• Oxidation
  • Mucobromic acid can be synthesized by bromination of furfural via an oxidation/decarboxylation process: C4H4OCHO + 3 Br2 + 3 H2O → C2Br2CHO(CO2H) + CO2 + 8 HBr Mucobromic acid exists as a mixture acyclic and cyclic isomers. (wikipedia.org)
  • driven
  • Roberts and Kimball in 1937 already accounted for the fact that brominations with the maleate ion resulted in cis-addition driven by repulsion between the negatively charged carboxylic acid anions being stronger than halonium ion formation. (wikipedia.org)
  • Although
  • Although acyl bromides are rarely made in comparison with acyl chlorides, they are used as intermediates in Hell-Volhard-Zelinsky halogenation. (wikipedia.org)