Cell SurvivalSurvival RateDisease-Free SurvivalApoptosisSurvivalSurvival AnalysisGraft SurvivalSignal TransductionProtein BindingCell Line, TumorTime FactorsMolecular Sequence DataCells, CulturedCell LineTreatment OutcomeCell ProliferationPhosphorylationCell DeathKaplan-Meier EstimateBinding SitesProto-Oncogene ProteinsAmino Acid SequenceDNA-Binding ProteinsProto-Oncogene Proteins c-aktProtein-Serine-Threonine KinasesMutationRetrospective StudiesPhosphatidylinositol 3-KinasesBlotting, WesternAntineoplastic AgentsBase SequenceRNA, Small InterferingTransfectionMice, Inbred C57BLNeoplasm StagingTranscription FactorsEnzyme ActivationMice, KnockoutImmunohistochemistryProportional Hazards Modelsbcl-X ProteinProtein Structure, TertiaryRNA, MessengerProto-Oncogene Proteins c-bcl-2Follow-Up StudiesTumor Cells, CulturedModels, BiologicalBreast Neoplasmsbcl-Associated Death ProteinGene Expression RegulationAntineoplastic Combined Chemotherapy ProtocolsGene Expression Regulation, NeoplasticCarrier ProteinsLung NeoplasmsRecombinant ProteinsCaspase 3Cell DivisionCombined Modality TherapyReverse Transcriptase Polymerase Chain ReactionCell DifferentiationMembrane ProteinsNuclear ProteinsRNA InterferenceNF-kappa BAutophagyPrognosisDose-Response Relationship, DrugCaspasesNeoplasmsEnzyme InhibitorsTumor Suppressor Protein p53Promoter Regions, GeneticApoptosis Regulatory ProteinsMice, TransgenicRecombinant Fusion ProteinsHeLa CellsDown-RegulationCell CycleAdenocarcinomaGene Knockdown TechniquesGene ExpressionNeoplasm MetastasisUp-RegulationIn Situ Nick-End LabelingCisplatinNeoplasm Recurrence, LocalDNA DamageTumor Markers, BiologicalDNANeuronsMultivariate AnalysisMice, Inbred BALB CDisease Models, AnimalAntibodies, MonoclonalCell NucleusRadiation ToleranceNeoplasm ProteinsKineticsChromonesDrug Resistance, Neoplasm