossils has facilitated important contributions to biostratigraphy, paleontology, evolutionary biology, and plate tectonics. (wikipedia.org)
  • The shells and skeletons produced from calcification have important functions for the physiology and ecology of the organisms that create them. (wikipedia.org)
  • patterns
  • While short connections may be a result of axons pulling on the walls of forming gyri, the axons may adaptively remain short due to mechanical growth patterns. (wikipedia.org)
  • development
  • In this review we describe the regulatory aspects of intrauterine bone development, and then summarize the evidence relating early growth to later fracture risk. (frontiersin.org)
  • Our findings may prove valuable to scientists studying other aspects of human growth and development. (bio-medicine.org)
  • enough
  • The saturation state must be high enough for calcification, and the organism must control the hydrogen ion concentration in the surrounding area. (wikipedia.org)
  • further
  • Heuser and Norris (1929) showed that 11 to 45 minutes of sunshine daily were sufficient to prevent rickets in growing chicks and that no other further improvements in growth were obtained under these conditions by adding cod liver oil (a rich source of vitamin D). (dsm.com)
  • role
  • The only observed role that the cranium may play in gyrification is in flattening of gyri as the brain matures after the cranial plates fuse. (wikipedia.org)
  • network
  • Trabecular marrow is composed of a network of rod- and plate-like elements that make the overall organ lighter and allow room for blood vessels and marrow. (wikipedia.org)