Binds ligands drug screening assays antitumor. Medical search. Frequent questions

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Anatomy23

Cell Line CHO Cells Cell Line, Tumor Cell Membrane Tumor Cells, Cultured Cells, Cultured Dendritic Cells T-Lymphocytes Killer Cells, Natural CD8-Positive T-Lymphocytes T-Lymphocytes, Cytotoxic HeLa Cells Lymphocytes, Tumor-Infiltrating COS Cells CD4-Positive T-Lymphocytes Spleen Macrophages Jurkat Cells HT29 Cells Liver Cell Nucleus K562 Cells T-Lymphocytes, Regulatory

Organisms18

Cricetinae Mice, Nude Mice, Inbred BALB C Mice, Inbred C57BL Mice, SCID Adenoviridae Mice, Knockout Oncolytic Viruses Mice, Inbred DBA Escherichia coli Mice, Transgenic Mice, Inbred C3H Streptomyces Cattle Cricetulus Mice, Inbred Strains Cercopithecus aethiops Mice, Inbred ICR

Diseases23

Leukemia P388 Neoplasms, Experimental Melanoma, Experimental Sarcoma 180 Neoplasms Leukemia L1210 Carcinoma, Lewis Lung Melanoma Colonic Neoplasms Lung Neoplasms Sarcoma, Experimental Fibrosarcoma Neovascularization, Pathologic Mammary Neoplasms, Experimental Disease Models, Animal Breast Neoplasms Carcinoma, Ehrlich Tumor Leukemia L5178 Adenocarcinoma Leukemia, Experimental Ovarian Neoplasms Neoplasm Metastasis Prostatic Neoplasms

Chemicals and Drugs92

Ligands Recombinant Proteins Receptors, Cell Surface Antineoplastic Agents CD40 Ligand Fas Ligand Protein Antibiotics, Antineoplastic Cancer Vaccines Antibodies, Monoclonal Membrane Glycoproteins Recombinant Fusion Proteins RANK Ligand TNF-Related Apoptosis-Inducing Ligand Carrier Proteins Membrane Proteins DNA DNA-Binding Proteins Peptides Enediynes Antigens, Neoplasm Transcription Factors RNA, Messenger CD30 Ligand Antineoplastic Agents, Phytogenic Peptide Fragments OX40 Ligand Interferon-gamma Antigens, CD 4-1BB Ligand Oligopeptides Angiogenesis Inhibitors Proteins Interleukin-2 Doxorubicin Indoles Intercalating Agents Enzyme Inhibitors Immunotoxins Receptors, TNF-Related Apoptosis-Inducing Ligand DNA Primers Bacterial Proteins Antigens, CD95 Cytokines Tumor Necrosis Factor-alpha Ellipticines Cisplatin Nuclear Proteins Programmed Cell Death 1 Ligand 2 Protein Receptors, Immunologic Receptor, Epidermal Growth Factor Adjuvants, Immunologic Apoptosis Regulatory Proteins Receptors, Cytoplasmic and Nuclear DNA, Complementary Antigens, CD40 Neoplasm Proteins Thiazoles Cross-Linking Reagents Oligodeoxyribonucleotides Prodrugs Camptothecin Glycoproteins Interleukin-12 Antibodies Antineoplastic Agents, Alkylating Intercellular Signaling Peptides and Proteins Receptors, G-Protein-Coupled Naphthacenes Protein Kinase Inhibitors Antigens, CD80 Macromolecular Substances Pyridines Receptors, Tumor Necrosis Factor Zinostatin Paclitaxel Plicamycin RNA, Small Interfering Organometallic Compounds Antibodies, Neoplasm Repressor Proteins Topoisomerase I Inhibitors Pyrroles Proto-Oncogene Proteins Drug Carriers Quinazolines Intracellular Signaling Peptides and Proteins Lectins NK Cell Lectin-Like Receptor Subfamily K Liposomes Cell Adhesion Molecules RNA-Binding Proteins Trans-Activators

Analytical, Diagnostic and Therapeutic Techniques and Equipment48

Models, Molecular Drug Screening Assays, Antitumor Xenograft Model Antitumor Assays Transfection Neoplasm Transplantation Neoplasms, Experimental Melanoma, Experimental Immunotherapy Binding, Competitive Immunotherapy, Adoptive Flow Cytometry Crystallography, X-Ray Transplantation, Heterologous Lymphocyte Activation Inhibitory Concentration 50 Blotting, Western Genetic Therapy Injections, Intralesional Mutagenesis, Site-Directed Sarcoma, Experimental Oncolytic Virotherapy Magnetic Resonance Spectroscopy Tumor Burden Cloning, Molecular Models, Biological Reverse Transcriptase Polymerase Chain Reaction Surface Plasmon Resonance Sequence Alignment Mammary Neoplasms, Experimental Drug Design Immunohistochemistry Antineoplastic Combined Chemotherapy Protocols Disease Models, Animal Models, Chemical Radioligand Assay Enzyme-Linked Immunosorbent Assay Electrophoresis, Polyacrylamide Gel Drug Delivery Systems Drug Administration Schedule Drug Evaluation, Preclinical Combined Modality Therapy Amino Acid Substitution Injections, Intraperitoneal Drug Carriers Immunoblotting Leukemia, Experimental Spectrometry, Fluorescence Circular Dichroism

Phenomena and Processes58

Protein Binding Binding Sites Amino Acid Sequence Protein Structure, Tertiary Protein Conformation Signal Transduction Kinetics Base Sequence Sequence Homology, Amino Acid Transfection Mutation Apoptosis Dose-Response Relationship, Drug Molecular Structure Binding, Competitive Cell Proliferation Drug Synergism Structure-Activity Relationship Cell Survival Cell Division Cytotoxicity, Immunologic Lymphocyte Activation Inhibitory Concentration 50 Time Factors Phosphorylation Genetic Vectors Dimerization Promoter Regions, Genetic Gene Expression Regulation Molecular Conformation Cell Adhesion Protein Structure, Secondary Gene Expression Tissue Distribution Down-Regulation Substrate Specificity Cell Movement Stereoisomerism Cell Cycle Amino Acid Motifs Plasmids Cell Differentiation Solubility Tumor Escape Enzyme Activation Drug Resistance, Neoplasm Thermodynamics Gene Expression Regulation, Neoplastic Molecular Weight Cell Growth Processes Amino Acid Substitution Up-Regulation Nucleic Acid Conformation Hydrogen-Ion Concentration Cell Death Antibody-Dependent Cell Cytotoxicity Catalysis Protein Transport

Disciplines and Occupations2

Drug Design Immunohistochemistry

Technology, Industry, Agriculture1

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Ligands Protein Binding Molecular Sequence Data Binding Sites Amino Acid Sequence Models, Molecular Protein Structure, Tertiary Drug Screening Assays, Antitumor Protein Conformation Xenograft Model Antitumor Assays Cell Line Recombinant Proteins Signal Transduction Kinetics Receptors, Cell Surface Antineoplastic Agents Base Sequence Cricetinae CHO Cells Sequence Homology, Amino Acid Transfection Mutation CD40 Ligand Cell Line, Tumor Cell Membrane Fas Ligand Protein Mice, Nude Antibiotics, Antineoplastic Leukemia P388 Tumor Cells, Cultured Neoplasm Transplantation Neoplasms, Experimental Mice, Inbred BALB C Melanoma, Experimental Sarcoma 180 Mice, Inbred C57BL Apoptosis Cancer Vaccines Antibodies, Monoclonal Membrane Glycoproteins Neoplasms Dose-Response Relationship, Drug Immunotherapy Recombinant Fusion Proteins Leukemia L1210 Molecular Structure Binding, Competitive Cell Proliferation Cells, Cultured RANK Ligand Drug Synergism TNF-Related Apoptosis-Inducing Ligand Immunotherapy, Adoptive Carrier Proteins Flow Cytometry Mice, SCID Membrane Proteins Crystallography, X-Ray Structure-Activity Relationship DNA Cell Survival Dendritic Cells T-Lymphocytes DNA-Binding Proteins Killer Cells, Natural Peptides Cell Division Enediynes Antigens, Neoplasm Cytotoxicity, Immunologic Transplantation, Heterologous Transcription Factors CD8-Positive T-Lymphocytes RNA, Messenger Carcinoma, Lewis Lung Lymphocyte Activation Melanoma CD30 Ligand Antineoplastic Agents, Phytogenic Inhibitory Concentration 50 T-Lymphocytes, Cytotoxic Blotting, Western Genetic Therapy Colonic Neoplasms Peptide Fragments Injections, Intralesional Lung Neoplasms OX40 Ligand Time Factors Mutagenesis, Site-Directed Phosphorylation Genetic Vectors Adenoviridae Mice, Knockout Sarcoma, Experimental Oncolytic Virotherapy Interferon-gamma Antigens, CD Magnetic Resonance Spectroscopy Fibrosarcoma

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