Histological assessment of 17 cases confirmed adequate bone replacement of the Triosite although some areas of tricalcium phosphate remained visible. (openorthopaedicsjournal.com)
A PMMA-embedded tricalcium phosphate scaffold was used with both a closed and an open porosity structure and bone ingrowths as a representative system of three known materials. (bvsalud.org)
Composites2
Effect of high aspect ratio filler on dielectric properties of polymer composites: a study on barium titanate fibers and graphene platelets. (speedmixer.uk)
Nowadays, in order to avoid limits affecting long-term durability of resin composites, dental materials companies are focusing their attention on the improvement of the mechanical and biological properties of filler. (hindawi.com)
Substitute12
Stravinskas M, Nilsson M, Vitkauskiene A, Tarasevicius S, Lidgren L. Vancomycin elution from a biphasic ceramic bone substitute. (boneandjoint.org.uk)
An injectable ceramic bone substitute, with hydroxyapatite in a calcium sulphate matrix, containing 66 mg of vancomycin per millilitre, was inserted to augment the fixation. (boneandjoint.org.uk)
This is the first long-term pharmacokinetic study that reports vancomycin release from a biphasic injectable ceramic bone substitute. (boneandjoint.org.uk)
The plain ceramic bone substitute has been proven to regenerate bone but should also be useful in preventing bone infection. (boneandjoint.org.uk)
The aim of this study was to investigate a new commercially available bone substitute that elutes antibiotics, combining an initial high local release with a sustainable antibiotic level for a sufficiently long time to eradicate or prevent infection effectively. (boneandjoint.org.uk)
Autograft and allograft have both been associated with complications and the use of bone substitute wedges has been advocated to improve the outcome. (openorthopaedicsjournal.com)
This technique creates a wedge shaped defect in the bone, which can be managed either by leaving to heal or grafting with bone, bone substitute or other synthetic materials. (openorthopaedicsjournal.com)
Bone substitute wedges often appear as well delineated areas on radiographs several years following the osteotomy and this failure of full incorporation raises the question of the mechanical strength of the tibia and whether it will be suitable to undergo conversion to a total knee replacement when required. (openorthopaedicsjournal.com)
If compared with other types of bioceramics (such as alumina, zirconia, calcium silicates, calcium sulfate, etc.), the main feature and superiority of CaPO 4 is based on their chemical similarity to the composition of calcified tissues of mammals (bones, teeth, and deer antlers) and the need for versatile and risk-free bone substitute biomaterials immediately available without the constraint of bone grafts. (encyclopedia.pub)
Such grafts can be of biological origin or be composed of a synthetic bone substitute. (bvsalud.org)
Bioactive glass appears to be a suitable bone substitute not only for successful control of infection and defect filling but also for bone healing in cases of infected non-union. (copernicus.org)
Grafts4
A strong interest was raised in studying ceramics as potential bone grafts due to their biomechanical properties. (encyclopedia.pub)
Current biomedical applications of CaPO 4 -based bioceramics include artificial bone grafts, bone augmentations, maxillofacial reconstruction, spinal fusion, and periodontal disease repairs, as well as bone fillers after tumor surgery. (encyclopedia.pub)
In large bone lesions, such as severe bone fractures, bone cancer or other diseases, bone grafts substituting the lost bone might be necessary. (bvsalud.org)
Patients with chronic osteomyelitis and infected non-union who received either bioactive glass or autologous bone grafts between 2013 and 2017 were analyzed retrospectively. (copernicus.org)
Biphasic3
This study investigated the clinical, radiological and histological outcomes of using biphasic calcium phosphate ceramic (Triosite) wedges in opening wedge high tibial osteotomy and determined whether the presence of the graft would compromise the satisfactory conversion to a total knee replacement. (openorthopaedicsjournal.com)
Biphasic calcium phosphate ceramic wedges (Triosite) can be reliably used in opening wedge high tibial osteotomy with a low incidence of complications and satisfactory conversion to total knee arthroplasty. (openorthopaedicsjournal.com)
Tissue engineering and regenerative medicine can provide a novel treatment regime based on the use of synthetic biomaterials, which may be constructed into three-dimensional implants and combined with biologics (such as cells and/or bioactive molecules). (edu.au)
made of fully synthetic bone that correspond to the calcium phosphate component of natural bone in chemical composition and crystalline structure. (medicalexpo.com)
Graft substitutes2
The demand for bone graft substitutes is estimated to increase by 30 percent from 2013 to 2020. (edu.au)
This evaluation also considers the role SLIHI could play for the design of cell-free, drug-free osteoinductive bone graft substitutes. (bvsalud.org)
For this reason, in the recent five years hydroxyapatite particles and whiskers have been added as novel bioactive and biocompatible reinforcing filler in dental restorations. (hindawi.com)
We compared the outcome of using bioactive glass (BAG) versus autologous bone graft (AB) in patients with infected non-union. (copernicus.org)
In our study, bioactive glass was neither superior nor inferior to autologous bone graft with regard to the primary and secondary endpoints. (copernicus.org)
Regeneration4
Our work aims to develop optimal tissue engineered constructs for the repair and regeneration of different types of musculoskeletal tissues, including bone, cartilage and tendon. (edu.au)
The recognition and importance of immune cells during bone regeneration, including around bone biomaterials, has led to the development of an entire field termed "osteoimmunology," which focuses on the connection and interplay between the skeletal system and immune cells. (bvsalud.org)
First, the various immune cell types involved in bone biomaterial integration are discussed, including the prominent role of osteal macrophages (OsteoMacs) during bone regeneration. (bvsalud.org)
These findings highlight and recognize the importance of the immune system and osteoimmunology, leading to a shift in the traditional models used to understand and evaluate biomaterials for bone regeneration. (bvsalud.org)
Ceramic1
In addition, hydroxyapatite whiskers (wHA) have been considered the best option as reinforcing filler in comparison with other whiskers based on carbon, ceramic, glass, metal, and polymer due to the absence of cytotoxicity effects [ 12 , 13 ]. (hindawi.com)
Hydroxyapatite3
Data obtained show better interfacial interaction with filler/matrix until 20 wt% of hydroxyapatite whiskers partially replaced silica particles filler. (hindawi.com)
In fact, it was shown that the incorporation of hydroxyapatite with whiskers morphology can provide larger load transfer and favor toughening mechanisms, thus, increasing flexural modulus and fracture toughness of resins in comparison with conventional silica based fillers [ 6 - 11 ]. (hindawi.com)
This information is of primary interest in order to achieve a final consistency and specific formulation of hydroxyapatite whiskers mixed with silica particles filler in resin composite. (hindawi.com)
Defects2
Synthes' other business segments are the production of surgical power tools and biomaterials used to fill bone defects. (wikipedia.org)
The gold standard for filling defects is the autologous bone graft. (copernicus.org)
Favor1
One of the major properties of most types of CaPO 4 is their osteoconductivity, an ability to favor bone healing and to bind firmly to bone tissues. (encyclopedia.pub)
Implants2
It is the world's largest maker of implants to mend bone fractures, and also produces surgical power tools and advanced biomaterials. (wikipedia.org)
Synchrotron nanoCT imaging has great potential to contribute to further the understanding of integration of implants into bone tissue by imaging the spatial interaction between bone tissue and implant, and by accessing the interface between implant material and bone tissue. (bvsalud.org)
Complications2
Secondary endpoints were bone healing, functional outcome, and occurrence of complications. (copernicus.org)
Patients with multidrug-resistant pathogens had a significantly higher rate of incomplete bone healing ( p =0 .033) and a 3-fold higher risk of complications in both groups. (copernicus.org)
Tissue3
Our tissue engineering research focuses on repairing diseased or damaged tissues, incorporating the areas of biomaterials, stem cells, computer modelling and molecular biology. (edu.au)
use of glass ampoules1 while the high contrast of blue pre-colored cement provides optimal visualization against bone and soft tissue. (medicalexpo.com)
This can cause an increase in bone loss, trauma to the surrounding tissue, and longer surgical time. (afpm.org.my)
Properties1
This review article serves as a guide highlighting advancements made in the field of osteoimmunology emphasizing the role of the osteoimmunomodulatory properties of biomaterials and their impact on osteoinduction. (bvsalud.org)
Reconstruction1
The goals of osteomyelitis therapy are successful control of infection and reconstruction of the bone. (copernicus.org)
Occurrence1
This article describes the development of a partially degradable metal bone pin, proposed to minimize the occurrence of bone refracture by avoiding the creation of holes in the bone after pin removal procedure. (afpm.org.my)
Clinical1
In 2009 the U.S. attorney in Philadelphia accused the company of illegally promoting a bone void filler for unapproved uses, running unauthorized clinical trials, and failing to properly report deaths and adverse events related to the product. (wikipedia.org)
Materials1
However, in order to be accepted by the living body without any unwanted side effects, all implantable items must be prepared from a special class of tolerable materials, called biomedical materials or biomaterials, in short. (encyclopedia.pub)
A spiral defect formation was identified as the cause for the ductile fracture of the weld joint. (afpm.org.my)
High1
Opening wedge high tibial osteotomy often requires bone grafting to improve the union rate and avoid instability at the osteotomy site. (openorthopaedicsjournal.com)
Development1
Thus, working on filler packing, optimization of filler content, and development of a new innovative fillers is needed. (hindawi.com)
Concentrations1
Problems include low antibiotic concentrations due to inadequate perfusion of the bone and the surrounding soft tissues (van Vugt et al. (copernicus.org)
Fill1
It is also used to reshape lost bone and fill gaps in bones . (medicalexpo.com)
Types2
Similarly, all types of solid biomaterials are also divided into the same groups: biometals, biopolymers, bioceramics, and biocomposites. (encyclopedia.pub)
Most studies have focused on the "osteogenic" capacity of various types of bone biomaterials, and much less focus has been placed on immune cells despite being the first cell type in contact with implantable devices. (bvsalud.org)
Product1
Between 2002 and 2004, Synthes attempted to promote new uses for a product called Norian XR, a calcium phosphate bone void filler mixed with barium sulfate. (wikipedia.org)
Soft1
Heterotopic ossification (HO) is a condition triggered by an injury leading to the formation of mature lamellar bone in extraskeletal soft tissues. (bvsalud.org)
Https1
Dorozhkin, Sergey V.. "Biomedical Applications of Calcium Orthophosphate (CaPO 4 )-Based Bioceramics" Encyclopedia , https://encyclopedia.pub/entry/46492 (accessed December 02, 2023). (encyclopedia.pub)
Increase1
Unfortunately, this has also caused a drastic increase in musculoskeletal conditions impacting bones, joints and tendons, which impose annual costs of $5.7 billion on the Australian healthcare system. (edu.au)
Made1
The pin was made by friction welding and composed of two parts: the degradable part that remains in the bone and the nondegradable part that will be removed as usual. (afpm.org.my)