• liver
  • The uncontrolled growth is nonmalignant and does not appear clonal in contrast to the lineage of cells in Langerhans cells histiocytosis ( histiocytosis X ). The spleen, lymph nodes, bone marrow, liver, skin, and membranes that surround the brain and spinal cord are preferential sites of involvement. (medscape.com)
  • Fever
  • The diagnosis is made by the identification of characteristic features of: Fever, hepatomegaly, cytopenias, hypertriglyceridemia or hypofibrogenemia, hemophagocytes in the marrow or other reticuloendothelial system organs, low or absent NK cell activity, a high ferritin level and a high soluble CD25 . (scidoc.org)