• liver
  • Your liver makes a digestive juice called bile. (icdlist.com)
  • Known risk factors for cholangiocarcinoma include primary sclerosing cholangitis (an inflammatory disease of the bile ducts), infection with the parasitic liver flukes Opisthorchis viverrini or Clonorchis sinensis, some congenital liver malformations, and exposure to Thorotrast (thorium dioxide), a chemical formerly used in medical imaging. (wikipedia.org)
  • The most common physical indications of cholangiocarcinoma are abnormal liver function tests, jaundice (yellowing of the eyes and skin occurring when bile ducts are blocked by tumor), abdominal pain (30%-50%), generalized itching (66%), weight loss (30%-50%), fever (up to 20%), and changes in the color of stool or urine. (wikipedia.org)
  • To some extent, the symptoms depend upon the location of the tumor: patients with cholangiocarcinoma in the extrahepatic bile ducts (outside the liver) are more likely to have jaundice, while those with tumors of the bile ducts within the liver more often have pain without jaundice. (wikipedia.org)
  • Such laboratory findings suggest obstruction of the bile ducts, rather than inflammation or infection of the liver parenchyma, as the primary cause of the jaundice. (wikipedia.org)
  • The parasitic worm is as long as 10 to 25mm and lives in the bile ducts of the liver. (wikipedia.org)
  • pancreas
  • this is bound by the junction of cystic and common bile ducts, junction of the second and third parts of the duodenum, and the junction of the neck and body of the pancreas. (wikipedia.org)
  • MRI is a great method to visualize the pancreatic ducts, PET scanning can reveal the metabolic activity of a tumor, EUS requires slight sedation but provides excellent detail and biopsies can be performed at the same time, and ERCP can be used to visualize the duct system of the pancreas and stents (small tubes to re-establish the flow of secretions such as bile) can be placed during the ERCP procedure. (wikipedia.org)
  • Adenocarcinoma
  • For example, neoplasms characterized by high-grade features, invasive glands and or signet ring cells, are termed adenocarcinoma in pathology literature. (wikipedia.org)
  • disease
  • In the Western world, the most common of these is primary sclerosing cholangitis (PSC), an inflammatory disease of the bile ducts which is closely associated with ulcerative colitis (UC). (wikipedia.org)