• high
  • This mediates high frequency firing due to the phosphorylation sites located within the channel via kinases and a major calcium influx typical of all neurons. (wikipedia.org)
  • immune
  • Winfrey, Ron 2004-09-29 00:00:00 A full-length cDNA encoding a calreticulin-like protein was isolated by immune-screening a germinating castor bean endosperm cDNA library with antisera raised to the total lumenal fraction of purified plant endoplasmic reticulum. (deepdyve.com)
  • Calcium overlays and immune blot analysis confirmed the endoplasmic lumenal identity of this reticuloplasmin. (deepdyve.com)
  • specific
  • The properties of the proteins described here, and their ability to bind to atrial specific granules in a calcium-dependent manner, make them likely candidates in the search for regulatory proteins mediating atrial natriuretic peptide secretion. (ahajournals.org)
  • Active, GTP-bound Ras proteins interact with specific downstream effectors, that is, signalling or structural proteins that are ultimately responsible for mediating their cellular effects. (biologists.org)
  • Probing protein blots of endoplasmic reticulum subfractions with radio-iodinated calreticulin showed specific associations with various polypeptides including one identified as the abundant reticuloplasmin protein disulfide isomerase. (deepdyve.com)
  • addition
  • However, unlike fluorescent proteins, luciferases do not require an external light source, but do require addition of luciferin, the consumable substrate. (wikipedia.org)
  • effects
  • Marian Blanca Ramírez from the CSIC in Spain has been studying the effects of LRRK2, a protein associated with Parkinson's disease, on cell motility. (biologists.org)
  • evidence
  • p>This indicates the type of evidence that supports the existence of the protein. (uniprot.org)
  • Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. (uniprot.org)
  • shown
  • Annexin A2 has been shown to interact with Prohibitin, CEACAM1, S100A10, PCNA, complement Factor H, and a number of viral factors including the HPV16 minor capsid protein L2. (wikipedia.org)
  • formation
  • Consistent with this hypothesis, we observed increased coated platelet formation and more sustained calcium transients in SKO platelets compared to controls. (ahajournals.org)