• It is also used for long-term maintenance or prophylaxis, for example 200 mg-400 mg daily for HIV-infected patients, 400 mg daily for patients suffering from chronic pulmonary aspergillosis, or 100 mg per day for more than one year for the treatment of paracoccidioidomycosis [ 1 ]. (ecancer.org)
  • Paracoccidioidomycosis, formerly known as South American blastomycosis and Lutz-Splendore-Almeida disease, is a fungal infection endemic to South and Central America, most notably Brazil, Argentina, Colombia, and Venezuela (see the image below). (medscape.com)
  • Blastomycosis is endemic to the eastern United States and Canada, especially the Ohio and Mississippi River valleys, the Great Lakes, and the St. Lawrence River valley. (wikipedia.org)
  • Paracoccidioidomycosis is a fungal infection endemic to South and Central America, most commonly Brazil, Argentina, Colombia, and Venezuela (see the image below). (medscape.com)
  • Bellissimo-Rodrigues F, Bollela VR, Da Fonseca BA, Martinez R. Endemic paracoccidioidomycosis: relationship between clinical presentation and patients' demographic features external icon . (cdc.gov)
  • Paracoccidioidomycosis can be treated with antifungal medicines such as itraconazole and amphotericin B. 7 Another medicine often used to treat paracoccidioidomycosis is trimethoprim/sulfamethoxazole (TMP/SMX), which is also known as co-trimoxazole and by several different brand names, including Bactrim, Septra, and Cotrim. (cdc.gov)
  • Paracoccidioidomycosis is caused by inhaling spores of the fungus, which grow in soil. (msdmanuals.com)
  • It's difficult to avoid breathing in the fungus that causes paracoccidioidomycosis in areas where it's common in the environment. (cdc.gov)
  • The exact time between inhaling the fungus and getting paracoccidioidomycosis is not known, but scientists believe that many people are exposed to the fungus as children in areas where it's common in the environment. (cdc.gov)
  • Because the symptoms are variable and nonspecific, blastomycosis is often not even considered in differential diagnosis until antibacterial treatment has failed, unless there are known risk factors or skin lesions. (wikipedia.org)
  • The diagnosis of paracoccidioidomycosis is most commonly made by visualization of the yeast cells in tissue, wet preparations (eg, sputum), or superficial scrapings (eg, skin lesions). (medscape.com)
  • Diagnosis of paracoccidioidomycosis by dot immunobinding assay for antibody detection using the purified and specific antigen gp43. (atlasclinicalfungi.org)
  • Blastomycosis, also known as Gilchrist's disease, is a fungal infection, typically of the lungs, which can spread to brain, stomach, intestine and skin, where it appears as crusting purplish warty plaques with a roundish bumpy edge and central depression. (wikipedia.org)
  • less than 50% of healthy people with blastomycosis have symptoms, while immunocompromised patients are especially likely to have the disease spread beyond the lungs to other organs like the skin and bones. (wikipedia.org)
  • Blastomycosis in the lungs may present a variety of symptoms, or no symptoms at all. (wikipedia.org)
  • 1 , 2 For people who develop symptoms, paracoccidioidomycosis usually affects the lungs and skin. (cdc.gov)
  • 3 , 4 In adults, paracoccidioidomycosis usually affects the lungs and causes lesions in the mouth and throat. (cdc.gov)
  • Other extensive manifestations of disseminated blastomycosis are genitourinary tract https://bestlatinabrides.net/reviews/datelatinamerica-review/ infections, solid waste arthritis, CNS infection, and osteomyelitis. (britishflorida.com)
  • Although blastomycosis is especially dangerous for those with weak immune systems, most people diagnosed with blastomycosis have healthy immune systems. (wikipedia.org)
  • Paracoccidioidomycosis typically infects people with a healthy immune system. (msdmanuals.com)
  • Paracoccidioidomycosis can occur in healthy people and people with weakened immune systems. (cdc.gov)
  • Blastomycosis also affects a broad range of non-human mammals, and dogs in particular are an order of magnitude more likely to contract the disease than humans. (wikipedia.org)
  • In patients with active paracoccidioidomycosis, chest radiography reveals interstitial infiltrates (in 64% of cases) or mixed lesions with linear and nodular infiltrates. (medscape.com)
  • Scientists estimate that less than 5% of patients with paracoccidioidomycosis die from the disease. (cdc.gov)
  • Morejon KM, Machado AA, Martinez R. Paracoccidioidomycosis in patients infected with and not infected with human immunodeficiency virus: a case-control study external icon . (cdc.gov)
  • Blastomycosis has existed for millions of years but was first described by Thomas Caspar Gilchrist in 1894. (wikipedia.org)