• afzelii
  • However, a correlation has been found which presents data suggesting that B. burgdorferi found in the United States is the most arthritogenic, whereas the B. afzelii and B. garnii found in Europe and Asia tend to give signs more consistent with dermatological and neuroborreliosis symptoms. (davidson.edu)
  • Neurologic
  • Neurologic symptoms of neuroborreliosis include the meningoradiculitis (which is more common in European patients), cranial nerve abnormalities, and altered mental status. (wikipedia.org)
  • According to neuropsychiatrist Brian Fallon, MD, director of theSurveys University Lyme Disease Research Center and principal investigator of an NIH-funded study on chronic Lyme disease, about 15 percent of infected patients (not necessarily of children) develop objective neurologic abnormalities, most commonly displaying part of the triad of aseptic meningitis, cranial neuritis, and motor sensory radiculitis. (borrelioosi.net)
  • Alzheimer's
  • We and others have examined patients with various neurodegenerative and behavioral neurological conditions, such as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Alzheimer's disease (AD) and Autistic Spectrum Disorders ([ASD], including Autism, Attention Deficit Disorder, Asperger Syndrome), and found evidence for systemic intracellular bacterial and viral infections in a majority of patients. (townsendletter.com)
  • They include: Alzheimer's disease Acute disseminated encephalomyelitis Viral meningitis Multiple sclerosis Bell's palsy Neuroborreliosis presenting with symptoms consistent with amyotrophic lateral sclerosis has been described. (wikipedia.org)
  • endemic
  • Prevalence of antibodies against Borrella species in patients with unclassified uveitis in regions in with Lyme disease is endemic' Clin.Diag.Labo.Immunol.2. (nii.ac.jp)
  • Lyme disease is most endemic in Northern Hemisphere temperate regions, but sporadic cases have been described in other areas of the world. (wikipedia.org)
  • TBRF is endemic to sub-Saharan Africa, and the most prevalent Borrelia species in this region are B . duttonii in the eastern region and B . crocidurae in the western region ( 3 - 5 ). (cdc.gov)
  • This might be due to the very low incidence in an endemic region (0.2%, CI 95% 0.0% to 1.1%) as demonstrated in 517 patients hospitalized for psychiatric diseases. (blogspot.com)
  • A soft-bodied tick ( Ornithodoros ) transmits multiple Borrelia species that cause endemic relapsing fever, whereas the human body louse transmits B recurrentis, which causes an epidemic form of relapsing fever. (medscape.com)
  • Ixodes
  • Over 200 vectors carry the Ixodes tick, which is the most commonly known insect spreading Lyme disease. (lymebook.com)
  • Des Vignes F, Piesman J, Heffernan R, Schulze TL, Stafford KC 3rd, Fish D. Effect of tick removal on transmission of Borrelia burgdorferi and Ehrlichia phagocytophila by Ixodes scapularis nymphs. (springer.com)
  • patients
  • showed that patients with neuroborreliosis demonstrate a blood brain barrier disturbance with 62 % showing an elevated albumin ratio and 60 % revealing an increased IgG index, indicative of intrathecal IgG synthesis. (upmc.edu)
  • Not all patients with Lyme disease have all symptoms, and many of the symptoms are not specific to Lyme disease, but can occur with other diseases, as well. (wikipedia.org)
  • Patients with neurodegenerative diseases and behavioral disorders often have systemic bacterial, viral, and/or fungal infections that are important in disease progression and severity. (townsendletter.com)
  • this rash occurs in 75% of patients infected with Lyme disease and tends to resolve from the inside-out, leaving a bull's eye mark on the skin (Frey 2002). (davidson.edu)
  • Use of bisphosphonates in patients with conditions or diseases affecting renal function is not recommended. (issuu.com)
  • However, about 10-15% of patients with Lyme arthritis fail the initial course of antibiotics, and some of those develop a chronic inflammatory arthritis optimally treated with local or systemic immunosuppressive agents. (springer.com)
  • Although most patients with Lyme/tick-borne disease do not become violent, a small percent of patients who become infected develop a type of neurological dysfunction that can increase their risk of aggressiveness. (psychologytoday.com)
  • In working with a number of patients with Lyme/tick-borne diseases it is apparent to many clinicians these conditions can cause reduced frustration tolerance, irritability, depression , cognitive impairments and mood swings, but more significantly, in a few patients, suicidal and aggressive tendencies. (psychologytoday.com)
  • We conducted retrospective and prospective surveys of patients with unexplained fever (suspected TBRF) in northwestern Morocco during 2000-2006 and used 2 genomic regions of Borrelia spp. (cdc.gov)
  • Of 75,950 patients, 84 had Borrelia spp. (cdc.gov)
  • All patients were screened for Borrelia spp. (cdc.gov)
  • 11 In contrast, if the SF-36 was used to determine Quality of Life (QOL) in post-Lyme patients, the average SF-36 physical component summary (40±9, range 29-44) and mental component summary (39±14, range 23-46) of the QOL assessment were worse than the general USA population, and they could be significantly improved by anti-Lyme antibiotics (46% versus 18%, p =0.007). (blogspot.com)
  • Dr. Jemsek s Clinic sees more new patients for Lyme Disease than any other facility in the country. (lymediseaseaction.org.uk)
  • In 1998, he received the top honor in the state of North Carolina from its governor for his commitment to HIV patients. (lymediseaseaction.org.uk)
  • More recently he became involved in the care of patients with Lyme Disease and he is a member of the International Lyme and Associated Diseases Society (ILADS). (lymediseaseaction.org.uk)
  • The sensitivity for samples classified as acute disease was 35.4%, with a corresponding sensitivity of 64.5% for samples from patients defined as convalescent. (dovepress.com)
  • antibiotics
  • In the US, neuroborreliosis is typically treated with intravenous antibiotics which cross the blood-brain barrier, such as penicillins, ceftriaxone, or cefotaxime. (wikipedia.org)
  • In addition to the general indications for all members of the tetracycline antibiotics group, doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease, acne, rosacea, and rickettsial infections. (wikipedia.org)
  • Molecular
  • 1 These diseases are characterized by molecular changes in nerve cells that result in nerve cell degeneration and, ultimately, nerve dysfunction and cell death, resulting in neurological signs and symptoms and, eventually, dementia. (townsendletter.com)
  • Molecular detection specific for the 16S rRNA gene identified Borrelia hispanica . (cdc.gov)
  • neurological
  • 1-5 One of the biochemical changes found in essentially all neurological degenerative diseases is the over-expression of oxidative free radical compounds (oxidative stress) that cause lipid, protein, and genetic structural changes. (townsendletter.com)
  • An attractive model for neurodegeneration resulting in neurological disease involves the action of toxic products produced as a result of chronic bacterial and/or viral infections. (townsendletter.com)
  • Can microbes and immune reactions to them actually contribute to cognitive decline, degenerative neurological disease, developmental disabilities, mental illness, personality changes and, at the most extreme, even violent and criminal behavior? (psychologytoday.com)
  • infections
  • 1 In addition to genetic changes and changes in gene expression, it is thought that nutritional deficiencies, head trauma, environmental toxins, chronic bacterial and viral infections, autoimmune immunological responses, vascular diseases, accumulation of fluid in the brain, changes in neurotransmitter concentrations, and other causes are involved in various neurodegenerative diseases. (townsendletter.com)
  • 8 Such infections may also cause disease progression, and since they are usually systemic, they could affect the immune system and other organ systems, resulting in systemic signs and symptoms. (townsendletter.com)
  • In the first part of this review we considered neurodegenerative and neurobehavioural diseases and the findings that these diseases commonly are associated with systemic and central nervous system bacterial and viral infections. (blogspot.com)
  • 1 In this second part we continue with psychiatric diseases, autoimmune diseases, fatiguing illnesses, and other chronic diseases where chronic infections play an important role. (blogspot.com)
  • Africa
  • With so many vectors, the underlying assumption behind this checklist is that Lyme is not rare in North America, Europe, South America, Russia, Africa or Asia. (lymebook.com)
  • The disease is rarely detected in northern Africa and Mediterranean countries ( 3 , 6 , 7 ). (cdc.gov)