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  • acetyl
  • The HADHB protein catalyzes the final step of beta-oxidation, in which 3-ketoacyl CoA is cleaved by the thiol group of another molecule of Coenzyme A. The thiol is inserted between C-2 and C-3, which yields an acetyl CoA molecule and an acyl CoA molecule, which is two carbons shorter. (wikipedia.org)
  • NADH
  • S -3-hydroxyacyl-CoA + NAD + = 3-oxoacyl-CoA + NADH. (rcsb.org)
  • Be able to describe the structural changes undergone by the electron carriers NADH and FADH 2 in their oxidation-reduction cycle in terms that explain their suitability as electron carriers. (wikipremed.com)
  • The complete breakdown of a fatty acid not only generates acetyl-CoA molecules, but it also generates energy in the form of NADH. (wikipedia.org)
  • Reaction
  • The CoA thioester derivatives bind in a characteristic hooked shape and a conserved tunnel binds the pantetheine group of CoA, which links the 3'-phosphate ADP binding site to the site of reaction. (wikipedia.org)
  • It is convenient to think of this reaction as marking the "starting point" of the cycle, as this is when fuel - acetyl-CoA - is added to the cycle, which will be dissipated as CO2 and H2O with the release of a substantial quantity of energy captured in the form of ATP, during the course of each turn of the cycle. (wikipedia.org)
  • The reaction mechanism is detailed in Figure 1, and the base that initiates the isomerization and NH groups that stabilize the intermediate are located on the active site of enoyl-coA isomerase. (wikipedia.org)
  • Dienoyl CoA
  • The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. (wikipedia.org)
  • 1998). "Delta3,5-delta2,4-dienoyl-CoA isomerase from rat liver. (wikipedia.org)
  • Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. (abcam.com)
  • Dienoyl-CoA isomerase, which catalyses the isomerisation of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. (wikipedia.org)
  • enoyl-CoA-hydratase Acyl-CoA synthetase Electron transport flavoprotein Pro bability of beta-oxidation 2,4-Dienoyl-CoA reductase Negative regulator for fad high probability forex, and positive activator of fabA Utilization of trans-unsaturated fatty acids Methylmalonyl-CoA mutase (MCM) 2226, 2229 323, 1478 2244 Forex currency trading foreign exchange newforextradingcom, 451, 743 445 1696 4. (retzepti.ru)
  • mitochondrion
  • In order for the acyl-CoA to enter the mitochondrion the carnitine shuttle is used: Acyl-CoA is transferred to the hydroxyl group of carnitine by carnitine palmitoyltransferase I, located on the cytosolic faces of the outer and inner mitochondrial membranes. (wikipedia.org)
  • Novel
  • Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity - Novel mechanistic insight from real-time analysis of oxidative phosphorylation. (bioportfolio.com)
  • reaction
  • Of particular significance is the finding that H 2 formation in C. pasteurianum is coupled to the ferredoxin-dependent butyryl-CoA dehydrogenase catalyzed reaction, which significantly affects the redox balance and thus the product selectivity. (biomedcentral.com)
  • Chains with an odd-number of carbons are oxidized in the same manner as even-numbered chains, but the final products are propionyl-CoA and Acetyl CoA Propionyl-CoA is first carboxylated using a bicarbonate ion into D-stereoisomer of methylmalonyl-CoA, in a reaction that involves a biotin co-factor, ATP, and the enzyme propionyl-CoA carboxylase. (wikipedia.org)
  • The CoA thioester derivatives bind in a characteristic hooked shape and a conserved tunnel binds the pantetheine group of CoA, which links the 3'-phosphate ADP binding site to the site of reaction. (wikipedia.org)
  • It is convenient to think of this reaction as marking the "starting point" of the cycle, as this is when fuel - acetyl-CoA - is added to the cycle, which will be dissipated as CO2 and H2O with the release of a substantial quantity of energy captured in the form of ATP, during the course of each turn of the cycle. (wikipedia.org)
  • keto
  • 6-oxo camphor hydrolase, which catalyses the desymmetrization of bicyclic beta-diketones to optically active keto acids. (wikipedia.org)