• vessel
  • Compared to controls, mice with elevated hematocrit (RBC HIGH ) formed thrombi at a faster rate and had a shortened vessel occlusion time. (bloodjournal.org)
  • Vasculogenesis is the initial establishment of the components of the blood vessel network, or vascular tree. (wikipedia.org)
  • The study of vascular or remodelling in the embryo is widely believed to have been pioneered by Thoma in 1893 when he observed that increases in local blood flow cause widening of the vessel diameter, even going so far as to postulate that blood flow might be responsible for the growth and development of blood vessels. (wikipedia.org)
  • Vasculogenesis occurs prior to vascular remodelling, but is a necessary step in the development of the blood vessel network and has implications on the identification of vessels as either arterial or venous. (wikipedia.org)
  • When vessels are stained with cationic dyes such as Alcian blue stain, transmission electron microscopy shows a small, irregularly shaped layer extending approximately 50-100 nm into the lumen of a blood vessel. (wikipedia.org)
  • Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause. (wikipedia.org)
  • The red blood cells (together with endothelial vessel cells and other cells) are also marked by glycoproteins that define the different blood types. (wikipedia.org)
  • Anemia
  • In refractory anemia (RA) and refractory anemia with ringed sideroblasts (RARS) a discrepancy is observed between the decreased in vitro erythroid colony formation and the normal or increased number of normoblasts in the bone marrow. (biomedsearch.com)
  • Measuring the level of haptoglobin in a patient's blood is ordered whenever a patient exhibits symptoms of anemia, such as pallor, fatigue, or shortness of breath, along with physical signs of hemolysis, such as jaundice or dark-colored urine. (wikipedia.org)
  • The test is also commonly ordered as a hemolytic anemia battery, which also includes a reticulocyte count and a peripheral blood smear. (wikipedia.org)
  • The advisory caution to use blood transfusion only with more severe anemia is in part due to evidence that outcomes are worsened if larger amounts are given. (wikipedia.org)
  • vessels
  • Intravascular injection of diatrizoate also opacifies those vessels in the path of flow of the medium, permitting visualization until the circulating blood dilutes the concentration of the medium. (drugs.com)
  • In this model, a traveling pressure wave would act upon the vasculature via shear stress to rearrange branches into the lowest-energy configuration by widening vessels carrying increased blood flow and rearranging networks upon the initiation of fluid flow. (wikipedia.org)
  • Capillaries can become plugged by the very viscous blood, and the flow of blood through the vessels tends to be extremely sluggish. (wikipedia.org)
  • Vasodilation refers to the widening of blood vessels. (wikipedia.org)
  • The process is the opposite of vasoconstriction, which is the narrowing of blood vessels. (wikipedia.org)
  • When blood vessels dilate, the flow of blood is increased due to a decrease in vascular resistance. (wikipedia.org)
  • Vasodilation is the result of relaxation in smooth muscle surrounding the blood vessels. (wikipedia.org)
  • There are three main intracellular stimuli that can result in the vasodilation of blood vessels. (wikipedia.org)
  • Blood is circulated around the body through blood vessels by the pumping action of the heart. (wikipedia.org)
  • invention
  • The invention relates to methods and devices for correcting the glucose bias in glucose-monitoring products to provide more accurate glucose readings of blood samples. (google.com)
  • clots
  • It may be ordered along with a prothrombin time (PT) test to evaluate hemostasis, the process that the body uses to form blood clots to help stop bleeding. (labcorp.com)
  • Several proteins called coagulation factors are involved in hemostasis and the formation of blood clots. (labcorp.com)
  • heparin is an anticoagulation drug that is given intravenously (IV) or by injection to prevent and to treat blood clots (embolism and thromboembolism). (labcorp.com)
  • Complications may include blood clots, infections, and high blood pressure. (wikipedia.org)
  • transfusions
  • Iron accumulation to toxic and eventually lethal levels can result from repeated blood transfusions (e.g., in β-thalassemia major and sickle cell disease) or from excessive dietary iron uptake because humans are unable to actively eliminate iron from the body. (aspetjournals.org)
  • Transfusions are used for various medical conditions to replace lost components of the blood. (wikipedia.org)
  • Blood transfusions typically use sources of blood: one's own (autologous transfusion), or someone else's (allogeneic or homologous transfusion). (wikipedia.org)
  • A blood donation occurs when a person voluntarily has blood drawn and used for transfusions and/or made into biopharmaceutical medications by a process called fractionation (separation of whole-blood components). (wikipedia.org)
  • Most of the components of blood used for transfusions have a short shelf life, and maintaining a constant supply is a persistent problem. (wikipedia.org)
  • mice
  • This procedure includes a short- in vitro culture, the purification of schizonts and the further generation of synchronized mice infections. (biomedcentral.com)
  • Transfusion
  • Arthropod vectors are thought to be the primary source of infection, although M. haemofelis is also known to be transmitted from queen to kitten and following blood transfusion. (wikipedia.org)
  • M. haemofelis has been transmitted by transfusion and oral administration of infected blood. (wikipedia.org)
  • Blood transfusion is generally the process of receiving blood or blood products into one's circulation intravenously. (wikipedia.org)
  • Before a blood transfusion is given, there are many steps taken to ensure quality of the blood products, compatibility, and safety to the recipient. (wikipedia.org)
  • In 2012, a national blood policy was in place in 70% of countries and 62% of countries had specific legislation that covers the safety and quality of blood transfusion. (wikipedia.org)
  • The World Health Organization (WHO) recommends that all donated blood be tested for transfusion transmissible infections. (wikipedia.org)
  • Leukoreduced blood products are less likely to cause HLA alloimmunization (development of antibodies against specific blood types), febrile non-hemolytic transfusion reaction, cytomegalovirus infection, and platelet-transfusion refractoriness. (wikipedia.org)
  • In poorer countries, established supplies are limited and donors usually give blood when family or friends need a transfusion (directed donation). (wikipedia.org)
  • The screening includes testing for diseases that can be transmitted by a blood transfusion, including HIV and viral hepatitis. (wikipedia.org)
  • An 'allogeneic' (also called 'homologous') donation is when a donor gives blood for storage at a blood bank for transfusion to an unknown recipient. (wikipedia.org)
  • A 'directed' donation is when a person, often a family member, donates blood for transfusion to a specific individual. (wikipedia.org)
  • In this case, a friend or family member of the recipient donates blood to replace the stored blood used in a transfusion, ensuring a consistent supply. (wikipedia.org)
  • This blood is sometimes treated as a blood donation, but may be immediately discarded if it cannot be used for transfusion or further manufacturing. (wikipedia.org)
  • occurs
  • Maximum contrast enhancement frequently occurs after peak blood iodine levels are reached. (drugs.com)
  • This lag suggests that radiographic contrast enhancement is at least in part dependent on the accumulation of iodine within the lesion and outside the blood pool, although the mechanism by which this occurs is not clear. (drugs.com)
  • albumin
  • The blood binding parameters across species and the interaction with human serum albumin were analyzed for deferasirox and its iron complex. (aspetjournals.org)
  • Here we report the blood distribution and plasma protein binding of deferasirox and its iron complex for species used in preclinical safety investigations and healthy humans, as well as characterize the interaction of the two molecules with human serum albumin (HSA). (aspetjournals.org)
  • This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. (wikipedia.org)
  • Albumin is the main protein in plasma, and it functions to regulate the colloidal osmotic pressure of blood. (wikipedia.org)
  • occur
  • peak iodine blood levels occur immediately following rapid injection of the dose. (drugs.com)
  • Low blood sugar may occur in otherwise healthy babies who have not eaten for a few hours. (wikipedia.org)
  • The term "hypoglycemia" is sometimes incorrectly used to refer to idiopathic postprandial syndrome, a controversial condition with similar symptoms that occur following eating but with normal blood sugar levels. (wikipedia.org)
  • These can occur at a blood bank, but they are often set up at a location in the community such as a shopping center, workplace, school, or house of worship. (wikipedia.org)
  • IRBC
  • There was a 5-fold and 12-fold increase in IRBC rolling and adhesion, respectively, when hematocrit increased from 10% to 30%, as a result of changes in shear rate. (ajtmh.org)
  • infection
  • During this stage of infection, M. haemofelis organisms can be identified in a stained blood smear under light microscopy. (wikipedia.org)
  • Other efforts include managing high blood pressure, high blood cholesterol, and infection risk. (wikipedia.org)
  • phlebotomy
  • Immediate phlebotomy is often done, but if the red cell volume is not increased and the plasma volume and total blood volume are decreased, phlebotomy may be harmful. (annals.org)
  • Blood is sometimes collected using similar methods for therapeutic phlebotomy, similar to the ancient practice of bloodletting, which is used to treat conditions such as hereditary hemochromatosis or polycythemia vera. (wikipedia.org)
  • levels
  • Hypoglycemia, also known as low blood sugar, is when blood sugar decreases to below normal levels. (wikipedia.org)
  • Other tests that may be useful in determining the cause include insulin and C peptide levels in the blood. (wikipedia.org)
  • A hypoalbuminemia of less than 2.5 g/dL, that exceeds the hepatic clearance level, that is, protein synthesis in the liver is insufficient to increase the low blood protein levels. (wikipedia.org)
  • Differences in body fat distribution are found to be associated with high blood pressure, high triglyceride, lower high-density lipoprotein (HDL) cholesterol levels and high fasting and post-oral glucose insulin levels The android, or male pattern, fat distribution has been associated with a higher incidence of coronary artery disease, in addition to an increase in resistance to insulin in both obese children and adolescents. (wikipedia.org)
  • Symptoms of leukostasis start when blood levels of leukocytes reach over 100 x 10^9 / L (100,000 / microL). (wikipedia.org)
  • Low levels of EPO (around 10 mU/mL) are constantly secreted sufficient to compensate for normal red blood cell turnover. (wikipedia.org)
  • interaction
  • In vitro interaction with artesunate and the active C. pluviosa fractions was assessed, and mass spectrometry analyses were conducted. (biomedcentral.com)
  • lipids
  • These trials have ranged in duration from 8 weeks to a year, with study outcomes that have included weight, blood lipids and lipoproteins, inflammatory markers, glucose, insulin, blood pressure and body composition. (stanford.edu)
  • patient's
  • This has led to some increased interest in autotransfusion, whereby a patient's blood is salvaged during surgery for continuous reinfusion-or alternatively, is "self-donated" prior to when it will be needed. (wikipedia.org)
  • vascular
  • The entire vascular system can become markedly engorged with blood, and circulation times for blood throughout the body can increase up to twice the normal value. (wikipedia.org)
  • Another main function of the glycocalyx within the vascular endothelium is that it shields the vascular walls from direct exposure to blood flow, while serving as a vascular permeability barrier. (wikipedia.org)
  • autologous
  • Donors can also have blood drawn for their own future use (autologous donation). (wikipedia.org)
  • When a person has blood stored that will be transfused back to the donor at a later date, usually after surgery, that is called an 'autologous' donation. (wikipedia.org)
  • centrifugation
  • Human blood fractioned by centrifugation: Plasma (upper, yellow layer), buffy coat (middle, thin white layer) and erythrocyte layer (bottom, red layer) can be seen. (wikipedia.org)
  • bone
  • Leukostasis is associated with people who suffer from bone and blood disorders and is very common among people suffering from acute myeloid leukemia or chronic myeloid leukemia. (wikipedia.org)
  • glucose
  • and using the percent hematocrit, % Hct c , and either the glucose value, Glu m , or the adjusted glucose value, Glu adj , to adjust for any bias of the biosensor reagent. (google.com)
  • When people feel their blood sugar is low, testing with a glucose monitor is recommended. (wikipedia.org)
  • parameters
  • The blood binding parameters of a drug can be critical for its pharmacokinetics and are needed for a comparison of pharmacokinetics across species. (aspetjournals.org)
  • allogeneic
  • Blood that is used to make medications can be made from allogeneic donations or from donations exclusively used for manufacturing. (wikipedia.org)
  • fluid
  • Localized tissues have multiple ways to increase blood flow, including releasing vasodilators, primarily adenosine, into the local interstitial fluid, which diffuses to capillary beds, provoking local vasodilation. (wikipedia.org)
  • Insects and some mollusks use a fluid called hemolymph instead of blood, the difference being that hemolymph is not contained in a closed circulatory system. (wikipedia.org)
  • About 55% of blood is blood plasma, a fluid that is the blood's liquid medium, which by itself is straw-yellow in color. (wikipedia.org)
  • normal
  • In adults without diabetes, symptoms related to low blood sugar, low blood sugar at the time of symptoms, and improvement when blood sugar is restored to normal confirm the diagnosis. (wikipedia.org)
  • volume
  • Cardiac output (blood flow measured in volume per unit time) is computed by multiplying the heart rate (in beats per minute) and the stroke volume (the volume of blood ejected during ventricular systole). (wikipedia.org)
  • carries
  • Because each unit of blood given carries risks, a trigger level lower than that at 70 to 80 g/L is now usually used as it has been shown to have better patient outcomes. (wikipedia.org)