• For further evaluation of the extension of the mass and metastasis control, a pre- and postcontrast computed tomography (CT) of the head and thorax was performed. (thieme-connect.com)
  • As temporal bone computed tomography (CT) has become more sophisticated, more abnormalities of the middle and inner ear have been found. (ochsnerjournal.org)
  • Temporal bone computed tomography revealed expansile soft tissue densities and diffuse erosive destruction on left temporal bone ( Fig. 3 ). (ejao.org)
  • Temporal bone computed tomography. (ejao.org)
  • Computed tomography (CT) showed regular-shaped defects in the bilateral temporal bones, right parietal bone, bilateral frontal bones in the upper-medial orbital wall, and particularly in the occipital bone. (balkanmedicaljournal.org)
  • The mastoid part of the temporal bone is the posterior (back) part of the temporal bone, one of the bones of the skull. (wikipedia.org)
  • The tympanic antrum is bounded above by a thin plate of bone, the tegmen tympani, which separates it from the middle fossa of the base of the skull, below by the mastoid process, laterally by the squama just below the temporal line, and medially by the lateral semicircular canal of the internal ear, which projects into its cavity. (wikipedia.org)
  • Both dogs presented with a space-occupying mass in which excisional surgery without the use of implants would have resulted in incomplete closure due to extensive bone defects of the skull. (thieme-connect.com)
  • The minor in this case sustained injuries including a basak skull fracture, a pons-tear injury, and temporal bone fracture. (joelhschwartz.com)
  • DC is another broadly used operation for STBI rescue, which involves the removal of the frontal, parietal and temporal skull to expand fixed cranial cavity. (biomedcentral.com)
  • The temporomandibular joints (TMJ) connect the temporal bones on each side of the skull to the mandible, or lower jawbone. (al-aswaddental.com)
  • Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. (ucdenver.edu)
  • It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull). (ucdenver.edu)
  • This is a series of X-rays of the skull, axial skeleton and proximal long bones. (the-medical-dictionary.com)
  • More detailed spatial and temporal correlations between altered mRNA levels and tissue plasticity may further delineate the molecules responsible for the control of bone mass and morphology. (elsevierpure.com)
  • This bone turnover comprises the temporal and spatial coordination of two processes performed in bone remodeling units at discrete sites throughout the skeleton: removal of old and damaged bone by osteoclasts, called resorption, which can last 4-6 weeks, followed by new bone formation by osteoblasts, which produce collagen and mineralized bone matrix in a process lasting 4-5 months [ 3 ]. (biomedcentral.com)
  • Spatial and temporal changes in groundwater manganese and infant mortality in North Carolina. (cdc.gov)
  • Incorporating bone-suppression functions can improve detection of subtle pulmonary lesions on temporal subtraction digital chest radiographs. (auntminnie.com)
  • On one end, the clinical spectrum includes an acute, fulminant, disseminated disease called Letterer-Siwe disease, and, on the other end, solitary or few, indolent and chronic lesions of bone or other organs called eosinophilic granulomas. (medscape.com)
  • The intermediate clinical form called Hand-Schüller-Christian disease is characterized by multifocal, chronic involvement and classically presents as the triad of diabetes insipidus, proptosis, and lytic bone lesions. (medscape.com)
  • In the present study, we designed a prospective, randomized, controlled trial to clarify the effect of decompressive craniectomy in severe traumatic brain injury patients with mass lesions. (biomedcentral.com)
  • In this trial, 336 patients with traumatic mass lesions will be randomly allocated to a therapeutic decompressive craniectomy group or a prophylactic decompressive craniectomy group. (biomedcentral.com)
  • This study will provide evidence to optimize primary decompressive craniectomy application and assess outcomes and risks for mass lesions in severe traumatic brain injury. (biomedcentral.com)
  • En bloc resection of the ear canal with sparing of the facial nerve is done when lesions are limited to the canal and have not invaded the middle ear. (msdmanuals.com)
  • We found extensive volumetric gray matter decreases, including large areas covering the temporal and frontal poles and around the orbits. (nature.com)
  • To the best of our knowledge, this is the first described case of multiple occipital, parietal, temporal, and frontal foramina in the cranium. (balkanmedicaljournal.org)
  • Leukaemic bone marrow biomimicry. (imperial.ac.uk)
  • Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the presence of cells with characteristics similar to bone marrow-derived Langerhans cells juxtaposed against a backdrop of hematopoietic cells, including T-cells, macrophages, and eosinophils. (medscape.com)
  • At the cellular level, the mesenchymal stem cell pool in the bone marrow niche shows a biased differentiation into adipogenesis at the cost of osteogenesis. (biomedcentral.com)
  • A bone marrow biopsy is usually performed to estimate the percentage of bone marrow occupied by plasma cells. (the-medical-dictionary.com)
  • Our work-up included laboratory tests, radiographic examinations, analysis of bone marrow aspiration, and histopathologic evaluations. (the-medical-dictionary.com)
  • The incidence of atraumatic fractures in patients who receive supraphysiologic glucocorticoid therapy is 30 to 50%.5,6 The chronic use of GC is associated with a lower bone mineral density (BMD) and a higher risk of bone fractures in a dose-response relationship. (uveitis.org)
  • [ 12 ] This risk of fractures or bone deformity is higher in the long bones (eg, femur, tibia, and humerus), but all the bones can be affected. (medscape.com)
  • Aging is a high risk factor for the development of osteoporosis, a multifactorial age-related progressive disease characterized by reduced bone mass and increased risk of fractures. (biomedcentral.com)
  • As a consequence, bone aging is the main risk factor for primary osteoporosis, characterized by a reduction in bone mineral density, predisposing the elderly population to an increased risk of fractures. (biomedcentral.com)
  • Abnormalities in other parts of the body, such as malformed bones of the spine (vertebrae), abnormally shaped kidneys, and heart defects, may also occur in people with craniofacial microsomia. (medlineplus.gov)
  • The surgical treatment of temporal bone defects, as well as the recognition and treatment of accompanying intracranial hypertension, provides the greatest success rate in preventing recurrence. (medscape.com)
  • Given that intracranial hypertension has been implicated as a significant factor in temporal encephalocele formation, [ 7 , 10-12 , 15 ] we hoped to clarify this correlation by reviewing a series of tegmen defects repaired surgically and the associated ICP measurements in these patients. (medscape.com)
  • Bone mineral density testing is the most reliable tool to assess fracture risk. (uveitis.org)
  • It has proven to be a reliable indicator of risk for developing osteoporotic fracture, and an efficient tool to assess response to treatment of bone loss. (uveitis.org)
  • As a consequence of this bone fragility, patients have an increased (~50%) risk of fracture. (medscape.com)
  • The most common surgical indications are fracture of a weightbearing bone and progressive disease. (medscape.com)
  • The hippocampus is a section of the brain in the temporal lobe, below the cerebral cortex. (saveourbones.com)
  • IGF-1 has also been implicated in the maintenance of bone mass during late adulthood and aging, as decreases in serum IGF-1 levels appear to correlate with decreases in bone mineral density (BMD). (elsevierpure.com)
  • Context: In a previous community-based, cross-sectional study, males with type 1 diabetes (T1D) had lower bone mineral density (BMD) than did matched people without diabetes but females with T1D had normal BMD. (edu.au)
  • Osteoporosis Slideshow Osteoporosis is a disease characterized by low bone mass and density. (manage-your-energy.com)
  • The well-defined contours, absence of a soft tissue component, and normal structure and density of the adjacent calvarial bones all pointed to a congenital defect. (balkanmedicaljournal.org)
  • accordingly, a decrease in bone mineral density occurs. (biomedcentral.com)
  • Caffeine consumption has been studied as a risk factor for many diseases and conditions, including hypertension, bone density, cardiovascular diseases, various cancers, reproduction and developmental abnormalities, and mental and behavioral disorders. (cdc.gov)
  • Schwannomas of the jugular foramen, usually with origin from the ninth nerve, are rare, but the presenting symptoms may be similar to those of a vestibular schwannoma owing to mass effect by tumor growth in the posterior cranial fossa (2-4) . (ajnr.org)
  • The petrous apex lies at the anterior superior portion of the temporal bone. (medscape.com)
  • An axial CT scan of the temporal bone shows an air-fluid level within the right petrous apex and fluid within the middle ear space and mastoid. (medscape.com)
  • CN IX then enters the jugular foramen after coursing through a groove in the inferior aspect of the petrous bone. (medscape.com)
  • After entering the infratemporal fossa between the medial pterygoid muscle and mandible, the chorda tympani leaves the lingual nerve and crosses the spine of the sphenoid bone, to proceed to the petrous temporal bone through the petrotympanic fissure (canal of Huguier). (medscape.com)
  • He utilizes all types of epilepsy surgery techniques, ranging from traditional resection/disconnection and neuromodulation surgery, such as lesionectomy, anterior temporal lobectomy, corpus callosotomy, functional hemispherotomy, and vagal nerve stimulation, to minimally invasive MRI-guided laser interstitial thermal therapy (LITT), to newer neuromodulation techniques, such as responsive neurostimulation (RNS) and deep brain stimulation (DBS). (rutgers.edu)
  • Deeper invasion requires a more significant temporal bone resection. (msdmanuals.com)
  • If bone resorption is simultaneously increased (by other medications, by the illness for which the glucocorticoids are prescribed, or by concomitant circumstances such as estrogen lack), then bone loss is particularl rapid.Dosages of GC >5 mg /day are associated with accelerated bone loss in elderly men and women8. (uveitis.org)
  • GC also can induce androgen deficiency by pharmacological suppression of adrenal function13, and androgen deficiency increases bone resorption. (uveitis.org)
  • In addition, CT-guided percutaneous biopsy was judged to be effective for obtaining tissue samples for soft tissue and bone mass biopsies. (auntminnie.com)
  • This shows expansile soft tissue densities and diffuse erosive destruction on the left temporal bone. (ejao.org)
  • Object Thinning of the tegmen tympani and mastoideum components of the temporal bone may predispose to the development of meningoencephaloceles and spontaneous CSF leaks. (medscape.com)
  • The collection of biological samples from patients with ocular disorders is an integral part of many research programs at Mass. Eye and Ear. (masseyeandear.org)
  • In seven patients, CT scans with bone algorithm showed an enlarged jugular foramen with sharply rounded bone borders and a sclerotic rim. (ajnr.org)
  • CT scans without and with contrast enhancement were available in eight patients, and CT scans with bone algorithm were available in seven of these patients. (ajnr.org)
  • We performed a retrospective medical records review of 12 patients with CHARGE syndrome, identified between 1990-2011 at Princess Margaret Hospital for Children in Western Australia, who underwent temporal bone CT for evaluation of hearing loss. (ochsnerjournal.org)
  • Results The average body mass index (BMI) among all patients was 33.2 ± 7.2 kg/m 2 . (medscape.com)
  • Results: After adjustment for age, body mass index (BMI), and renal function, there was no temporal change in BMD at the hip or forearm in the males (P ≥ 0.12), but lumbar spine BMD increased (P = 0.009). (edu.au)
  • Additional findings are: a raised calcium (when myeloma cells are breaking down bone, releasing calcium into the bloodstream) and decreased renal function, which may be due to paraprotein deposition in the kidney). (the-medical-dictionary.com)
  • Fibrous dysplasia accounts for about 5% of all benign bone tumors. (medscape.com)
  • Nonchromaffin paragangliomas (chemodectomas) arise in the temporal bone from glomus bodies in the jugular bulb (glomus jugulare tumors) or the medial wall of the middle ear (glomus tympanicum tumors). (msdmanuals.com)
  • The groove for the transverse sinus is separated from the innermost of the mastoid cells by a very thin lamina of bone, and even this may be partly deficient. (wikipedia.org)
  • And presents a narrow longitudinal sinus, the superior tarsal bones are four inches. (ghossainsbakery.com)
  • Adult female mice (BALB/cByJ) were subjected to catabolic (disuse) and anabolic (45 Hz, 0.3g vibration for 10 min/day) signals, and changes in the mRNA levels of thirteen genes were compared to altered indices of bone formation. (elsevierpure.com)
  • These data confirm the complexity of the bone remodeling process, both in terms of the number of genes involved, their interaction and coordination of resorptive and formative activity, and the temporal sensitivity of the processes. (elsevierpure.com)
  • Objective: To determine whether BMD in the males continued to decline, the neutral effect of T1D on BMD in females persisted, and whether temporal BMD changes reflected changes in bone turnover markers. (edu.au)
  • Biochemical bone turnover markers. (edu.au)
  • Age- and sex-related changes in bone turnover markers paralleled those in general population studies. (edu.au)
  • This workshop is intended for otolaryngologists interested in the most recent developments in temporal bone surgical techniques. (ahn.org)
  • The surgical treatment of ankylosis of the TMJ consists in removing the ankylotic mass, reconstructing the joint and restoring the patient's functions that have been impaired as a result of the pathological condition. (bvsalud.org)
  • Insulin-like growth factor-1 (IGF-1) plays a critical role in the development of the growing skeleton by establishing both longitudinal and transverse bone accrual. (elsevierpure.com)
  • Further excavations around the female skeleton revealed a second tooth near the top of the leg bone, still within the pelvic cavity. (sciencenewslab.com)
  • The human skeleton is especially affected by the passage of time: bone loss begins as early as the third decade of life, immediately after peak bone mass. (biomedcentral.com)
  • Those who decide to donate their temporal bones may also consider donating the brain tissue related to hearing and balance to allow for even more research possibilities. (masseyeandear.org)
  • Sphenoid wing (SW) en plaque meningioma (ePM) is a subgroup of meningiomas defined by its specific character presenting with a rather thin sheath of soft tumor tissue accompanied by disproportionate and extensive bone hyperostosis. (surgicalneurologyint.com)
  • [ 1 ] ) of bone is a nonheritable disease in which abnormal tissue develops in place of normal bone. (medscape.com)
  • Cancellous bone maintenance is perturbed, and bone undergoing physiologic remodeling is replaced by an abnormal proliferation of fibrous tissue. (medscape.com)
  • In humans, bone is a highly active tissue which undergoes continuous self-regeneration throughout adulthood to maintain structural integrity in a process called bone remodeling. (biomedcentral.com)
  • Bone is a very dynamic and heterogeneous tissue formed by two components which are in close relationship with each other during the bone remodeling process: extracellular matrix (ECM) and bone cells. (biomedcentral.com)
  • Sonographic evaluation of paragangliomas demonstrates a well-defined, heterogeneously hypoechoic mass, with marked internal vascularity on color Doppler (Fig. 2 ). (springeropen.com)
  • Linking individual samples to clinical data using the electronic medical record system (RPDR) as well as databases with molecular data enables sophisticated study of large datasets that enhances the overall quality of the Mass. Eye and Ear investigations. (masseyeandear.org)
  • The availability of substantial patient sample resources also supports new investigations and collaborations, especially between bench and clinical scientists forming another bridge between basic and clinical research at Mass. Eye and Ear. (masseyeandear.org)
  • The external ear is composed of bone and cartilage. (ejao.org)
  • Throughout young adulthood more bone is formed than is resorbed, resulting in an increase in bone mass. (biomedcentral.com)
  • IGF-1 plays an important role in the acquisition and maintenance of bone. (uveitis.org)
  • Glucocorticoids cause bone loss by suppressing bone formation. (uveitis.org)
  • the hearing outcome is no better than the outcomes afforded by bone-conduction devices, and surgery may be associated with recurrence or complications such as meatal stenosis. (ejao.org)
  • The Registry Coordinator will be notified and will make all of the arrangements for the temporal bone removal. (masseyeandear.org)
  • Removal of temporal bones (and brain) does not change the appearance of the head, face, or outer ear. (masseyeandear.org)
  • Schwannoma of the jugular foramen is characteristically a sharply demarcated, contrast-enhancing tumor, typically centered on or based in an enlarged jugular foramen with sharply rounded bone borders and a sclerotic rim. (ajnr.org)
  • Hyperostosis of the greater and lesser wings of the sphenoid bone leading in progressive proptosis is the main characteristics of ePM in this location. (surgicalneurologyint.com)
  • We found that depletion of serum IGF-1 in male iLID mice prior to adulthood (4 weeks) decreased trabecular bone architecture and significantly reduced transverse cortical bone properties (Ct.Ar, Ct.Th) by 16 weeks (adulthood). (elsevierpure.com)
  • Likewise, depletion of serum IGF-1 in iLID males at 8 weeks of age, resulted in significantly reduced transverse cortical bone properties (Ct.Ar, Ct.Th) by 32 weeks (late adulthood), but had no effect on trabecular bone architecture. (elsevierpure.com)
  • Later on, throughout adulthood when the growth period is finished, the amount of resorbed bone equals that which is subsequently formed (remodeling balance). (biomedcentral.com)
  • Physical examination showed a soft 5 cm mass area with no palpable bone in the right occipital. (balkanmedicaljournal.org)
  • Ultrasound is typically utilized early in the diagnostic process, often for initial evaluation of a palpable neck mass. (springeropen.com)
  • Lateral orbitotomy approach for removing hyperostosing en plaque sphenoid wing meningiomas. (surgicalneurologyint.com)
  • A well-defined, echogenic, diffusely heterogenic, 3.15 cm rounded mass with hyperechoic shadow cast spread in it was found dorsal and lateral to the left orbit. (vin.com)
  • The lateral aspect of the left orbital bone was intact and preserved. (vin.com)
  • In contrast, depletion of serum IGF-1 after peak bone acquisition (at 16 weeks) resulted in enhancement of trabecular bone architecture, but no significant changes in cortical bone properties by 32 weeks as compared to controls. (elsevierpure.com)
  • These results indicate that while serum IGF-1 is essential for bone accrual during the postnatal growth phase, depletion of IGF-1 after peak bone acquisition (16 weeks) is compartment-specific and does not have a detrimental effect on cortical bone mass in the older adult mouse. (elsevierpure.com)
  • This is the report of a 6 months old boy presenting with a firm, solitary mass on the temporal region, associated with lysis of local bone. (aku.edu)
  • Osteoblastic cells expressing this mutation have a higher DNA synthesis than normal bone cells. (medscape.com)
  • 1 Preoperative assessment of the temporal bone and inner ear structures is crucial to check the feasibility of implantation and predict the outcome. (ajnr.org)
  • Although informative, mouse models to date have been unable to separate the temporal effects of IGF-1 depletion on skeletal development. (elsevierpure.com)
  • It forms postnatally (starts to develop after 1 year old),[citation needed] as the sternocleidomastoid muscle develops and pulls on the bone. (wikipedia.org)
  • 2 Microgravity has negative effects on physiological systems, including muscle and bone mass loss, which are targeted with exercise and pharmacological countermeasures. (nature.com)
  • The mRNA expression of Cebpb was detected in the clavicle, the zygoma, the temporal muscle and the masseter muscle, respectively. (biomedcentral.com)
  • Ultrasonography of the temporal muscle region was performed. (vin.com)
  • For many Mass. Eye and Ear investigators, the BioBank core is an indispensable resource that greatly enhances the overall quality of their research. (masseyeandear.org)
  • The scientific value of your temporal bone donation is greatly enhanced if it is accompanied by up-to-date medical records. (masseyeandear.org)
  • The medical professionals who remove the temporal bones donate their time or are paid by the laboratory receiving the temporal bones. (masseyeandear.org)
  • Although Cebpb +/- mice did not show the phenotypes above (p = 0.357), a larger mass percentage of temporal muscles over masseter muscles was seen in Cebpb +/- littermates (p = 0.012). (biomedcentral.com)
  • 5 20 45 ] Cushing and Eisenhardt[ 13 ] coined the term of "en plaque" for the first time to differentiate this type of tumor growth from those designated as "en mass" meningiomas. (surgicalneurologyint.com)
  • Osteocytes, which are the most abundant cells in bone, composing 90-95% of all bone cells in an adult. (biomedcentral.com)
  • We will forward a copy of your pledge to one of our collaborating laboratories, which will eventually receive your temporal bones for study. (masseyeandear.org)
  • On imaging study, temporal magnetic resonance imaging showed a partial fluid signal at the left mastoid air cells and abnormal enhancement at the left facial nerve around the genu area ( Fig. 1 ). (ejao.org)