Loading...
  • uveitis
  • Cytomegalovirus Anterior Uveitis: Clinical Characteristics and Long-term Outcomes in a French Series. (bioportfolio.com)
  • He is the recipient of many awards including the Research to Prevent Blindness Olga Keith Weiss Scholar Award, Research to Prevent Blindness Lew R. Wasserman Merit Award, Research to Prevent Blindness Senior Scientific Investigator, American Academy of Ophthalmology Senior Achievement Award, Clinical Uveitis Research Award from the German Uveitis Patient Interest Group, EyeCare America, Lifetime Volunteer Physician Award, and European Uveitis Patient Interest Association (EUPIA) Uveitis Award. (wikipedia.org)
  • onset
  • Experiencing the vision of floaters, flashes, blurred vision and loss of side vision in just one of the eyes is an early indication of the onset of Retinitis. (wikipedia.org)
  • The incidence of new-onset CMV retinitis in the non-affected eye was calculated, and baseline risk factors for fellow eye involvement calculated using a Cox proportional hazards model. (arvojournals.org)
  • patients
  • Of these CMV patients, 75-85% will develop retinitis. (clinicaltrials.gov)
  • OBJECTIVES: To analyze the association of newly identified IFNL3/4 variant rs368234815 with susceptibility to CMV-associated retinitis in a cohort of HIV-infected patients. (uzh.ch)
  • RESULTS: A total of 40 individuals among 1134 patients at risk developed CMV retinitis. (uzh.ch)
  • Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil. (bioportfolio.com)
  • The influence of cytomegalovirus (CMV) on the progression of chronic periodontitis in HIV patients is poorly investigated. (bioportfolio.com)
  • Impact of Cytomegalovirus Infection on the Outcome of Patients With Cirrhosis: A Preliminary Study. (bioportfolio.com)
  • The aims of this study were to evaluate whether cytomegalovirus (CMV) infection is associated with hepatocellular carcinoma (HCC) and liver-related mortality in cirrhotic patients. (bioportfolio.com)
  • To compare two treatment strategies in patients with relapsed or nonresponsive CMV retinitis: (1) continuing the same anti-CMV drug or (2) switching to the alternate drug. (clinicaltrials.gov)
  • Although most retinitis responds well to initial therapy with systemically administered drugs, given enough time, nearly all patients will suffer a relapse of the retinitis. (clinicaltrials.gov)
  • All 39 eyes of the 26 patients presented healing of retinitis as shown by clinical improvement evaluated by indirect binocular ophthalmoscopy and retinography. (scielo.br)
  • Retinitis healed within a period of 4 to 6 weeks in all patients, with clinical regression signs from the third week on. (scielo.br)
  • None of the patients developed CMV retinitis in the contralateral eye. (scielo.br)
  • The increasing number of organ and medulla transplants and an increase in the use of immunosuppressants were associated with the presence of pneumonitis, colitis, hepatitis, encephalitis, retinitis and other diseases due to CMV in these patients. (scielo.br)
  • Integration of CMV retinitis into HIV programs is therefore feasible, but dependent on systematic screening of at-risk patients and securing access to affordable oral valganciclovir, the authors argue. (doctorswithoutborders.org)
  • Additionally, devices such as low-vision magnifiers can be used to aid vision in patients suffering from despaired vision due to retinitis. (wikipedia.org)
  • A study including patients with Retinitis was conducted by using gene therapy. (wikipedia.org)
  • In this prospective cohort study, 25 consecutive HIV-infected patients with unilateral CMV retinitis received repeated dilated fundus examinations according to a standardized schedule for 12 months. (arvojournals.org)
  • incidence
  • The association of CMV-associated retinitis with rs368234815 was assessed by cumulative incidence curves and multivariate Cox regression models, using the estimated date of HIV infection as a starting point, with censoring at death and/or lost follow-up. (uzh.ch)
  • The investigators aim is to determine the incidence of cytomegalovirus resistance to antivirals in a cohort study. (bioportfolio.com)
  • The incidence of fellow eye development of CMV retinitis during the first year at risk was 0.03 per person-month (95%CI 0.01 to 0.07). (arvojournals.org)
  • Ocular involvement is a frequent manifestation of the HIV infection, resulting in a high incidence of blindness within this patient population. (springer.com)
  • treatment
  • To determine the best therapeutic regimen, using currently approved drugs, for treatment of relapsed cytomegalovirus (CMV) retinitis. (clinicaltrials.gov)
  • We can diagnose CMV retinitis fairly easily and reliably in less than two minutes, and there is an effective, practical treatment," said one of the authors, Dr. David Wilson, former Doctors Without Borders/ Médecins Sans Frontières (MSF) medical coordinator in Thailand. (doctorswithoutborders.org)
  • CMV retinitis is not mentioned in the current and pending WHO guidelines for HIV treatment in resource-poor settings. (doctorswithoutborders.org)
  • acute
  • NGOs have been proposed a discounted price from Roche of € 1,281 (US$ 1,899) for a four-month course of therapy, but this offer remains expensive and excludes many countries where the CMV retinitis problem is most acute. (doctorswithoutborders.org)
  • treat
  • Current research on Retinitis includes studying stem cells, medications, gene therapies, and transplants to help treat/cure this condition. (wikipedia.org)
  • Recent research has shown that AAV can successfully restore color vision to treat color blindness in adult monkeys. (wikipedia.org)
  • phase
  • This phase I trial studies the side effects and the best dose of vaccine therapy in healthy volunteers with or without previous exposure to cytomegalovirus. (bioportfolio.com)
  • gene
  • Retinitis is controlled by a single gene which can be inherited via an autosomal dominant, autosomal recessive, or X-linked gene. (wikipedia.org)