Brain networks human connectome anatomical connectome. Medical search. Frequent questions

Results: The two key components of structural connectome are a node (a cortical region obtained with high-resolution anatomical imaging) and an edge (structural association between cortical regions, defined with tractography). (johnshopkins.edu)
Biological substrates of brain development such as cortical gyration and myelination challenge the acquisition, reconstruction, and analysis of structural connectome in children and require specific considerations compared to adults. (johnshopkins.edu)
The proposed method jointly analyzes whole brain dMRI and fMRI data, allowing the estimation of complete function-specific structural networks instead of interactively investigating the connectivity of individual cortical/sub-cortical areas. (umn.edu)
The complex mosaic of changes in brain morphology and functional organization that have shaped the mammalian cortex during evolution, complicates attempts to chart cortical differences across species. (harvard.edu)
Collating and combining data across multiple studies on the cortical cytoarchitecture of the macaque cortex with information on macroscale anatomical wiring derived from tract tracing studies, this study focuses on examining the interplay between macroscale organization of the macaque connectome and microscale cortical neuronal architecture. (amsterdamumc.org)
Our findings show that both macroscale degree as well as the topological role in the overall network are related to the level of neuronal complexity of cortical regions at the microscale, showing (among several effects) a positive overall association between macroscale degree and metrics of microscale pyramidal complexity. (amsterdamumc.org)
Here we show that compensatory arm usage in individuals born without a hand (one-handers) reflects functional connectivity of spontaneous brain activity in the cortical hand region. (elifesciences.org)
Neuron geometry underlies universal network features in cortical microcircuits. (epfl.ch)
A densely-connected lateral prefrontal and posterior parietal cortical network orchestrates responses to novel cognitive tasks using flexible hubs . (biosourcesoftware.com)
These findings demonstrate for the first time that resting state fMRI is sensitive to structural connections between cortical layers, specifically in thalamocortical and cortico-cortical networks. (auburn.edu)

The effects of connection reconstruction method on the interregional connectivity of brain networks via diffusion tractography. (crossref.org)
Hence, functional connectivity (R-fMRI) and anatomical connectivity (tractography) are complementary yet related measures that together provide a powerful approach to analyzing brain circuitry. (humanconnectome.org)
Using MRI data, for each participant, we constructed whole-brain interregional connectivity matrices by deterministic tractography and calculated the graph theoretical network measures, including the characteristic path length, global clustering coefficient, small-worldness, and betweenness centrality (BET) in 83 brain regions from the Desikan-Killiany atlas with subcortical segmentation using FreeSurfer. (nature.com)
Subsequently, to refine the data from fMRI and obtain structural data, diffusion tensor imaging (DTI) and tractography techniques are used to construct higher-resolution images that precisely show the mapping of neural tracts through the brain (Sughrue, 2022). (simplyneuroscience.org)
MRI has proven to be a valuable tool for examining connectivity both in terms of the coordinated activities of neural networks (using BOLD-based fMRI data collected during rest and during tasks) and in terms of the structural anatomy of white matter pathways of the brain (using Diffusion Tensor Imaging (DTI), Diffusion Spectrum Imaging (DSI) and Tractography to analyze and visualize the resulting data). (martinos.org)

Generating high-resolution anatomical maps at the scales necessary to characterize mammalian brain connectomes and projectomes will both press the boundaries of current computational capabilities and drive innovations in data science including artificial intelligence and machine learning. (nih.gov)
As seen, the insect brain may be smaller and simpler than a mammalian brain, but it still exhibits complex functions like learning, memory, and decision-making. (whatsthatbug.com)
Macroscale connectivity of the mammalian brain has been shown to display several characteristics of an efficient communication network architecture. (amsterdamumc.org)
The publicly available dataset resulting from approximately a thousand new experiments represents the most detailed map of connections in a mammalian brain to date, tracing neural wiring within and between the thalamus and cortex, the outermost shell of the mammalian brain that is responsible for higher level functions like memory, decision making, and understanding the world around us. (alleninstitute.org)
To get a more detailed view of how the mammalian brain is wired, the researchers studied connections between specific classes of neurons covering two major parts of the brain, the cortex and thalamus. (alleninstitute.org)
Nobody has yet mapped a complete synapse-by-synapse connectome of a mammalian brain, but capturing the connections made by different classes of cells allowed the researchers to uncover new information about how the wiring diagram is organized. (alleninstitute.org)
The team has acquired, analyzed, and freely shared a vast amount of high-quality anatomical connectivity data, thereby providing the most extensive 'meso-connectome' description to date for the wiring of any mammalian brain. (alleninstitute.org)

Generative models of the human connectome. (indiana.edu)
Using resting fMRI data, we investigated the assumptions undergirding current models of the human connectome. (stanford.edu)

Though smaller and simpler than human brains, fly brains reveal fascinating neural networks that contribute to their complex cognitive abilities. (whatsthatbug.com)
The differentiable program that we envision occupies a niche midway between traditional pipelines and end-to-end neural networks, combining the glass-box tractability and domain knowledge of the former with the amenability to optimisation of the latter. (stanford.edu)
Multiple large-scale neural networks orchestrate a wide range of cognitive processes. (researchgate.net)
Summary: A new study reveals how morphological changes in the brain help to shape its neural networks. (neurosciencenews.com)
New research from Newcastle University, UK, and published today in the academic journal Trends in Cognitive Science , shows for the first time how morphological changes in the brain help shape its neural networks - the human connectome. (neurosciencenews.com)

Insects have brains with neurons connected in intricate networks. (whatsthatbug.com)
Additionally, the connectome of an insect brain was mapped, revealing intricate networks of interconnected neurons in the Drosophila larva. (whatsthatbug.com)
Its compact yet complex brain structure offers insights into the function of neurons and brain organization. (whatsthatbug.com)
This groundbreaking connectome consists of 3,016 neurons and 548,000 connections between them. (whatsthatbug.com)
My research program focuses on understanding the general organizational and functional principles of connectomes - network maps of the connectivity among neurons, neuronal populations, and large-scale brain areas. (indiana.edu)
Exactly when and where individual neurons develop is as important to our understanding of brain diseases as the underlying genetics, experts have shown. (neurosciencenews.com)
Brain neurons tend to grow in straight lines, searching out other neurons to form a connection with. (neurosciencenews.com)
These networks interact through feedback loops and transiently organized aggregates of neurons, all mediated by rhythmic, oscillatory electrical discharges that ultimately produce the EEG. (biosourcesoftware.com)
The mouse brain has approximately 85 million neurons that make roughly 100 billion connections, or synapses. (alleninstitute.org)
Simply put neurons in the brain talk to other neurons via electrochemical signaling, creating lines of communication that eventually intersect with other "conversations", or communication pathways, to build the elaborate structure of connections that facilitate every unconscious and conscious demand of the human experience. (simplyneuroscience.org)

Even contemporary definitions of the connectome rest upon the formulation of a neuronal theory that has been proposed over a hundred years ago. (nih.gov)
The model simulates electrical activity across neuronal populations of a number of brain regions and converts that activity into fMRI and MEG time-series. (modeldb.science)
Together, we report on cross-scale observations that jointly suggest that a region's microscale neuronal architecture is tuned to its role in the global brain network. (amsterdamumc.org)
The emergence and continual refinement of large-scale brain networks, connecting neuronal populations across anatomical distance, allows for increasing functional integration and specialisation. (ox.ac.uk)

Gordon and colleagues (2023), using precision fMRI from seven participants and fMRI datasets from the Adolescent Brain Cognitive Development Study, Human Connectome Project, and UK Biobank from 50,000 individuals, found three interconnected primary motor cortex (M1) regions that participate in the integrated movement of multiple body parts. (biosourcesoftware.com)
these areas include specific cortex regions, the cerebellum, and the retina (Connectome Coordination Facility, 2023). (simplyneuroscience.org)
The HCP is using a connectomics approach (building neural connective maps using technology) in assessing the structural and functional differences of brains in healthy, diseased, and life-span individuals, which includes infants, adolescents, and aging populations (Connectome Coordination Facility, 2023). (simplyneuroscience.org)

Historically, neuroscience has focused on studying the individual components of the nervous system-cells, lobes, tissues, brain chemistry, and anatomical structures-but only recently have scientists endeavored to produce a body of knowledge denoting the one feature of the brain that may just explain its unique capacities: neural connectivity (Betzel, 2022). (simplyneuroscience.org)
The result of these technologies combined is a colorful and strikingly clear image of nerve tracts and their connections with each other as they navigate different brain areas (Doyen, 2022). (simplyneuroscience.org)

The spatial patterns of correlation can also be used to create extensive systems/network level descriptions of functional interactions across brain regions that can be compared to anatomical connectivity descriptions, and task-evoked functional activations. (humanconnectome.org)
The topology of structural brain networks and its role in shaping patterns of functional connectivity. (indiana.edu)
Structural, geometric and genetic factors predict interregional brain connectivity patterns probed by electrocorticography. (indiana.edu)
Hierarchical complexity is an emerging paradigm of complex network topology based on the observation that complex systems are composed of hierarchies within which the roles of hierarchically equivalent nodes display highly variable connectivity patterns. (hdruk.org)
This provides a new key description of brain structure, revealing a rich diversity of connectivity patterns within hierarchically equivalent nodes. (hdruk.org)
We then show that such diversity of connectivity patterns aligns with the diversity of functional roles played out across the brain, demonstrating that hierarchical complexity can characterise functional diversity strictly from the network topology. (hdruk.org)
This motivates the idea that the brain can be parcellated into functionally coherent regions based on anatomical connectivity patterns that capture how different areas are interconnected. (ru.nl)
The second question which naturally arises, is which differences in neural activation patterns will emerge within the brain's structural network when simulating different conditions (i.e. (frontiersin.org)
In contrast to correlation-based or independent component analysis (ICA) functional connectivity mapping, detailed anatomical connectivity patterns are revealed for each functional module. (umn.edu)
Yet, considerable variability exists in the connectivity patterns between different brain areas, potentially producing reliable group differences. (researchgate.net)
All of our analytical studies enjoy me to predict brand new directionality patterns during the standard model sites and mind networking sites around the more says out-of consciousness. (dazrozpharma.com)
However, this view emerges from investigating static FC overlooking the age, disease phenotype and their interaction in the whole brain transient connectivity patterns. (biorxiv.org)

From experiments in the macaque monkey, R-fMRI correlations often overlap with known anatomical pathways, but they sometimes involve regions that are not directly connected. (humanconnectome.org)
Structural networks consist of axonal projections and pathways. (biosourcesoftware.com)
First, given that functional connectivity is anchored and constrained by the structural connectome, we hypothesized that pathways between different layers, which have been shown to have a structural basis in invasive studies must have higher functional (synchronized and undirected) connectivity inferred from layer-resolved fMRI. (auburn.edu)
Specifically, we illustrate this framework by characterizing layer-specific directional functional pathways in the corticogeniculate network of the human visual system by obtaining sub-millimeter fMRI at 7T using a task that engages the magnocellular pathway between LGN and the primary visual cortex. (auburn.edu)
ii) feedforward (LGN→ Layers VI/IV, Layer IV→ Layer VI) and feedback (Layer VI→ LGN) functional pathways, known to exist from invasive animal studies, can be inferred using dynamic directional connectivity models of fMRI and could potentially explain the mechanism underlying center-surround inhibition as well as gain control by Layer-VI in the human visual system. (auburn.edu)
The elaborate and complicated networks in the brain, their different pathways and subsystems, process everything we see, our movements, memories and feelings," said Hongkui Zeng , Ph.D., Executive Director of Structured Science at the Allen Institute for Brain Science, a division of the Allen Institute, and senior author of the study. (alleninstitute.org)

Several measures can be used to characterize the topological architecture of the brain's networks. (johnshopkins.edu)
as functional connectivity is averaged over longer time periods, it may converge onto structural connectivity, although it is important to remember that structural and functional connectivity are different measures and may thus yield connectomes with different values of some topological parameters (Zalesky et al. (biosourcesoftware.com)

A deeper knowledge of these principles gives us insight the connectome's role in shaping human behavior and cognition and helps reveal how abnormal connectivity can lead to disease. (indiana.edu)
Dr Duncan Astle is a Programme Leader at the MRC Cognition and Brain Sciences Unit, University of Cambridge. (ox.ac.uk)
Ultimately determining how the brain is wired as an adult, changes in cognition and behaviour for developmental diseases such as schizophrenia, autism, and ADHD are linked to changes in the network organisation in the brain. (neurosciencenews.com)

In this article we attempt to trace the development of certain anatomical and physiological concepts at the origins of modern definitions of the connectome. (nih.gov)
These results demonstrate a novel link between neuroinflammation and vascular physiological dysfunction in the cerebral white matter, and could indicate enduring loss of vascular compliance associated with imperfect repair of blood-brain barrier damage after resolution of acute neuroinflammation. (biorxiv.org)
Together, these findings indicate that the influx of peripheral inflammatory cells into the brain via the cerebral venous system leads to enduring anatomical and physiological changes to the vessels. (biorxiv.org)

Rightward asymmetry can be seen in the right central sulcus (potentially suggesting increased connectivity between motor and somatosensory cortices in the left side of the brain), lateral ventricle, entorhinal cortex, amygdala and temporo-parieto-occipital area. (wikipedia.org)
Edge-centric functional network representations of human cerebral cortex reveal overlapping system-level architecture. (indiana.edu)
For this purpose, we build a large scale computational model that consists of the following elements of the basal ganglia network: subthalamic nucleus (STN), globus pallidus (external and internal parts) (GPe-GPi), extended with the striatum, thalamus and motor cortex (MC) areas, integrating connectivity from multimodal imaging data. (frontiersin.org)
Ulloa A , Horwitz B . Embedding Task-Based Neural Models into a Connectome-Based Model of the Cerebral Cortex. (neurotree.org)
Before the connectivity analysis, we applied a surface-based laminar analysis pipeline to process high-resolution, sub-millimeter MRI data obtained at 7T, and to delineate different layers of the human cortex. (auburn.edu)
The regions of the brain showing the high predictive power of symptom severity were distributed across the cortex, with stronger bearings in the frontal, motor and occipital cortices. (biorxiv.org)

The proposed framework explicitly models the interactions between structural and functional connectivity measures thereby improving anatomical circuit estimation. (umn.edu)
Her main research interest is non-invasive mapping of structural and functional connectivity in the developing brain, from premature neonates to adolescents and young adults. (ucsf.edu)
Imaging studies of major depressive disorder have reported structural and functional abnormalities in a variety of spatially diverse brain regions. (psychiatryonline.org)
In the present study, the authors applied a novel multimodal meta-analytic approach to test the hypothesis that major depression exhibits spatially convergent structural and functional brain abnormalities. (psychiatryonline.org)
The capacity of the brain, which allows our species to be highly sophisticated in speech, behavior, and thought, has long stunned scientists regarding its structural and functional makeup. (simplyneuroscience.org)
In that sense, it serves a purpose analogous to that of the long-running Martinos Center's Functional MRI Visiting Fellowship Program (fMRIVFP), with the exception that the domain will be structural and functional connectivity of myelinated fiber tracts within the living human brain. (martinos.org)
A variety of imaging modalities, including structural and functional magnetic resonance imaging (MRI) and positron emission tomography (PET) studies of cerebral metabolism, have shown characteristic changes in the brain of patients with Alzheimer disease in prodromal and even presymptomatic states. (medscape.com)

The Human Connectome Project and Connectome Coordination Facility are funded by the National Institutes of Health, and all information in this site is available to the public domain. (humanconnectome.org)

abstract = "Purpose: The structural connectome is a comprehensive structural description of the network of elements and connections forming the brain. (johnshopkins.edu)

Optimally controlling the human connectome: the role of network topology. (indiana.edu)
The structural network of the human brain has a rich topology which many have sought to characterise using standard network science measures and concepts. (hdruk.org)
These efficiency promote a charity getting a beneficial principled knowledge of guidance import across systems and also reveal that alterations in directionality habits round the states away from human understanding was driven from the alterations off head network topology. (dazrozpharma.com)

Whole-brain anatomical networks: does the choice of nodes matter? (crossref.org)
Dividing the connectomes into four tiers based on degree magnitudes indicates that the most complex nodes are neither those with the highest nor lowest degrees but are instead found in the middle tiers. (hdruk.org)
Exploiting the structural properties of the network, we identify nodes of strong influence, which are potential targets for Deep Brain Stimulation (DBS). (frontiersin.org)
Furthermore, based on a modularity algorithm, network communities are detected as set of nodes with high-interconnectivity. (frontiersin.org)
Relatively subtle changes within the wiring rules of this computational framework give rise to differential developmental trajectories, because of small biases in the preferential wiring properties of different nodes within the network. (ox.ac.uk)
Logical, computational, and you can empirical sitios de citas gorditas gratis results demonstrate that network nodes with connections (we.e., high values) provides big amplitudes and so are directional objectives (stage lag) instead of present (phase direct). (dazrozpharma.com)
Analytical, computational, and you can empirical efficiency most of the show that network nodes with increased relationships (i.age. (dazrozpharma.com)

One such study conducted at the University of California San Diego's Kavli Institute for Brain and Mind demonstrates that fruit flies exhibit complex cognitive processes. (whatsthatbug.com)
Principles of time-varying functional network reconfiguration and its relationship to ongoing cognitive processes. (indiana.edu)
It limits our ability to fully appreciate how evolution has shaped our brain, especially in systems associated with unique human cognitive capabilities that lack anatomical homologues in other species. (harvard.edu)
Our findings suggest that the establishment of the default mode network, as the apex of a cognitive hierarchy, has changed in a complex manner during human evolution - even within subnetworks. (harvard.edu)
Much of the work in cognitive neuroscience is shifting from a focus on single brain regions to a focus on the connectivity between multiple brain regions. (researchgate.net)
whereas exteroceptive processes related to cognitive control have been linked to the executive-control network (ECN). (researchgate.net)
We used structural neuroimaging collected from 479 children (299 boys, ranging in age from 62 to 223 months) who are members of an intentionally diverse cohort of struggling learners to explore how different features of macroscopic brain organisation are associated with diverse cognitive trajectories. (ox.ac.uk)
The more children's brains were critically dependent on hubs, the better their cognitive skills. (ox.ac.uk)
Full open access research for "Mechanisms of Connectome Development" by Marcus Kaiser in Trends in Cognitive Sciences . (neurosciencenews.com)
Current neurofeedback protocols allow us to train networks involved in cognitive functions like attention or psychological disorders like depression using multiple electrodes simultaneously. (biosourcesoftware.com)
Each local cognitive, sensory processing or emotional network type produces oscillatory activity and contains internal stabilizing characteristics. (biosourcesoftware.com)
also showed that the cingulo-operculum subnetwork demonstrated more ties with other functional subnetworks in association with neuroticism, whereas cognitive control networks in the default mode network showed less efficient information processing 14 . (nature.com)

We demonstrated that the post-deconvolution connectivity analysis in the latent neural space aligned more closely with the underlying anatomical connections compared to connectivity obtained from original fMRI data. (auburn.edu)

Neurovascular dysfunction, including blood-brain barrier (BBB) breakdown and cerebral blood flow (CBF) dysregulation and reduction, is increasingly recognized as contributing to Alzheimer disease. (medscape.com)

This research involves network modeling and analysis using a diverse set of mathematical tools that includes elements of graph theory, information theory, and dynamical systems theory. (indiana.edu)
Graph-theoretical analyses have shown that the functional connectivity in the human brain is divided into well-organized modules or subnetworks which are densely connected within themselves and sparsely connected to each other. (biorxiv.org)

A Systematic Review of MRI Studies and the "Emotional paiN and social Disconnect (END)" Brain Model of Suicidal Behavior in Youth. (ucsf.edu)

Organizing principles of whole-brain functional connectivity in zebrafish larvae. (indiana.edu)
Furthermore, each of these localized, dynamic connectivity states is associated with global changes in the whole-brain functional connectome. (stanford.edu)

Second, unidirectional anatomical projections at the layer level, which support feedback and feedforward interactions must be inferred using effective (directional, time-lagged) connectivity derived from layer resolved fMRI. (auburn.edu)

Retrieved June 13, 2017 from https://neurosciencenews.com/time-space-brain-development-6902/[/cbtab][cbtab title="Chicago"]Newcastle University "The Importance of Time and Space in Brain Development and Disease. (neurosciencenews.com)

Network Neuroscience (2021) 5 (3): 646-665. (mit.edu)

Ulloa A , Horwitz B . Quantifying differences between passive and task-evoked intrinsic functional connectivity in a large-scale brain simulation. (neurotree.org)

We find that parts of the connectome consistently cluster as densely connected components, while other parts consistently result in clusters with similar connections. (ru.nl)

The fourth in a series of workshops, co-hosted by the BRAIN Initiative and the Department of Energy Office of Science, bringing together researchers with broad expertise to discuss the state of the art in mapping complete neural circuits, the opportunities for advancing connectomics technologies, and the challenges to be overcome to generate comprehensive maps of brain connectivity. (nih.gov)
Spatial mapping of the brain regions in each hierarchical tier reveals consistency with the current anatomical, functional and neuropsychological knowledge of the human brain. (hdruk.org)
Chu, SH , Parhi, KK & Lenglet, C 2018, ' Function-specific and Enhanced Brain Structural Connectivity Mapping via Joint Modeling of Diffusion and Functional MRI ', Scientific reports , vol. 8, no. 1, 4741. (umn.edu)
Mapping the functional connectome has the potential to uncover key insights into brain organisation. (stanford.edu)

Critically, we find cross-species similarity in functional organization reflects a gradient of evolutionary change that decreases from unimodal systems and culminates with the most pronounced changes in posterior regions of the default mode network (angular gyrus, posterior cingulate and middle temporal cortices). (harvard.edu)

In the mid-19th century scientists first began to make discoveries regarding lateralization of the brain, or differences in anatomy and corresponding function between the brain's two hemispheres. (wikipedia.org)
We also argue that many contemporary maps are inaccurate surrogates of the true anatomy and a comprehensive connectome of the human brain remains a far distant point in the history to come. (nih.gov)

The modular organization of human anatomical brain networks: Accounting for the cost of wiring. (indiana.edu)

Thus, the spatial layout of correlations from different origins may aid in brain parcellation. (humanconnectome.org)
Several studies have successfully implemented this idea in humans using diffusion weighted MRI, allowing parcellation to be conducted in vivo. (ru.nl)
Using the model we are able to obtain a parcellation of the human brain whose clusters may adhere to either interpretation. (ru.nl)

Functional Geometry of Human Connectomes. (naturalgenesis.net)

Macroscopic brain organisation emerges early in life, even prenatally, and continues through adolescence and into early adulthood. (ox.ac.uk)
We subsequently developed a computational framework, using generative network modelling (GNM), to model the emergence of this kind of connectome organisation. (ox.ac.uk)
Nevertheless, those one-handers who more frequently use their residual (handless) arm for typically bimanual daily tasks also showed more symmetrical functional connectivity of the hand region, demonstrating that adaptive behaviour drives long-range brain organisation. (elifesciences.org)

Now, we compiled data of the same participant acquired across more than ten years and present an extension to our previous dataset containing multiple additional contrasts with ultrahigh isotropic spatial resolution and (mostly) full brain coverage (Fig. 1 ). (nature.com)
While this has traditionally been done using invasive techniques, recent improvements in the spatial resolution of anatomical and functional MRI may enable non-invasive investigation of the connectional architecture at the laminar level. (auburn.edu)

The member universities of the Human Connectome Project take privacy very seriously, whether dealing with participant data or the data of those visiting this website. (humanconnectome.org)
We performed supervised training of the CNN on the T1w images of control participants ( n = 1049) from the Human Connectome Project (HCP) repository and automatically generated algorithm-based optic chiasm masks. (frontiersin.org)
Results on Human Connectome Project (HCP) data demonstrate the benefits of the approach by successfully identifying function-specific anatomical circuits, such as the language and resting-state networks. (umn.edu)
This database was founded as part of the SenseLab project which was supported by the Human Brain Project (NIDCD, NIMH, NIA, NICD, NINDS), by MURI (Multidisciplinary University Research Initiative), and by R01 DC 009977 from the National Institute for Deafness and other Communication Disorders. (modeldb.science)
Henry Markram is a professor of neuroscience at the Swiss Federal Institute for Technology ( EPFL ), director of the Laboratory of Neural Microcircuitry ( LNMC ) and the Founder and Director of the Blue Brain Project. (epfl.ch)
In 2005, he launched the Blue Brain Project to digitally reconstruct and simulate the mouse brain. (epfl.ch)
Markram is also the founder of the Brain Mind Institute and the founder of the European Human Brain Project, one of two ten-year one billion Euro Flagship Projects selected in January 2013 by the European Commission. (epfl.ch)

Studies may be either hypothesis-generating (unbiased discovery) or hypothesis-testing in design and may utilize in vivo, in situ or in vitro experimental paradigms, e.g., model organisms or human cell-based assays. (nih.gov)

Neurobiologically-constrained generative models of brain networks and applications to brain development. (indiana.edu)

Recent studies reveal that flies, specifically fruit flies, exhibit more advanced brain functions than previously thought. (whatsthatbug.com)
Quantitative EEG (qEEG) normative databases can reveal the key parts of a network that need training and the required direction. (biosourcesoftware.com)

Little is known about how different CNVs conferring risk for the same condition may affect subcortical brain structures and how these alterations relate to the level of disease risk conferred by CNVs. (bvsalud.org)
Alterations in brain connections have been seen in Alzheimer's disease, Parkinson's and several other brain diseases and disorders. (alleninstitute.org)

A joint structural-functional brain network model is presented, which enables the discovery of function-specific brain circuits, and recovers structural connections that are under-estimated by diffusion MRI (dMRI). (umn.edu)
Incorporating information from functional MRI (fMRI) into diffusion MRI to estimate brain circuits is a challenging task. (umn.edu)

Prasun Kumar Roy is an academic researcher from National Brain Research Centre. (typeset.io)

Using a signal modelling technique, we assessed the anatomical distribution of white matter BOLD signal abnormalities and detected reduced power in the periventricular white matter, a region of known venous damage in multiple sclerosis patients. (biorxiv.org)
Despite the relevance of the white matter venous system to multiple sclerosis pathology, relatively few studies have directly studied venous pathology in the multiple sclerosis brain. (biorxiv.org)
We used diffusion-weighted imaging (DWI) to construct whole-brain white-matter connectomes. (ox.ac.uk)
Tree-based metrics showed linear and non-linear correlation across adulthood and are in close accordance with results from previous histopathological characterizations of the changes in white matter integrity in the aging brain. (typeset.io)
Connectomics, first and foremost, is a technological and computational feat. To build maps of brain connectivity, both functional and structural imaging insights are required: functional data is obtained from functional magnetic resonance imaging (fMRI), which renders an image of blood flow activity in the white matter and deeper brain regions, indicating which areas are active. (simplyneuroscience.org)
They will also receive a firm grounding in the power and limitations of using diffusion-sensitive MRI to detect and organize the anatomical structure of white matter tracts in the living human brain. (martinos.org)

The organizational network changes in the human brain across the lifespan have been mapped using functional and structural connectivity data. (typeset.io)

The human neocortical gray matter contains cytoarchitectonically distinct layers, with notable differences in their structural connectivity with the rest of the brain. (auburn.edu)

This is a unique and comprehensive collection comprising a "human phantom" dataset. (nature.com)
Whole-brain networks' minimum spanning trees were determined in a dataset of diffusion-weighted images from 382 healthy subjects, ranging in age from 20.2 to 86.2 years. (typeset.io)
The original iteration of that dataset, first debuted in 2014 , captured connections between brain regions. (alleninstitute.org)

6.95 Structural Brain Connectivity Correlates of Suicidal Ideation in Adolescents. (ucsf.edu)
Understanding the neural correlates of the neurotic brain is important because neuroticism is a risk factor for the development of psychopathology. (nature.com)
We found that whole-brain flexibility correlates with static modularity only in TD. (biorxiv.org)

Integrating electrophysiological and anatomical experimental data to create a large-scale model that simulates a delayed match-to-sample human brain imaging study. (modeldb.science)
Integrating brain function and structure in the study of the human attentional networks. (googleapis.com)

Here we test the hierarchical complexity of the human structural connectomes of a group of seventy-nine healthy adults. (hdruk.org)
Parlatini V, Radua J, Dell'Acqua F, Catani M, Thiebaut de Schotten M, Murphy D. Attentive networks are right-lateralized in adults with ADHD and differentially associated with neuropsychological profiles in responders and non-responders to methylphenidate. (googleapis.com)

Thus, we have compiled the most comprehensive and high quality MRI data repository of a single human participant to date. (nature.com)

In functional networks , there is correlated activity between regions over time. (biosourcesoftware.com)

Methods: We discuss the different steps and emphasize key technical aspects required for the successful reconstruction, analysis, and visualization of the pediatric structural connectome using current state-of-the-art neuroimaging and post-processing techniques. (johnshopkins.edu)
Finally, we provide an overview of various visualization methods of the structural connectome in children. (johnshopkins.edu)
In this program, participants will learn about the technical challenges in acquisition, data processing and visualization of brain networks via functional MRI data. (martinos.org)

Anatomy5

Diseases1

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Psychiatry and Psychology2

Phenomena and Processes2

Information Science2

Cortical10

Tractography5

Mammalian brain7

Models of the human connectome2

Neural networks5

Neurons10

Neuronal4

20233

20222

Patterns12

Pathways6

Topological2

Cognition3

Physiological3

Cortex6

Structural and functional7

Coordination Facility1

Abstract1

Topology3

Nodes7

Cognitive12

FMRI data1

Cerebral1

Graph2

Behavior1

Whole-brain functional2

Projections1

20171

20211

Task-evoked1

Densely connected1

Mapping4

Critically1

Anatomy2

Organization of human1

Parcellation3

Geometry1

Organisation3

Spatial resolution2

Project7

Hypothesis1

Generative1

Reveal2

Alterations2

Circuits2

National Brain1

White matter6

Connectivity data1

Differences1

Dataset3

Correlates3

Integrating2

Adults2

Repository1

Functional networks1

Visualization3