• This study focused on the changes in biofilm activity and related metabolic pathways of S. aureus treated with lactic acid bacteria planktonic CFS (LAB-pk-CFS) and biofilm state (LAB-bf-CFS). (frontiersin.org)
  • However, there have not been many investigations on how pathogenic bacteria are affected by the metabolic properties of planktonic and biofilm probiotics. (frontiersin.org)
  • Here, we used untargeted metabolomics to investigate the potential impacts of planktonic bacteria (LAB-pk-CFS) and biofilm colonies (LAB-bf-CFS) on the metabolism of S. aureus biofilms. (frontiersin.org)
  • We applied this strategy to study coagulase (Coa), a secreted protein and a major contributor to the formation of a fibrin network in S. aureus biofilms that protects bacteria from the host immune system and increases attachment to host surfaces. (sdu.dk)
  • [13] The biofilm bacteria can share nutrients and are sheltered from harmful factors in the environment, such as desiccation, antibiotics, and a host body's immune system. (wikipedia.org)
  • They can be found very early in Earth's fossil records (about 3.25 billion years ago) as both Archaea and Bacteria, and commonly protect prokaryotic cells by providing them with homeostasis, encouraging the development of complex interactions between the cells in the biofilm. (wikipedia.org)
  • [8] [5] The first colonist bacteria of a biofilm may adhere to the surface initially by the weak van der Waals forces and hydrophobic effects. (wikipedia.org)
  • During biofilm formation the bacteria sense a range of environmental cues and interpret these as signals to cluster. (cmrf.org.nz)
  • Once S. aureus adheres to host tissues, it can form biofilms, which enable its persistence by allowing bacteria to evade host defences, impeding access to certain types of immune cells, such as macrophages, which display incomplete penetration into the biofilm matrix and "frustrated phagocytosis" [ 7 ]. (biomedcentral.com)
  • Hydrophobicity can also affect the ability of bacteria to form biofilms. (wikipedia.org)
  • From the results obtained, it can be concluded that food is a source of coagulase-negative staphylococci capable of forming biofilm, which is referred to as clinically important virulent factor of these bacteria. (edu.pl)
  • Simultaneously, the biofilm of bacteria plays an important role in antibiotic resistance and chronic infection. (figshare.com)
  • In this study, the anti-biofilm activity of previously fabricated polyamino-phenolic ligands and polyamidoamine dendrimers was investigated against legionella mono-species and multi-species biofilms formed by L. pneumophila in association with other bacteria that can be found in tap water ( Aeromonas hydrophila , Pseudomonas aeruginosa , Escherichia coli , Klebsiella pneumoniae ). (frontiersin.org)
  • Biofilm is a complex matrix consisting of extracellular polysaccharides, DNA, and proteins that protect bacteria from a variety of physical, chemical, and biological stresses allowing them to survive in hostile environments. (intechopen.com)
  • Bacteria can be found in planktonic form or in specific conditions, as sessile aggregates on both biotic and abiotic surfaces originating complex structures known as biofilm. (intechopen.com)
  • The biofilm matrix consists of polysaccharides, proteins, and DNA and constitutes a stubborn source that protects bacteria from a variety of physical, chemical, and biological stresses. (intechopen.com)
  • [ 4 ] Within 2 weeks, the bacteria within the tubing and bag have had ample opportunity to create a biofilm, providing a safe haven against most antibiotics. (medscape.com)
  • Under a high magnification, this scanning electron microscopic (SEM) image depicted numbers of Staphylococcus aureus bacteria, which were found on the luminal surface of an indwelling catheter. (cdc.gov)
  • This biofilm has been found to protect the bacteria that secrete the substance from attacks by antimicrobial agents such as antibiotics. (cdc.gov)
  • Examples of bacteria that cause infections include Streptococcus , Staphylococcus , and E. coli . (medlineplus.gov)
  • This study aims to develop a sinonasal tissue explant model to analyze the interaction of S. aureus biofilm with the mucosa in vitro. (edu.au)
  • Methods: Sinonasal tissue samples from 5 control patients undergoing pituitary surgery were cultured with and without S. aureus biofilm in vitro. (edu.au)
  • Methods: The ability of S. aureus S54F9 to form biofilm was tested in vitro. (ku.dk)
  • Results: S. aureus S54F9 showed an ability to form biofilm in vitro. (ku.dk)
  • Results demonstrate that very high concentrations of the most used antibiotics in treating diabetic foot infections (DFI) are required to inhibit S. aureus biofilms in vitro, which may explain why monotherapy with these agents frequently fails to eradicate biofilm infections. (biomedcentral.com)
  • Among 81 CNS included in the current study, 84% showed ability to form biofilm in the experimental in vitro conditions. (edu.pl)
  • The aim of the present study was to test for the presence of genes involved in capsular polysaccharide production and biofilm formation in S. aureus isolated from bovine mastitis samples collected from 119 dairy herds located in three different Brazilian regions, as well as to assay the production of capsular polysaccharides and biofilm , in vitro . (bvsalud.org)
  • Baicalin acts as an adjuvant to potentiate the activity of azithromycin against Staphylococcus saprophyticus biofilm: an in vitro, in vivo, and molecular study. (greenmedinfo.com)
  • Rutin partially inhibits biofilm formation in Staphylococcus xylosus ATCC700404 in vitro and in vivo. (greenmedinfo.com)
  • Mechanical removal of biofilm on titanium discs: An in vitro study. (gu.se)
  • Bacterial biofilms are the major cause of chronic wound infections and are notoriously recalcitrant to treatments with antibiotics, making them difficult to eradicate. (umf.org.nz)
  • Hyperthermophilic archaeon Pyrobaculum calidifontis produce bundling pili which are homologous to the bacterial TasA filaments, a major component of the extracellular matrix in bacterial biofilms, which contribute to biofilm stability. (wikipedia.org)
  • Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)
  • Bacterial biofilms can generate micro-heterogeneity in terms of surface structures. (elifesciences.org)
  • Failure of antibiotic treatments is often attributed to formation of bacterial biofilms and abscesses in the mammary gland tissue, which lead to chronic infections that are difficult to eradicate and drive recurrent disease. (ntu.edu.tw)
  • Other combinations of Medihoney and antibiotic produced an interesting array of effects: Medihoney-fusidic acid treatment showed minor synergistic activity, and Medihoney-clindamycin, -gentamicin, and -oxacillin combinations showed overall antagonistic effects when the honey was used at sub-inhibitory concentration, due to enhanced biofilm formation at these concentrations which could not be counteracted by the antibiotics. (umf.org.nz)
  • The experimental and genomic data presented here open the venue to further investigations on the molecular basis underlying biofilm inhibition. (unisa.it)
  • Here, we confirmed that rutin can effectively inhibit biofilm formation in S. xylosus, of which the inhibition mechanism involves its ability to interact with imidazole glycerol phosphate dehydratase (IGPD), a key enzyme in the process of biofilm formation. (figshare.com)
  • In this study, we demonstrate that octanoic acid has broad-spectrum microbicidal activity against MCPs and effectively inhibits S. aureus biofilm formation in milk (>50% inhibition at 3.13 mM). (ntu.edu.tw)
  • The concentration of the chemicals tested as anti-biofilm agents was chosen based on cytotoxicity assays: the highest non-cytotoxic chemical concentration was used for biofilm inhibition assays, with dendrimer concentration 10-fold higher than polyamino-phenolic ligands. (frontiersin.org)
  • Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)
  • To this end, the anti-biofilm effect of cell-free supernatant of Pseudomonas sp. (unisa.it)
  • Propolis mampu menghambat pembentukan biofilm dengan cara mendegradasi extracellular polymeric substance (EPS), mengurangi motilitas bakteri Pseudomonas aeruginosa dan mengacaukan fungsi autoinducer AHL. (ub.ac.id)
  • Proteus and Pseudomonas species are the organisms most commonly associated with biofilm growth on catheters. (medscape.com)
  • The Methicillin-resistant Staphylococcus aureus (MRSA) isolates were screened to determine their biofilm producing ability using crystal binding assay. (ajol.info)
  • All the MRSA isolates tested for the presence of biofilm showed positive results. (ajol.info)
  • Biofilm production for 182 MRSA isolates obtained from clinical culture sites (2004 to 2013) was quantified. (uri.edu)
  • Of the isolates evaluated, 25.8% (47/182) produced strong biofilms and 40.7% (74/182) produced weak biofilms. (uri.edu)
  • Consequently, we can assume that the adhesive properties and increase the level of teichoic acids from clinical isolates of S. aureus is a sign of pathogenicity and virulence, which may affect the ability of microorganisms to biofilm formation. (scholarsresearchlibrary.com)
  • The only antibiotics able to inhibit biofilm eradication on 50 % of isolates were ceftaroline and gentamicin. (biomedcentral.com)
  • The ability of the isolates to form a biofilm was examined using the polystyrene surface of microtiter plates. (bvsalud.org)
  • Of the 159 isolates analysed, 97.5 % were biofilm producers. (bvsalud.org)
  • A significant association between the capsular genotype and phenotype and the amount of biofilm formation was detected cap5/CP5 isolates tended to form more biofilm and to produce a thinner CP layer than cap8/CP8 isolates. (bvsalud.org)
  • Biofilm formation of isolates that was investigated by using Congo Red agar method. (turkhijyen.org)
  • RESULTS: Total of 56 isolates of Staphylococcus spp. (turkhijyen.org)
  • In this study, % 50 of S. aureus and % 18 of CNS from minced and 41.5 % of CNS isolates from chicken samples produced biofilm, respectively. (turkhijyen.org)
  • In this study, we showed that a large proportion of isolates had biofilm production and DNase activity. (turkhijyen.org)
  • The minimum biofilm eradication concentration was usually two times higher than the minimum bactericidal concentration, yet it was never higher than 1% v/v. The fastest killing of biofilm occurred during the first 15min of contact with TTO and was not influenced by increasing TTO concentration above 1% v/v. Planktonic stationary phase cells exhibited decreased susceptibility to TTO compared with exponential phase cells. (nih.gov)
  • The antibiotic minimum inhibitory concentration (MIC) was determined for ten antimicrobial compounds, along with the minimum biofilm inhibitory concentration (MBIC) and minimum biofilm eradication concentration (MBEC), followed by PCR identification of genetic determinants of biofilm production and antimicrobial resistance. (biomedcentral.com)
  • All clinical strains tested were killed by TTO both as planktonic cells and as biofilms. (nih.gov)
  • To date, the mechanisms of biofilm formation are not well understood, therefore the purpose of this study was to determine the relationship between the adhesive properties, the level of teichoic acids and the ability to form biofilms of clinical and reference strains of Staphylococcus aureus. (scholarsresearchlibrary.com)
  • In one ICU out of ten, the molecular characteristics, antimicrobial susceptibility profiles and biofilm production of the strains responsible for S. aureus bacteremia were studied. (hal.science)
  • Under static conditions and without exposure to glucose, biofilm production was rare (9.4% of the strains, without any CC398). (hal.science)
  • These infections are often recurrent and increasing numbers are being caused by strains like methicillin-resistant Staphylococcus aureus (MRSA), which are resistant to nearly all known antibiotics. (cmrf.org.nz)
  • In this study, we analysed the antimicrobial susceptibility patterns of biofilm-producing S. aureus strains isolated from diabetic foot infections. (biomedcentral.com)
  • High biofilm capacity was demonstrated in 54% of strains, the average in 14%, and low in 16%, while the lack of biofilm production capacity was found in 16% of the tested strains. (edu.pl)
  • In this section, we will focus on proteins involved in biofilm formation as useful targets for the development of new drugs that can effectively and specifically impair biofilm formation with slight effects on cell survival, thus avoiding the generation of drug-resistant strains. (intechopen.com)
  • TAE6080, a possibly new bacterium isolated in 1994 during water column samplings near the French Antarctic station Dumont d'Urville, is capable of inhibiting the formation of Staphylococcus epidermidis biofilm, known to be an important opportunistic pathogen in infections associated to medical devices. (unisa.it)
  • Manuka honey has potent broad-spectrum antibacterial activity and has previously shown synergistic activity in combination with antibiotics against common wound pathogens, including Staphylococcus aureus . (umf.org.nz)
  • Candida albicans and Staphylococcus aureus , representing two different kingdoms, are the most frequently isolated pathogens from invasive infections. (mdpi.com)
  • Drinking water pipe biofilms control microbial regrowth and are a possible source of pathogens. (who.int)
  • Dental plaque biofilm may promote oral and oropharyngeal colonization of respiratory pathogens in hospitalized subjects. (who.int)
  • In January 2021, the Department of Internal pathogens characterized as strong biofilm producers that Medicine - Infectious Disease and Infection Prevention are resistant to most antimicrobials. (who.int)
  • This study is aimed at investigating biofilm and enterotoxin producing capacity of methicillin-resistant Staphylococcus aureus isolated from nostrils of healthy students of Delta State University Oleh campus. (ajol.info)
  • Determination of methicillin-resistant Staphylococcus aureus was carried out with the aid of Oxacillin sensitivity disc to test the presence of penicillin binding protein2a (PBP2a). (ajol.info)
  • The molecular and clinical factors associated with biofilm-forming methicillin-resistant Staphylococcus aureus (MRSA) are incompletely understood. (uri.edu)
  • It has been observed that MRSAs are capable of producing biofilms and enterotoxins which pose the risk antibiotic resistance and human Staphylococci toxicity. (ajol.info)
  • Staphylococcus xylosus (S. xylosus) has become an emerging opportunistic pathogen due to its strong biofilm formation ability. (figshare.com)
  • The microorganisms in biofilms composed of 50-500 times increase their resistance to disinfectants, antimicrobials, bacteriophages, phagocytes and antibodies. (scholarsresearchlibrary.com)
  • A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. (wikipedia.org)
  • Biofilms can attach to a surface such as a tooth or rock, and may include a single species or a diverse group of microorganisms. (wikipedia.org)
  • The formation of a biofilm begins with the attachment of free-floating microorganisms to a surface. (wikipedia.org)
  • The devices become colonized by the microorganisms that form a biofilm of cells, the detachment of which can result in septicemia ( 2 - 5 , 8 , 9 , 14 , 15 ). (cdc.gov)
  • Biofilms are universal, complex, interdependent communities of surface-associated microorganisms. (cdc.gov)
  • Most microorganisms grow in structured biofilms rather than individually in suspensions and while in this environment may display altered phenotypes ( 2 ) . (cdc.gov)
  • Disinfection methods currently used in water systems have been shown to be ineffective against legionella over the long-term, allowing recolonization by the biofilm-protected microorganisms. (frontiersin.org)
  • Many such manifestations of infections associated with the formation of Candida biofilms include those occurring on devices such as indwelling intravascular catheters. (cdc.gov)
  • Biofilm-associated Candida show uniform resistance to a wide spectrum of the currently available conventional antifungal agents, which implies that antimicrobial drugs that specifically target biofilm-associated infections are needed. (cdc.gov)
  • The novel classes of antifungal agents, the lipid formulation of amphotericins, and the echinocandins have demonstrated unique antifungal activity against the resistant Candida biofilms, providing a breakthrough in the treatment of life-threatening invasive systemic mycoses. (cdc.gov)
  • Most manifestations of candidiasis are in fact associated with the formation of Candida biofilms on surfaces, and this phenotype is associated with infection at both the mucosal and systemic sites ( 8 ) . (cdc.gov)
  • Staphylococcus aureus , followed by coagulase-negative staphylococci, Streptococcus pneumoniae and Klebsiella pneumoniae . (who.int)
  • The microbial community is also a natural source of metabolites and has the potential to be used to create antimicrobial and anti-biofilm agents. (frontiersin.org)
  • OBJECTIVE: In this study, it was aimed to evaluate calf minced meat and chiken drumsticks samples purchased from different supermarkets in Ankara, Turkey for the presence of coagulase positive staphylococci (CPS) and coagulase negative staphylococci (CNS) and to determine their biofilm production and DNase activity. (turkhijyen.org)
  • Confocal scanning laser microscopy confirmed that different honey-antibiotic combination treatments could eradicate biofilms. (umf.org.nz)
  • The results suggest that the antibiotic susceptibility patterns cannot be applied to biofilm established infections. (biomedcentral.com)
  • Treatment of lapine knees infected with Staphylococcus aureus with the antibiotic-eluting UHMWPE led to complete bacterial eradication and the absence of detectable systemic effects. (nature.com)
  • Additionally, octanoic acid rapidly kills persistent biofilm cells and cells with antibiotic tolerance (within 4 h). (ntu.edu.tw)
  • In contrast, antibiotics treated at >100X MBC cannot eradicate biofilms but do induce SCVs and antibiotic-tolerant cells. (ntu.edu.tw)
  • Thus, octanoic acid exhibits bactericidal action against S. aureus biofilms, and it is less likely than antibiotic therapy to induce persistent cells and pathogen tolerance. (ntu.edu.tw)
  • The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single cells that may float or swim in a liquid medium. (wikipedia.org)
  • Microbes form a biofilm in response to a number of different factors, [9] which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics . (wikipedia.org)
  • In fact, biofilms were resistant to antibiotics at concentrations 10-1000 times greater than the ones required to kill free-living or planktonic cells. (biomedcentral.com)
  • Using checkerboard microdilution assays, viability assays and MacSynergy II analysis we show that the Medihoney-rifampicin combination was more effective than combinations using the other antibiotics against established staphylococcal biofilms. (umf.org.nz)
  • Medihoney and rifampicin were strongly synergistic in their ability to reduce both biofilm biomass and the viability of embedded S. aureus cells at a level that is likely to be significant in vivo . (umf.org.nz)
  • Furthermore, it significantly reduced biofilm biomass and cell viability in a dose-dependent manner. (unict.it)
  • Bacterial ability to form biofilms was verified using a crystal violet colorimetric assay and testing cell viability by real-time quantitative PCR and Plate Count assay. (frontiersin.org)
  • The technique allowed for the simultaneous imaging of changes in biofilm structure and disruption of cellular membrane integrity through the loss of an unbound fluorophore loaded into bacterial cells prior to antimicrobial challenge. (montana.edu)
  • Nisin caused a rapid and uniform loss of green fluorescence from all parts of the biofilm without any removal of biofilm. (montana.edu)
  • Four teeth were analyzed by scanning electron microscopy (SEM) to confirm the presence of biofilm. (bvsalud.org)
  • This study aims to make inhibitors of the bacterial enzymes that make menaquinone to study how menaquinone affects biofilm formation which will lead to drugs to target and treat S. aureus infections and biofilms. (cmrf.org.nz)
  • We report here that myricetin, but not its glycosylated form, can remarkably decrease the production of several S. aureus virulence factors, including adhesion, biofilm formation, hemolysis and staphyloxanthin production, without interfering with growth. (nature.com)
  • Several structural and secreted virulence factors play a role in S. aureus infections, which are multifactorial and depend on bacterial adherence and biofilm formation. (biomedcentral.com)
  • These data show that TTO efficiently kills S. aureus in the stationary growth phase and within biofilms and is therefore a promising tool for S. aureus eradication. (nih.gov)
  • Octanoic acid effectively clears biofilms (95% eradication at 1X minimum bactericidal concentration, MBC) and infrequently induces S. aureus small colony variants (SCVs) that may cause recurrent mastitis. (ntu.edu.tw)
  • Staphylococcus aureus is an opportunistic pathogen related to a variety of life-threatening infections but for which antimicrobial resistance is liming the treatment options. (nature.com)
  • Staphylococcus aureus is an important human opportunistic pathogen involved in a wide range of human infections. (nature.com)
  • After the irrigation protocol, the biofilm susceptibility to disinfecting solutions (n=10) was determined by colony-forming unit (CFU) quantification. (bvsalud.org)
  • In man-made water systems microbial biofilms increase the resistance of legionella to disinfection, posing a significant threat to public health. (frontiersin.org)
  • These data suggest that the studied compounds, especially dendrimers, could be considered as novel molecules in the design of research projects aimed at the development of efficacious anti-biofilm disinfection treatments of water systems in order to minimize legionellosis outbreaks. (frontiersin.org)
  • Conclusion: The sinonasal tissue explant is a viable and functional model capable of analyzing direct biofilm-mucosal interactions and can advance our understanding of the role played by S. aureus biofilm in sinus inflammation. (edu.au)
  • The differentially expressed genes and proteins linked to S. aureus biofilms have been identified using transcriptomic and proteomic investigations ( 14 - 17 ). (frontiersin.org)
  • [2] [3] The cells within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides , proteins , lipids and DNA . (wikipedia.org)
  • Transcriptional analysis performed on the established biofilm revealed that PYED-1 downregulates the expression of genes related to quorum sensing (agrA, RNAIII, hld, psm, and sarA), surface proteins (clfB and fnbB), secreted toxins (hla, hlb, and lukD), and capsular polysaccharides (capC). (unina.it)
  • In conclusion, PYED-1 not only effectively inhibited biofilm formation, but also eradicated preformed biofilms of S. aureus, modulating the expression of genes related to quorum sensing, surface and secreted proteins, and capsular polysaccharides. (unina.it)
  • Additionally, it inhibits the physiological traits of the S. aureus biofilm, including hydrophobicity, motility, eDNA, and PIA associated to the biofilm. (frontiersin.org)
  • Protocols with an optimal visualization of biofilm extracellular matrix were combined with an immunohistochemical protocol based on a specific antibody against S. aureus. (ku.dk)
  • Visualization of biofilm, i.e. bacterial cells and extracellular matrix in different colours, was seen when the immunohistochemical protocol was combined with Alcian Blue pH3, Luna and Methyl-pyronin green. (ku.dk)
  • PYED-1 caused a strong reduction in biofilm formation in a concentration dependent manner. (unina.it)
  • In addition, these devices promote colonization by providing a biofilm surface for bacterial adhesion as well by producing mucosal irritation. (medscape.com)
  • 1) Biofilm formation during bacterial colonization and how the composition of the respiratory microbiota as well as environmental factors (host inflammation, virus infection) modulate or trigger transition from colonization to infection, such as otitis media, pneumonia and sepsis. (lu.se)
  • S. aureus produces large biofilm formations that support its pathogenicity and confer protection and subsequently drug resistance ( 5 ). (frontiersin.org)
  • A biofilm usually begins to form when a free-swimming bacterium attaches to a surface. (wikipedia.org)
  • New Zealand has among the highest reported incidence of infections with the bacterium Staphylococcus aureus in the developed world. (cmrf.org.nz)
  • Staphylococcus aureus is a Gram-positive, round-shaped bacterium that is a member of the Firmicutes, and it is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. (cmrf.org.nz)
  • Legionnaires' disease is a potentially fatal pneumonia caused by Legionella pneumophila , an aquatic bacterium often found within the biofilm niche. (frontiersin.org)
  • Thus, new approaches are required to combat biofilms in chronic wounds. (umf.org.nz)
  • Our results suggest that honey has potential as an adjunct treatment with rifampicin for chronic wounds infected with staphylococcal biofilms. (umf.org.nz)
  • Background: Staphylococcus aureus (S. aureus) biofilm has been associated with severe and recalcitrant cases of chronic rhinosinusitis (CRS). (edu.au)
  • Here, we investigated the effect of PYED-1 on the biofilms of Staphylococcus aureus, an etiological agent of biofilm-based chronic infections such as osteomyelitis, indwelling medical device infections, periodontitis, chronic wound infections, and endocarditis. (unina.it)
  • In summary, our findings provide new insights into the treatment of biofilm mediated persistent infections and chronic bacterial infections. (figshare.com)
  • These effects may accelerate the transition from biofilm to chronic infection. (ntu.edu.tw)
  • Biofilms are an ensemble of microbial cells irreversibly associated with a surface and enclosed in an essentially self-produced matrix. (intechopen.com)
  • Measurements of IL-6, at both the messenger RNA (mRNA) level (using quantitative reverse-transcriptase polymerase chain reaction [qRT-PCR]) and the protein level (using enzyme-linked immunosorbent assay [ELISA]), were undertaken to evaluate biofilm-mucosa interaction. (edu.au)
  • Additionally, biofilm cells display increased tolerance to antibiotics [ 8 ]. (biomedcentral.com)
  • The aim of the study was to analyze the biofilm production capacity of coagulase-negative staphylococci (CNS) isolated from ready-to-eat meat products including pork ham, chicken cold cuts, pork sausage, salami and pork luncheon meat, sliced in the store to the consumer's specifications, along with determination of occurrence of the adhesion genes determining the polysaccharide production (icaA and icaD) and collagen binding protein (cna). (edu.pl)
  • Biofilm growth plays an important role during infection by providing defence against several antagonistic mechanisms. (biomedcentral.com)
  • Staphylococcus aureus is a major human pathogen that utilises many surface-associated and secreted proteins to form biofilms and cause disease. (sdu.dk)
  • Furthermore, genome sequencing, assembly and mining revealed a plethora of putative biosynthetic gene clusters that might be involved in biofilm disruption. (unisa.it)
  • OP, the ability to form biofilms and above was also determined at the level (1,0683 ± 0,006) un. (scholarsresearchlibrary.com)
  • Biofilms may form on living (biotic) or non-living (abiotic) surfaces and can be prevalent in natural, industrial, and hospital settings. (wikipedia.org)
  • [8] Biofilms can form on the teeth of most animals as dental plaque , where they may cause tooth decay and gum disease . (wikipedia.org)