• synthesis
  • Many of the synthesis pathways for methanogenic cofactors were worked out biochemically in this organism, as were several other archaeal-specific metabolic pathways. (wikipedia.org)
  • Many novel metabolic pathways have been worked out in M. jannaschii, including the pathways for synthesis of many methanogenic cofactors, riboflavin, and novel amino acid synthesis pathways. (wikipedia.org)
  • The efficient asymmetric synthesis of new chiral gamma-chloro-alpha,beta-diamino acid derivatives via highly diastereoselective Mannich-type reactions of N-(diphenylmethylene) glycine esters across. (ugent.be)
  • These susceptibility data are given on a few medically significant bacteria: Staphylococcus aureus - 0.125 - >100 μg/ml Methicillin resistant Staphylococcus aureus (MRSA) - 15.6 - >1000 μg/ml Streptococcus pneumoniae 0.39 μg/ml Like other beta-lactam antibiotics, meticillin acts by inhibiting the synthesis of bacterial cell walls. (wikipedia.org)
  • This is why NutraBio Post Recovery contains key recovery enhancing, muscle building ingredients such as glutamine, creatine, beta alanine, betaine, and an unparalleled 8g dose of BCAAs, to ensure optimal protein synthesis, decrease muscle soreness, and ultimately have you ready to tackle your next training session with full intensity. (lockoutforums.com)
  • Beta-alanine helps boost the synthesis of carnosine which helps prevent the drop in pH levels. (cardiostrong.co)
  • His other work in this field includes elucidation of the mechanism of action of corticotropin (ACTH) in regulating steroid hormone synthesis in the adrenal cortex, regulation of adrenal steroidogenic capacity in disease states, and the cloning and elucidation of the structure of ACTH receptor. (wikipedia.org)
  • PBPs
  • PBP2a works in a similar manner to other PBPs, but it binds β-lactams with very low affinity, meaning they do not compete efficiently with the natural substrate of the enzyme and will not inhibit cell wall biosynthesis. (wikipedia.org)
  • In addition to traditional beta-lactams, other classes of molecules (non-beta-lactams) that inhibit PBPs are now emerging, opening new perspectives for tackling the resistance problem while taking advantage of these valuable targets, for which a wealth of structural and functional knowledge has been accumulated. (ac.be)
  • In this paper, we present a general background on the GTs and TPs/PBPs, a survey of recent issues of bacterial resistance and a review of recent works describing new inhibitors of these enzymes. (ac.be)
  • The structural similarity between β-lactam antibiotics and d-alanyl-d-alanine facilitates their binding to the active site of PBPs. (wikipedia.org)
  • aerobic
  • Research studies support that using beta-alanine helps regulate pH, thereby helping increase aerobic endurance, delay muscle fatigue, and increase muscle mass, strength and output. (cardiostrong.co)
  • enzymes
  • Meticillin is insensitive to beta-lactamase (also known as penicillinase) enzymes secreted by many penicillin-resistant bacteria. (wikipedia.org)
  • These enzymes are involved in detoxification, metabolism, and biosynthesis of energetic macromolecules that are important for different essential functions," says lead investigator Dr. Mark A. D'Andrea. (elsevier.com)
  • intensity
  • Some research shows that taking beta-alanine modestly improves some measures of physical performance, especially during high-intensity exercise and strength training . (webmd.com)
  • synergistically
  • This 4-way blend works synergistically to stimulate an intense cascade of adrenaline, dopamine and acetylcholine levels in the brain, which works in harmony by increasing mood, stimulating more energy availability, mitigating sedation and enhances complete cognitive performance. (nutritionwarehouse.com.au)
  • Using the latest advances in supplement research, Post Recovery combines ingredients known to work synergistically to reduce exercise-induced muscle damage, support rapid recovery, and promote muscle strength and growth. (lockoutforums.com)
  • strain
  • The final strain produced 3HP at a titer of 13.7 +/- 0.3 g L-1 with a 0.14 +/- 0.0 C-mol C-mol(-1) yield on glucose in 80 h in controlled fed-batch fermentation in mineral medium at pH 5, and this work therefore lays the basis for developing a process for biological 3HP production. (chalmers.se)
  • performance
  • Beta-alanine is used for improving athletic performance and exercise capacity, building lean muscle mass, and improving physical functioning in the elderly. (webmd.com)
  • Beta-alanine supplements might also improve physical performance and delay muscle fatigue in older adults. (webmd.com)
  • effective
  • Early research suggests that taking beta-alanine is less effective than the drug veralipride at reducing hot flashes in menopausal women. (webmd.com)
  • vancomycin
  • in particular, in cases of relapse or where the infection is unresponsive to metronidazole treatment (for this indication, vancomycin is given orally, rather than by its typical intravenous route) For treatment of infections caused by Gram-positive microorganisms in patients with serious allergies to beta-lactam antimicrobials. (wikipedia.org)
  • high
  • With the objective of developing Saccharolnyces cerevisiae as an efficient cell factory for high-level production of 3HP, we identified the beta-alanine biosynthetic route as the most economically attractive according to the metabolic modeling. (chalmers.se)
  • results
  • Mutagenesis of this residue to alanine (D99A) or asparagine (D99N) results in a loss in activity at pH 7 of 3000-fold and 27-fold, respectively, implicating Asp-99 as important for enzymatic activity. (wikipedia.org)
  • safety
  • There is not enough reliable information about the safety of taking beta-alanine if you are pregnant or breast -feeding. (webmd.com)