• The peripheral axons of auditory nerve fibers form synaptic connections with the hair cells of the cochlea via ribbon synapses using the neurotransmitter glutamate. (wikipedia.org)
  • The central axons form synaptic connections with cells in the cochlear nucleus of the brainstem. (wikipedia.org)
  • These central axons exit the cochlea at its base and form a nerve trunk, which, in humans, is approximately one inch long. (wikipedia.org)
  • In mammals, the axons from each cochlear nerve terminate in the cochlear nuclear complex that is ipsilaterally located in the medulla of the brainstem. (wikipedia.org)
  • In cross section, the spinal cord is divided into an H-shaped area of gray matter (consisting of synapsing neuronal cell bodies) and a surrounding area of white matter (consisting of ascending and descending tracts of myelinated axons). (lecturio.com)
  • Immunoelectron microscopy revealed excitatory synaptic connections between regenerating host axons and graft-derived neurons at C1 as well as between graft axons and DCN neurons in the brainstem. (jneurosci.org)
  • Gray matter is made up of neuronal cell bodies, while white matter primarily consists of myelinated axons. (technologynetworks.com)
  • The myelin sheath is where the nerve axons serve as an electrical insulator that speeds up nerve impulses to muscles and other effectors. (bartleby.com)
  • Multiple Sclerosis (MS) is a type of autoimmune disease in which the myelin sheath that covers axons and speeds up the transmission of nerve impulse in the brain is damaged or destroyed. (bartleby.com)
  • One of the critical things that happens during the development of the embryonic brain is the growth of millions of nerve fibers or "axons" to form connections among all the neurons in the developing brain. (blogspot.com)
  • Describe the variety of afferent fibers (axons) used by the subsystems. (powershow.com)
  • The neuronal cell bodies of a nerve's axons are in the brain, the spinal cord, or ganglia, but the nerves run only in the peripheral nervous system. (unboundmedicine.com)
  • Nerves with axons that conduct electrochemical impulses toward the central nervous system (CNS) are afferent, nerves with axons that conduct impulses away from the CNS are efferent, and nerves with both afferent and efferent axons are mixed. (unboundmedicine.com)
  • The components of the eighth cranial nerve (CN VIII) carrying axons that convey information regarding sound and balance between the spiral ganglion in the inner ear and the cochlear nuclei in the brainstem. (unboundmedicine.com)
  • The axons of the lower motor neurons are the efferent fibers of the spinal nerves. (msdmanuals.com)
  • The axons of these GVE fibers travel through the anterior horn and exit the cord in the anterior root before entering the spinal nerve. (blogspot.com)
  • The axons of the A delta are thinly myelinated with a faster conduction speed of 5-15 m/s in contrast to the unmyelinated C fibers with a conduction speed of 1-2 m/s. (mhmedical.com)
  • With minor exceptions, nociceptive fibers have finely myelinated or unmyelinated axons. (nationalacademies.org)
  • The most extensively studied nociceptors are the ones that have myelinated axons and respond only to intense mechanical or mechanical and thermal stimuli and the so-called polymodal nociceptors, which have unmyelinated axons and respond to mechanical, thermal, and chemical stimuli. (nationalacademies.org)
  • Both the peripheral process and the axon are myelinated. (wikipedia.org)
  • Each type I axon innervates only a single inner hair cell, but each inner hair cell is innervated by up to 30 such nerve fibers, depending on species and location within the cochlea. (wikipedia.org)
  • An exam- ple of a slowly adapting position detector is a Type I Iggo corpuscle, featured by a myelinated axon ter- minating at the base of a small dome-like elevation in the skin (Merkel cells). (cdc.gov)
  • Proximally, the outer core is penetrated by a canal which contains a single myelinated pre- terminal axon (7-11 ,um across), continuous with a long naked axon terminal deep in the center of the corpuscle. (cdc.gov)
  • This is not surprising given the strong evidence for interaction between myelin and axon gene expression in development and after experimental nerve lesions. (medscape.com)
  • Degeneration in the nervous system, retrograde changes affect neuronal modulation, transport and connectivity, anterograde changes and gliotic response can impair/impede outgrowth and/or reduce the diameter of the regenerating axon, lowering conduction velocity in the fiber. (evokedpotential.com)
  • 36. What is a myelinated axon? (fsu.edu)
  • A nerve impulse is the flow of electrical current along the Axon membrane. (freezingblue.com)
  • The facial nerve is composed of approximately 10,000 neurons, 7,000 of which are myelinated and innervate the nerves of facial expression. (medscape.com)
  • In 1987, Jenny and Saper performed an extensive study of the proximal facial nerve organizations in a primate model and found evidence that in monkeys, upper facial movement is relatively preserved in upper motor neuron injury, because these motor neurons receive relatively little direct cortical input. (medscape.com)
  • Each part contains groups of nuclei that function as relay centers for sensory Sensory Neurons which conduct nerve impulses to the central nervous system. (lecturio.com)
  • The proximal axonal processes of the first-order neurons in these ganglia reach the brainstem nuclei via their respective cranial nerves, where they synapse with second-order neurons in brainstem nuclei. (brainkart.com)
  • Pain fibers may ascend or descend one to three spinal cord segments in Lissauer's tract before synapsing with second-order neurons in the gray matter of the ipsilateral dorsal horn. (brainkart.com)
  • VGLUT3-transient neurons are large- or medium-diameter myelinated mechanoreceptors that form the Merkel cell-neurite complex. (jneurosci.org)
  • VGLUT3-persistent neurons are small-diameter unmyelinated neurons that are further divided into two subtypes: (1) tyrosine hydroxylase (TH)-positive C-LTMRs that form the longitudinal lanceolate endings around hairs, and (2) TH-negative neurons that form epidermal-free nerve endings. (jneurosci.org)
  • The deficits observed with unilateral ablation of the corticobulbar fibers reflect the fact that upper facial motor neurons do not receive significant cortical innervations and that lower facial motor neurons contralateral to the lesion, which have functional loss, are dependent on direct contralateral cortical innervation, with the remaining ipsilateral cortical projections being insufficient to drive them. (medscape.com)
  • The anterior (ventral) horns of the "H" contain lower motor neurons, which receive impulses from the motor cortex via the descending corticospinal tracts and, at the local level, from internuncial neurons and afferent fibers from muscle spindles. (msdmanuals.com)
  • The gray matter also contains many internuncial neurons that carry motor, sensory, or reflex impulses from dorsal to ventral nerve roots, from one side of the cord to the other, or from one level of the cord to another. (msdmanuals.com)
  • While the general somatic efferent (GSE) fibers (alpha and gamma motor neurons of the anterior horn) continue in the spinal nerve trunks to innervate skeletal muscle fibers and muscle spindles, almost all of the GVE fibers leave the spinal nerve trunks to enter sympathetic ganglia via a thin arm, the white ramus (Figs-1, 2, and 3). (blogspot.com)
  • The nuclei contain large motor neurons and myelinated fibers of the hypoglossal nerve, innervating the intrinsic and extrinsic tongue muscles , excluding palatoglossus 1,2 which is innervated by the vagus nerve . (radiopaedia.org)
  • Animals with pain after chronic constriction injury of the infraorbital nerve (CCI-Pain) displayed higher spontaneous and evoked activity in PB neurons, and a dramatic increase in after-discharges-responses that far outlast the stimulus-compared to controls. (iasp-pain.org)
  • The former courses ventrally into the first branchial arch and terminates near a branch of the trigeminal nerve that eventually becomes the lingual nerve. (medscape.com)
  • The gasserian ganglion contains the cell bodies of sensory fibers in the oph-thalmic, maxillary, and mandibular divisions of the trigeminal nerve. (brainkart.com)
  • Introduction: Trigeminal neuralgia (TN) is defined as sudden, usually unilateral, severe and brief pain episodes within the distribution of one or more branches of the trigeminal nerve. (bvsalud.org)
  • Literature review: One of the proposed etiologies for this condition is a localcircumscribed demyelination of the trigeminal nerve resulting in neuronal hyperexcitability and generation of ephaptic coupling, which would be responsible for the pain paroxysms. (bvsalud.org)
  • The pathophysiology is unclear, but trigeminal neuralgia seems to be the consequence of vascular compression of the trigeminal nerve near the brain stem. (bvsalud.org)
  • Trigeminal neuralgia is def ined by the International Association for the Study of Pain (IASP) as a "sudden, usually unilateral, severe and brief pain episodes occurring in one the distribution of one or more branches of the trigeminal nerve" 32,46 and characterized by severe, acute, electric shock-like piercing pain, followed by refractory period 3,24 . (bvsalud.org)
  • Pain episodes are normally triggered by stimulation of specific areas, so-called trigger points or zones, localized in the area innervated by trigeminal nerve 26 . (bvsalud.org)
  • The corona radiata is a crucial group of nerves because of its function in sending out and getting messages between regions in the brain.1 The nerve cells of the corona radiata are described as both afferent and efferent. (healthymagazine.net)
  • The corona radiata is made up of both afferent and efferent fibers that connect the cortex and the brain stem. (healthymagazine.net)
  • In either case the nerve fibers of the ANS are motor only, and represent the general visceral efferent (GVE) fibers of the cranial and spinal nerves. (blogspot.com)
  • Ear anatomy Cochlear nucleus innervated by a branching auditory nerve fibre Terminal nuclei of the vestibular nerve, with their upper connections. (wikipedia.org)
  • Additionally, the medial longitudinal fasciculus is responsible for transporting fibers that originate in the vestibular nuclei and are destined for the oculomotor, trochlear, and interstitial nuclei of Cajal. (healthncare.info)
  • The hypoglossal nuclei , exist as paired nuclei within the medulla oblongata that provide motor innervation to the intrinsic and extrinsic muscles of the tongue (excluding palatoglossus) via the hypoglossal nerve . (radiopaedia.org)
  • Small myelinated Aδ fibers and unmyelinated C fibers are responsible for the transmission of painful stimuli to the spinal cord where these afferent primary fibers terminate in the dorsal horn. (healthbeautytips.in)
  • A delta fibers respond to mechanical and thermal stimuli. (mhmedical.com)
  • and those of the vagal nerve are located in the jugular ganglion (somatic) and the ganglion nodosum (visceral). (brainkart.com)
  • What are two sensations regulated by somatic afferent fibers? (flashcardmachine.com)
  • A somatic motor nerve originating in the abducens nucleus in the pons. (unboundmedicine.com)
  • These three send gray rami to all eight cervical spinal nerves. (blogspot.com)
  • Consequently, all 31 pairs of spinal nerves are in contact with the sympathetic chain and carry fibers of the sympathetic system. (blogspot.com)
  • This is an important feature, enabling those effector organs which are innervated only by spinal nerves (cutaneous and skeletal muscle blood vessels, sweat glands, and pilomotor smooth muscle) to receive sympathetic input. (blogspot.com)
  • Subtle decreases in grey matter volume, mainly localised in frontal areas, were found, but extensive white matter atrophy was observed, particularly in frontal areas, but also involving multiple additional subcortical areas, the cerebellar white matter and the dorsal brainstem from the midbrain to the medulla oblongata. (nih.gov)
  • Discharges from the facial motor area are carried through fascicles of the corticobulbar tract to the internal capsule, then through the upper midbrain to the lower brainstem, where they synapse in the pontine facial nerve nucleus. (medscape.com)
  • The MLF is a pair of highly specialized nerve fibers that are highly myelinated and run in a craniocaudal direction just ventral to the cerebral aqueduct and the fourth ventricle in the tegmentum of the midbrain and the dorsal pons. (healthncare.info)
  • These nerve fibers are located in the tegmentum of the midbrain and the dorsal pons. (healthncare.info)
  • Certain clinical signs are manifested in a patient when a lesion affects the heavily myelinated tracts of the MLF. (healthncare.info)
  • The white matter at the cord's periphery contains ascending and descending tracts of myelinated sensory and motor nerve fibers. (msdmanuals.com)
  • The Medial Longitudinal Fasciculus is a fiber tract located ventrolaterally to the oculomotor nucleus that connects the trochlear nucleus, oculomotor nucleus, and abducens nucleus. (healthncare.info)
  • A group of crossed fibers with ascending and descending fibers is known as the medial longitudinal fasciculus and is located in the brainstem. (healthncare.info)
  • As afferent fibers enter the spinal cord, they segre-gate according to size, with large, myelinated fibers becoming medial, and small, unmyelinated fibers becoming lateral. (brainkart.com)
  • The nerve fibers which comprise the sympathetic system originate in the inter-mediolateral horn (lamina VII) of the gray matter in all twelve thoracic and the first two lumbar segments of the spinal cord. (blogspot.com)
  • Since various bands of fibers (fibers of the fasciculus retroflexus, rootlets of the oculomotor nerve, and fibers of the superior cerebellar peduncle) pass through the red nucleus (3, 4) , it has been proposed that these myelinated fiber bundles constitute the lamellae (1) . (ajnr.org)
  • They have relatively large diameters, are bipolar, and are myelinated. (wikipedia.org)
  • To innervate these muscles, the facial nerve courses across the region that eventually becomes the middle ear. (medscape.com)
  • the inferior alveolar nerves innervate the lower teeth and gingivae. (unboundmedicine.com)
  • The anterior superior alveolar nerves, branches of the infraorbital nerve (from CN V2), run in canals in the anterior wall of the maxillary sinus and innervate the upper incisors, canines, premolars, and often part of the first molar. (unboundmedicine.com)
  • The posterior superior alveolar nerves (also from CN V2) innervate the rest of the upper molars. (unboundmedicine.com)
  • Autonomic nerve fibers innervate cardiac muscle, smooth muscle, and glands. (blogspot.com)
  • The auricular branch of the vagus nerve is a sensory nerve emerging from the superior ganglion of the vagus nerve, joined by branches from the glossopharyngeal (CN IX) and facial nerves, and innervating the lower part of the tympanic membrane and the floor of the external auditory canal. (unboundmedicine.com)
  • Specifically, the nerves of the corona radiata bring details between the brain cells of the cerebral cortex & the brain cells in the brain stem. (healthymagazine.net)
  • The brain stem & the cerebral cortex both are required in feeling and motor function, & the corona radiata connects both motor and sensory nerve paths in between these structures. (healthymagazine.net)
  • Might pain be experienced in the brainstem rather than in the cerebral cortex? (researchgate.net)
  • This travels in parallel with the vestibular nerves through the internal auditory canal, through which it connects to the brainstem. (wikipedia.org)
  • The superior cervical ganglion sends to the first four cervical nerves, the smaller middle cervical ganglion supplies the next two, and the large inferior cervical ganglion projects a gray ramus to the seventh and eighth cervical nerves. (blogspot.com)
  • GBS is a group of autoimmune diseases with acute/subacute evolution characterized by progressive and ascending motor deficit in the limbs, often with sensory, cranial nerve involvement ( 4 , 6 ). (spandidos-publications.com)
  • 4 Pathological findings from muscle and nerve biopsies, reported by Larbrisseau et al 5 , revealed evidence of chronic denervation with angular fibers and type grouping, suggesting an axonal neuropathy and a major primary defect at the level of peripheral nerve in HMSN/ACC. (nature.com)
  • Now a large and ever increasing number of genetic subtypes has been described, and major advances in molecular and cellular biology have clarified the understanding of the role of different proteins in the physiology of peripheral nerve conduction in health and in disease. (medscape.com)
  • A muscle or gland innervated by autonomic fibers is called an effector organ. (blogspot.com)
  • If the autonomic nerve fibers to an effector organ are cut, the organ may continue to function, but will lack the capability of adjusting to changing conditions. (blogspot.com)
  • If the autonomic nerve fibers to the heart are cut, the heart will continue to beat and pump blood normally, but its ability to increase cardiac output under stress will be seriously limited. (blogspot.com)
  • Previous neuropathological observations in HMSN/ACC patients have included the presence of small oval vacuoles in the brain white matter, signs of axonal swelling and depletion of large myelinated fibers in nerves. (nature.com)
  • The corona radiata is a bunch of nerve fibers situated in the brain. (healthymagazine.net)
  • Three thousand of the nerve fibers are somatosensory and secretomotor and make up the nervus intermedius. (medscape.com)
  • The neural elements of somatosensory receptors in the hands and feet represent the distal extreme of long afferent fibers, and thus, are par- ticularly vulnerable in the distal axonopathies. (cdc.gov)
  • The facial nerve , or cranial nerve (CN) VII, is the nerve of facial expression. (medscape.com)
  • The pathways of the facial nerve are variable, and knowledge of the key intratemporal and extratemporal landmarks is essential for accurate physical diagnosis and safe and effective surgical intervention in the head and neck. (medscape.com)
  • The course of the facial nerve and its central connections can be roughly divided into the segments listed in Table 1, below. (medscape.com)
  • By the eleventh week, the facial nerve has arborized extensively. (medscape.com)
  • [ 1 , 2 ] The reader is referred to these references for a more detailed description of the supranuclear and nuclear organization of the facial nerve . (medscape.com)
  • The pontine facial nerve nucleus is divided into an upper and a lower half, bilaterally. (medscape.com)
  • The hypoglossal nucleus receives corticonuclear fibers , from the precentral gyrus and adjoining areas from both the ipsilateral and contralateral cerebral hemispheres, however primarily from the latter 1 . (radiopaedia.org)
  • Some unmyelinated afferent (C) fibers have been shown to enter the spinal cord via the ventral nerve (motor) root, accounting for obser-vations that some patients continue to feel pain even after transection of the dorsal nerve root (rhizotomy) and report pain following ventral root stimulation. (brainkart.com)
  • When the trochlear nerve is damaged, the superior oblique muscle on the affected side weakens, leading to internal rotation of the thigh and hyperextension of the affected leg. (healthncare.info)
  • Nerve conduction velocities are severely decreased (sometimes less than 10 m/s), and sural nerve biopsy shows severe loss of myelinated fibers (summary by Baets et al. (nih.gov)
  • In the late 1960s, neurophysiologic testing allowed the classification of CMT into 2 groups, one with slow nerve conduction velocities and histologic features of a hypertrophic demyelinating neuropathy (hereditary motor and sensory neuropathy type 1 or CMT1) and another with relatively normal velocities and axonal and neuronal degeneration (hereditary motor and sensory neuropathy type 2 or CMT2). (medscape.com)
  • Clinical opinion discourages surgical resection of nerves proximal to the original injury site for fear of resurgence of ectopia and exacerbated pain. (researchgate.net)
  • The abducens nucleus is connected to the contralateral oculomotor nucleus by the fasciculus fibers, which enables horizontal conjugate lateral gaze as well as saccadic eye movements. (healthncare.info)