Tumor Suppressor Protein p53Tumor Suppressor ProteinsGenes, Tumor SuppressorVon Hippel-Lindau Tumor Suppressor ProteinTumor Suppressor Protein p14ARFRetinoblastoma ProteinCell Line, TumorProto-Oncogene Proteins c-mdm2Molecular Sequence DataProtein BindingMutationNuclear ProteinsGenes, p53DNA-Binding ProteinsApoptosisNeurofibromin 2Gene Expression Regulation, NeoplasticTranscription FactorsCell LineTransfectionAdenomatous Polyposis Coli ProteinCell CycleAmino Acid SequenceBase SequenceCyclin-Dependent Kinase Inhibitor p16Tumor Cells, CulturedUbiquitin-Protein LigasesPromoter Regions, GeneticGenes, SuppressorProto-Oncogene ProteinsPTEN PhosphohydrolaseCell Cycle ProteinsCyclin-Dependent Kinase Inhibitor p21Signal TransductionCell Transformation, NeoplasticCell ProliferationPhosphorylationDNA DamageBinding SitesProtein Structure, TertiaryCell DivisionNeoplasm ProteinsRepressor ProteinsLigasesNeoplasmsCyclinsE2F Transcription FactorsTranscription, GeneticRNA, MessengerProteinsBlotting, WesternDown-RegulationTranscriptional ActivationTumor Markers, BiologicalCarrier ProteinsGene SilencingRecombinant Fusion ProteinsE2F1 Transcription FactorHeLa CellsProtein-Serine-Threonine KinasesSuppressor of Cytokine Signaling ProteinsGene Expression RegulationTranscription Factor DP1RNA InterferenceFibroblastsCells, CulturedDNA MethylationSuppression, GeneticLoss of HeterozygosityOncogene Proteins, ViralReverse Transcriptase Polymerase Chain ReactionRNA, Small InterferingKidney NeoplasmsPapillomavirus E7 ProteinsCell NucleusGene DeletionTrans-ActivatorsWT1 ProteinsRetinoblastoma-Binding Protein 1Tumor BurdenDNA PrimersRetinoblastoma-Like Protein p107Tumor Necrosis Factor-alphaRecombinant ProteinsMembrane ProteinsDNAImmunohistochemistryProteasome Endopeptidase ComplexWilms TumorBreast NeoplasmsModels, BiologicalDNA, NeoplasmMice, NudeG1 PhaseCell AgingHypoxia-Inducible Factor 1, alpha SubunitMice, KnockoutGenes, RetinoblastomaUbiquitinCyclin-Dependent Kinases