• Our objective was to evaluate the effect of chronic gestational treatment and post-breast feeding with purple grape juice on the biochemical parameters in offspring of dams. (scirp.org)
  • When considering the post-breast feeding factor, grape juice resulted in an improvement in HDL-C. We concluded that purple grape juice was able to produce a beneficial effect on certain biochemical parameters in offspring. (scirp.org)
  • Assessment of the toxic effects of levetiracetam on biochemical, functional, and redox parameters of salivary glands in male Wistar rats. (bvsalud.org)
  • Therefore, the current work investigated the effects of LEV on the biochemical, functional, and redox parameters of the parotid and submandibular glands in rats . (bvsalud.org)
  • Throughout the experiment monitoring the nutritional assessment, anthropometric and biochemical parameters is achieved. (nih.gov)
  • On 21st postnatal day pups were sacrificed and biochemical parameters were assessed. (fluoridealert.org)
  • The anthropometric and biochemical parameters were analyzed on day 71. (greenmedinfo.com)
  • This study investigates the effects of the electromagnetic field (EMF) resulting from the 170 kV high-voltage power lines on hormonal status, on progesterone and 17-beta estradiol levels, and on morphology of the uterus and ovaries associated with biochemical parameters of adult Wistar female rats. (twoday.net)
  • 0.01) in aspartate amino transferase (AST) activity (24.95±0.10 IU L -1 ) and ammonium ion (NH 4 + ) concentration (39.58±0.16 μg mL -1 ) in the rats serum. (scialert.net)
  • In Female rats, supra-therapeutic doses of CGV elevated creatinine levels by 72.2% (1000 mg/kg), 60.2% (2000 mg/kg) and 124.8% (3000 mg/kg) respectively and 3000 mg/kg produces elevated serum low density lipoprotein by 34.6% in treated rats. (biomedcentral.com)
  • Measurements made after the diet had been fed for 28-30 days indicated that Simonsen albino and Wistar strains consistently showed the greatest response, based on degree of thyroid enlargement, depletion of thyroidal iodine, reduction in serum T4, and elevation of serum TSH. (nih.gov)
  • Rats injected with iohexol showed elevated urinary NGAL (11.94±6.79 ng/mL), serum creatinine (2.92±0.91 mg/dL) and urinary protein levels (11.03±9.68 mg/mg creatinine) together with histological evidence of tubular injury and iron accumulation. (alliedacademies.org)
  • Hematological, Biochemical, and Histological Measures in Wistar Male Rats Used to Assess Asafetida's Toxicity. (veterinaria.org)
  • Adult Sprague Dawley rats (either sex) weighed 200-300 gm were obtained from Central Animal House facility at Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab (India). (researchsquare.com)
  • Male rats of five different strains (Simonsen albino, Wistar, Long-Evans, Holtzman Sprague-Dawley, and Charles River Sprague-Dawley) were tested for their response to the U.S. Biochemical Corp. Remington low iodine diet containing 15-18 microgram I/kg. (nih.gov)
  • Long-Evans and Holtzman Sprague-Dawley rats responded relatively poorly to the low iodine diet. (nih.gov)
  • A combined repeated dose toxicity study with the reproduction/developmental toxicity screening test was carried out to evaluate the toxic potential ofthe test chemicalon reproductive performance and the development of offspring in male and female Sprague-Dawley rats. (europa.eu)
  • In summary, the present study provides clear evidence that the repeated oral exposure of the test chemical exerted strong adverse effect of testicular spermatogenesis and promotes the atrophy of male gonads in male Sprague-Dawley rats. (europa.eu)
  • The biochemical methods used will be mentioned further. (cdc.gov)
  • Methods: Neonatal male Wistar rats were injected with MSG (4 g/kg b. w., subcutaneously) from day 2 to 14 after birth, on alternate days. (greenmedinfo.com)
  • The pregnant Wistar albino rats were exposed to 50 and 150 ppm fluoride in drinking water and the pups born to them were used for experimentation. (fluoridealert.org)
  • However, it is inconvenient and expensive to maintain rats on a Remington low iodine diet for 3 months, and studies on the effect of severe iodine deficiency are much more rapidly performed using a rapidly responding strain such as the Simonsen albino. (nih.gov)
  • Biochemical, histopathological and ultra-structural studies were carried out on control, fibrotic and treated rats. (nature.com)
  • As a result, based on the interpretations of the clinical, radiographic, haematological, biochemical, and histopathological findings, the biocompatibility of HA/h-BN/Cs/Ct1 biocomposite materials has been revealed. (tubitak.gov.tr)
  • This study evaluated the effects of therapeutic and supra-therapeutic doses of CGV on reproductive function and biochemical indices in Wistar rats. (biomedcentral.com)
  • Therapeutic doses of CGV elevated reduced glutathione, superoxide dismutase, catalase and glutathione S-transferase, although, this was exceeded by supra-therapeutic doses and more in females than male rats. (biomedcentral.com)
  • In the present work, we describe the effects of dopamine depletion after the administration of 6-hidroxidopamine (6-OHDA) into the substantia nigra pars compacta of male rats submitted to the pilocarpine model of epilepsy. (scielo.br)
  • In male rats, no difference in body weights and food intake values were observed during the experiment. (europa.eu)
  • An experimental trial on subacute toxico-pathological studies of Acephate and its amelioration by Picrorhiza kurroa was attempted in thirty female Wistar rats for 28 days through haemato-biochemical assessment. (ijlr.org)
  • The experimental rats were divided into 5 groups each comprising of 6 rats. (ijlr.org)
  • Dose of Acephate was calculated as 1/20th of LD 50 (1127mg/kg) which was in powder form and mixed with propylene glycol as a vehicle and fed daily through oral gavage to the experimental rats. (ijlr.org)
  • Non-Status Epilepticus female rats show seizure-like behaviors in the chronic phase of Pilocarpine experimental model. (scielo.br)
  • The rats were assigned to experimental (21) and control groups (7). (twoday.net)
  • The rats in the experimental group were housed in a wooden barn with 7.5 m vertical distance to the power line. (twoday.net)
  • This experimental animal study investigated the simultaneous impact of iron and vitamin D on AKI induced by Iohexol, an iodinated, non-ionic monomeric radiocontrast agent in Wistar rats. (alliedacademies.org)
  • Out of 36 healthy male Wistar rats, saline was injected into six control rats (group 1) and Iohexol into the remaining 30 experimental rats (groups 2 to 6 comprising six rats each). (alliedacademies.org)
  • The amount of interstitial connective tis- experimental data on chronic health effects been observed in hamsters that chronically sue in the lung also differs, with rats having of inhaled particles come from rats. (cdc.gov)
  • Randomização de 32 ratos Wistar machos em quatro grupos: Controle (CG), Exposição à Fumaça (ESG), Antioxidante (AG) e Exposição à Fumaça+Antioxidante (ESAG). (bvsalud.org)
  • 0.05) lower elevated plasma lipids while the biochemical alterations as indicated by elevated aminotransferases, alkaline phosphatase, creatinine and urea induced by Pb were all lowered. (cput.ac.za)
  • This study investigates a possible protective effect of red palm oil (RPO) on Pb-induced lipid dysfunction and biochemical alterations in the plasma of Wistar rats. (cput.ac.za)
  • This study showed that RPO administration either before or after lead exposure reverses Pb-induced lipid dysfunction and biochemical alterations in the plasma of Wistar rats. (cput.ac.za)
  • Pre and post natal exposure of fluoride induced oxidative macromolecular alterations in developing central nervous system of rat and amelioration by antioxidants. (fluoridealert.org)
  • Elevation in markers of oxidative stress, alterations in other monoamines were observed in injured rats, whereas vinpocetine treated rats showed significant recovery with improved alterations in cognitive and motor functions and also restored traumatic brain injury induced biochemical alterations. (researchsquare.com)
  • No death and alterations in general conditions were observed among the female rats during the test chemical administration. (europa.eu)
  • A total of 60 adult male Wistar rats weighing 300?500 g were used in the study. (tubitak.gov.tr)
  • For this, male Wistar rats ( Rattus norvegicus albinus) were randomly divided into 3 groups (n = 10/group) Control ( 0.9% saline solution ), LEV100 (100 mg/kg), and LEV300 (300 mg/kg). (bvsalud.org)
  • Forty-eight male Wistar rats were randomly divided into a control group, a fatigue group, an essential oil mixture (EOM) group, and a peppermint essential oil (PEO) group. (hindawi.com)
  • The rats were randomly divided into 2 groups named A (uncoated/control) and B (biocomposite coated). (tubitak.gov.tr)
  • Lipid profiles as well as liver and kidney function markers were measured in the plasma of all groups of rats. (cput.ac.za)
  • In addition, the effects of regular consumption of the dessert (5 g/day) on the lipid profile, immune system, and antioxidant/biochemical status of Wistar rats were also evaluated after 2 weeks of treatment. (fiocruz.br)
  • Biochemical Pharmacology, 15, 811-816. (scirp.org)
  • The disease is caused mainly by the Hantaan virus (HTNV), transmitted by the striped field mouse ( Apodemus agrarius ), and Seoul virus (SEOV), transmitted by the brown Norway rat ( Rattus norvegicus ) ( 4 , 6 ). (cdc.gov)
  • The reproductive NOAEL (No Observed Adverse Effect Level) for male SD rats was 12,5 mg/kg/day based on findings of necropsy, organ weight measurement, sperm test findings and histopathology. (europa.eu)
  • Our findings evidenced the cardioprotective effect of trans- resveratrol in rats exposed to cigarette smoke. (bvsalud.org)
  • 0.01) the aspartate amino transferase to alanine amino transferase (AST:ALT) ratio (0.37±0.01) of the rats. (scialert.net)
  • To assess sub-acute oral toxicity of Acephate and its amelioration with Picrorhiza kurroa in female Wistar rats through haemato-biochemical studies. (ijlr.org)
  • The mitigating effect of Ananas comosus (pineapple juice) extract on an aluminum-induced testicular toxicity in male Wistar rats was examined in this study. (springeropen.com)
  • Thus, this study investigated the influence of Arg on some biochemical markers of Mes associated with the brain function and on the brain histology of female Wistar rats. (scialert.net)
  • Thirty (30) female Wistar rats of 6-8 weeks age having 140-160 g body weight were procured from M/S Worckdht Research Center, MIDC, Aurangabad, (MS) 431006. (ijlr.org)
  • Seventy-two Wistar rats weighing 130 ± 15.8 g were grouped into two categories (male or female) of six rats per group. (biomedcentral.com)
  • Supra-therapeutic dose (3000 mg/kg CGV) decreased body weight in both male and female rats by 50% (F(1.5, 30) = 1.2, p = 0.041) and 62.7% (F(2.1, 30) = 0.38, p = 0.038) respectively in treated rats. (biomedcentral.com)
  • Also, female rat kidney revealed acute tubular necrosis at highest dose used in this study. (biomedcentral.com)
  • All the studies reported here were performed on rats (Wistar, female). (cdc.gov)
  • One experiment included female rats, and the limited data suggested that within a given strain there was no significant sex difference. (nih.gov)
  • Similarly, the food consumption in female rats is dropped significantly on day 3-6 of pre-mating period, on day 2 of pregnancy and day 4 of lactation in the two highest dose groups. (europa.eu)
  • Hypoglycemic and hypolipidemic effect of Vaccinium myrtillus L. leaf and Phaseolus vulgaris L. seed coat extracts in diabetic rats. (aaem.pl)
  • Anti-hyperglycemic effect of bilberry, blackberry and mulberry ultrasonic extracts on diabetic rats. (aaem.pl)
  • Two groups of rats (n = 8) were exposed to a single dose of 60 mg kg -1 b.wt. (scialert.net)
  • Our aim was to study neuronal transmission in hippocampal slices of male Wistar rats affected with a single dose of TMT (7.5 mg/kg, i.p.) during the first three weeks of its action. (nel.edu)
  • Fenugreek Seed Extract Prevents Fat Deposition in Monosodium Glutamate (MSG)-Obese Rats. (greenmedinfo.com)
  • Aim: To evaluate the preventive effects of an aqueous extract of Trigonella foenum-graecum seeds (AqE-TFG) on fat deposition and dyslipidemia in monosodium glutamate (MSG)-obese rats. (greenmedinfo.com)
  • In order to delve deeper into the molecular mechanisms underlying the observed effects, primary rat hippocampal neurons were used. (nature.com)
  • From day 43 to 70, MSG treated rats were administered orally with AqE-TFG (0.5 and 1.0 g/kg b. w. (greenmedinfo.com)
  • Male Wistar rats were randomized into four groups: Control Group (CG), Exposure to Smoke Group (ESG), Antioxidant Group (AG) and Exposure to Smoke plus Antioxidant Group (ESAG). (bvsalud.org)
  • We used 40 male offspring from 14 Wistar rats which received purple grape juice or water by gavage daily for 42 days at a dose of 7 microliters/g. (scirp.org)
  • More or less successful studies were devoted to the following problems which will be discussed in more detail here: 1) the dose-excretion relationship, 2) the biochemical background of binding and releasing of mercury, 3) chemicals accelerating excretion of mercury. (cdc.gov)
  • Because rats lack respiratory bron- age of particles in the interstitium is increased with increased dose (exposure concentration, years chioles, they have simple acini. (cdc.gov)
  • Injured rats were treated with different doses of vinpocetine for four weeks. (researchsquare.com)
  • Progressive increase of lysosomal enzyme activities in hippocampus associated with reduction of population spike in a rat model of neurodegeneration. (nel.edu)
  • This work demonstrates a time-dependent reduction of somatic response in the hippocampus of TMT affected rats during the first three weeks. (nel.edu)
  • 0.05) reduction in HDL-cholesterol was observed in Pb exposed rats compared with control. (cput.ac.za)
  • In the first experiment, 62% (15/24) of 6-OHDA pre-treated rats and 45% (11/24) of those receiving ascorbic acid as control solution progressed to motor limbic seizures evolving to SE, after the administration of pilocarpine. (scielo.br)
  • In the stratum radiatum, reduction of the slope of excitatory postsynaptic potential was not time-dependent but almost constantly reduced from the 1st to 3rd week after TMT administration (55-60%) compared to control rats. (nel.edu)
  • The rats of group 4 served as the control and were placed in laboratory conditions (The average value of the ELF was 0.75 +/- 0.05 V/m. (twoday.net)
  • The control group was given rat pellets and distilled water. (springeropen.com)
  • In this context, the present study was conducted to evaluate the anti-obesogenic effect of apple cider vinegar (ACV) in Wistar rats subjected to a high fat diet. (nih.gov)
  • To study the effect of the essential oils of Citrus sinensis L., Mentha piperita L., Syzygium aromaticum L., and Rosmarinus officinalis L. on physical exhaustion in rats. (hindawi.com)
  • Chronic unpredictable mild stress paradigm in male Wistar rats: effect on anxiety- and depressive-like behavior. (nel.edu)
  • Male Wistar/DV rats were used in this study to assess our modified 2-week model of CMS as a combination of psychosocial, physical and metabolic stressors and to compare the effect of acute administration of venlafaxine (VFX) and diazepam (DZP), either in stress or no stress conditions. (nel.edu)
  • 3H-dialkylhydrazines in the neuroendocrine system and their antigonadotropic effect in rats. (cdc.gov)
  • This study investigated the effect of the trans-resveratrol supplementation on the cardiac oxidative stress in rats exposed to cigarette smoke. (bvsalud.org)
  • Strain susceptibility and resistance to 1,2-dimethylhydrazine-induced enteric tumors in germfree rats (40146). (cdc.gov)
  • 13,14 ), and they have larger alveoli and The scientific and regulatory communities increase in lung tumors, although soot accu- alveolar ducts than rats ( 15 ). (cdc.gov)
  • Eighteen male Wistar rats (140±5g) were divided into 3 three equal groups. (nih.gov)
  • Hence, exposure to Arg may impair the brain function and possibly, worsen Mes related to brain function of the rats. (scialert.net)
  • We demonstrate for the first time at the cellular level that heat-activated ionic currents were potentiated after exposure to the cAMP activator forskolin in rat nociceptive neurons. (jneurosci.org)
  • exposure concentration on particle retention in histologic sections from rats and humans. (cdc.gov)
  • Rats were provided with standard pellet feed procured from M/S L.R. Pharmaceutical Company, Parbhani, Maharashtra, India. (ijlr.org)
  • After 21 consecutive days of intragastric gavage treatments , pilocarpine stimulated saliva secretion was collected for salivary biochemical analysis . (bvsalud.org)
  • Our observation that rats of different strains differ markedly in their responses to an iodine-deficient diet suggests that hereditary factors play an important role in this response. (nih.gov)
  • Study evaluated the biochemical and calorific content of different species of seagrasses. (stuartxchange.org)
  • In this study, it was aimed to investigate the effects of a novel biocomposite consisting of hydroxyapatite (HA), hexagonal boron nitride (h-BN), chitosan (Cs), and type 1 collagen (Ct1) on biocompatibility and fracture healing in rats. (tubitak.gov.tr)
  • Fatty acids composition and in vivo biochemical effects of Aleurites moluccana seed (Candlenut) in obese wistar rats. (webmd.com)
  • Very recently, beneficial effects of naringenin have been demonstrated in old rats. (hindawi.com)
  • A very recent publication has also provided evidence that Nar has beneficial effects in the livers of old rats [ 18 ]. (hindawi.com)
  • 1978. Effects of short-term administration of maleic hydrazide or hydrazine on rat hepatic microsomal enzymes. (cdc.gov)
  • Mild bronchiolar- monkeys and humans have more complex, non-neoplastic health effects of inhaled par- alveolar hyperplasia, which was much less larger acini than rats. (cdc.gov)
  • TMT administration to rats, we found a time-dependent reduction of postsynaptic neuronal firing, expressed by diminished population spike (PoS) amplitude recorded in the stratum pyramidale accompanied with marked increase in specific activity of NAGA to respective 111%, 163% and 252% in the 1st, 2nd and 3rd week compared to unaffected rats. (nel.edu)
  • 1987. The influence of physical activity in 1 ,2dimethylhydrazine induced colon carcinogenesis in the rat. (cdc.gov)
  • Brain section of Arg-treated rats revealed degeneration, characterized by necrosis, oedema and reduction of astrocytes. (scialert.net)
  • Traumatic brain injury in rats produced significant deteriotation of cognition and motor functions. (researchsquare.com)
  • The rat is commonly used species for toxicological studies in accordance with international recommendations. (europa.eu)
  • ences between rats and primates (humans humans, 57, 68, and 91% of the retained particulate material was located in the interstitium of and nonhumans) could affect sites of long- the lung in the nonminers, coal miners under the current standard, and coal miners under the term particle retention. (cdc.gov)
  • Loaded swimming to exhaustion was used as the rat fatigue model. (hindawi.com)
  • The Wistar strain is a well-known laboratory model with sufficient historical data. (europa.eu)
  • IgG antibodies against hantavirus were also identified in laboratory rats, which were used by these students for their scientific research. (cdc.gov)
  • Phylogenetic analysis showed that partial small segment sequences recovered from humans, laboratory rats, and local wild rats belonged to SEOV. (cdc.gov)
  • Hantavirus sequences recovered from humans and laboratory rats clustered within 1 of 3 lineages of SEOV circulating among local wild rats in Shenyang. (cdc.gov)
  • These results suggest that the HFRS outbreak in Shenyang was caused by SEOV that was circulating among local wild rats and had also infected the laboratory rats. (cdc.gov)
  • The first report showed that contact with hantavirus-infected laboratory rats caused a HFRS outbreak among 13 doctors and 1 veterinarian at medical research institutions in Japan ( 8 ). (cdc.gov)
  • Furthermore, 16 HFRS cases associated with laboratory rats occurred in 1983 in the Shanxi province ( 16 ). (cdc.gov)
  • the wild rats passed the virus to laboratory rats, which then infected humans. (cdc.gov)
  • The rats of group II were Acephate toxicated, the rats of group IV and V were toxicated with Acephate and treated with Picrorhiza kurroa. (ijlr.org)
  • Previous studies have shown the presence of 2 hantaviruses carried by rodents: HTNV, carried by striped field mice, and SEOV, carried by Norway rats in Shenyang ( 18 ). (cdc.gov)
  • A greater portion of However, an interspecies difference in Inconsistent results have been obtained the pulmonary parenchyma (composed of air response, with rats but not mice showing an in studies using mice. (cdc.gov)