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  • However, several AAS such as stanozolol, methyltestosterone, oxandrolone, fluoxymesterone and danazol are also used without medical supervision for performance enhancement and muscle building purposes due to their anabolic effects, stimulating protein synthesis and positive nitrogen balance. (medscape.com)
  • Danazol has a complex mechanism of action, and is characterized as a weak androgen and anabolic steroid, a weak progestogen, a weak antigonadotropin, a weak steroidogenesis inhibitor, and a functional antiestrogen. (wikipedia.org)
  • Danazol is described as a possessing high affinity for the androgen receptor (AR), moderate affinity for the progesterone receptor (PR) and glucocorticoid receptor (GR), and poor affinity for the estrogen receptor (ER). (wikipedia.org)
  • As an androgen, danazol is described as weak, being about 200-fold less potent than testosterone in bioassays. (wikipedia.org)
  • Due to their improved side-effect profiles, particularly their lack of masculinizing side effects, danazol has largely been replaced by gonadotropin-releasing hormone analogues (GnRH analogues) in the treatment of endometriosis. (wikipedia.org)
  • Endometriosis minimal mild: Gnrh agonists, danazol, and progestagens do not tolerate needle insertions. (familytreecounseling.com)
  • Danazol, like most other anabolic steroids, has been linked with an increased risk of liver tumors. (wikipedia.org)
  • Women taking danazol should practice effective contraception to prevent pregnancy if sexually active. (wikipedia.org)
  • The activity of danazol at the ER is considered to be minimal, although at very high concentrations the drug can act significantly as an ER agonist. (wikipedia.org)
  • Danazol is contraindicated during pregnancy because it has the potential to virilize female fetuses. (wikipedia.org)
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  • Since danazol is metabolized by the liver, it cannot be used by patients with liver disease, and in patients receiving long-term therapy, liver function must be monitored on a periodic basis. (wikipedia.org)
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  • Some steroid users take more than one dosage a day. (xamuel.com)
  • The usual starting dose for adults is 500 mg 1-2 times a day and the maximum recommended dosage is of 1000 mg three tablets a day. (24x7pharma.com)
  • My advice is to opt life heard of methandienone danazol daily from day 43 due to improved safety in SLE. (usacityfacts.com)
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  • Danazol appears to be useful in the treatment of systemic lupus erythematosus. (wikipedia.org)
  • Although not currently a standard treatment for menorrhagia, danazol demonstrated significant relief in young women with menorrhagia in a study, and, because of a lack of a significant adverse effects, it was proposed as an alternative treatment. (wikipedia.org)
  • Androgenic side effects are of concern, as some women taking danazol may experience unwanted hair growth (hirsutism), acne, irreversible deepening of the voice, or adverse blood lipid profiles. (wikipedia.org)
  • She continued, "Now is the time for women to get into the business. (abhype.com)
  • Although the affinity and efficacy of danazol itself at the PR are relatively low, ethisterone, one of the major metabolites of danazol, is described as a weak progestogen (and has been employed clinically as a progestogen), and this presumably serves to increase the in vivo progestogenic activity of danazol. (wikipedia.org)
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  • Danazol was discovered in 1963 and was introduced for medical use in 1971. (wikipedia.org)
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  • It is taken at a dose of 50 to 400 mg two or three times per day, for a total of 100 to 800 mg per day depending on the indication. (wikipedia.org)
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  • Danazol possesses a complex pharmacology, with multiple mechanisms of action. (wikipedia.org)
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  • Danazol comes in the form of 50, 100, and 200 mg oral capsules. (wikipedia.org)
  • Winsol is an analog of danazol, which promotes extreme fat burning but does not lead to stenosis, dystrophy of the heart muscle, or excessive moisture loss, gp oxan 10 mg oral steroids $59.00 anavar, var. (tayoteaching.com)
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