• antagonist
  • Domperidone, sold under the brand name Motilium among others, is a peripherally selective dopamine D2 receptor antagonist that was developed by Janssen Pharmaceutica and is used as an antiemetic, gastroprokinetic agent, and galactagogue. (wikipedia.org)
  • wherein
  • 2. The method according to claim 1, wherein said pharmacologically active agent is selected from the group consisting of small molecule inhibitors, aptamers, antisense nucleotides, RNA-based inhibitors, siRNAs, antibodies, peptides, and dominant negative proteins. (freepatentsonline.com)
  • 3. The method according to claim 1, wherein said pharmacologically active agent binds to at least a portion of PI3Kβ protein or at least a portion of p110β catalytic subunit of PI3Kβ protein. (freepatentsonline.com)
  • 5 . A device according to claim 2 wherein the therapeutic substance delivered by the device comprises a spermicidal agent. (google.com)
  • 6 . A device according to claim 5 wherein the spermicidal agent is selected from the group consisting of: nonoxynol-9, octoxynol-9, menfegol, benzalkonium chloride and N-docasanol. (google.com)
  • normal
  • Cells with disabling mutations in ERCC1 are more sensitive than normal to particular DNA damaging agents, including ultraviolet (UV) radiation and to chemicals that cause crosslinking between DNA strands. (wikipedia.org)
  • bicalutamide
  • Although bicalutamide does not bind to the ERs, it can increase estrogen levels secondary to blockade of the AR when used as a monotherapy in males, and for this reason, the medication can indirectly activate the ERs to a degree and hence have some indirect estrogenic effects in men. (wikipedia.org)
  • symptoms
  • In Italy it is used in the treatment of gastroesophageal reflux disease and in Canada, the drug is indicated in upper gastrointestinal motility disorders and to prevent gastrointestinal symptoms associated with the use of dopamine agonist antiparkinsonian agents. (wikipedia.org)
  • production
  • Although fetal production is impaired, it causes no prenatal effects, as the placental connection allows maternal blood to "dialyze" the fetus and maintain both electrolyte balance and blood volume. (wikipedia.org)
  • results
  • Domperidone, by acting as an anti-dopaminergic agent, results in increased prolactin secretion, and thus promotes lactation (that is, it is a galactogogue). (wikipedia.org)
  • body
  • It is rolled onto an erect penis before intercourse and blocks ejaculated semen from entering the body of a sexual partner. (wikipedia.org)
  • target
  • Even though 4x1 HD-tDCS is simple to perform, correct electrode positioning is important in order to accurately stimulate target cortical regions and exert its neuromodulatory effects. (jove.com)