• Ketoconazole, USP is a synthetic broad-spectrum antifungal agent. (nih.gov)
  • Ketoconazole is an imidazole broad-spectrum antifungal agent that inhibits synthesis of ergosterol, causing cellular components to leak, resulting in fungal cell death. (medscape.com)
  • Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients. (nih.gov)
  • Background: Ketoconazole was the first broad-spectrum oral antifungal agent available to treat systemic and superficial mycoses. (wntinhibitor.com)
  • Ketoconazole is a broad-spectrum antifungal agent that is in the same category as another azole fungal. (ketomac.co.in)
  • Ketoconazole is an antifungal agent, and it prevents hair from falling when applied to the head and encourages hair growth. (ketomac.co.in)
  • The shampoo contains ketoconazole, which is a broad-spectrum synthetic antifungal agent that helps stop the growth of common yeasts that cause dandruff. (stylishbelles.com)
  • treatment of underlying inflammation and infection is recommended, using a combination of a broad-spectrum topical antifungal agent and a corticosteroid. (aafp.org)
  • Patients with simple chronic paronychia should be treated with a broad-spectrum topical antifungal agent and should be instructed to avoid contact irritants. (aafp.org)
  • Terbinafine is considered a broad-spectrum antifungal agent that can target multiple types of fungi. (camoguys.com)
  • Ketoconazole (Nizoral)--potent oral antimycotic drug. (nih.gov)
  • Ketoconazole, sold under the brand name Nizoral among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. (wikipedia.org)
  • The azole drugs including ketoconazole (Nizoral) , fluconazole (Diflucan) , and itraconazole ( Sporanox) are medicine for yeast infections that have become quite popular in the treatment of vaginal yeast infections . (yeastinfectionadvisor.com)
  • Over the years, Janssen Pharmaceutica has developed and brought to the market over 70 new active substances (NCE), including some prevalent prescription drugs such as Reminyl (Galantamine), Daktarin (Miconazole), Imodium (Loperamide), Motilium (Domperidone), Vermox (Mebendazole), Nizoral (Ketoconazole), Duragesic (Fentanyl), and Risperdal (Risperidone). (brainreference.com)
  • Examples of antifungals include: Griseofulvin (Fulvicin), Ketoconazole (Nizoral), Fluconazole (Diflucan ). (dogproductsguide.com)
  • Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor such as finasteride or dutasteride has been used off label to treat androgenic alopecia. (wikipedia.org)
  • Limited clinical studies suggest ketoconazole shampoo used either alone or in combination with other treatments may be useful in reducing hair loss in some cases. (wikipedia.org)
  • Prominent & Leading Manufacturer from Ahmedabad, we offer terbinafine 250 mg tablets, ketonix shampoo (ketoconazole shampoo), ketoconazole cetrimide (soap), coal tar & salicylic acid shampoo, isotretinoin 20 mg capsules and hydroquinone tretinoin mometasone furoate cream. (schwitzbiotech.net)
  • Ketonix Shampoo is a Ketoconazole Shampoo with Zinc Pyrithione (ZTPO) for Remove Dandruff, Itchy scalp, Seborrheic, Dermatitis. (schwitzbiotech.net)
  • The Ketomac shampoo has had the key ingredient as ketoconazole which ceases the fungal attack on both skin and scalp. (ketomac.co.in)
  • Try a shampoo or facial cleanser with pyrithione zinc or ketoconazole, or a high-concentration green tea cream. (silversneakers.com)
  • Fluconazole is a synthetic triazole antifungal (broad-spectrum bistriazole) that selectively inhibits fungal CYP450 and sterol C-14 alpha-demethylation, which prevents conversion of lanosterol to ergosterol. (medscape.com)
  • Fluconazole is preferred over ketoconazole because of better response rates and less GI and endocrine adverse effects. (medscape.com)
  • The most commonly used antifungal for the treatment of candidoses belong to the azoles family (fluconazole, ketoconazole and itraconazole), and polyenes (nystatin and amphotericin B). Excessive use of these drugs is one of the factors that may favor the development of resistant strains to antifungals [7]. (juniperpublishers.com)
  • Topical ketoconazole is also used as a treatment for dandruff (seborrheic dermatitis of the scalp) and for seborrheic dermatitis on other areas of the body, perhaps acting in these conditions by suppressing levels of the fungus Malassezia furfur on the skin. (wikipedia.org)
  • After pretreatment with omeprazole, a proton pump inhibitor, the bioavailability of a single 200 mg dose of ketoconazole under fasted conditions was decreased to 17% of the bioavailability of ketoconazole administered alone. (nih.gov)
  • It is a narrow-spectrum drug and acts as an inhibitor of DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil. (microbeonline.com)
  • Ketoconazole, a specific inhibitor of CYP3A4, inhibits 78% of the HLM activity toward fipronil at a concentration of 2 microM. (cdc.gov)
  • When ketoconazole cream, 2% was applied dermally to intact or abraded skin of Beagle dogs for 28 consecutive days at a dose of 80 mg, there were no detectable plasma levels using an assay method having a lower detection limit of 2 ng/ml. (nih.gov)
  • Ketoconazole Cream, 2% is contraindicated in persons who have shown hypersensitivity to the active or excipient ingredients of this formulation. (nih.gov)
  • Ketoconazole Cream, 2% is not for opthalmic use. (nih.gov)
  • Ketoconazole Cream, 2% contains sodium sulfite anhydrous, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. (nih.gov)
  • Ketoconazole Cream Is The Best Hormonal Acne Treatment for Adults: In a world where flawless skin is often synonymous with beauty, dealing with acne can be a source of frustration and self-esteem issues for many adults. (drmizanhealth.com)
  • Fortunately, there's a solution that has been gaining popularity in recent years - Ketoconazole Cream. (drmizanhealth.com)
  • In this comprehensive article, we will delve into the world of hormonal acne and explore why Ketoconazole Cream is emerging as the best treatment option for adults dealing with this skin concern. (drmizanhealth.com)
  • What Is Ketoconazole Cream? (drmizanhealth.com)
  • Ketoconazole Cream: It is an antifungal medication commonly used to treat fungal infections on the skin . (drmizanhealth.com)
  • How Does Ketoconazole Cream Work for Hormonal Acne? (drmizanhealth.com)
  • Ketoconazole Cream Work for Acne: Ketoconazole Cream contains an active ingredient that inhibits the production of androgens, the hormones responsible for triggering hormonal acne. (drmizanhealth.com)
  • Safe and Effective: Ketoconazole Cream is generally safe for topical use and has shown significant efficacy in clinical trials. (drmizanhealth.com)
  • Non-Invasive: Unlike some other acne treatments, Ketoconazole Cream is non-invasive and can be easily incorporated into your skincare routine. (drmizanhealth.com)
  • Apply a Thin Layer: Take a small amount of Ketoconazole Cream and apply it evenly to the affected areas. (drmizanhealth.com)
  • While Ketoconazole Cream is generally safe for most individuals, some may experience mild skin irritation, itching, or redness. (drmizanhealth.com)
  • Ketoconazole Cream has emerged as a promising solution for adults dealing with hormonal acne. (drmizanhealth.com)
  • Can Ketoconazole Cream be used for acne prevention? (drmizanhealth.com)
  • Yes, some individuals use Ketoconazole Cream as a preventive measure against hormonal acne. (drmizanhealth.com)
  • How long does it take to see results with Ketoconazole Cream? (drmizanhealth.com)
  • Skineal Cream is a broad spectrum cream with Ketoconazole as the main active ingredient. (healthplusnigeria.com)
  • Ketoconazole, a new orally active broad-spectrum antimycotic, is usually well tolerated. (nih.gov)
  • Orally active, broad-spectrum antimycotic. (drugfuture.com)
  • While ketoconazole blocks the synthesis of the sterol ergosterol in fungi, in humans, at high dosages (>800 mg/day), it potently inhibits the activity of several enzymes necessary for the conversion of cholesterol to steroid hormones such as testosterone and cortisol. (wikipedia.org)
  • Based on these antiandrogen and antiglucocorticoid effects, ketoconazole has been used with some success as a second-line treatment for certain forms of advanced prostate cancer and for the suppression of glucocorticoid synthesis in the treatment of Cushing's syndrome. (wikipedia.org)
  • In vitro studies suggest that ketoconazole impairs the synthesis of ergosterol, which is a vital component of fungal cell membranes. (nih.gov)
  • Ketoconazole interferes in the production of ergosterol- a vital component of the cell membranes of the fungi. (ketomac.co.in)
  • Because ketoconazole tablets have been associated with serious adverse reactions (see WARNINGS section), ketoconazole tablets are not indicated for treatment of onychomycosis, cutaneous dermatophyte infections, or Candida infections. (nih.gov)
  • Ketoconazole has activity against many kinds of fungi that may cause human disease, such as Candida, Histoplasma, Coccidioides, and Blastomyces (although it is not active against Aspergillus), chromomycosis and paracoccidioidomycosis. (wikipedia.org)
  • This alarming growth of multi resistant bacterial infections due to the excessive use of antimicrobials spectrum has been a factor that has favored the dissemination, mainly of microorganisms of the genus Candida , increasing their chances of causing diseases [6]. (juniperpublishers.com)
  • Ketoconazole was patented in 1977 by Belgian pharmaceutical company Janssen, and came into medical use in 1981. (wikipedia.org)
  • In patients with hepatic or renal impairment, the overall pharmacokinetics of ketoconazole was not significantly different when compared with healthy subjects. (nih.gov)
  • The successful treatment of mycotic infections in immunosuppressed renal transplant recipients with ketoconazole. (nih.gov)
  • The illness has a wide spectrum of renal and hepatic involvement and it's subdivided into perinatal (this is the most common), neonatal, infantile and juvenile types on the premise of the age of onset of the clinical presentation and the degree of renal tubular involvement. (ehd.org)
  • An imidazole derivative with a broad spectrum of antimycotic activity. (lookformedical.com)
  • In vitro studies have shown that CYP3A4 is the major enzyme involved in the metabolism of ketoconazole. (nih.gov)
  • Ketoconazole is a broad-spectrum antifungal imidazole used to treat seborrheic dermatitis, fungal skin infections, and vaginal candidiasis. (e-lactancia.org)
  • If your issues are restricted to the scalp, you can consider yourself on the more fortunate end of the seborrheic dermatitis spectrum. (skindrone.com)
  • Serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation has occurred with the use of oral ketoconazole. (nih.gov)
  • The dominant lethal mutation test in male and female mice revealed that single oral doses of ketoconazole as high as 80 mg/kg produced no mutation in any stage of germ cell development. (nih.gov)
  • Growing evidence of serious side effects including endocrine dysregulation, several drug interactions, and death led to the review of oral ketoconazole in 2011. (wntinhibitor.com)
  • Objective: This article chronicles the use of oral ketoconazole from its introduction to its near replacement in medicine. (wntinhibitor.com)
  • Conclusion: Due to its hepatotoxic side effects, oral ketoconazole was withdrawn from the European and Australian markets in 2013. (wntinhibitor.com)
  • Today, oral ketoconazole is only indicated for endemic mycoses, where alternatives are not available or feasible. (wntinhibitor.com)
  • Objectif : Le présent article présente les usages du kétoconazole oral, depuis son arrivée en médecine jusqu'à son remplacement presque total. (wntinhibitor.com)
  • Conclusion : En raison de ses effets secondaires hépatotoxiques, le kétoconazole oral a été retiré du marché en Europe et en Australie en 2013. (wntinhibitor.com)
  • Il reste que le kétoconazole oral est efficace, sûr et largement utilisé pour traiter les mycoses superficielles, notamment en traitement de premier recours du pityriasis versicolor. (wntinhibitor.com)
  • However, the drug was taken off the market in Europe and Australia in 2013 as a result of the risk of serious hepatic side effects.4-6 Similarly, strict restrictions and cautionary advise- ments were added to oral ketoconazole labelling in the US and Canada in 2013. (wntinhibitor.com)
  • Ketoconazole is a weak dibasic agent and thus requires acidity for dissolution and absorption. (nih.gov)
  • Absorption of ketoconazole tablets is reduced in subjects with reduced gastric acidity, such as subjects taking medications known as acid neutralizing medicines (e.g. aluminum hydroxide) and gastric acid secretion suppressors (e.g. (nih.gov)
  • Absorption of ketoconazole under fasted conditions in these subjects is increased when ketoconazole tablets are administered with an acidic beverage (such as non-diet cola). (nih.gov)
  • Following absorption from the gastrointestinal tract, ketoconazole tablets are converted into several inactive metabolites. (nih.gov)
  • After a single topical application to the chest, back and arms of normal volunteers, systemic absorption of ketoconazole was not detected at the 5 ng/ml level in blood over a 72-hour period. (nih.gov)
  • It was speculated that antifungal properties of ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia. (wikipedia.org)
  • Many healthcare providers strongly advocate some broad spectrum antibiotics in case of severe scalp acne particularly when the condition has not responded well to other general treatment. (bestmedicines.pw)
  • Synergistically because growth of the organism occurs, via how to buy vinzam pills South Africa a peripheral catheter with regard to the prescriber if necessary broad spectrum antibiotic. (hybridnutrition.co.za)
  • Oxytetracycline is a broad spectrum antibiotic active against a large number of Gram positive and Gram negative bacteria, certain mycoplasma species, chlamydia, rickettsia and some protozoa. (trusted-tablets.net)
  • Topically administered ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor. (wikipedia.org)
  • Ketoconazole is used orally in dosages of 200 to 400 mg per day in the treatment of superficial and deep fungal infections. (wikipedia.org)
  • These infections are of broad spectrum and affect mainly immunodepressed patients, HIV-positive, cancer patients, patients who make excessive use of antibiotics and those who use immunosupressors therapies as in the case of transplants [8]. (juniperpublishers.com)
  • Sulfadimidine acts usually bactericidal against many Gram-positive and Gram-negative microorganisms like E. coli, Staphylococcus, Streptococcus, Salmonella, Pasteurella and Eimeria spp, so is used as a broad-spectrum antimicrobial to treat or prevent infections caused by susceptible organisms. (trusted-tablets.net)
  • Ketoconazole is an antifungal given by mouth in the form of a tablet, used off label to treat fungal infections in dogs, cats, small mammals, and reptiles. (christianspuller.com)
  • A medicated salve with broad spectrum antimicrobial activity, designed for skin conditions responsive to chlorhexidine and ketoconazole in horses, dogs, and cats. (krmequine.com)
  • Ketoconazole given in a dosage of 400 mg daily or more may inhibit testosterone biosynthesis. (nih.gov)
  • Ketoconazole has been used to prevent the testosterone flare at the initiation of GnRH agonist therapy in men with prostate cancer. (wikipedia.org)
  • Specifically, ketoconazole has been shown to inhibit cholesterol side-chain cleavage enzyme, which converts cholesterol to pregnenolone, 17α-hydroxylase and 17,20-lyase, which convert pregnenolone into androgens, and 11β-hydroxylase, which converts 11-deoxycortisol to cortisol. (wikipedia.org)
  • In any case, the risk of hepatotoxicity with ketoconazole limits its use in all of these indications, especially in those that are benign such as hirsutism. (wikipedia.org)
  • Ketoconazole can cause elevated plasma concentrations of these drugs and may prolong QT intervals, sometimes resulting in life-threatening ventricular dysrhythmias such as torsades de pointes. (nih.gov)
  • these are broad-spectrum and fungicide drugs. (microbeonline.com)
  • Meanwhile, topical ketoconazole is effective, safe, and widely prescribed for superficial mycoses, particularly as the first-line treatment for tinea versicolor. (wntinhibitor.com)
  • It has antibacterial activity against a broad spectrum of Gram-negative and Gram-positive bacteria. (trusted-tablets.net)
  • Keto WELL topical spray is designed for topical use on common skin conditions responsive to Chlorhexidine and Ketoconazole. (nih.gov)
  • Ketoconazole tablets should be used only when other effective antifungal therapy is not available or tolerated and the potential benefits are considered to outweigh the potential risks. (nih.gov)
  • Limited pharmacokinetic data are available on the use of ketoconazole tablets in the pediatric population. (nih.gov)
  • Measurable ketoconazole plasma concentrations have been observed in pre-term infants (single or daily doses of 3 to 10 mg/kg) and in pediatric patients 5 months of age and older (daily doses of 3 to 13 mg/kg) when the drug was administered as a suspension, tablet or crushed tablet. (nih.gov)
  • Ketoconazole has additionally been used, in lower dosages, to treat hirsutism and, in combination with a GnRH analogue, male-limited precocious puberty. (wikipedia.org)
  • It contains a broad spectrum of ingredients with anti-fungal, anti-inflammatory and anti-microbial activity. (neofollics.com)
  • Treatment of blastomycosis and histoplasmosis with ketoconazole. (nih.gov)
  • The side effects of ketoconazole are sometimes harnessed in the treatment of non-fungal conditions. (wikipedia.org)
  • Customized treatments hair loss treatments formula available for dermatologists & hair surgeons for broad spectrum hair loss treatments to cover chemical & pregnancy induced hair loss, and hormone related hair loss treatment. (thezenweb.com)
  • Physicians preferred choice for Men's treatment are the formula with 0.1% finasteride , Minoxidil 5% solution with S.Equol and ketoconazole. (thezenweb.com)
  • Ketoconazole, USP is a white or almost white powder that is soluble in acids. (nih.gov)
  • adoxa However, the Raman spectra immunosuppressant and X-ray powder diffraction pattern. (marketypik.pl)
  • And concurrent illnesses, and reducing waste in primary health, services and promotions that appeal azithromycin in South Africa price to a broad patient. (hybridnutrition.co.za)
  • These compounds play an important role in medicinal fields because of their wide spectrum of biological activities. (scirp.org)