• Antibodies
  • We evaluated the persistence of bactericidal antibodies through early childhood, following infant immunisation with varying schedules of MenACWY-CRM(197) vaccine. (ox.ac.uk)
  • The basic tests performed when an immunodeficiency is suspected should include a full blood count (including accurate lymphocyte and granulocyte counts) and immunoglobulin levels (the three most important types of antibodies: IgG, IgA and IgM). (wikipedia.org)
  • Tests for T cell function: skin tests for delayed-type hypersensitivity, cell responses to mitogens and allogeneic cells, cytokine production by cells Tests for B cell function: antibodies to routine immunisations and commonly acquired infections, quantification of IgG subclasses Tests for phagocyte function: reduction of nitro blue tetrazolium chloride, assays of chemotaxis, bactericidal activity. (wikipedia.org)
  • antibody
  • CONCLUSIONS: Serogroup-specific bactericidal antibody wane following infant immunisation with MenACWY-CRM(197), most markedly against serogroup A. Best persistence against serogroup C is observed with MenC conjugate vaccine priming and MenACWY-CRM(197) at 12 months, compared to schedules using only MenACWY-CRM(197), with the potential for providing broader protection compared to monovalent MenC vaccines alone. (ox.ac.uk)
  • infection
  • 1922) stated: 'The subsequent history of man 'H' illustrates the lack of resistance to meningococcal infection that accompanies absence of bactericidal power against the meningococcus. (wikipedia.org)
  • The risk of infection does not begin to increase until the neutrophil count decreases to levels below 1,000/mL of blood ( Fig. 157.1 ). (nih.gov)
  • protein
  • Disclosed are novel bactericidal/permeability-increasing (BPI) protein products wherein cysteine residue number 132 or 135 is replaced by another amino acid residue, preferably an alanine or serine residue and/or wherein the leucine residue at position 193 is the carboxy terminal residue. (google.es)
  • 1. A polypeptide analog of bactericidal/permeability-increasing protein or biologically-active fragment thereof wherein a cysteine residue at position 132 or at position 135 is replaced by a different amino acid. (google.es)
  • 5. The polypeptide analog according to claims 1, 2, 3, or 4 comprising, except for the cysteine replacement at either position 132 or 135, from 176 to 199 of the amino terminal residues of bactericidal/permeability- increasing protein. (google.es)
  • 6. The polypeptide analog according to claim 5 comprising the initial 193 amino terminal amino acid residues of bactericidal/permeability- increasing protein. (google.es)
  • 9. The DNA of claim 7 encoding the thirty-one amino acid leader sequence and the first 199 N-terminal residues of bactericidal/permeability- increasing protein and having a stop cόdon immediately following the codon for the isoleucine at position 199. (google.es)
  • 14. A method for producing polypeptide analogs of bactericidal/permeability increasing protein and biologically active fragments thereof comprising growing a host cell according to claim 11 in a suitable culture medium and isolating said analog from said host cell or said culture medium. (google.es)
  • vitro
  • Aims to evaluate the cancer chemopreventive activity ofSorghum bicolor ethanolic extract via in vitro cell culture studies. (healthresearch.ph)
  • Evidence has been presented that H 2 S exhibits pro-inflammatory activity as demonstrated, for example, by its ability to dilate blood vessels in vitro and in vivo [ 7 ]. (wiley.com)
  • dose
  • The dose required should be monitored by blood testing. (wikipedia.org)
  • Adverse effects of gentamicin can range from less severe reactions such as nausea and vomiting to more severe reactions such as: Low blood counts Allergic responses Neuromuscular problems Nerve damage Kidney damage (nephrotoxicity) Ear disorders (ototoxicity) Nephrotoxicity and ototoxicity are thought to be dose related with higher doses causing greater chance of toxicity. (wikipedia.org)
  • antibacterial
  • The main components of gentamicin include members of the gentamicin C complex: gentamicin C1, gentamicin C1a, and gentamicin C2 which compose approximately 80% of gentamicin and have been found to have the highest antibacterial activity. (wikipedia.org)
  • action
  • In the body, taurolidine is metabolized rapidly via the metabolites taurultam and methylol taurinamide, which also have a bactericidal action, to taurine, an endogenous aminosulphonic acid, CO2 and H2O. (wikipedia.org)
  • uptake
  • In preterm infants some IgA may be absorbed through the intestinal epithelium and enter the blood stream though there is very little uptake in full term babies. (wikipedia.org)
  • neutrophils
  • SBP is diagnosed if the fluid contains neutrophils (a type of white blood cell) at greater than 250 cells per mm3 (equals a cell count of 250 x106/L) fluid in the absence of another reason for this (such as inflammation of one of the internal organs or a perforation). (wikipedia.org)
  • levels
  • Azlocillin, cimetidine and probenecid increase blood levels of difloxacin. (wikipedia.org)
  • Factors that increase risk of nephrotoxicity include: Increased age Reduced renal function Pregnancy Hypothyroidism Hepatic dysfunction Volume depletion Metabolic acidosis Sodium depletion Kidney dysfunction is monitored by measuring creatinine in the blood, electrolyte levels, low urine output, foamy urine, and concentrations of other chemicals in the blood. (wikipedia.org)
  • cells
  • Other tests are performed depending on the suspected disorder: Quantification of the different types of mononuclear cells in the blood (i.e. lymphocytes and monocytes): different groups of T lymphocytes (dependent on their cell surface markers, e.g. (wikipedia.org)
  • properties
  • It turned out that Heist's own blood lacked the properties that destroy the particular type of meningococcal bacterium that caused his meningitis. (wikipedia.org)
  • partially
  • Increased hepcidin activity is partially responsible for reduced iron availability seen in anemia of chronic inflammation, such as renal failure. (wikipedia.org)
  • presence
  • Furthermore, administration of NaHS (an H 2 S donor) to mice [ 8 ] provokes an inflammatory reaction as shown by increased tissue myeloperoxidase (MPO) activity (a marker for tissue leucocyte infiltration) and histologically by the presence of accumulated leucocytes extravascularly in the lung. (wiley.com)
  • Optimal function of hepcidin may be predicated upon the adequate presence of vitamin D in the blood. (wikipedia.org)
  • include
  • Notable highlights in the first year of SPRINT-TB's formal existence include identification by Theme 1 of potent activity of bortezomib against a new target M. tuberculosis . (sprinttb.org)
  • high
  • Activity of the alveolar macrophage is relatively high, because they are located at one of the major boundaries between the body and the outside world. (wikipedia.org)
  • treatment
  • The treatment method is carried out by applying the anode to an activity point identified in the specification, applying the cathode to the area to be treated, and applying the operating current. (google.fr)