• Their concentration increases specifically and differently during various pathological states, including cardiovascular diseases ( table 1 ) [ 8 ]. (ersjournals.com)
  • Mitochondrial dysfunction has been proven to play a critical role in the pathogenesis of cardiovascular diseases. (frontiersin.org)
  • We hope this review will provide perspectives on mitochondrial-targeted therapeutics in cardiovascular diseases. (frontiersin.org)
  • The abnormal morphology and dysfunction of mitochondria have been proven as the principal mechanisms in the pathogenesis of cardiovascular diseases, such as heart failure, myocardial infarction, atherosclerosis, and hypertension ( 4 - 6 ). (frontiersin.org)
  • So mitochondria-targeted therapy is suggested to be a potential treatment strategy for cardiovascular diseases. (frontiersin.org)
  • However, clinical trials of these agents for cardiovascular diseases were hardly approved to carry out, even less to evaluate their clinical effectiveness and safety. (frontiersin.org)
  • Therefore, patients with cardiovascular diseases would fail to achieve the desired outcomes by using these mitochondrial-targeted drugs ( 5 ). (frontiersin.org)
  • However, the great challenge today is to delay the onset and severity of non-AIDS-defining comorbidities, which appear much earlier in HIV-infected individuals [ 5 ] and include cardiovascular diseases, diabetes mellitus , kidney, liver, and bone alterations, and neoplasia [ 4 - 8 ]. (hindawi.com)
  • The comprehensive list comprised an array of well-known threats including non-communicable diseases such as cancer, type-2-diabetes, cardiovascular disease, and stroke, as well as emerging threats such as antimicrobial resistance. (news-medical.net)
  • Raman spectroscopy has slipped into biomedical science proving its utility in medical diagnostics for diseases as diverse as cancer, cardiovascular disease and bacterial infections. (news-medical.net)
  • Although obesity is a primary risk factor for the development of a variety of cardiometabolic diseases, this demonstrates that there must be an internal genetic and physiological environment characteristically unique in ethnic groups. (lifebeatnewspaper.com)
  • As the human lifespan increases, the incidence of such diseases-including neurodegenerative disorders like Alzheimer's and Parkinson's, cardiovascular conditions, metabolic diseases like diabetes, musculoskeletal conditions like osteoporosis and osteoarthritis, and immune system disorders-also rises. (decodeage.com)
  • With life expectancy significantly increasing in recent decades, these diseases have become major public health issues. (decodeage.com)
  • However, recent research has shown an increasing interest in exosomes as a source of biomarkers for age-related neurodegenerative diseases. (decodeage.com)
  • The search for new active drugs that can alleviate or cure different diseases is a constant challenge to researchers in the biological area and to the pharmaceutical industry. (scielo.br)
  • Obesity is defined as an expansion of white adipose (WAT) tissue that is associated with low grade inflammation which possibly contributes to the development of health complications such as diabetes, liver pathologies, dyslipidemia, cardiovascular diseases as well as some cancers [ 2 - 4 ]. (springer.com)
  • Immune dysregulation has been identified as a critical cause of the most common types of cardiovascular diseases (CVDs). (biomedcentral.com)
  • Many types of cardiovascular diseases (CVDs) are associated with complex immune responses that can significantly contribute to their progression and remission. (biomedcentral.com)
  • We have successfully integrated LC-MS methods for the targeted and untargeted analysis of lipids, polar metabolites, and exposome compounds (LIMeX) for diverse sample types and used them for studies focused on cardiovascular diseases, type 2 diabetes, lipogenesis, circadian rhythms, and drug adherence. (cas.cz)
  • Systemic Lupus Erythematous (SLE) and Progressive Systemic Sclerosis (PSS) are two such diseases that often come packing with this frigid digit phenomena. (doctorschar.com)
  • This review describes, analyzes and compares the effects of different types of diets in reducing the onset of typical Western countries non-communicable diseases (NCDs) (cardiovascular diseases, tumors, chronic respiratory diseases, diabetes, etc.), thus increasing the average lifespan. (iospress.com)
  • Cardiovascular diseases (CVDs) account for most NCDs deaths (17.7 million people annually), followed by cancers (8.8 million), respiratory diseases (3.9 million) and diabetes (1.6 million) [ 1 ]. (iospress.com)
  • Dr. Lee's research is focused mainly on the understanding of the pathological mechanism(s) underlying the selective neurodegeneration in Alzheimer disease (AD) and other neurodegenerative diseases. (utsa.edu)
  • Cardiovascular diseases are one of the leading causes of death globally and the most common pathological process is atherosclerosis. (openbiomedicalengineeringjournal.com)
  • Cardiovascular Diseases (CVDs) are the most common reason for death and they are considered to be one of the most important problems related to human health worldwide. (openbiomedicalengineeringjournal.com)
  • It can be enforced to identify phenomena related to the ANS in healthy subjects and patients with certain diseases, such as diabetes mellitus 8, 9 , chronic obstructive pulmonary disorder (COPD) 10 , epilepsy 11,12 and those referred to as "dynamical diseases 13 . (bvsalud.org)
  • Importance of study: With its population-based recruitment, repeated follow-ups with the collection of biological material throughout childhood and into adolescence, little loss, more than 6000 variables, a European cooperation and the development of a common database of more than 30 000 children, there is an excellent opportunity to cutting-edge research aimed at preventing pulmonary and allergic diseases and to reduce the burden on those already affected. (gu.se)
  • The US Centers for Disease Control and Prevention (CDC), the Lancet Commission on Hypertension Group, Resolve to Save Lives (RTSL), and the World Hypertension League (WHL) share a collective goal of expanding the evidence base on hypertension, sodium, and trans fatty acid reduction strategies as a critical pathway to preventing and managing cardiovascular diseases. (cdc.gov)
  • As a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, this protein catalyzes the cis-trans isomerization of proline imidic peptide bonds, which allows it to regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. (wikipedia.org)
  • Apoptosis occurs in many physiological and pathological processes. (wikipedia.org)
  • Mitochondria not only serve as power plants in cells but also act as crucial regulators in many biological processes, including reactive oxygen species (ROS) signaling, redox balance, calcium homeostasis, protein quality control, and programmed cell death ( 3 , 4 ). (frontiersin.org)
  • If a chemical compound targeting one of these hubs is used, it can not only modify the anticipated biological pathways but also change other unexpected mitochondrial processes ( 5 ). (frontiersin.org)
  • Cells and tissues play a fundamental role in advancing our understanding of biological processes. (filosofia-internet.net)
  • In all types of CVDs, inflammation has been further documented as one of the critical events in the initiation and spread of the pathological processes. (biomedcentral.com)
  • Mammalian circadian rhythms can be observed from the genetic level to the tissue level, and even to the macroscopic level, affecting behavior, biochemical and physiological processes. (frontiersin.org)
  • Enzymes are biological molecules produced by living entities for carrying out biological processes. (preprints.org)
  • access to health-care services, and pact of SEP on many pathological The pervasive nature of the social chemical and physical exposures processes means that it is consid- structures that make up the outer (e.g. occupational exposures, pollu- ered one of the main determinants of layer of our environments means that tion). (who.int)
  • Notably, the innate and adaptive immune responses under physiological conditions are typically regulated with high sensitivity to avoid the exacerbation of inflammation, but any dysregulation can probably be associated with CVDs. (biomedcentral.com)
  • Many studies have further demonstrated that SARS-CoV-2 (COVID-19) has dramatically increased the risks of CVDs due to inflammation, so PGRN has drawn much more attention among scholars. (biomedcentral.com)
  • We also discussed the advantage and challenges of mitochondrial transfer strategies, including cell-based mitochondrial transplantation, extracellular vesicle-based mitochondrial transplantation, and naked mitochondrial transplantation, for the treatment of cardiovascular disorders. (frontiersin.org)
  • These studies suggest novel mechanisms involved in the development of affective disorders, and highlight the noradrenergic system in the vBNST as a common substrate for the manifestation of pathological anxiety and addiction. (nature.com)
  • Sleep fragmentation results from the increase in overnight arousals and may be exacerbated by the increasing number of geriatric medical conditions, including sleep apnea, musculoskeletal disorders, and cardiopulmonary disease. (medscape.com)
  • Tau is a protein that is important in neuronal function, but can misfold and aggregate into pathological structures that accumulate in neurodegenerative disorders such as Alzheimer's disease. (utsa.edu)
  • Spinal cord injury, arthritis, back disorders, cerebral palsy, neuromuscular disorders, fibromyalgia, and other physiological problems also affect a person's ability to move, something that cannot always be adjusted with prosthetics alone 2 . (uab.edu)
  • Although this constituted a major advance in spine surgery that was subsequently applied to a much wider range of pathological disorders and which remains in use today, the method of onlay posterior grafting, when performed in isolation, suffered from an unacceptably high rate of pseudarthrosis (failed fusion). (medscape.com)
  • Although the exact role of cellular microparticles remains partially understood, there is increasing evidence to suggest an active role for microparticles in PH pathophysiology. (ersjournals.com)
  • Indeed, IS is a very complex phenomenon which is influenced not only by the cellular metabolic status but also interacts with circulating molecules such as hormones (including insulin), nutrients and inflammatory molecules. (biomedcentral.com)
  • As the aging process, a complex biological phenomenon witnessed across unicellular and multicellular eukaryotic organisms leads to a functional decline induced by the progressive dysregulation of cellular and organismal functions. (decodeage.com)
  • Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and pathological conditions. (biomedcentral.com)
  • For example, congregate data in the United States have demonstrated that Caucasians have a moderate rate of abdominal obesity relative to other ethnic groups, but experience a lower rate of cardiovascular disease and type II diabetes. (lifebeatnewspaper.com)
  • In contrast, Native (Indigenous) Americans have similar rates of abdominal obesity but considerably higher rates of cardiovascular disease and type II diabetes. (lifebeatnewspaper.com)
  • In the paper the authors provide a wealth of data and evidence for psychological and physiological deterioration that are quite consistent, statistically significant, and measurable throughout multiple studies when it comes to extended mask use. (collective-spark.xyz)
  • Aging is a process of deterioration of physiological functions, time-dependent, leading to homeoestenosis. (medcraveonline.com)
  • Human aging comprising the progressive deterioration, time-dependent functions of the adult organism with a homeoestenosis key physiological systems (nervous, endocrine, immune, cardiovascular and musculoskeletal), which goes from the robustness to frailty, illness, disability and ending in death [1,2]. (medcraveonline.com)
  • Aging changes in the musculoskeletal system, such as cell senescence and alterations in the matrix of joint tissues, can increase the susceptibility to OA. (decodeage.com)
  • CONCLUSIONS: We demonstrated for the first time a significant association of NDUFC2 variants with LVH in human hypertension and highlight a key role of Ndufc2 deficiency-dependent CI mitochondrial dysfunction on increased susceptibility to cardiac hypertrophy development. (bvsalud.org)
  • Children are particularly vulnerable and may be more likely to receive inappropriate treatment or additional harm…Special attention must be paid to the respiration of children, which represents a critical and vulnerable physiological variable due to higher oxygen demand, increased hypoxia susceptibility of the CNS, lower respiratory reserve, smaller airways with a stronger increase in resistance when the lumen is narrowed. (collective-spark.xyz)
  • The overexpression of P450s, esterases, and a UDP-glycosyltransferase, might be responsible for the multi-insecticide resistance in SEF-R. The knockdown of CYP6CY3 in SEF-R increased its susceptibility to imidacloprid, thiacloprid, and thiamethoxam, which verified that P450s play vital roles in neonicotinoid metabolism. (preprints.org)
  • Advanced glycation end products (AGEs) are a consequence of oxidative stress which occur during normal physiological conditions such as aging. (hindawi.com)
  • In summary, cells and tissues are at the forefront of biological research, driving advancements in disease understanding, therapeutic interventions, drug development, and more. (filosofia-internet.net)
  • Patients with metabolic syndrome (MetS) have an increased risk of cardiovascular disease. (biomedcentral.com)
  • Dr Bruestle is currently investigating the interaction of Th17 cells and neutrophils and the direct pathological effects of NETs on neurons and the kind of damage seen in MS. She uses genetic- and inhibitor-mediated manipulation of Th17 cell and/or neutrophil function to explore potential drug targets for MS and to identify molecules involved in this process as biomarkers for disease progression and treatment efficacy. (aips.net.au)
  • We feel this is especially true if the problem is a little more serious than the occasional case of chilly extremities, in the case of Raynaud's Phenomena or Raynaud's Disease. (doctorschar.com)
  • Inhibition of these latter pathways may be a therapeutic target to prevent the elongation which is associated with increased binding of atherogenic lipids and the disease process of atherosclerosis. (openbiochemistryjournal.com)
  • In the last decades, numerical simulations have been widely used to assess the blood flow behavior in stenotic arteries and, consequently, providing insights into the cardiovascular disease condition, its progression and therapeutic optimization. (openbiomedicalengineeringjournal.com)
  • Studies have shown that cell-to-cell mitochondrial transfer plays an essential role in regulating cardiovascular system development and maintaining normal tissue homeostasis under physiological conditions. (frontiersin.org)
  • The work examined advances in spectroscopic methods, especially Raman spectroscopy and combinatorial spectroscopic or optical procedures to analyze cells and tissue in pathological samples. (news-medical.net)
  • Immunohistochemistry and radiolabelling have revolutionized the visualization and detection of compounds in pathological tissue samples. (news-medical.net)
  • Extracellular matrix is a fibrillar network composed of structural (collagens) and adhesion (fibronectin) proteins crucial for tissue architecture and biological pathway Histol Histopathol 27:1515-1528, 2012 . (springer.com)
  • The extracellular matrix is essential for the architecture of the tissue and a myriad of associated biological functions. (springer.com)
  • These changes in gene expression alter cell metabolism, tissue re-modeling, and even organismal responses such as increases in heart rate and ventilation. (nobelprize.org)
  • Besides, obesity in childhood and adolescence can lead to social stigma and isolation, decreased life expectancy, a high frequency of sick leave, disability pension, and increased mortality. (springermedizin.at)
  • Genetic, environmental, behavioral and dietary factors influence the pathways that regulate aging and life expectancy, thus rendering longevity a very complex phenomenon. (iospress.com)
  • There is increasing evidence life expectancy and health, occurring an embodiment dynamic occurs dif- that chronic psychosocial stress may upstream of typically identified risk ferentially across the strata of SEP. (who.int)
  • The vertical axis represents relative risk, level of probable pathological organism response where normal level is 1. (anti-agingfirewalls.com)
  • The biopsychosocial model is a way of thinking about pathological manifestations as an interaction between biological, psychological, and socio-environmental influences . (lifebeatnewspaper.com)
  • Many of these theories have been disproved or abandoned for lack of evidence to support them and others continue providing plausible explanations, although insufficient to cover all sides of a process holistically speaking, is multifactorial and in which are embedded the genetic background, biological changes and psychological, social and environmental conditions where human beings live and develop. (medcraveonline.com)
  • Condensing theories and taking into account all essential to consider the human being as being (biological, psychological and social), the author proposes a classification which, although not complete, intended to be comprehensive (Table 1) spheres. (medcraveonline.com)
  • Aging is a biological and psychological phenomenon that affects the family and social level. (bvsalud.org)
  • Aging is a physiological process that involves all living things and is connected to the loss of skills, the way of life in the past, genetics, and emotional and psychological changes. (bvsalud.org)
  • The phenomenon of intercellular mitochondrial transfer has been discovered in the cardiovascular system. (frontiersin.org)
  • In this review, we summarized the mechanism of mitochondrial transfer in the cardiovascular system and outlined the fate and functional role of donor mitochondria. (frontiersin.org)
  • Given the complexity of the biological function of mitochondria, researchers have begun to consider rescuing the injured cells through mitochondrial transfer, that is, replacing damaged mitochondria with healthy mitochondria from donor cells. (frontiersin.org)
  • can act as donors or recipients during mitochondrial transfer under physiological conditions ( 8 - 12 ). (frontiersin.org)
  • Biological factors included in this model take account of genetic background (nuclear and mitochondrial), local and systemic metabolomic environments, and abnormal physiology and histology, among other factors. (lifebeatnewspaper.com)
  • Scientists from Singapore were able to demonstrate in their Ib study published in the renowned journal "nature" that 106 children aged between 7 and 14 years who wore FFP2 masks for only 5 min showed an increase in the inspiratory and expiratory CO2 levels, indicating disturbed respiratory physiology. (collective-spark.xyz)
  • The clinical presentation of Acute Respiratory Distress (ARDS) is marked by disruptions to the alveolar-capillary complex mediated by inflammation, interalveolar edema primarily caused by protein-rich fluids influx, reduced alveolar clearance, and increased pulmonary resistance. (ceufast.com)
  • Patients with PH exhibited higher circulating levels of microparticles compared to control subjects and in vitro or in vivo generated microparticles can induce endothelial dysfunction, interfere with coagulation pathways or modulate inflammatory phenomenon. (ersjournals.com)
  • The main obstacle is because many protein components of mitochondria are the network hubs of multiple biological pathways. (frontiersin.org)
  • The Pittcon 2019 Technical Program was held in Philadelphia from March 17th-21st, 2019 and showcased a range of biomedical methodologies which can provide improved diagnostics, better treatments, faster discovery and ultimately improved medical outcomes. (news-medical.net)
  • Behavioral and social factors are important contributors to health and illness and frequently interact with biological factors to influence health outcomes. (nih.gov)
  • BACKGROUND: Improvement in radiotherapy techniques and expected outcomes, as well as in understanding the underlying biological mechanisms contributing to its action (immunomodulation in primis), led to the integration of this therapeutical approach in the current management of advanced non-small cell lung cancer (NSCLC), not only in oncogene-driven tumors, but also in non-oncogene addicted NSCLC where the combination of platinum-based chemotherapy plus pembrolizumab represents nowadays the pivotal strategy. (bvsalud.org)
  • However, very little data are available on IS of circulating cells of MetS patients although clinical data show that inhibited mTOR, with specific inhibitors such as Serolimus or Everolimus after kidney transplantation, significantly increase the presence of de novo thrombotic micro-angiopathy with artery lesion characterized by intimal cell proliferation, necrosis and narrowed lumen. (biomedcentral.com)
  • However, despite growing biological and clinical significance, little is known about the structural arrangement of this receptor or any of its family members. (uci.edu)
  • and a focus on both the social and biological contexts of behavior. (nih.gov)
  • social and biological phenomena. (who.int)
  • In pathological conditions, damaged cells transfer dysfunctional mitochondria toward recipient cells to ask for help and take up exogenous functional mitochondria to alleviate injury. (frontiersin.org)
  • That is, it is to keep conditions wihthin a normal functioning range and also improve that functioning. (anti-agingfirewalls.com)
  • however, a progressive increase of sick people, elderly people in particular, which are affected by multiple chronic conditions [ 8 ], will render this approach less and less sustainable. (iospress.com)
  • In vivo studies represent more accurately the physiological conditions and provide the most realistic data. (openbiomedicalengineeringjournal.com)
  • Over the years, these cardiovascular complications have been extensively studied by applying in vivo , in vitro and numerical methods ( in silico ). (openbiomedicalengineeringjournal.com)
  • Analysis of the visceral hypothesis of sleep shows that many pathological states associated with the sleep-waking cycle can be explained in terms of impairments to the synchronicity of the switching of information streams in the cerebral cortex going from waking from sleep and vice versa. (researchgate.net)
  • Longden T , Dabertrand F, Koide M, Gonzales A, Tykocki N, Brayden J, Hill-Eubanks D, Nelson M (2017) " Capillary K+-sensing initiates retrograde hyperpolarization to locally increase cerebral blood flow " Nature Neuroscience , 20: 717-726. (umaryland.edu)
  • Such extracts usually include a mixture of compounds that can act by affecting different physiological functions, sometimes causing undesirable effects. (scielo.br)
  • Nowadays, more and more studies have revealed that cells in the cardiovascular system (such as cardiomyocytes, vascular smooth muscle cells, endothelial cells, et al. (frontiersin.org)
  • A reduced expression of mTOR may reflect an increased risk of vascular thrombosis. (biomedcentral.com)
  • There are two PH components: 1) passive transmission of increased left atrial pressure, 2) HF-related pulmonary vascular dysfunction (PVD) with increased vascular resistance. (cas.cz)
  • They demonstrated that transferring functional mitochondria of bone marrow-derived stem cells to defective parenchymal cells increases the aerobic respiration capacity of recipient mitochondria ( 7 ). (frontiersin.org)
  • A hormetic response to a stress not only maintains a functional internal environment but also improves it. (anti-agingfirewalls.com)
  • Doctor Peterson wrote this in 1905, "Xanthoxylum (Prickly Ash) stimulates the nerve centers and thus increases the functional activity of the different organs of the body. (doctorschar.com)
  • On the other hand, the number of circulating hEPC is increased in hypoxia or acute myocardial infarction (AMI). (intechopen.com)
  • In recent years, the field of biology and scientific research has witnessed an increasing interest from investors seeking to support advancements in these fields through financial means. (filosofia-internet.net)
  • Tom's graduate studies were sponsored by a Biotechnology and Biological Sciences Research Council (BBSRC) Collaborative Award in Science and Engineering (CASE) fellowship, with Boehringer Ingelheim as an industrial sponsor, and focused on the role of the astrocytic intermediate-conductance calcium-activated potassium channel in neurovascular coupling. (umaryland.edu)
  • Our research involves applying mass spectrometry-based techniques to perform metabolomics, lipidomic and proteomic analysis of various biological samples. (cas.cz)
  • Note - Research has shown testicular extracts contain nearly undetectable levels of testosterone that are insufficient to have a biological effect, so please do not consider seeking out or using testicular extracts to directly increase your T levels! (interplexus.com)
  • After completing his Bachelors in Physics at UC Berkeley, where he was awarded the University Medal, Mekhail received his medical degree at UC San Francisco, and Ph.D. in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology where his research focused on using micro-fabricated devices for biological detection. (nih.gov)
  • Over the last decade, mass spectrometry-based metabolomics and lipidomics have become the key platforms for the comprehensive profiling of polar metabolites and complex lipids in biological samples (plasma, serum, urine, and tissues). (cas.cz)
  • it also allowed the development of complex physiological responses. (nobelprize.org)
  • Nevertheless, these approaches are expensive, and it is complex to control several physiological variables. (openbiomedicalengineeringjournal.com)
  • In the past 3 decades, increased understanding of spinal biomechanics, proliferation of sophisticated spinal instrumentation devices, advances in bone fusion techniques, refinement of anterior approaches to the spine, and development of microsurgical and minimally invasive methods have made it possible to stabilize every segment of the spine successfully, regardless of the offending pathology. (medscape.com)
  • Living systems on earth are governed by many natural laws, but circadian rhythms play one of the most important roles in sustaining organisms, acting as the biological timekeepers that perpetuate life from mere seconds to the full Gregorian year. (frontiersin.org)
  • This traditional approach has now changed as well as considering the role of evolution in aging, divide the theories into two broad categories: biological, where it continues case aging as an evolutionary event genetically controlled, and chemical as a somatic process resulting from the cumulative chemical damage to bio molecules [10,11]. (medcraveonline.com)
  • Whether or not these new conveyors of biological information contribute to the acquisition and/or maintenance of the altered endothelial phenotype is unexplored in PH and requires further study. (ersjournals.com)
  • After the Raynaud's phenomena fact sheet you will find what I discovered regarding its general health stimulating effects. (doctorschar.com)
  • In conclusion, adverse hemodynamic effects of specific design features (such as strut size and narrow spacing) can be mitigated when combined with other hemodynamically beneficial design features but increased luminal protrusion can worsen the stent's hemodynamic profile significantly. (researchgate.net)
  • Furthermore, the precise pathophysiological characteristics underlying the association of different cardiovascular risk factors in MetS remain elusive [ 5 ]. (biomedcentral.com)
  • Risk profiles are a tool of preventative medicine, to address potential pathological events down the line and address root causes. (lifebeatnewspaper.com)
  • There is a consistent pattern of increased risk for glioma (a malignant brain tumor) and acoustic neuroma with use of mobile and cordless phones according to studies from Orebro University, Sweden released in 2012 and 2013. (bioinitiative.org)
  • It defines the dichotomy whereby and risk factors with biological mea- sociation between the overall social individuals actively determine the surements (Vineis et al. (who.int)
  • In humans, açai supplementation indicated positive results in increasing exhaustion time to 90% of VO and increasing intensity at the anaerobic threshold. (bvsalud.org)
  • We also focus on improving data processing, automated data curation, statistical methods, and visualization of omics data. (cas.cz)
  • The Ph.D. project aims to focus on novel approaches for comprehensive characterization of the metabolome and lipidome in biological samples, specifically, (i) merging targeted and untargeted methods, (ii) increasing the coverage of spectral libraries used for metabolite annotation, and (iii) using bioinformatics tools for visualization and interpretation of the data obtained within metabolomics and lipidomics studies. (cas.cz)
  • Microfluidic systems are more cost effective than traditional methods, require minimal training, provide faster results and improved accuracy. (news-medical.net)
  • The socioeconomic gradient in and biological systems. (who.int)
  • The lab's model qubit is the Nitrogen-Vacancy center in diamond, which they use to image magnetic phenomena in condensed-matter and biological systems over a broad range of length scales. (nih.gov)
  • These systems comprise the CDC Sickle Cell Data Collection (SCDC) program, which includes comprehensive data linkages from multiple data systems.2 These data, which include information about demographics, payer, and health care utilization, identify opportunities for improving access to care. (cdc.gov)
  • The alterations in Sprague-Dawley rats were accompanied by an increase in anxiety-like behavior in those animals as measured with the elevated plus maze. (nature.com)
  • She will then study how neurons grow, form connections and consequently re-attain their physiological circuit functions. (aips.net.au)
  • Overall, this work reinforces the evidence that specific eating habits, in addition to healthy and active lifestyles, are crucial to increase people's health span and to achieve an optimal longevity. (iospress.com)
  • An important strategy for achieving this goal is to increase opportunities for investigators in low and middleincome countries to contribute their studies in these areas to the scientific literature. (cdc.gov)
  • Our studies use experimental autoimmune encephalomyelitis (EAE) as a model to investigate pathological events related to Multiple Sclerosis. (utsa.edu)