Bioactive glass ceramics and polymers biomedical and dental materials. Medical search. Frequent questions

Materials that are used for biomedical or clinical applications are known as biomaterials. (wikipedia.org)
Gowsihan (Gowsh) Poologasundarampillai is a Birmingham Fellow in Biomaterials and Bioimaging at the Dental School. (birmingham.ac.uk)
It can be said that the most concerning complication of the implantation of biological materials in the human body is infection related to biomaterials 9 . (nature.com)
Dr. George E. STAN , Scientific researcher rank I (since 2017), born in 1981, graduated the Faculty of Materials Science and Engineering (SIM) - Section "Medical Engineering" at University Politehnica of Bucharest (UPB) (2005), has a MSc degree in Biomaterials (UPB) (2007), and a PhD degree in Materials Engineering (UPB) (2011). (infim.ro)
Preparation of porous hydroxyapatite scaffolds by combination of the gel-casting and polymer sponge methods: a new route for high quality, net-shape ceramics.Biomaterials. (9pdf.info)
Member of the Portuguese Ceramics and Glass Society and of the Portuguese Materials Society with the coordination of the Biomaterials Division. (ua.pt)
Bioactive glass is a group of surface active glass ceramic biomaterials, including pro-bioactive glass, bioglass. (rnrmarketresearch.com)
Due to the possible negative effects of titanium, the clinical application of implants made from different novel ceramic biomaterials has become more active. (biomedres.us)
Journal of Biomedical Materials Research - Part B Applied Biomaterials. (tmu.edu.tw)
In this context, diverse but complementary contributions are needed on new biomaterials, multi-signal patterning methodologies, multiscale modelling, advanced characterization and processing technologies for the desired biomedical and biotechnological applications. (european-mrs.com)
M. Geetha, A. K. Singh, R. Asokamani, A. K. Gogia, Ti based biomaterials, the ultimate choice for orthopaedic implants, Progress in Materials Science 54 (2009) 397-425. (iapchem.org)
B. D. Ratner, S. J. Bryant, Biomaterials: Where We Have Been and Where We Are Going, Annual Review of Biomedical Engineering 6 (2004) 41-75. (iapchem.org)

Among them, hydroxyapatite is most widely studied bioactive and biocompatible material. (wikipedia.org)
Hydroxyapatite, a type of calcium phosphate that is similar to the mineral component of bone, is the most commercially popular calcium phosphate coating for biomedical implants [ 1 ]. (omicsonline.org)
A systematic evaluation of mechanical and biocompatibility properties of different volume fractions of hydroxyapatite whiskers in comparison with three commercial dental composites filled with micro- and nanosilica particles was carried out. (hindawi.com)
Hydroxyapatite (HA), Ca 10 (PO 4 ) 6 (OH) 2 , was introduced since 1975 as filling material for intrabony defects [ 1 - 4 ]. (hindawi.com)
For this reason, in the recent five years hydroxyapatite particles and whiskers have been added as novel bioactive and biocompatible reinforcing filler in dental restorations. (hindawi.com)
In addition, hydroxyapatite whiskers (wHA) have been considered the best option as reinforcing filler in comparison with other whiskers based on carbon, ceramic, glass, metal, and polymer due to the absence of cytotoxicity effects [ 12 , 13 ]. (hindawi.com)
To overcome the present lack in the literature about hydroxyapatite based composite, we proposed a systematic analysis of the mechanical and biocompatibility performances of them in comparison with commercial dental composite. (hindawi.com)
Hydroxyapatite-glass nanocomposites. (dokumen.pub)

Background: One of the crucial factors influencing the longevity of anterior aesthetic dental restorations is the colour stability of resin composites. (researchgate.net)
Purpose To compare and contrast mechanical properties of experimental alkali-resistant (AR) glass fibre-reinforced composites (FRCs) silanised with one of three functional trialkoxysilanes: 3-methacryloxypropyltrimethoxysilane (3-MPS), 8-methacryloxypropyltrimethoxysilane (8-MOS) and 3-acryloxypropyltrimethoxysilane (3-APS). (researchgate.net)
Nowadays, in order to avoid limits affecting long-term durability of resin composites, dental materials companies are focusing their attention on the improvement of the mechanical and biological properties of filler. (hindawi.com)
Penumakala PK, Santo J, Thomas A (2020) A critical review on the fused deposition modeling of thermoplastic polymer composites. (dntb.gov.ua)
Yu Y et al (2020) Material characterization and precise finite element analysis of fiber reinforced thermoplastic composites for 4D printing. (dntb.gov.ua)
Glass-containing composites, polymer-nanoparticles composites for regenerative medicine. (ua.pt)
Fabrication of ceramic composites. (dokumen.pub)

In specific, his research group is involved in the development of novel hybrid bioinks for 3D bioprinting, bioactive glass and hybrid scaffolds for hard and soft tissue regeneration and their characterisation using advanced techniques available at Harwell Campus. (birmingham.ac.uk)
he produced the first, bioactive, Class II hybrids for bone regeneration using natural polymers, the first electrospinning of cotton-wool-like fibrous materials from sol-gel solutions and the first 3D printed organic/inorganic hybrid scaffolds directly from sol-gel solutions. (birmingham.ac.uk)
Here, he was one of the first to use X-ray microtomography (µCT) to non-destructively quantify the macroporous architecture, permeability and mechanical properties of bioactive glass scaffolds (BGS) (Fig. 1a). (birmingham.ac.uk)
Here, he produced the first 3D printed organic/inorganic hybrid scaffolds directly from sol-gel solution without employing any polymer or coagulation agents (Fig. 1h,i). (birmingham.ac.uk)
Fu Q, Saiz E, Rahaman MN, Tomsia AP (2011) Bioactive glass scaffolds for bone tissue engineering: state of the art and future perspectives. (springer.com)
However, hydrogel scaffolds have several limitations, such as weak mechanical property and a lack of bioactive property. (mdpi.com)
In this review, we introduce the broad application of β-TCP in tissue engineering and discuss the different approaches that β-TCP scaffolds are customized, including physical modification (e.g., pore size, porosity and roughness) and the incorporation of metal ions, other materials (e.g., bioactive glass) and stem cells (e.g., mesenchymal stem cells). (frontiersin.org)
Seitz, H.: 3D Printing of Piezoelectric and Bioactive Barium Titanate-Bioactive Glass Scaffolds for Bone Tissue Engineering. (uni-rostock.de)
Her research interests include the preparation and design of materials and scaffolds for in vitro and in vivo fundamental studies, and a further focus is the provision of useful tools to assess mechanisms that govern cell behavior in regenerative medicine. (ibecbarcelona.eu)

They are bioactive and biocompatible in nature. (wikipedia.org)
Bioactive and biocompatible pieces of HA/sol-gel glass mixtures obtained by the gel-casting method: a new route for high quality, net-shape ceramics. (9pdf.info)
ISO 13356:2015 specifies the requirements and corresponding test methods for a biocompatible and bio-stable ceramic bone-substitute material based on yttriastabilized tetragonal for use as a material for surgical implants. (biomedres.us)
Biocompatible materials are used to repair or replace joints, fractured, or otherwise damaged bone. (iapchem.org)

Mussel-inspired polydopamine composite mesoporous bioactive glass nanoparticles: an exploration of potential metal-ion loading platform and in vitro bioactivity. (us.es)
Effect of boron-doped mesoporous bioactive glass nanoparticles on C2C12 cell viability and differentiation: potential for muscle tissue application. (us.es)

Biodegradable polymers are niche market materials finding focused applications, including agricultural applications such as mulch films, flowerpots and controlled-release fertilisers and packaging items such as carrier bags and food wrapping and containers. (chemtec.org)
Rapra's Handbook of Biodegradable Polymers is a complete guide to the subject of biodegradable polymers and is ideal for those new to the subject or those wanting to supplement their existing knowledge. (chemtec.org)
The book goes on to consider the characteristics, processability and application areas for biodegradable polymers, with key polymer family groups discussed. (chemtec.org)
This work was truly novel in the field of Class II biodegradable hybrids for biomedical applications and resulted in a patent application which was licenced to RepRegen Ltd (UK) and 6 high impact publications. (birmingham.ac.uk)
Synthetic biodegradable polymers. (dokumen.pub)

As such, surface modification with ceramic coatings is required in order to achieve proper biomedical features and enhance their overall behavior in the human body. (infim.ro)
Glass windows, which can also act as displays and play a current information, resource-saving lightweight membrane cushion construction with highly functionalized films or the future of packaging materials - at the "12 ICCG - International Conference on coatings on glass and plastics" in Würzburg, Germany 280 experts from industry and academia discussed these possible future trends. (fraunhofer.de)

Postiglione G et al (2015) Conductive 3D microstructures by direct 3D printing of polymer/carbon nanotube nanocomposites via liquid deposition modeling. (dntb.gov.ua)
Polymer-based nanocomposites. (dokumen.pub)
Biomedical nanocomposites. (dokumen.pub)

However, Ti-based materials suffer from limited biocompatibility and inertness when implanted for extended periods. (infim.ro)
Biocompatibility and introduction to biology": Biomedical Engineering, Politecnico di Milano, sede distaccata presso San Raffaele, Segrate Mi, Italy) from 1994-1997. (unitn.it)
The biocompatibility and biological activity of these glasses have led to their extensive research as implants in humans to repair and replace diseased or damaged bone. (rnrmarketresearch.com)

The same critical element epplies in other joint replacements, in the hundreds of thousands of dental implants performed each year, and in a widening range of veterinary applications. (edu.au)
However, additional data are still needed to confirm the long-term predictability of dental implants in general. (biomedres.us)
In order to bring dental implants into markets, they should firstly pass several mechanical tests like fatigue and dynamical loading tests. (biomedres.us)
Loading tests for dental implants can be denoted according to predefined standards or norms (i.e. (biomedres.us)
However, this standard is not usually applicable for testing dental implants. (biomedres.us)
ISO DIN 14801:2016 [previously known as ISO 14801:2007] specifies a method of dynamic testing of single post endosseous dental implants of the trans mucosal type in combination with their premanufactured prosthetic components [13,14], and is used in 162 member countries around the world. (biomedres.us)
It is most useful for comparing endosseous dental implants of different designs or sizes [15]. (biomedres.us)
This international standard is not a test of the fundamental fatigue properties of the materials from which the endosseous implants and prosthetic components are made, and, moreover, is not applicable to dental implants with endosseous lengths shorter than 8 mm nor to magnetic attachments. (biomedres.us)
While ISO 14801:2016 simulates the functional loading of an endosseous dental implant under "worst case" conditions, it is not applicable for predicting the in vivo performance of an endosseous dental implant or dental prosthesis, particularly if multiple endosseous dental implants are used for a dental prosthesis. (biomedres.us)
In recent years many different biomedical implants have been created for prolonged usage within the human body. (iapchem.org)

Titanium and titanium alloys are commonly used as dental implant materials. (biomedres.us)
Tribological characteristics, the main issue for joint implant materials. (dokumen.pub)
The mechanical properties of the implant materials were most important and had a considerable impact on the process of bone restoration. (iapchem.org)

The loss from and water content modification in of the cells (cellular water loss) with age is a serious problem for several organs and it can alter the functional behavior of biomedical apparati. (articlesfactory.com)
By placing the samples of the mentioned study in a warm fluid of 60°C during the dynamic loading procedure, the applied testing protocol was designed to account for the specific nature of zirconia ceramics and its behavior in aqueous environments. (biomedres.us)

In bioceramics, flaws influence the reliability and strength of the material during implantation and fabrication. (wikipedia.org)
Green ceramic machining: A top-down approach for the rapid fabrication of complex-shaped ceramics. (9pdf.info)
Mohd-Puad NAS et al (2020) Review on the fabrication of fused deposition modelling (FDM) composite filament for biomedical applications. (dntb.gov.ua)

Influence of copper-strontium co-doping on bioactivity, cytotoxicity and antibacterial activity of mesoporous bioactive glass. (us.es)

To simulate intraoral aging to the extent possible and, in particular, address the degradation susceptibility of metastable zirconia ceramics, an experimental setup by Spies et al. (biomedres.us)
Consequently, severe immunocompatibility problems and poor mechanical and degradation properties in synthetic polymers ensue. (afpm.org.my)

Simpson RL, Wiria FE, Amis AA, Chua CK, Leong KF, Hansen UN, Chandrasekaran M, Lee MW (2008) Development of a 95/5 poly(L-lactide-co-glycolide)/hydroxylapatite & beta-tricalcium phosphate Scaffold as bone replacement material via selective laser sintering. (springer.com)
In 2014, he was awarded the "Racquel LeGeros Award" of the "International Society for Ceramics in Medicine" for his contribution to calcium phosphate research. (bioceramics33.org)
S. Bose, S. Tarafder, Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review, Acta Biomaterialia 8 (2012) 1401-1421. (iapchem.org)

Gowsh produced both natural and synthetic polymer hybrids that showed synergistic effect on mechanical properties while maintaining bioactivity. (birmingham.ac.uk)
Her primary area of research and publishing involves dental ceramics, mechanical properties, clinical longitudinal trials and failure analysis using fractography. (bioceramics33.org)
biological and mechanical properties for several biomedical applications (Montheard et al. (articlesfactory.com)
Bio-functional and mechanical properties of the prosthetic materials can be then altered or, conversely, they can alter the physiological equilibrium altering the aqueous medium composition. (articlesfactory.com)

Kaur, Ghadirinejad, Oskouei, An Overview on the Tribological Performance of Titanium Alloys with Surface Modifications for Biomedical Applications, Lubricants 7 (2019) 65. (iapchem.org)

For any material to be classified for biomedical applications, three requirements must be met. (wikipedia.org)
The biomaterial term is used for materials that can be used in biomedical and clinical applications. (wikipedia.org)
Gowsh is now commercialising this technology with industrial partners for dental and wound healing applications. (birmingham.ac.uk)
Poly (methyl methacrylate) (PMMA), is an acrylic polymer substance that is mostly used for denture base applications. (researchgate.net)
The presence of Si on the Ti surface is quintessential for a strong, durable silane‐based adhesion utilized in several dental applications. (researchgate.net)
Synthesis and Optimisation of Novel Fluormica Glass-Ceramics for Dental CAD/CAM Applications. (qmul.ac.uk)
All synthetic and natural materials to be used in biomedical applications that involve the contact with human body need to be investigated for their physical and chemical modification induced by the human physiological fluids contact and sorption. (articlesfactory.com)
Ngo TD et al (2018) Additive manufacturing (3D printing): a review of materials, methods, applications and challenges. (dntb.gov.ua)
Harun W et al (2018) A review of powdered additive manufacturing techniques for Ti-6al-4v biomedical applications. (dntb.gov.ua)
Hence, synthesized hydrogel could be a potential candidate for medical imaging as well as tissue engineering applications as a tissue expander, coating material, biosensor, and drug delivery system. (afpm.org.my)
Therefore, it is very important to carry out studies on the sterilization methods of the sample's material, since translational medicine is intended for in vivo applications. (bvsalud.org)

Daminabo SC et al (2020) Fused deposition modeling-based additive manufacturing (3D printing): techniques for polymer material systems. (dntb.gov.ua)
Mohan N et al (2017) A review on composite materials and process parameters optimisation for the fused deposition modelling process. (dntb.gov.ua)

Prof. Scherrer is the current President of the University Clinics of Dental Medicine (2022-2025). (bioceramics33.org)
The global Bioactive Glass market size was valued at USD 201.22 Million in 2022 and will reach USD 289.66 Million in 2028, with a CAGR of 6.26% during 2022-2028. (rnrmarketresearch.com)

Her group conducts several transference and translational projects with pharma and biomedical device industry partners, and participates actively in European projects. (ibecbarcelona.eu)

Maria Helena Fernandes is Associate Professor at the Department of Materials and Ceramic Engineering, University of Aveiro (UA) and member of the Associate Laboratory CICECO Aveiro Institute of Materials - Center for Research in Ceramics and Composite Materials, University of Aveiro. (ua.pt)

All synthetic and natural hydrophilic materials used in biomedical application should be investigated and characterized for their interactions with aqueous environments. (articlesfactory.com)

A number of methods are available for determining the tensile strength of materials, such as the bending flexural test, the biaxial flexural strength test and the weibull approach. (wikipedia.org)
Furthermore, these materials exhibit tensile strength,surface roughness, and wettability values appropriate for their finaluse as cardiac patches. (ibecbarcelona.eu)
Metals have the highest tensile strength compared to other materials, followed by polymers and ceramics (except for zirconia). (iapchem.org)

Seitz, H.: 3D printing of aluminum oxide via Composite Extrusion Modeling using a ceramic injection molding feedstock. (uni-rostock.de)

Evolution of ceramic composite hip prostheses. (dokumen.pub)

BGS are brittle (Fig. 1b, µCT after brittle failure), therefore to improve on toughness GP developed the first covalently cross-linked Class II bioactive silica / poly(g-glutamic acid) hybrid using an organosilane, 3-glycidoxypropyltrimethoxysilane (GPTMS) as the coupling agent (Fig. 1c,d). (birmingham.ac.uk)

A new break-through came during his first PDRA position in Nagoya Institute of Technology (NIT), Japan, while working on electrospinning of inorganic as well as organic/inorganic hybrid materials for bone regeneration (Fig. 1e-g). (birmingham.ac.uk)
He studied Inorganic, Analytical and Organic Chemistry, following he completed his PhD at Max Planck Institute for Materials Research, Stuttgart. (bioceramics33.org)

In brittle materials like bioceramics, cracks easily propagate when the material is subject to tensile loading, unlike compressive loading. (wikipedia.org)

Dental & Orthodontics Report: Can Innovative Products Brace up Dentistry Market Growth? (signicent.com)

In recent years, tissue engineering has evolved considerably, due to the problems in the biomedical area concerning tissue regeneration therapies. (bvsalud.org)

Composite dental restorations are commonly used to restore cavitated carious lesions. (signicent.com)
To improve the long-term survival of restorations, antibacterial agents have been added to dental materials. (signicent.com)

It is clinically important because it indicates the selected biomaterial has similar deformable properties with the material it is going to replace. (wikipedia.org)
Hardness is one of the most important parameters for comparing properties of materials. (wikipedia.org)
Gowsh demonstrated for the first time, electrospinning of cotton-wool-like materials directly from sol-gel solutions and fully characterised the formation, structure and properties of the materials. (birmingham.ac.uk)
However, bleaching agents can deteriorate surface properties of CAD-CAM materials. (researchgate.net)
A central aspect is then the ability to optimize the functional properties with high spatial resolution, creating materials that are able to control the interaction with the biological surrounding at the nanoscale thus guiding the responses of biomolecules, cells and tissues. (european-mrs.com)

Ag-doped carbon nanotubes (CNT) to PMMA-based (PMMA and MMA) denture base material on the impact strength, microhardness, and antimicrobial activ. (researchgate.net)

Chemistry of Materials. (aston.ac.uk)
Polymer Chemistry. (aston.ac.uk)
Ceramic forming using enzyme catalyzed reactions.Materials Chemistry and Physics. (9pdf.info)

This in vitro study aimed to investigate the effect of in-office bleaching agents on Vickers hardness and surface topography of polished and unpolished dental CAD-CAM composite. (researchgate.net)

She currently serves on the Editorial Boards of the JADA Foundation Science, and the Swiss Dental Journal. (bioceramics33.org)
2] LEWIS, Jennifer A. Journal of the American Ceramic Society. (9pdf.info)
Journal of the American Ceramic Society. (9pdf.info)
Journal Of The European Ceramic Society [online]. (9pdf.info)
Journal of Biomedical Materials Research Part A. 2005, 75A(1): 63-72. (9pdf.info)
Journal of Dental Sciences. (tmu.edu.tw)
Materials is an international peer-reviewed , open access journal on materials science and engineering published semimonthly online by MDPI. (mdpi.com)
European Polymer Journal. (aalto.fi)
H. M. Kim, F. Miyaji, T. Kokubo, T. Nakamura, Effect of heat treatment on apatite-forming ability of Ti metal induced by alkali treatment, Journal of Materials Science: Materials in Medicine 8 (1997) 341-347. (iapchem.org)

Mogan J et al (2021) A review of FDM and graphene-based polymer composite. (dntb.gov.ua)
Kumar S et al (2021) 3D printed tensile and flexural prototypes of thermoplastic matrix reinforced with multi-materials: a statistical analysis. (dntb.gov.ua)

Bleaching and whitening have become popular methods for enhancing dental aesthetics. (researchgate.net)
Novel Powder-Processing Methods for Advanced Ceramics. (9pdf.info)

We conducted IP, technology and market research to scout innovations in dental and orthodontics healthcare to solve the existing challenges. (signicent.com)
Dr. Sabine Amberg-Schwab from the Fraunhofer Institute for Silicate Research ISC in Wurzburg is on to something that could solve the problem - a new class of material called bioORMOCER ® s. (fraunhofer.de)
However, as it is a highly anisotropic material, our research focused on the impact that different window layers have on the growth of antimony selenide. (mdpi.com)

This includes dental replacements and bone joining or replacements for medical and clinical application. (wikipedia.org)

Anatomy11

Diseases6

Chemicals and Drugs54

Analytical, Diagnostic and Therapeutic Techniques and Equipment40

Psychiatry and Psychology1

Phenomena and Processes16

Disciplines and Occupations7

Anthropology, Education, Sociology and Social Phenomena6

Technology, Industry, Agriculture35

Humanities1

Information Science11

Named Groups8

Health Care25

Biomaterials12

Hydroxyapatite8

Composites7

Scaffolds9

Biocompatible4

Nanoparticles2

Biodegradable5

Coatings2

Nanocomposites3

Biocompatibility3

Implants10

Implant materials3

Behavior2

Fabrication3

Mesoporous1

Degradation2

Phosphate3

Mechanical properties4

Alloys1

Applications11

Deposition2

20222

Translational1

Laboratory CICECO Aveiro Institute of Materials1

Synthetic1

Tensile strength3

Oxide1

Prostheses1

Poly1

Inorganic2

Bioceramics1

Dentistry1

Tissue regeneration1

Restorations2

Properties5

Carbon1

Chemistry3

Vitro1

Journal9

20212

Methods2

Research3

Clinical1