• infect
  • If a patient becomes immunosuppressed, especially during AIDS, reactivated JC virus can infect lymphocytes, be carried to the brain, infect oligodendroglia glial cells, and produce a demyelinating disease called progressive multifocal leukoencephalopathy . (med-life.net)
  • The Polyomavirus family includes two members, BK virus (BKV) and JC virus (JCV), that naturally infect humans. (ebscohost.com)
  • kidney
  • The JC virus localizes to and remains latent in the kidney, from whence it occasionally may reactivate. (med-life.net)
  • Patients undergoing therapy to suppress the immune system are at risk for hemorrhagic cystitis due to either the direct effects of chemotherapy or activation of dormant viruses in the kidney, ureter, or bladder. (wikipedia.org)