• 2001
  • In addition to her contributions to the study of protein folding, Carol has conducted important work on ribosomes, molecular chaperones and most recently membrane proteins.In 2001, she returned to Cambridge to take up a professorship in the Department of Chemistry, becoming this department's first female professor. (wikipedia.org)
  • nuclear
  • In wild-type cells, macromolecules in the nucleus with the leucine-rich nuclear export signal (NES) can be transported to the cytoplasm by binding to a karyopherin protein called chromosome region maintenance 1 (CRM1)/exportin 1. (wikipedia.org)
  • snRNP70 also known as U1 small nuclear ribonucleoprotein 70 kDa is a protein that in humans is encoded by the SNRNP70 gene. (wikipedia.org)
  • antibodies
  • They are a superfamily of multifunctional conserved proteins, some of which are components of the humoral arm of innate immunity and behave as functional ancestors of antibodies (Abs). (wikipedia.org)
  • CRPs
  • PTX3 (or TSG-14) protein is a cytokine-induced protein that is homologous to CRPs and SAPs, but its function has not yet been determined. (wikipedia.org)
  • detect
  • This uses the method of adding an enzyme to the blood that allows physicians to detect the amount of proteins present. (brighthub.com)
  • Recent applications emphasize the development of increasingly sophisticated techniques to detect additional proteins, genetic material, and markers of nutritional status. (wikipedia.org)
  • glucose
  • This makes the protein structure vulnerable to glycosylation from galactose, glucose, mannose or sialic acid. (brighthub.com)
  • Magnetic resonance imaging shows increase in the size of brain lesions, and CSF abnormalities (white cell count, protein, glucose) increase. (wikipedia.org)
  • blood
  • This changes the pattern in which the protein is structured slightly and can make the blood cells vulnerable to various parasites. (brighthub.com)
  • If a treatment is progressing well, the volume of the proteins in the blood should decline. (brighthub.com)
  • Help
  • The acyl groups are loaded onto the acyl carrier protein (ACP) with the help of the acyltransferase (AT) domain. (wikipedia.org)
  • structure
  • Most scientists see the C-reactive protein structure as a jellyroll structure which forms into a symmetrical unit when it is fully active. (brighthub.com)
  • After a postdoctoral training fellowship at the University of Bristol, she took up a junior position in the mass spectrometry unit at the University of Oxford, where she began analysing protein folding.Her research on the three-dimensional structure of proteins in particular has demonstrated the power of such techniques in studying large molecular compounds. (wikipedia.org)